the beginning was the end
Beginning at the End
... speed until she was pressed so hard into her seat she was sure she was leaving an imprint on the other side Again the movies got it wrong They showed the g-force lasting no more then about thirty ... Nicole was able to catch a glimpse of the pond in the back yard, which was free from weeds, probably more due to the weather then anything her grandparents had done to it Beyond the small pond was ... later the pilot came on and said that they were preparing for take off (What the hell was the twenty minutes prior for?) Finally the plane began to drive very slowly around the airport It was like...
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Báo cáo y học: "Genetic studies in osteoporosis - the end of the beginning" docx
... study The difference in the findings probably relates to the low coverage of ESR1 genetic variation in the GENOMOS study, which was estimated at only about 30% [54] The effect size of the fracture ... SOST, in the glucocorticoid receptor gene NR3C1 (in the top 500 BMD-associated SNPs overall), and in the vitamin D receptor gene and LRP5 (in the top 1,000 SNPs) It is therefore likely that other ... community BMD are summarized elsewhere [33] As was the general experience with these approaches in other complex genetic diseases, the signal-tonoise ratio was not sufficient to permit robust identification...
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Ho chi minh was the communist leader of north vietnam from the end of world war II until his death in 1969
... force of the independence movement, which became widely known as the Vietminh The Vietminh was able to exploit the chaos which descended upon Vietnam at the end of WW II to seize power, and the Democratic ... of the Vietnamese communists and of the independence movement in that country in the decades following WW II Ho was born Nguyen Tat Thanh in the Annam province, and was educated in Hué In the ... left in the West in the 1960s than for his actual contribution to political institutions or theory As his regime was successfully opposing the United States, and as the United States was the fount...
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The end of Angevin Brittany, 1186-1203
... reverse, the legend `+ NANTIS CIVI' or `+ REDONIS CIVI', with a simple cross in the ®eld Thus the name of the duke, as legend, was replaced by the place of minting, Nantes or Rennes Incidentally, these ... and thence returned to the royal principality.97 In the meantime, from around the beginning of August, some of the Manceau barons began to join King John Perhaps this was connected with the end ... were together at the time, and furthermore the latest date for both charters is 1195.54 If the sources con¯ict as to the place of Constance's capture, there is no evidence at all for the location,...
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Sincerity and the end of theodicy - three remarks on Levinas and Kant
... other than ontology, a thinking in which neither the being of the subject nor the being of the other is a primary concern and in which the other is never first encountered cognitively How, then, ... reluctant to endorse any discourse of ends or the end, will speak unapologetically of the end of theodicy ‘For an ethical sensibility the justification of the neighbour’s pain is the source ... as the description of suffering and that critique as the critique of theodicy, the announcing of the end of theodicy We are now in a position to say that what follows from the description is the...
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Tài liệu Color Atlas of Pharmacology (Part 26 and the end): Further Reading doc
... enantiomers, 62, 63 enantioselectivity, 62 endocytosis, 24 receptor- mediated, 26, 27 endoneural space, 206 endoparasites, 292 β-endorphin, 210, 211, 212 endothelium-derived relaxing factor (EDRF), ... some other commercially successful drugs are sold under more than 20 different brand labels The number of proprietary names, therefore, greatly exceeds the number of available drugs For the sake ... such as the name “diazepam” in the above example Use of Indexes The indexes are meant to help the reader: identify a commercial preparation for a given drug This information is found in the index...
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Tài liệu The life is at the end of the road doc
... The life is at the end of the road 2010 so sánh số với nước láng giềng Campuchia có 6%, Lào có 13% Thái Lan 9% Theo GS TS Lê Đình Quang, viện nghên cứu ... hứng gió rôto [m2] ρV3 [W/m2] Công suất trục rôto tính theo công thức: P = Think green and action green Page 2 The life is at the end of the road 2010 Một số lưu ý lắp đặt tua bin gió Nói ... thiết kế cho nhà rẻ b ó máy phát điện NLG tùy theo nhu cầu s dụng y n G sử Thin nk green an nd action gr reen Pa age 4 The life is at the end of the road 2010 Các bước để thiết kế hệ thống...
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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
... ER stress When the available acyl-CoAs are in excess, they are channeled towards TAG synthesis The main findings of the present investigation were the observations that TAG synthesis in liver ... Fig 3A, the relative amount of the antiapoptotic protein Bcl-2 was gradually increased in HepG2 cells during the initial 22 h of stearate treatment, but this increase was interrupted thereafter, ... thereafter, and the Bcl-2 concentration stabilized at a somewhat lower level On the other hand, the proapoptotic Bcl-2-like protein Bax was activated, as indicated by its translocation from the cytosolic...
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Tài liệu Báo cáo khoa học: The endogenous retinoid metabolite S-4-oxo-9-cis-13,14-dihydro-retinoic acid activates retinoic acid receptor signalling both in vitro and in vivo pdf
... restricted to the posterior half of the limb buds However, both retinoids induced the expression of shh in the anterior section As there is no endogenous expression of shh in the anterior tissue, the relative ... day before the start of each experiment The subsequent incubation with the indicated retinoids was then terminated at the indicated time points by washing with NaCl ⁄ Pi and lysis of the cells ... purity of the synthetic S-4o9cDH-RA used in the experiments, it can be excluded that the effects were falsified by any other active RA S-4o9cDH-RA was able to activate transcription in the presence...
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Tài liệu Báo cáo khoa học: Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen-related receptor c pptx
... Given that the roles of these residues definitely confirm each other, the difference in their significance might be attributable to the importance and ⁄ or necessity of the receipt of the phenol-hydroxyl ... ligand-binding pocket of the ERRc The proximity of each amino acid residue (within a ˚ distance of A) to BPA is shown in the boxes depicting the a-helices The portrait was originated from the X-ray crystal ... modulator, shares the same site for its binding to ERRc [20,22] BPA and 4-OHT elicited almost the same strong binding activity for the wild-type ERRc (Table 2, Fig 5) On the other hand, the concentrations...
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Tài liệu Báo cáo khoa học: Hu-K4 is a ubiquitously expressed type 2 transmembrane protein associated with the endoplasmic reticulum ppt
... to check whether the Hu-K4 antiserum recognizes endogenous Hu-K4 Indeed, a 55 kDa protein was identified by western blotting which was stained by the antiserum only in the absence of the peptides ... of the Hu-K4 gene (A) Position of the exons on the BAC clone CTC-492K19 (GenBank AC010271.8) The first and the last nucleotide of each exon are given The positions of the polyadenylation site, the ... any alternative splicing in the ORF or in the 3¢ untranslated region (UTR) To explain the splice variants observed in the Northern blot we analysed the 5¢-UTR of the available several dozen EST...
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Tài liệu Báo cáo khoa học: Physiological relevance of the endogenous mono(ADP-ribosyl)ation of cellular proteins doc
... is produced during the inflammatory response (and loses its antimicrobial activity) The relevance of these data also resides in the fact that this was the first demonstration of endogenous ADP-ribosylation ... disulfide bond with another conserved cysteine at 223 (C272 in mART1) at the C-terminus of the molecule, which stabilizes the folding of the a-helix-rich domain [11] C121 and C173 form the second disulfide ... essential for both activities The removal of the C-terminal basic domain decreases the transferase, but enhances the NADase activity The N- and C-terminal regions of ART1 are therefore required for...
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Tài liệu Báo cáo khoa học: "Is the End of Supervised Parsing in Sight?" pdf
... derivations, the probability of a tree is the sum of the probabilities of the derivations producing that tree The probability of a derivation is the product of the subtree probabilities The original ... iterations The training for U-DOP* consisted in the computation of the shortest derivations for the HC from which the subtrees and their relative frequencies were extracted We used the technique ... supervised parsers The NANC data was first split into sentences by means of a simple discriminitive model It was next p-o-s tagged with the the TnT tagger (Brants 2000) which was trained on the Penn Treebank...
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Tài liệu Báo cáo khoa học: The single tryptophan of the PsbQ protein of photosystem II is at the end of a 4-a-helical bundle domain docx
... possesses the same characteristics of the interior of the protein matrix The script a is the peak–peak distance between the maximum at %287 nm and the minimum at %283 nm, and the script b is the peak–peak ... all the possibilities for PsbQ, the four a-helix up/down bundle appeared to be the dominant topology, judging by the proportion (33% of all the cases) and the confidence level of the hits The ... microenvironment for the tryptophan residue, derived from the 3D model, is compatible with the fluorescence data Regarding the exposure of the tyrosine residues to the solvent, the described changes in the absorption...
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Tài liệu Báo cáo Y học: Presence and regulation of the endocannabinoid system in human dendritic cells potx
... was made in the same conditions using the CB1 polyclonal antibody and the CB2 polyclonal antibodies preabsorbed with the homologous antigens (4 lgÆmL)1 antibody solution) Then, the membrane was ... kDa (Fig 3B) The most abundant band was the one at 59 kDa, which was present in both human immature dendritic cells and in rat Ó FEBS 2002 The endocannabinoid system in human dendritic cells ... Taken together, these data show the presence of a complete endocannabinoid system in human dendritic cells Our findings, together with previous reports in the literature regarding other immune...
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Health and Work of the Elderly: Subjective Health Measures, Reporting Errors and the Endogenous Relationship between Health and Work doc
... (HRS) The first wave was fielded in the fall of 1993 and consists of 4727 households in which the head of the household (i.e., the main income earner) was between 43 and 63 years of age at the ... measures like the number of visits to a physician in the past 12 months, whether one was hospitalised in the past 12 months, whether one has experienced a chronic condition and the outcome of the Hopkins ... leisure Defined as the ratio of the growth in the present discounted value of the retirement income and the yearly gross wages See also the project by Gruber & Wise (1997) These numbers differ...
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The End of Need‐Based Student Financial Aid in Canada? ppt
... over $42 million. The other large student financial assistance expenditure in the province was the introduction (in 2007) of the Saskatchewan Graduate Tax Exemption. The Tax Exemption replaces the Graduate ... extended the freeze one year later (it announced the tuition reduction was permanent and would be fully funded in the future). The total cost of the two‐year freeze was $87 million. The ... students increased by about 20 percent from $1.05 billion to $1.25 billion. This is much lower than was the case nationally, where the average increase was 50 percent; on the other hand, since there were no tuition increases for Québec students, there were ...
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