tình hình sản xuất sách điện tử ở nước ta hiện nay
Basic immunology functions and disorders of the immune system
... of experimental data that emerge in the rapidly advancing field of immunology The choice of what is most important is based largely on what is most clearly established by experimentation, what ... undergraduate curricula and to take advantage of the new understanding of immunology We have tried to achieve several goals First, we have presented the most important principles governing the ... eliminated, thus returning the immune system to its basal resting state This return to a stable or steady state is called homeostasis It occurs because microbes provide essential stimuli for lymphocyte...
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Báo cáo y học: " Effector mechanisms of interleukin-17 in collagen-induced arthritis in the absence of interferon-γ and counteraction by interferon-γ" pot
... chemotactic protein-2 production J Leukoc Biol 2007, 81:1044-1053 29 Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) ... DE: Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease Cell 1996, 84:443-450 26 Matsuyama T, Kimura T, Kitagawa M, Pfeffer K, Kawakami T, Watanabe ... mouse embryos between 16 and 18 days of gestation, as described [28] Two times 105 MEF in a total volume of 300 μl Eagle's minimal essential medium (EMEM) containing 2% heat-inactivated FCS were seeded...
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Báo cáo y học: " Ageing, autoimmunity and arthritis: Senescence of the B cell compartment — implications for humoral immunity" pptx
... developmental stage to another In adult mice, development of B cells occurs in the BM in a series of steps that are definable by changes in cell surface expression of a variety of molecules (for detailed ... total of 662 BM specimens derived from 598 patients ranging in age from months to 92 years In that report the percentage of B lymphocyte precursors was determined as a function of age, and data ... presented some data that indicate that B lymphopoiesis declines with age but these trends were not statistically significant It should be noted, however, that this lack of statistical significance...
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Báo cáo y học: "Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis" ppsx
... substantially [82] On the other hand, cyclooxygenase (COX)2 is a key enzyme involved in the metabolism of arachidonic acid to prostaglandin H2, which is converted to biologically active prostaglandins ... Leung A, Stanworth D, Rademacher TW, Mizuochi T, Taniguchi T, Matsuta K, et al.: Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum ... Overexpression of oncostatin M in the mouse joints induced synovial pathology [61] and anti-oncostatin M treatment suppressed arthritis [62], except in one study in which human oncostatin M treatment...
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Báo cáo y học: "Tumor-infiltrating effector cells of α-galactosylceramide-induced antitumor immunity in metastatic liver tumor" pdf
... cells to determine the optimal conditions for mimicking liver metastasis of colorectal cancer in humans Liver metastasis of colorectal cancer usually consisted of discrete nodular lesions, rather ... symbols: TILs from Vehicle-treated mice Representative data of two experiments are shown metastasis to the liver Thus, we chose the Colon26 liver metastasis model in Balb/C mice for this study Although ... especially at the site of liver metastasis of colorectal cancer, we used a well-established murine colon cancer cell line, Colon26, in Balb/C mice We first tried to establish a C57BL/6 mice model...
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Báo cáo y học: "Lung epithelium as a sentinel and effector system in pneumonia – molecular mechanisms of pathogen " pdf
... in ventilated patients: a cohort study evaluating attributable mortality and hospital stay Am J Med 1993, 94:281-288 Lynch JPIII: Hospital-acquired pneumonia: risk factors, microbiology, and treatment ... Kagnoff MF, Eckmann L, Karin M: Nod2 mutation in Crohn's disease potentiates NFkappaB activity and IL-1beta processing Science 2005, 307:734-738 147 Watanabe T, Kitani A, Murray PJ, Strober W: NOD2 ... Toll-like receptors Nature 2002, 420:329-333 Honda K, Ohba Y, Yanai H, Negishi H, Mizutani T, Takaoka A, Taya C, Taniguchi T: Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I...
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A study of the mechanisms of immunity to pasteurella haemolytica infection
... PBS/Tween phosphate-buffered saline Tween P13 = containing 20 type parainfluenza PVP polyvinyl RBC red SC subcutaneous SE standard error SED standard error pyrrolidone blood S I = stimulation ... but does not produce reactions of species as classified and and attacks certain were adopted are (Cowan P facultatively fermentation, 1974) Steel, and anaerobic by sugars haemolytica diverse, ... experiments part some of collaboration this of of consequently in obtained Moredun this investigations with the tation in reported the experimental my colleagues Nevertheless, thesis carried out necessary,...
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Báo cáo y học: "Proteomic analysis of mechanisms of hypoxia-induced apoptosis in trophoblastic cells"
... designated Bag-1 Morpho/AS) was 5’- GCTGAGCCAGGCCCGCACTTGTTGA-3’ Morpholino oligomer 5’-CCTCTTACCTCAgTTACAATTTATA-3’ was used for the negative control JAR cells were seeded on 25 cm2 flasks and after ... shown in Table 4, such expression discrepancies between mRNA and the protein were detected for several other genes Table Slope of standard curve and correlation coefficient of representative genes ... semiquantitative RT-PCR was performed using an ABI 7500 RealTime PCR System Then standard curves were obtained, and the slope and correlation coefficient were calculated for each gene Table Comparison...
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Báo cáo y học: " Induction and effector phase of allergic lung inflammation is independent of CCL21/CCL19 and LT-beta
... dependent on chemoattractant receptor signaling J Immunol 2002; 169: 651-655 [42] Yamashita N, Tashimo H, Matsuo Y, Ishida H, Yoshiura K, Sato K, Yamashita N, Kakiuchi T, Ohta K Role of CCL21 and ... were maintained inside a whole-body plethysmograph (Buxco, Troy, NY) capable of measuring changes in airflow and trans-thoracic pressures and resistances [30] After establishing a stable baseline ... (lymphotoxin-beta knockout, or LTβ-KO [1]) or CCL21/CCL19 (plt mutant [2]) In initial studies, control, LTβ-KO, and plt mutant mice were immunized with OVA according to a protocol previously established...
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Study on the Photolytic Mechanisms of Red 141 Dye Wastewaters with an 185nm Vacuum-UV lamp
... concentration of the pollutant Table The pseudo-first order rate constants of Red 141 in VUV/H2O2 system pH kVUV/H2O2, -1 11 0.0916 0.0900 0.0884 0.0461 0.0335 CONCLUSION The results obtained have shown ... 141 and H2O2 concentrations Total sample volumes were kept below 2% of the total reactor volume Each run of the experiments in this work was replicated twice The standard deviations of the concentration ... kUV/N2 : pseudo-first order rate constant of pollutants in a VUV/N2 system In the oxygen-purging VUV system (VUV/O2), the contribution on the decomposition of reactants can be attributed to VUV direct...
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ISOTOPE HYDROGRAPH SEPARATION FOR MODELING OF RUNOFF MECHANISMS OF ATMOSPHERICALLY DERIVED CHEMICAL AND RADIOACTIVE POLLUTANTS
... metals in those water samples are then coupled with the isotope analysis Finally, the importance of the component originating from the precipitation (new water) in a carrier of hazardous metals ... Hourly precipitation (mm) Runoff and isotopic composition This paper deals with an observation for a precipitation event during Oct 22-23 of 2003 The amount of precipitation was 30 mm in total Figure ... the flow rate maintained a certain value (0.8 m3/s, 1400 of Oct 26) that was higher than the lowest value (0.5 m3/s) before the precipitation event Variations in the δD of precipitations and the...
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Mechanisms of Unstable Nitrite Inhibition of Aerobic Phosphate Uptake
... Water and Environment Technology, Vol 6, No.1, 2008 The obtained constants are listed in Table As shown in the table, the inhibition constant of Gourp-3 is the largest among them, since they have ... that they had nitrite reductase, but did not have nitrate reductase Regardless of inhibition mechanism (attack by nitric oxide or direct attack by nitrite), phosphate uptake inhibition is expectedly ... on inhibition mechanisms of phosphate uptake Table – Determined Inhibition Constants Figure shows the responses of PAOs to nitrite exposure with the obtained curves of modified non-competitive...
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Transmission mechanisms of monetary policy the evidence
... information about stance of monetary policy Monetary policy is effective in reviving economy even if short-term interest rates near zero Avoiding unanticipated fluctuations in price level important: rationale ... links • Only as good as the model it is based on Advantages and Disadvantages of Reduced Form Evidence • No restrictions imposed on the way monetary policy affects the economy • Correlation does ... the Importance of Money • Monetary policy does not matter at all • Three pieces of structural model evidence – Low interest rates during the Great Depression indicated expansionary monetary policy...
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Tài liệu Women''''s attitudes towards mechanisms of action of family planning methods: survey in primary health centres in Pamplona, Spain doc
... After Implantation Other * Total Not important Important Unsure Total Yes No Unsure Total Yes No Unsure Total Stop using Continue using Unsure Total Stop using Continue using Unsure Total 266 (46.3) ... divorced, widow) Total None Catholic Other (Protestant, Evangelist) Total Once a week or more Occasionally (≤ 1/mouth) Never Total Agree Disagree Don't know Total No Yes Total >2 Total Total 18–24 25–34 ... answers of women who stated they would not use methods acting between fertilization and implantation (stage 2) but that stated they would use methods acting after implantation (stage 3) as inconsistent...
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Tài liệu Báo cáo khoa học: Mechanisms of amyloid fibril formation – focus on domain-swapping doc
... slowly descending into a final funnel In certain cases of metastable states, the funnels can end in two or three minima We propose that such metastable states preceding fibril formation could well ... Hamada D, Tanaka T, Tartaglia GG, Pawar A, Vendruscolo M, Kawamura M, Tamura A, Tanaka N & Dobson CM (2009) Competition between folding, native-state dimerisation and amyloid aggregation in beta-lactoglobulin ... additives, such as metal ions or Fig Schematic representations of the chosen mechanisms (A) The TA model [98] In the TA model, in a rapid pre-equilibrium step, the soluble state (S) molecules that...
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Tài liệu Báo cáo khoa học: Survival mechanisms of pathogenic Mycobacterium tuberculosis H37Rv ppt
... transpositional mutagenesis techniques, 30 mutants of M tuberculosis were selected from a total screen of approximately 2500 mutants that showed reduced growth Seven of these mutants had insertion ... whereas phagosomes containing virulent M tuberculosis exhibit a persistent display of Rab5 [37] Recruitment and retention of tryptophan-aspartate containing coat protein (TACO) on phagosome wall ... promoter region of TACO gene Treatment with vitamin D3 and retinoic acid inhibits mycobacterial entry, as well as survival within macrophages [40] Moreover, TACO-mediated uptake of mycobacteria...
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Tài liệu Báo cáo khoa học: Mechanisms of obesity and related pathologies: Androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction pptx
... vicious hypogonadal state, the deposition of visceral fat ensues, contributing to central obesity In this pathological state, aromatase activity is increased, resulting in the metabolism of testosterone ... Clin Endocrinol Metab 71, 929–931 Chen RY, Wittert GA & Andrews GR (2006) Relative androgen deficiency in relation to obesity and metabolic status in older men Diabetes Obes Metab 8, 429–435 Mohr ... adipose tissue and metabolism in older men J Clin Endocrinol Metab 89, 4863–4872 130 Ginsberg HN & Huang LS (2000) The insulin resistance syndrome: impact on lipoprotein metabolism and atherothrombosis...
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Tài liệu Báo cáo khoa học: Reaction mechanisms of thiamin diphosphate enzymes: redox reactions pdf
... representation may occur (on the basis of structural considerations and previously available functional data [41]) The resultant model invokes active center residue His640 to be important for ... PFOR structure (Protein Data Bank code: 1kek) in transparent surface representation The ThDP radical and the three [Fe4S4] clusters are shown as sticks Edge-to-edge distances between all cofactors ... tenuously bonded acetyl moiety, as an unstable high-energy intermediate and, thus, its long lifetime, as demonstrated experimentally both in the crystalline phase and in solution, is seemingly...
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Tài liệu Báo cáo khoa học: Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters pdf
... acylamides (drugs: acetaminophen, phenacetin, utamide, isocarboxazid, lidocaine, butanilicaine; pesticide: acephate; herbicides and fungicides: acetochlor, propanil and butachlor) The AAA activity ... NATAc ([S]max = 0.5 mm) Moreover, NATAc up to mm did not inhibit the BuChE-catalysed hydrolysis of ASCh (0.0351 mm) or o-NTFNAC (23 mm) Therefore, it does not appear to bind Competition of NATAc ... acetanilides (o-NAC, o-NTFNAC) [26,35] In addition, BuChE does not hydrolyse m-nitroacetanilide [35], the fungicide propanil (m,p-dichlorocacetanilide) (present study) or drugs such as acetaminophen...
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Tài liệu Báo cáo khoa học: Models and mechanisms of O-O bond activation by cytochrome P450 A critical assessment of the potential role of multiple active intermediates in oxidative catalysis doc
... in drug metabolism Drug Metab Dispos 26, 11901193 Vaz, A.D.N (2001) Multiple oxidants in cytochrome P450catalyzed reactions: implications for drug metabolism Curr Drug Metab 2, 116 Watanabe, Y ... dismutase or catalase, implicating the involvement of a peroxo adduct in catalysis [243] In fact, reactivity was enhanced when H2O2 was the oxidant in place of reductant and air [243], and the putative ... that of the wild-type-catalyzed reaction [142], so that reasonable interpretation of the data seems difcult Evidence from comparative studies with non-P450 hemoproteins and metalloporphyrin models...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy