surgical treatment of germ cell tumors in the context of multimodal therapy
Report on the Regulation of Reproductive Cell Donation in the European Union potx
... ac) the spouse (cohabiting partner) of the sibling or ad) a close relative (except for a lineal kin and a sibling) of the spouse (cohabiting partner) or ae) the spouse (cohabiting partner) of the ... States to incorporate into their national legislation the principle of voluntary and unpaid donation It regards the paying of substantial fees to obtain human egg cells to be against the principles ... the sibling of the spouse (cohabiting partner) of the recipient and complies with the provisions set forth under Subsection (1); b) the donor offers the cells exclusively for the use of the recipient...
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Báo cáo sinh học: "Concomitant detection of IFNa signature and activated monocyte/dendritic cell precursors in the peripheral blood of IFNa-treated subjects at early times after repeated local cytokine treatments" doc
... for the therapy of HCV infection [22] and in the adjuvant melanoma setting [23], no study is currently available on the clinical use of this molecule administered as vaccine adjuvant In the present ... cytokine and not by the vaccine itself (Figure 3) Genes up-regulated in the PBMC of humans receiving IFNa are mainly involved in immune response-related functions In order to gain insights into the ... Consistency of IFNa signature in different in vivo and in vitro settings Heatmap of the 74 cDNA consistently up-regulated by IFNa in any of the in vivo and in vitro settings analyzed The lists of IFNa-up-regulated...
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báo cáo hóa học: " Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson''''s disease" pptx
... important role in the secondary activation of microglia, in the progression of the inflammatory response, and in the progressive loss of the dopaminergic neurons in MPTPinduced PD Therefore, COX-2 ... to the release of factors that initiate another cycle of oxidative and inflammatory insults The positive feed back loop may continue until the additional neuronal death (~50% of the remaining of ... which reduces the progression of the inflammatory response and reduces the perpetuation of the vicious circle instead of inhibiting microglial activation at the early stage when initial injury occurs...
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báo cáo hóa học:" Effects of GnRH agonist treatment on steroidogenesis and folliculogenesis in the ovary of cyclic mice" pot
... proteins in mice Increase in the expression of caspase-3 and cleaved PARP proteins noticed in the mice treated in vivo with GnRH-Ag also showed increase in the number of atretic follicles in the ... in the ovary was investigated following in vivo and in vitro administration of GnRH agonist in the intact cyclic mice Methods Animals All the experiments were conducted in accordance with principles ... Effect of in vitro treatment of different doses of GnRH-Ag on progesterone synthesis and western blot analyses of LH-R and 3b-HSD proteins in the ovaries of mice Progesterone synthesis by the ovary...
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báo cáo hóa học:" A retrospective analysis of clinicopathological and prognostic characteristics of ovarian tumors in the State of Espírito Santo, Brazil" ppt
... benign epithelial ovarian tumors (adenomas), tumors of low malignant potential (borderline tumors) , or malignant epithelial tumors (adenocarcinomas); being the latest the focus of the present ... 90% of the patients received a platinum-based regimen, being 70% of them in association with paclitaxel; ii) for adjuvant therapy: about 82.4% of the patients got the first choice adjuvant therapy ... 56.4% of the patients received platinum-based therapy As for platinum-based therapy responsiveness, 17.1% of the patients were resistant to the treatment, whereas 22.6% were susceptible to this therapy...
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báo cáo khoa học: "Surgical treatment of intracystic carcinoma of the breast" doc
... HER2(1+) ER(3+) PgR(3+) HER2(-) Medical treatment Endocrine therapy (TAM) Endocrine therapy (AI) Endocrine therapy (AI) Endocrine therapy (AI) Endocrine therapy (AI) Bt: Breast total resection, ... carcinoma of the breast: the role of radiation and endocrine therapy Am J Surg 2007; 194:497-500 Ohlinger R, Frese H, Schwesinger G, Schimming A, Köhler G Papilary intracystic carcinoma of the ... within the cystic wall was investigated as intracystic carcinoma of the breast Patients with intracystic carcinoma of the breast tend to be older than patients with other forms of breast cancer In...
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Báo cáo khoa học: "Identification of a novel germ-line mutation in the TP53 gene in a Mexican family with Li-Fraumeni syndrome" doc
... analysis of p53 mRNA and protein in this family in order to further elucidate the consequences of the mutation in the expression of p53 and the possible mechanism of carcinogenesis in carriers of the ... 133 (in exon 5), which at the DNA level is not affected in the case reported on here, making possible the existence of the Δ133p53 isoforms, which could participate in the carcinogenesis of the ... as a dominant negative, inactivating the p53 protein generated by the wildtype allele and blocking activities such as induction of apoptosis This could explain the pathogenicity of the insertion/duplication...
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Báo cáo khoa học: "Application of light microscopical and ultrastructural immunohistochemistry in the study of goblet cell carcinoid in the appendix" pdf
... immunohistochemistry Dispersed endocrine cells or endocrine cells in nests containing 3–4 goblet cells were observed in the submucous and muscle layer of the appendix The endocrine cells in appendiceal tumour ... with the hypothesis of the dual entodermal and neuroendocrine origin of goblet cell carcinoid [1] The ultrastructural investigation showed that in morphology the endocrine cells were from the ... endocrine cells in the muscle layer of the Figure caecum Serotonin-positive endocrine cells in the muscle layer of the caecum Magnification × 300 Discussion In the appendix goblet cell carcinoids appear...
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Báo cáo y học: "Short- and long-term effects of anti-CD20 treatment on B cell ontogeny in bone marrow of patients with rheumatoid arthritis" ppsx
... ascertain the low maturation status of the immature B cells a combination of CD38, CD24, and CD10 was used The frequency of expression of CD24/CD10 was clearly increased within the remaining B cell ... changes in the immunoglobulin expression of B cells following rituximab treatment Isolated bone marrow mononuclear cells were stained immunoglobulin expression of B cells following rituximab treatment ... all of the B cell populations decreased when analysing absolute numbers as shown in Table The majority of the surviving B cells was found within the IgD- populations This argues for a predominant...
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Báo cáo y học: " Surgical treatment of scoliosis in Smith-Magenis syndrome: a case report" pot
... CM was involved in the collection of data, and participated in writing the initial version of the manuscript All authors have read and approved the final manuscript Competing interests The authors ... was involved in the conception and design, analysis of the data, preparation of the manuscript, final approval of the version to be published AB did the data analysis, and the preparation of the ... well as a marked waist line asymmetry with prominence of the pelvis on the concavity of the lumbar curve There were no skin or soft tissue abnormalities overlying the spine The patient was a community...
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báo cáo khoa học:" Endoscopically assisted procedure for removal of a foreign body from the maxillary sinus and contemporary endodontic surgical treatment of the tooth" ppt
... hypertrophy of the inferior turbinates may explain the patient's previous symptoms of maxillary sinusitis including tenderness in the left infraorbital region and nasal stuffiness In this case ... the foreign body in the supero medial aspect of the maxillary sinus Intraoperative endoscopic view of the foreign body in the supero medial aspect of the maxillary sinus Figure Intraoperative endoscopic ... sinus Computed tomography scan (coronal plane) showing the foreignof the upper first the supero medial aspect of the maxillary Figure sinus and partial mucosal thickening of the sinus upon the...
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Báo cáo y học: " Identification of a novel linear B-cell epitope in the UL26 and UL26.5 proteins of Duck Enteritis Virus" doc
... date, there has been no study of the B -cell epitopes of DEV In this study, we first expressed the 360 amino acids in the C-terminus of the DEV UL26 protein (named UL26c), which contain the whole ... Formation of the herpesvirus capsid is the first step in viral morphogenesis The capsid of HSV-1 is found in the mature virions and in the nuclei of infected cells from which they originate There ... There are three distinct types of capsid, A-, B- and C-capsids, in infected cells [6] The B-capsids of HSV-1 contain a large amount of the scaffolding protein (the product of the UL26.5 gene),...
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Báo cáo y học: "Directed cell migration in the presence of obstacles" doc
... for large diffusion Of course the larger the range, the smaller the probability of the cell being captured The range is dictated by the magnitude of the fluctuations in the cell' s position, which ... probability of cell leaving the capture volume is less than the probability of cell entering it This qualitatively explains the increase in capture probability with increasing noise in the chemotaxis-dominated ... to the experiment introduced in the previ- C ous section The cells passing the closest to the obstacle are the ones initially close to the z-axis, i.e d is small For such cells the distance of...
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Asymmetric cell division in the regulation of neural stem cell self renewel in drosophila melanogaster
... understanding of cancer These findings offer new perspective to study the control of cell growth and cell- cycle progression, and to re-examine the initiating events in tumor formation The fact ... one of the hallmarks of cancer There is an increasing body of evidence to suggest that spindle orientation plays a vital role in suppressing stem -cell overgrowth A case in point is the effects of ... Strikingly, the increase in activity of these cell cycle proteins (at prometaphase and metaphase) coincides with the timing of asymmetric protein localization during neuroblast divisions, lending...
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Novel mechanisms of programmed cell death in the protozoan parasite blastocystis
... homologs of mammalian molecules involved in cell death signaling are missing in the protozoa and the molecular architecture of PCD in protozoan parasites therefore remains puzzling The kinetoplastid ... Objectives of the present study Despite increasing number of studies describing the cytochemical features of PCD in protozoan parasites, knowledge of the mechanism and molecular mediators of PCD in these ... Wajant, 2002) In the intrinsic pathway, various extracellular and intracellular stresses activate one or more members of the BH3-only protein family The activation of BH3-only protein above a threshold...
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Báo cáo y học: "Surgical Treatment of Depressed Scar: A Simple Technique"
... entire scar again Therefore, with this objective in mind, in the presence of adherent scars, after having infiltrated the whole area with a solution of Lidocaine 0.5% and Epinephrine 1:200,000 ... FMA: participated in the surgical treatment and in the follow-up of this patient MM: participated in the design of this case study and in the follow-up of this patient ADI: revised the literature ... attach the skin to the floor below Infact, the use of the stitches in depth is performed in order to prevent that the adhesion can recreate again: this relapse could promote the formation of a...
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Organizing pairwork and groupwork in the context of high school classrooms at pham van nghi upper secondary school, nam dinh province: A case study
... each other rather than learn the mistakes One of the main points of having learners speak to each other is to help them increase their confidence and reduce the anxiety that is often found in a ... effect The language proficiency of the the success of a pair teacher work and group The teacher’s ability of organizing The hardship of the students work ? The cooperation of the students The language ... found the work of the students in group of three was ineffective In the time of five minutes they only discuss some information about that place.They must collect information from the other groups...
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The UN Model Double Taxation Convention in the context of Financing for Sustainable Development
... prevent having income from cross-border investment taxed twice (i.e both in the host country of the Why countries need Double Tax Treaties? investment and in the residence country of the investor), ... taxpayers against double taxation of the same income; - promote the flow of international trade and investment; - provide a framework of legal and fiscal certainty to investors; - prevent discrimination ... Take into account recent developments in the area of international tax policies of both developing and developed countries • Seek further consistency with the OECD Model, where in line with the...
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A STUDY ON THE USE OF CLASSROOM DISCIPLINE AS MOTIVATION FOR SECOND LANGUAGE ACQUISITION IN THE CONTEXT OF ENGLISH LANGUAGE TEAC
... Objectives of the survey: The questions in the survey questionnaire were divided into three main areas of study, including: the causes of disruptive behaviours, the reactions of discipline and the codes ... go further to explain discipline problems in the light of interpersonal relationships between teachers and learners In this exhaustive research, they investigate the different theories of interpersonal ... behaviours as one way of defining discipline His main concerns lie in the reasons for discipline and the trends towards the emergence of the disruptive behaviors: ‘At some stage of their lives, all...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25