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strategies radiotherapy and targeted radionuclide therapy approaches for the treatment of multiple myeloma

design, synthesis, and biological evaluation of new anti-cancer nitrogen-containing combretastatins and novel cysteine protease inhibitors for the treatment of chagas

design, synthesis, and biological evaluation of new anti-cancer nitrogen-containing combretastatins and novel cysteine protease inhibitors for the treatment of chagas

Tiến sĩ

... Cook and Andrea Johnson for all their help during these years My special gratitude to Mrs Beth Walker and other staff members at the office of the International Student and Scholar Services for ... cancer The treatment that is chosen depends on many different factors including the type of cancer, extent of the disease, rate of progression, condition of the patient and response to the therapy; ... because they are gaps in the cell cycle that come between the time of chromosome division and the time of chromosome replication The S stands for synthesis of DNA, and finally the division phase is...
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Báo cáo khoa học:

Báo cáo khoa học: "Prior surgical intervention and tumor size impact clinical outcome after precision radiotherapy for the treatment of optic nerve sheath meningiomas (ONSM)" docx

Báo cáo khoa học

... returned in 32 out of the 40 patients (80%) The median age at the time of radiotherapy was 44 years (range 17-83 years) The tumor manifestation was on the right eye in 16 patients and on the left eye ... as the gross tumor volume (GTV), adding 1-2 mm safety margin for the planning target volume (PTV) The median PTV was 9.2 ml Radiotherapy planning for FSRT was performed using the Voxelplan ® software ... have reported their clinical results of precision radiotherapy for the treatment of ONSM Figure Correlation of PTV-size and visual outcome Patients with smaller treatment volumes were more likely...
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Báo cáo khoa học:

Báo cáo khoa học: " Optimal organ-sparing intensity-modulated radiation therapy (IMRT) regimen for the treatment of locally advanced anal canal carcinoma: a comparison of conventional and IMRT plans" ppsx

Báo cáo khoa học

... Pierart M: Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a Page 10 of 11 (page number not for citation purposes) ... V20 of 59% and V10 of 73% It is possible that sparing of the femoral heads and/ or other organs comes at the cost of increasing dose to the iliac crests The results of our study reinforce the ... Contribution of conformal therapy in the treatment of anal canal carcinoma http://www.ro-journal.com/content/2/1/41 24 25 26 27 28 29 with combined chemotherapy and radiotherapy: results of a phase...
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Báo cáo y học:

Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"

Y học thưởng thức

... system, in the distal segment of the tubule Inhibition of glucose reabsorption in the kidney, mediated by the SGLT cotransport system, represents a promising therapeutic target for the control of hyperglycemia ... hydrolysis-resistant, synthetic S-analogs of natural O-glucosides involved in the biosynthesis of chrysomelidial and salicin These substances are synthesized and secreted as part of a defense mechanism ... larvae of beetles (Chrysomelidae) Their synthesis has been previously described [31-33] For the purpose of the present study the thioglycosides used were selected and grouped based on their differences...
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Tài liệu Bevacizumab and cetuximab for the treatment of metastatic colorectal cancer docx

Tài liệu Bevacizumab and cetuximab for the treatment of metastatic colorectal cancer docx

Sức khỏe giới tính

... from data in the RCT The survival of patients receiving ASC/BSC was calculated from the survival of the patients in the cetuximab monotherapy arm of the RCT The data from the monotherapy arm NICE ... evidence from the bevacizumab studies and noted that the age of the population in the largest study was lower than the age of patients normally receiving chemotherapy in England and Wales However, ... guide for healthcare professionals Information for people with metastatic colorectal cancer and their carers (‘Understanding NICE guidance’) Details of all the evidence that was looked at and other...
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Tài liệu Carrots, Sticks, and Promises: A Conceptual Framework for the Management of Public Health and Social Issue Behaviors docx

Tài liệu Carrots, Sticks, and Promises: A Conceptual Framework for the Management of Public Health and Social Issue Behaviors docx

Tiếp thị - Bán hàng

... and accommodate the target's MOAs and the trade-off of free choice and externalities The potential for success of the three sets of tools is derived from the target's assessment of the "risk premium" ... (2) the target's MOA; and (3) the use of the tools of education, marketing, and law Figure I shows the eight segments of any market that result from the combinations of the presence or absence of ... followed if the target cannot discern the reward in doing so Dickson (1992) discusses the invisible hand of competition that constrains the self-interest of the firm and forces the firm to serve the...
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The importance of project management in small- and medium-sized enterprises (SMEs) for the development of new products through E-collaboration docx

The importance of project management in small- and medium-sized enterprises (SMEs) for the development of new products through E-collaboration docx

Quản lý dự án

... concept (either for the company or for the customer) It includes all activities from the development of an idea or a concept for a product, to the realization of the product during the production ... to h The participants were given an explanation regarding the purpose of the feedback, the purpose of the conceptual model, some background of the research that lead to the development of the ... management is the manner of implementation, of expertise, paraphernalia, knowledge and modus operandi to an extensive range of activities for the fulfillment of prerequisite of the specific project”...
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Báo cáo khoa học: Re-evaluation of intramolecular long-range electron transfer between tyrosine and tryptophan in lysozymes Evidence for the participation of other residues doc

Báo cáo khoa học: Re-evaluation of intramolecular long-range electron transfer between tyrosine and tryptophan in lysozymes Evidence for the participation of other residues doc

Báo cáo khoa học

... achieved by calculation of the portion of the total area under the curve occupied by the dimers peak The obtained value was divided by two MALDI-TOF MS was performed at The Institute of Nuclear Physics, ... TyrOÆ yields in the lysozymes from the magnitudes of the absorbance changes at 510 and 410 nm and the assumption that the extinction coefficients of the protein bound radicals and those measured ... compared to the 90% loss of Trp after the completion of this reaction We confirm that the process is nonstoichiometric and that the amount of LRET depends on the primary structure of the protein...
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Pelvic floor muscle training and adjunctive therapies for the treatment of stress urinary incontinence in women: a systematic review doc

Pelvic floor muscle training and adjunctive therapies for the treatment of stress urinary incontinence in women: a systematic review doc

Sức khỏe phụ nữ

... outcome of physical therapy? What is the optimal period of treatment and number of treatments? What is the effectiveness of physical therapy in clinical practice settings and can the findings in the ... evidence for the optimal period of treatment and number of treatments? We found evidence for the efficacy of shorter treatment protocols than the 4–6 months recommended by the ICS The basis of the ... the differences in outcome The expertise of health professionals may vary and also the quantity and quality of the educational information about the condition and PFM function The impact of these...
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SYNTHESIZE AND INVESTIGATE THE CATALYTIC ACTIVITY OF THREE-WAY CATALYSTS BASED ON MIXED METAL OXIDES FOR THE TREATMENT OF EXHAUST GASES FROM INTERNAL COMBUSTION ENGINE

SYNTHESIZE AND INVESTIGATE THE CATALYTIC ACTIVITY OF THREE-WAY CATALYSTS BASED ON MIXED METAL OXIDES FOR THE TREATMENT OF EXHAUST GASES FROM INTERNAL COMBUSTION ENGINE

Tiến sĩ

... choice and loading of the NM is a compromise between the required efficiency of the converter and the market price of the NM However, the application of noble metals for the treatment of exhaust ... are formed in adsorption of reactant molecules on the semi-conducting surface; the formation of these is a function of the electronic properties of the solid, and the structure and kind of bonds ... begins with the adsorption of CO and O2 on the Nguyen The Tien 29 Synthesize and investigate the catalytic activity of three-way catalysts based on mixed metal oxides for the treatment of exhaust...
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báo cáo hóa học:

báo cáo hóa học:" Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer" pdf

Hóa học - Dầu khí

... overall survival of treated animals (Figure 6D) These results confirm the anti-tumor activity of anti-VLC therapy, as observed by others, and further support the use of anti-CD52 therapy in humans ... anti-CD52 therapy was initiated one week after the injection of tumor cells Anti-CD52 immunotoxin therapy lead to a delay in the accumulation of tumor-associated ascites and an improvement in the median ... absence of complement; (1) In the presence of Alemtuzumab and heat inactivated sera, the majority of VLC are viable Annexin V (-) and PI (-) cells In contrast, in the presence of Alemtuzumab and...
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báo cáo hóa học:

báo cáo hóa học:" Two levels above and one level below pedicle screw fixation for the treatment of unstable thoracolumbar fracture with partial or intact neurology" pot

Hóa học - Dầu khí

... bending of the hardware, and segmental kyphosis after a caudad screw in the lumbar construct broke And they noted that untreated anterior instability, and pre-stressing of the screws when the rods ... drafting the manuscript and designing of data and revising it critically, KCN has contributed in acquisition of data and analysis and interpretation of data, and JHY has contributed in acquisition and ... through the rod pusher to bring the vertebra back to the rod Gentle distraction at the level of the fracture followed, restoring tension to the posterior longitudinal ligament (ligamentotaxis) and thereby,...
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Báo cáo hóa học:

Báo cáo hóa học: " A quantum dots and superparamagnetic nanoparticle-based method for the detection of HPV DNA" ppt

Hóa học - Dầu khí

... Page of predenatured at 95°C for 10 min, then 55°C for 30 The particles coupled with streptavidin were added into the hybridization mixtures and incubated at 37°C for 10 and enriched in the bottom ... the cutoff value of QDs and superparamagnetic nanoparticle-based hybridization The detection procedure was described in detail in the next section (Figure 1) The cutoff value was defined as the ... validate our hybridization assay on the basis of the cutoff value Detection of HPV-16 with QDs and superparamagnetic nanoparticle-based hybridization The rationale of QDs and superparamagnetic nanoparticle-based...
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Báo cáo hóa học:

Báo cáo hóa học: " Research Article Development of Long-Range and High-Speed Wireless LAN for the Transmission of Telemedicine from Disaster Areas" pdf

Báo cáo khoa học

... Cordova, P Boets, and L Van Biesen, “Analysis and applications of Wi-MAX standard: forecasting the trends” J Crouse, M D’alessandro, and F Lengerich, “WiMAX and the future of wireless technology,” ... station then forwards these packets to the Kiyomizu relay station In Kiyomizu relay station, the received video image and sound packets are forwarded to the NPGITC At NPGITC, these image and sound ... Hz The first item in (4) (a)–(f) shows compression rate for video signal CBR and VBR stand for constant bit rate and variable bit rate, respectively SIF stands for source input format HalfD1 stands...
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Báo cáo y học:

Báo cáo y học: "A 12 Week, Open Label, Phase I/IIa Study Using Apatone® for the Treatment of Prostate Cancer Patients Who Have Failed Standard Therapy" pps

Báo cáo khoa học

... Standard therapy was defined to include radical prostatectomy, radiotherapy and hormonal ablation We did not include docetaxol chemotherapy in our inclusion criteria for failure of standard therapy ... with knots at -60 weeks, the start of Apatone therapy and end of therapy ( ) indicate where patients went off Apatone or started alternative therapy Table PSA Velocity and Doubling Time in Months ... seen before treatment once treatment ended (Fig 1a and 1b) Thirteen of the 17 patients had a successful outcome; a decrease in PSAV and a lengthening of PSDT (Table 2) The probability of 13/17...
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Báo cáo y học:

Báo cáo y học: " Pregnancy and delivery while receiving vagus nerve stimulation for the treatment of major depression: a case report" pot

Báo cáo khoa học

... contraindication for enrollment in the VNS studies of patients with TRD, there have been no studies of the use of VNS therapy among pregnant patients A report of eight pregnancies in patients receiving VNS therapy ... Inc., collected the data for this pilot study and encouraged the authors to submit this case report to help increase the understanding of VNS therapy and pregnancy References Andersson L, Sundstrom-Poromaa ... substantial improvement after the initiation of VNS therapy Figure The patient's score on the CGI-S scale also indicated a substantial improvement after the initiation of VNS therapy Pregnancy from...
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Báo cáo y học:

Báo cáo y học: "Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action" pps

Báo cáo khoa học

... [70] and IL-1αinduced PGE2 production [71] in a dose- and MW-dependent manner; the higher the MW and concentration, the more potent the inhibition Intra-articular injection of HA in the temporomandibular ... levels of prostaglandin F2α, 6-keto-prostaglandin F1α, and leukotriene C4 [72] In synovial fluid from the knees of patients with OA and RA, intra-articular HA reduced the levels of PGE2 [73,74] and ... In the synovium of HA-treated knees, the number and aggregation of synoviocytes decreased, and both treatments reduced the number of inflammatory cells, including macrophages, lymphocytes, and...
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báo cáo khoa học:

báo cáo khoa học: "Surgical perspectives from a prospective, nonrandomized, multicenter study of breast conserving surgery and adjuvant electronic brachytherapy for the treatment of breast cancer" pps

Báo cáo khoa học

... during the 5-day treatment period Patient compliance with the treatment regimen was excellent Patients expressed satisfaction with the conduct of the study as well as the delivery of the radiotherapy ... Group (EBCTCG): Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomized trials Lancet ... comparison of MammoSite high-dose-rate brachytherapy and Xoft Axxent® electronic brachytherapy Brachytherapy 2007, 6:164-168 19 Dickler A: Xoft Axxent® electronic brachytherapy: a new device for delivering...
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Báo cáo khoa học:

Báo cáo khoa học: "Feasibility study of volumetric modulated arc therapy for the treatment of retroperitoneal sarcomas" pdf

Báo cáo khoa học

... Otto K: Volumetric modulated arc therapy for delivery of prostate radiotherapy: comparison with intensity-modulated radiotherapy and three-dimensional conformal radiotherapy Int J Radiat Oncol Biol ... 5% and 95% of the PTV) For all patients DVH for OAR (bowel, bowel excluding PTV, kidneys and spinal cord) were calculated and reported A set of V x values and Dmean was therefore reported The ... doses of 1.2% and 1.7% in the cylindrical phantom Percentage of points meeting the criteria of 3%-3 mm for the gamma index was 98.3% and 95.7% for both patients Figure and shows examples of dose...
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346 Biomass – Detection, Production and Usage live yeast biomass for the leavening of bread docx

346 Biomass – Detection, Production and Usage live yeast biomass for the leavening of bread docx

Tài liệu khác

... phenoxypropylamine-type inhibitor for sterol biosynthesis was added to the medium The isolation and characteristic of the carotenogenic genes of yeasts facilitates the study of the effect of their overexpression ... accounts for 60 to 75% of the total costs of the biodiesel Thus, the cost of lipid production was influenced strongly by the cost of medium nutrients (50%) needed for cultivation of cells and the ... However, the intensity and protocol of illumination varies with the microorganism Temperature is another important factor affecting the performance of cells and product formation The effect of temperature...
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