the effect of systemic chemotherapy on minimal residual disease in the blood and bone marrow of patients with inflammatory breast cancer
Báo cáo khoa học: "Intraoperative frozen section assessment of sentinel lymph nodes in the operative management of women with symptomatic breast cancer" ppt
... evaluation of sentinel lymph nodes in patients with breast cancer It allows immediate decision making regarding the need for ALND in the majority of patients 16 17 Competing interests The authors ... evident in their sentinel node) had non-sentinel nodal metastases evident on full examination of the residual lymphatic basin Sentinel Node Identification and frozen section analysis There were ... T-staging are all too often inaccurate[3] Any uncertainty surrounding the "completeness" of the initial surgery may weigh heavily on the minds of women undergoing lymphatic mapping due to the interval...
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Báo cáo y học: "Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response" potx
... between baseline and months decrease in the population of memory B cells both in the PB and in the BM of RA patients Depletion of total and activated B cells is a specific effect of rituximab therapy ... **P < 0.05 therefore assessed the effect of rituximab therapy on B-cell HLA-DR expression, a marker of activation and antigen-presenting function The proportion of HLA-DR+ cells within the CD19+ ... blood and bone marrow Rituximab preferentially depletes B cells in peripheral blood marrow (PB) and reduces activated B cells in the PB and the bone marrow (BM) of rheumatoid arthritis (RA) patients...
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Báo cáo khoa học: "Lesions in the thymus and bone marrow in chicks with experimentally induced chicken infectious anemia disease" pot
... stained cells could only be detected in the thymus section of one bird in the experimental group on day 25 The first antigen specific staining in the bone marrow was recorded in one bird from the ... genetic constitution, nutritional state, and management conditions on the incidence of clinical manifestations and the severity of anemia in CIAV infections [1,7,9] The results of this study confirm ... 2) Lesions in the thymus and bone marrow in chicks with CIA 21 Fig (A) Abundant antigen-specific staining in the cortex and, to a lesser extent, in the medulla of the thymus section of an experimental...
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Báo cáo toán học: "MAINTENANCE HORMONAL TREATMENT IMPROVES PROGRESSION FREE SURVIVAL AFTER A FIRST LINE CHEMOTHERAPY IN PATIENTS WITH METASTATIC BREAST CANCER" docx
... type of first-line chemotherapy (anthracycline- and/ or taxane-containing regimen versus other); previous line of hormonotherapy administered in metastatic setting before the first-line chemotherapy ... Tables and list the significant predictive factors for the duration of PFS and OS after first-line chemotherapy Figures and show the patients PFS 102 and OS from the first line of chemotherapy ... type of hormonotherapy, type of chemotherapy, type of response achieved by treatment [5-12] The impact of some factors remains debatable, such the duration of treatment The optimal duration of chemotherapy...
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Báo cáo khoa học: "Outcomes of resection and non-resection strategies in management of patients with advanced colorectal cancer" doc
... presenting with malignant large bowel obstruction One of the concerns in managing patients with surgically incurable CRC without resection of the primary tumour is the risk of the patient presenting ... series the technique of stenting was introduced and developed in the unit during the study period and in the future may reduce the need for emergency surgical intervention and stoma formation in patients ... resection of their primary against non-resection intervention and supportive care on an intention to treat basis It has found that patients who undergo resection of their primary disease have the longest...
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Báo cáo y học: " Expression of Toll-like Receptor 9 in nose, peripheral blood and bone marrow during symptomatic allergic rhinitis" ppsx
... 8:17 epithelial cell line [30] In the present study, expression of TLR9 was found in the endothelial lining of small blood vessels This finding is in line with the detection of TLR9 mRNA in mouse ... represent one pathogenic mechanism explaining the worsening of allergic inflammation during airway infections Conclusion The widespread and rich expression of TLR9 in nasal epithelial cells and on nearly ... events bone marrow TLR9-FITC Figure of TLR9 in leukocytes from bone marrow, peripheral blood and nasal lavage fluid Expression Expression of TLR9 in leukocytes from bone marrow, peripheral blood and...
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báo cáo hóa học:" The effect of peer-led education on the life quality of mastectomy patients referred to breast cancer-clinics in Shiraz, Iran 2009" pot
... selected They were randomly assigned into experimental and control groups Of the experimental group one person discontinued leaving 49 patients in the experimental group and 50 in the control group The ... post and follow up intervention indicated the change process regarding fatigue and insomnia from the quality of life in relation to cancer Also, the side effects of systemic treatments in the control ... patients and carried on in two stages In the first stage and based on the patient’s physician’s opinion of the patients who were in stages I and II of the illness with at least five years remission...
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Báo cáo khoa học: "The effect of bioequivalent radiation dose on survival of patients with limited-stage small-cell lung cancer" pdf
... administered, followed by initiation of TRT within week after the start of the last cycle of induction chemotherapy, and then 2-4 cycles of adjuvant chemotherapy delivered within a week at the ... factor of timing and sequencing of TRT has little influence to our conclusion about radiation doseresponse because of the consistent chemotherapy administration in this population Conclusions In ... population and most of the patients were administered with TRT late This might be explained by the facts that: 1) only those patients who completed induction chemotherapy and TRT doses ≥ 50 Gy were included...
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báo cáo khoa học:" The effect of peer-led education on the life quality of mastectomy patients referred to breast cancer-clinics in Shiraz, Iran 2009" pot
... selected They were randomly assigned into experimental and control groups Of the experimental group one person discontinued leaving 49 patients in the experimental group and 50 in the control group The ... post and follow up intervention indicated the change process regarding fatigue and insomnia from the quality of life in relation to cancer Also, the side effects of systemic treatments in the control ... patients and carried on in two stages In the first stage and based on the patient’s physician’s opinion of the patients who were in stages I and II of the illness with at least five years remission...
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Báo cáo khoa học: "Effect of sedation with detomidine and butorphanol on pulmonary gas exchange in the horse" pps
... by the combination of detomidine and butorphanol was a further decrease in ventilation, with additional increase in PaCO This finding is probably an effect of butorphanol since the effect of the ... are limited reports on the respiratory effects of butorphanol alone or in combination with the a2-agonist detomidine in horses [5,11], but the effects of the combination on pulmonary gas exchange ... matching on hypoxic vasoconstriction, i.e redistribution of blood flow from regions of low ventilation to areas of higher ventilation, by pulmonary vasoconstriction, with only a small contribution...
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Báo cáo y học: " A comparison of olanzapine and risperidone on the risk of psychiatric hospitalization in the naturalistic treatment of patients with schizophrenia" ppsx
... drug, and (c) were not initiated on olanzapine and risperidone on the same day Importantly, the inclusion of patients who were continuously treated with the index drug during the year following initiation ... that therapy, even if therapy is discontinued [17] In contrast, the inclusion of patients who were continuously treated with the index drug during the study period permitted a more optimal and ... and continuing through the end of the year The mean cumulative days of hospitalization at the end of each of the 12 months post initiation indicated that the average number of hospitalization days...
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Báo cáo y học: "The impact of infliximab treatment on quality of life in patients with inflammatory rheumatic diseases" ppsx
... conducted in compliance with the Declaration of Helsinki, and all patients gave written informed consent to participate in the study The impact of treatment on the HRQoL of patients in the ATTRACT ... treatment with infliximab on the HRQoL of patients with these diseases Materials and methods This analysis included 1,987 patients from four clinical trials in which the safety and efficacy of infliximab ... patients, and through 54 weeks in patients with PsA and those with RA Discussion The burden of RA, PsA, and AS on patients, their caregivers, and society as a whole is significant Chronic inflammation...
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Báo cáo y học: "Enhanced glutamate, IP3 and cAMP activity in the cerebral cortex of Unilateral 6-hydroxydopamine induced Parkinson’s rats: Effect of 5-HT, GABA and bone marrow cell supplementation" ppsx
... μg/μl) and 10 μl of Bone marrow cell (BMC) (106 Cells/ml) suspension individually and in combination (combinational treatment) was infused into the right SNpc at a flow rate of 0.2 μl/min Nandhu ... radioligand on the X-axis and bound/free on the Y-axis The maximal binding is a measure of the total number of receptors present in the tissue and the equilibrium dissociation constant is the measure ... toxin, the probe was kept in the same position for a further for complete diffusion of the drug and then slowly retracted All the groups except Control group were infused with 6-OHDA and in control...
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báo cáo khoa học: "Persistence of TEL-AML1 fusion gene as minimal residual disease has no additive prognostic value in CD 10 positive B-acute lymphoblastic leukemia: a FISH study" doc
... expression of the hybrid protein that contains the functional domains of AML-I under the transcriptional control of the TEL promoter may be involved in oncogenic transformation [2,22] In this ... CMML, to the ABL tyrosine kinase in acute myeloid leukemia and ALL, and to the product of the MNI gene in myeloproliferative disorders AML-I is the DNA-binding subunit of the transcription factor ... transformation of cells belonging to a persistent preleukemic clone that was generated by TEL-AML1 fusion in utero and survived chemotherapy [27] The progress in treatment of ALL patients without conventional...
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Báo cáo y học: "Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice" pot
... 16 weeks in the B6 strain intriguing [29] The dysregulation of the calgranulins S100A8 and A9, in addition to CCL2 and IL8Rβ, warrants further investigation into a possible delayed inflammatory, ... corresponding sham alteration of genes under the higher level function of behavior and nervous system development and function These genes including D site of albumin promoter (albumin D-box) binding ... [9] In pulmonary diseases such as chronic obstructive pulmonary disease, chronic inflammation is considered central to the development of lung cancer In fact, the link between lung inflammation...
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Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... liver injury in conjunction with lipid-lowering agents; risk of bleeding complications in conjunction with antiplatelet agents, warfarin, niacin Induction of CYP3A4 increases metabolism of some anticoagulant ... pre-dialysis and 2–3 hrs following the post-dialysis dose There is a case report in which lithium levels were maintained in the therapeutic range by intraperitoneal administration of lithium during continuous ... carbamazepine, phenytoin, phenobarbital, and lamotrigine The triad of hypersensitivity includes fever, rash and internal organ involvement with onset of symptoms within to weeks of exposure The frequency...
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The management of patients with venous leg ulcers: Audit Protocol ppt
... in combination with signs of arterial impairment To assist in determining the type of ulcer the criterion used for examining the appearance of the ulcer is based on consensus statements, and literature ... undertaken Justification Lack of appropriate clinical assessment of patients with limb ulceration in the community has often led to long periods of ineffective and often inappropriate treatment ... non-members: £4.50 The management of patients with venous leg ulcers Contents Introduction Why an audit of patients with leg ulcers Background of national sentinel audit What is included in the...
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Risk Factors Affecting the Development of Tuberculosis Infection and Disease in Household Contacts of Patients with Pulmonary Tuberculosis pptx
... study the number of male patients was higher in the index cases, but the number of female patients was higher in contacts determined active disease In our opinion, the reason of this findings ... that the risk of infection increases in close contact with closer contact to the index case and more contact period In our study we evaluated tuberculosis risk only in household contacts of the index ... Factors Affecting the Development of Tuberculosis Infection and Disease in Household Contacts of Patients with Pulmonary Tuberculosis (such as uncle, grandfather, cousin) The definitions used for...
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báo cáo hóa học:" A MIF haplotype is associated with the outcome of patients with severe sepsis: a case control study" pdf
... healthy blood donors and patients with abdominal surgery but without signs of infection or inflammation Secondly, an evaluation of the association of the MIF polymorphisms with the survival of severe ... ≤60 years old and in patients with non-abdominal and non-pulmonary sepsis focus the association with poor outcome was pronounced Of note, the common observation in both groups was the decreased ... male and 48 female) 94 healthy blood donors and 183 patients after abdominal surgery without post-operative signs of infection or inflammation, without ICU admission and without case of death within...
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báo cáo hóa học:" Survivin gene levels in the peripheral blood of patients with gastric cancer independently predict survival" doc
... gene expression, have been used in the detection of tumor markers that indicate the presence of CTC in the blood [8] In the current analysis, we aimed to profiling the peripheral blood of 70 patents ... transcriptional abundance was in fact demonstrated only in patients with stage I to III disease (Figure 2) This finding might depends upon the low sample sizes of the single TNM stages (and the consequent ... predict patients' OS The hazard ratio (HR) associated with Survivin levels indicates the increase in risk of death for 100 fold increase in Survivin expression (Table 3) Since only these four independent...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25