stimulation inflammation regulator of adaptive and innate immunity
Báo cáo y học: "Between adaptive and innate immunity: TLR4-mediated perforin production by CD28null T-helper cells in ankylosing spondylitis" pptx
... of attachment and invasion into the cartilage and bone [18] The TLR2-mediated stimulation of synovial fibroblasts with bacterial components promotes the release of proinflammatory cytokines and ... expression of T-cell receptor (TCR) and PRRs on the cell surface further supports the role of CD4+CD28null T cells as an immunological link between the adaptive and the innate defence system, and is ... 0.7 ± 1% of CD4+CD28+ T cells in AS, on 8.8 ± 15.7% of CD4+CD28null T cells versus 1.0 ± 2.3% of CD4+CD28+ T cells in PsA, and on 11.3 ± 17.2% of CD4+CD28null T cells versus 0.6 ± 0.6% of CD4+CD28+...
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Báo cáo y học: "Stimulation dependent induction of fear and depression in deep brain stimulation: a case report" docx
... improvement of mood which correlated with HMDS and BDI scoring (Table 1) With the patient’s consent, we tested the reproducibility of the induction of depression and found acute onset of depression and ... the mean diameter of the STN of 2.5-2.5 mm and the variety of side effects, a direct attribution of all of these side effects to one particular spot is difficult Also the authors of this article ... influence of DBS on mood [9-11] This is the first report of acute stimulation- dependent induction of fear Here the electrode position was mm caudal of the calculated target point for the STN and, ...
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Báo cáo y học: "Interactions between human immunodeficiency virus (HIV)-1 Vpr expression and innate immunity influence neurovirulence." doc
... V: HIV-1 Vpr: mechanisms of G2 arrest and apoptosis Exp Mol Pathol 2008, 85:2-10 16 Moon HS, Yang JS: Role of HIV Vpr as a regulator of apoptosis and an effector on bystander cells Mol Cells 2006, ... pixels) were acquired at a scanning time of s per frame Selected regions of interest were drawn around distinct cell bodies and traces of time course of change of fluorescence intensity were generated ... Department of Pharmacology, Faculty of Science, Mahidol University, Rama IV road, Bangkok, 10400, Thailand 6Department of Neurology and Pathology, Johns Hopkins University School of Medicine,...
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Design of adaptive and hybrid energy QOS aware heterogeneous multiprocessor scheduling strategies for embedded systems
... in a very high rate of charge lock-up and a large αL , and vice versa A lower value of β also indicates a low rate of recovery of αL β is measured in sec−1 A typical value of β for a lithium ... constraints and poses Figure 2.1: BSN employed to monitor health of an athlete unique challenges One of it is the choice of the energy pack Being mobile and unobtrusive the energy pack of choice ... developers and found to be accurate to within ±3% of actual charge and lifetime measurements of lithium-ion batteries Lithium-Ion is the battery chemistry of choice for powering the constituent PEs of...
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Báo cáo khoa học: Apolipoproteins A-I and A-II are potentially important effectors of innate immunity in the teleost fish Cyprinus carpio pot
... 0006 and AUS 0005 that supported the research visits of M.I.C to the Gatty Marine Laboratory University of St Andrews, Scotland, UK and of V.J.S to the Institute of Biochemistry, Faculty of Sciences, ... intact apolipoproteins and lysozyme Ó FEBS 2004 ApoA-I and apoA-II in innate immunity of the carp (Eur J Biochem 271) 2989 Once the antimicrobial mechanism of action of apolipoproteins has been ... ApoA-I and apoA-II in innate immunity of the carp (Eur J Biochem 271) 2987 Fig Synergy of the apoA-I synthetic peptide with lysozyme (A) Bacterial growth in the presence of different combinations of...
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Báo cáo y học: "The role of leptin in innate and adaptive immune responses" doc
... role of leptin in immune responses and inflammation has lately become increasingly evident Altered leptin production during infection and inflammation strongly suggests that leptin is a part of ... expression of the suppressor -of- cytokine signaling (SOCS)-3, which inhibits STAT signaling [30] In addition, stimulation of leptin receptor triggers activation of phosphatidylinositol 3-kinase (PI3K) and ... altering production of proinflammatory and anti-inflammatory cytokines and may also affect cytokine signaling by a variety of mechanisms, including induction of SOCS-3 [33] to express and secrete leptin,...
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Tài liệu Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia pptx
... switch and alters the expression of the two nuclear genome coded isoforms of CytOX V [10,32] The regulation of genes CytOX5a and CytOX5b, coding for the two isofoms Va and Vb, parallels that of genes ... different stages of adaptive response to hypoxia Based on the results of our study and those of Schumacker, it is reasonable to conclude that the effects of hypoxia on CytOX gene expression and its activity ... group of cells that were exposed to hypoxic conditions for 6–12 h were re-exposed to normoxic conditions for an additional period of h Collection of cells and fractionation At the end of the...
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Báo cáo khoa học: Adipophilin increases triglyceride storage in human macrophages by stimulation of biosynthesis and inhibition of b-oxidation doc
... multiplicity of infection values (m.o.i.) of 100 and 500, adipophilin mRNA was increased 14 ± 0.8- and 39 ± 7.8-fold, respectively, and adipophilin protein was increased 6.5 ± 1.7- and 38 ... in adipophilin-overexpressing and control cells was similar and unaffected by addition of the ACAT-1 inhibitor CAY10486 The absolute amounts and fold stimulation of TG accumulation in palmitate-loaded, ... plasmids and pAdEASY-1 [36] and plaque purified High titre stocks of Ad.CMV.adipophilin and Ad.CMV.GFP (2.7 · 1012 and 8.5 · 1012 viral particlesÆmL)1, respectively) were produced in 293 cells and...
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Báo cáo khoa học: Intermittent hypoxia is a key regulator of cancer cell and endothelial cell interplay in tumours pot
... [18,22,23,35] The use of these techniques and their combination allow a better understanding of spatial and temporal changes in hypoxia in solid tumours, and also allow the linkage of these changes ... succession of short hypoxia and reoxygenation phases, typical of intermittent hypoxia, also stabilize HIF-1a and activate HIF-1? In the absence of oxygen, HIF-1a is rapidly stabilized, and short, ... observed after the repetition of cycles of of hypoxia followed by of reoxygenation for weeks [101] Moreover, in vitro, an increase in endothelial cell migration and formation of tubes was also reported...
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adaptive motion of animals and machines - hiroshi kimura et al (eds)
... understand the principles of animals’ remarkable ability for adaptive motion and to transfer such abilities to a robot Up to now, mechanisms for generation and control of stereotyped motions and adaptive ... (Editors) Adaptive Motion of Animals and Machines With 241 Figures ABC Hiroshi Kimura Graduate School of Information Systems University of Electro-Communications 1-5-1 Chofu-ga-oka, Chofu, Tokyo ... take up and push off Furthermore the amplitude and the time course of the angular velocity is rather similar in the different tasks Almost independent of the load and thus of reaction force and muscle...
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Báo cáo hóa học: "Programmed cell death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8+ T cell immunity" doc
... properties of nonreplicating vectors and biological response modifiers by direct intra-nodal administration of plasmid and peptide [19,41] We showed that the sequence and the route of administration of ... treatment of diseases such as HIV, other microbes and cancer [11,22-37] In addition, such protocols offer a more Page of 11 practical alternative for active immunotherapy of cancer and other ... α-fetoprotein VSV – expressing Gag of HIV Induction of robust CTL immunity in mouse Immunity against Hsp67, 70, Apa in calves Protective immunity against SHIV in primates Protective immunity against SHIV...
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Báo cáo sinh học: "Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells" doc
... regulation of differentiation, cell growth, and responses to cytokines, chemokines and stress The core element in MAPK signaling consists of a module of kinases, named MKKK, MKK, and MAPK, which ... Figure Involvement of p38 MAPK in ethanol induction of ISRE transcription and Stat1 serine phosphorylation Involvement of p38 MAPK in ethanol induction of ISRE transcription and Stat1 serine phosphorylation ... effect of CYP2E1 and ADH inhibition on ethanol activation of the ISRE Huh7 cells in 96 well plates were transfected in triplicate with 50 ηg of ISRE-luc and 12 hours later, were treated with mM of...
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Báo cáo hóa học: " Feasibility of the adaptive and automatic presentation of tasks (ADAPT) system for rehabilitation of upper extremity function poststroke" pptx
... practice of real-world tasks; and 3) training should be individualized by adaptively changing the number of trials and difficulty of each task practiced according to the evolving skill level of the ... a number of real-world functional tasks [56] ADAPT can accommodate an expanding number of such tasks, and it allows the implementation of performance-based adaptive task scheduling and task difficulty ... training of different grasps (power, overhand, and pinch) and arm movements Thus, like other automated rehabilitation devices, ADAPT allows both delivery of large intensity of training and longitudinal...
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báo cáo hóa học: " Neuronal oxidative damage and dendritic degeneration following activation of CD14-dependent innate immune response in vivo" doc
... rapidly and efficiently converted to multiple PGs or thromboxane A2, each of which are potent activators of a large family of G protein-coupled receptors [5] The combination of these initial and ... brain, no detectable adaptive immune response, and no loss of pyramidal neurons from hippocampal sector CA1 Page of (page number not for citation purposes) Journal of Neuroinflammation 2004, 1:20 ... Attack and O Insertion OH OH OH OH COOH COOH OH OH F 2-IsoP F -NeuroP Diagram2showing the formation of F2-IsoPs and F4-NeuroPs Figure Diagram showing the formation of F2-IsoPs and F4-NeuroPs Page of...
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báo cáo hóa học: " Apolipoprotein E isoform-dependent dendritic recovery of hippocampal neurons following activation of innate immunity" pot
... LaserSharp software (BioRad) Five or more MAP2-stained neurons were randomly selected and dendrite length and branch number measured with Neurolucida SZM and CS were blinded to APOE of the astroctyes ... cultures of wt cerebral neurons with CM from primary cultures of TR APOE2 or TR APOE4 Page of (page number not for citation purposes) Journal of Neuroinflammation 2006, 3:21 http://www.jneuroinflammation.com/content/3/1/21 ... Attenuation of chronic neuroinflammation by a nitric oxide-releasing derivative of the antioxidant ferulic acid J Neurochem 2004, 89:484-493 Imler JL, Hoffmann JA: Toll receptors in innate immunity...
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báo cáo hóa học: " Innate Immunity in multiple sclerosis white matter lesions: expression of natural cytotoxicity triggering receptor 1 (NCR1)" pptx
... control patients, females and males, were free of any evidence of known neurological disease, and had an average age at death of 47 (range 26-60) Further details of control and MS cases can be found ... Cambridge, UK) and LabWorks™ image capture and analysis software ImageJ software [28] was used to conduct as semi-quantitative analysis of expression Mean voxel intensity of bands was used to ... comparison Homogeneity of variance was assessed using Ftest Microsoft Office Excel 2010 (Microsoft UK Headquaters, Reading, UK) and GraphPad Prism 5.01 (GraphPad Software, La Jolla, CA) software packages...
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báo cáo hóa học:"Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells" potx
... regulation of differentiation, cell growth, and responses to cytokines, chemokines and stress The core element in MAPK signaling consists of a module of kinases, named MKKK, MKK, and MAPK, which ... Figure Involvement of p38 MAPK in ethanol induction of ISRE transcription and Stat1 serine phosphorylation Involvement of p38 MAPK in ethanol induction of ISRE transcription and Stat1 serine phosphorylation ... effect of CYP2E1 and ADH inhibition on ethanol activation of the ISRE Huh7 cells in 96 well plates were transfected in triplicate with 50 ηg of ISRE-luc and 12 hours later, were treated with mM of...
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Báo cáo hóa học: " Research Article Combination of Adaptive Feedback Cancellation and Binaural Adaptive Filtering in Hearing Aids" pot
... replicas of these undesired components, using a set of adaptive filters The solution adopted here consists of two 1×P SIMO systems of adaptive FIR filters, with transfer functions bL p and bR p ... kRR (53) where FL: and BL: denote the first row of F and B, respectively, that is, the transfer functions applied to the left LS signal FR: and BR: denote the second row of F and B, respectively, ... 1997 [6] M Doerbecker and S Ernst, “Combination of two-channel spectral subtraction and adaptive Wiener post-filtering for noise reduction and dereverberation,” in Proceedings of the 8th European...
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Báo cáo hóa học: "Research Article Adaptive Kernel Canonical Correlation Analysis Algorithms for Nonparametric Identification of Wiener and Hammerstein Systems" potx
... discuss an adaptive version of kernel CCA which can be used for online identification of Wiener and Hammerstein systems 4.1 Formulation of KCCA as coupled RLS problems The special structure of the ... regularize the adaptive version of the proposed KCCA algorithm 3.4 A Unified approach to Wiener and Hammerstein system identification and equalization To identify the linear channel and the inverse ... nonlinearity of the Wiener system, any of the regularized GEV problems (21), (23), or (25) can be solved Moreover, given the symmetric structure of the Wiener and Hammerstein systems (see Figures and...
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Báo cáo hóa học: " Research Article Experimental Evaluation of Adaptive Modulation and Coding in MIMO WiMAX with Limited " docx
... NOFDM sum (7) where G (1/4 in our measurements) corresponds to the ratio of cyclic prefix time and useful OFDM symbol time, Ndata (44 in our measurements) is the number of OFDM data symbols, NOFDM ... i∈I (1) where Ri corresponds to the data rate of the ith adaptive modulation and coding scheme (i ∈ I, where I is the set of all adaptive schemes) and Pi(c,m) ∈ {0, 1} is a frame error indicator ... measurements, we chose a channel bandwidth of MHz For this channel bandwidth, the WiMAX standard defines a sampling rate of Ts = 1/5.76 MHz The 5.76 MHz total signal bandwidth emerging from this sampling...
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