stem cells and regenerative medicine

... PROJECT OVERVIEW AND DEFINITIONS ADULT STEM CELLS 19 EMBRYONIC STEM CELLS 31 OPPORTUNITIES FOR AND BARRIERS TO PROGRESS IN STEM CELL RESEARCH FOR REGENERATIVE MEDICINE 41 FINDINGS AND RECOMMENDATIONS ... http://books.nap.edu/catalog/.html STEM CELLS AND THE FUTURE OF REGENERATIVE MEDICINE ment cells of the skin, cartilage and bone in the face and skull, and connective tissue in many parts of the body Neural crest cells from ... embryonic and adult human stem cells will be required to most efficiently advance the scientific and therapeutic potential of regenerative medicine Research on both adult and embryonic human stem cells...

Ngày tải lên: 15/03/2014, 09:20

... searchers have transplanted the bone marrow stem cells into the necrotic femoral heads, and results show bone marrow stem cells can remove vascular lesions and promote angiogenesis in necrotic femoral ... [19-21] Recently, in order to improve the efficacy of stem cell transplantation, committed stem cells are isolated and purified, and single lineage stem cell transplantation is then performed Deng ... expressed in injured tissues play important roles (2) Stem cells circulate among tissues, and stem cells migrate to the injured tissues once injury occurs Stem cell homing is a complicated process in...

Ngày tải lên: 25/10/2012, 11:18

... history and the most advanced discoveries in neural stem cells This book provides the strategies and challenges of utilizing neural stem cells for therapy of neurological disorders and brain and ... (slowly dividing astroglial cells and the bona fide adult neural stem cells) , type C cells (transit-amplifying cells derived from asymmetric division of Type B cells) , type A cells (immature neuroblasts ... Jiang Chapter 14 Endogenous Neural Stem/ Progenitor Cells and Regenerative Responses to Brain Injury 285 Maria Dizon Chapter 15 Neural Stem Cells: Exogenous and Endogenous Promising Therapies...

Ngày tải lên: 30/03/2014, 23:20

... novel circulating human embryonic blood stem cells Blood 96, 1740 - 1747 IItskovitz - Eldor, J and et al (2000).; Differentiation of human embryonic stem cells into embryoid bodies comprising the ... human pancreatic cell line in vitro and in vivo Mol Endocrinol 15, 476 - 483 Dzierzak, E et al (1998); Embryonic beginnings of definitive hematopoietic stem cells Ann N Y Acad Sci 872, 256 - 262 ... 814 - 822 Jones, G M., et al (2000); Human embryonic stem cells technology Semin Reprod Med 18, 219 - 223 Orlic D et al (2001); Bone marrow cells regenerate infarcted myocardium nature 410, 701...

Ngày tải lên: 02/04/2014, 22:20

... at 28 and 112 J/cm2 of human peripheral blood mononuclear cells, a heterogeneous population of T cells, B cells, NK cells, and monocytes has been described to induce chromatin relaxation and to ... Autologous bone marrow stem cells to treat acute myocardial infarction: a systematic review Eur Heart J 2008, 29:1807-1818 Vet -Stem Regenerative Veterinary Medicine http://www.vet -stem. com Lin et ... concentrate stem cells to an area of need, to modulate effects of stem cells once they are in that specific area, or even to use light together with other agents to modulate endogenous stem cells The...

Ngày tải lên: 18/06/2014, 16:20

... Telmer and Eva Turley Breast Cancer Stem Cells 235 Chapter 11 The Microenvironment of Breast Cancer Stem Cells Deepak Kanojia and Hexin Chen Chapter 12 Involvement of Mesenchymal Stem Cells in ... Microenvironment, Stem Cells and Metastasis McAteer, J., and Davis, J (2002) Basic cell culture technique and the maintenance of cell lines (Oxford, England, Oxford Press) McGarrity, G., and Coriell, ... lines, are ubiquitous and are used for everything By using cell lines, our understanding of cells and genes, how they function or malfunction, and how they interact with other cells has increased...

Ngày tải lên: 27/06/2014, 17:20

... repair and transplantation medicine There are several approaches in human clinical trails that employ adult stem cells (such as blood-forming hematopoietic stem cells and cartilage-forming cells) ... blood island and myocardium J Embryol Exp Morphol 1985, 87, 27-45 17 Draper JS, Moore HD, Ruban LN, Gokhale PJ, Andrews PW Culture and characterization of human embryonic stem cells Stem Cells Dev ... ES cells can become any and all cell types of the body and large numbers of ES cells can be relatively easily obtained in vitro culture Therefore, ES cells could be the choice of cells in stem...

Ngày tải lên: 07/08/2014, 18:21

... engineering and regeneration [134] Mesenchymal stem cells versus embryonic stem cells Embryonic stem (ES) cells are derived from the inner cell mass of the embryonic blastocyst These cells can ... ‘bone marrow stem cell’, which is often used for either hematopoietic or mesenchymal stem cells, the central nervous system stem cell, the hepatic stem cell, etc.? If many stem cells are found ... supports the survival and differentiation of stem cells These complementary approaches have been used to compare different groups of stem cells in order to identify core stem genes and to examine...

Ngày tải lên: 09/08/2014, 01:21

... embryonic stem cells and differentiation Nat Rev Mol Cell Biol 2006, 7:540-546 51 Park SH, Kook MC, Kim EY, Park S, Lim JH: Ultrastructure of human embryonic stem cells and spontaneous and retinoic ... AP: Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts Nat Genet 2009, 41:1350-1353 ... Wysocka J: Epigenomics of human embryonic stem cells and induced pluripotent stem cells: insights into pluripotency and implications for disease Genome Medicine 2011, 3:36 ...

Ngày tải lên: 11/08/2014, 12:21

... marrow stromal cells Stem Cells 2001, 19:219-25 10 Burt RK, Loh Y, Pearce W, Beohar N, Barr WG, Craig R, et al.: Clinical applications of blood-derived and marrow-derived stem cells for nonmalignant ... of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities Stem Cells 2007, 25:1737-1745 24 Segers VF, Van RI, Andries LJ, Lemmens K, Demolder ... Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University School of Medicine, Atlanta (GA), USA, 4Servei Pneumologia, Hospital Clínic-IDIBAPS, Barcelona, Spain and 5Institut...

Ngày tải lên: 12/08/2014, 11:22

... neuroepithelial cells and bodies, innervation, and classical hematopoieticallyderived cells such as dendritic cells, mast cells, and macrophages, has hindered identification of lung stem cells and patterns ... augment resident stem cells, and we comprehensively review such data from lung Finally, there is great hope that embryonic stem cells, embryonic germ cells, or even adult somatic stem cells can be ... stem cells may home to the lung There is great excitement and hope that exogenous and/ or mobilized endogenous stem cells may be harnessed to prevent or treat acute and chronic lung diseases and...

Ngày tải lên: 12/08/2014, 18:21

... expression of CD34 and represents a heterogeneous cell population encompassing stem cells, early pluripotent progenitor cells, multipotent progenitor cells, and uncommitted differentiating cells [8] HSCs ... cell types, including hematopoietic and stromal cells of the bone marrow, endothelial cells, epithelial cells, fibroblasts, neuronal cells, and smooth muscle cells [3,53-57] The bone marrow is ... Hematopoietic Stem Cells and Progenitors: Implications for Clinical Application Annual Review of Immunology 2003, 21:759-806 Reya T, Morrison SJ, Clarke MF, Weissman IL: Stem cells, cancer, and cancer stem...

Ngày tải lên: 12/08/2014, 23:23

... seeded with stem cells) In the context of this thesis, the term regenerative medicine refers to therapeutic approaches that aim at regenerating human cells, tissues, and organs and restoring ... summarizing HIF-1 and VEGF’s differential effects on endothelial cells and osteoblasts Through upregulation of VEGF, HIF-1 stimulates endothelial cells to form blood vessels, and promotes chemotactic ... function” The field has thus been expanded to encompass these other approaches, which include gene therapy, stem cell transplantation, reprogramming of cells and tissues, and the delivery of soluble factors...

Ngày tải lên: 09/09/2015, 11:11

... Mesenchymal Stem Cells In The Treatment Of Acute Myocardial Infarction With the emergence of stem cells as potential regenerative medicine, attempts to use stem cells to reduce infarct size and enhance ... Mesenchymal stem cells and their potential as cardiac therapeutics Circ Res 95, 9–20 Quesenberry, P.J., Aliotta, J.M., 2008 The paradoxical dynamism of marrow stem cells: considerations of stem cells, ... Carcinoma 40 Nephrology Renal and Urological Disease Renal and Urological System Development and Function Hair and Skin Development and Function Dermatological Diseases and Conditions Cardiovascular...

Ngày tải lên: 10/09/2015, 08:42

... underlying human nervous system development (Ben-Nun and Benvenisty, 2006; Dvash et al., 2006) 2.7 Embryonic stem cells and induced pluripotent stem cells Embryonic stem cells (ESC) have two characteristics ... variety of cells that make up the central nervous system including dopaminergic neurons, motor neurons, glial cells, astrocytes, oligodendrocytes, neural crest stem cell cells and retinal cells (Bjorklund ... Sandy, Andy and other seniors for sharing with me your experiences and giving me invaluable tips and advice on how to survive a PhD! Grace, April, Eunice, TSG, cell group members from CEFC and...

Ngày tải lên: 11/09/2015, 10:14

... thigh region, and used lentiviruses to induce the cells to pluripotent cells These pluripotent cells are studied and characterized The pluripotent stem cells exhibited morphology and genomic markers ... Aims and objectives 14 Literature Review 15 3.1 Human Embryonic Stem Cells (hESCs) 15 3.2 Porcine Embryonic Stem Cells 16 3.3 Generation of Induced Pluripotent Stem Cells ... to Induced Pluripotent Stem Cells 45 iv 4.10 Culture of Porcine Induced Pluripotent Stem Cells 45 4.10 Characterization of Porcine Induced Pluripotent Stem Cells 46 4.10.1 Immunocytochemical...

Ngày tải lên: 30/09/2015, 10:13

... embryonic stem cells 1.1.1 Overview and characteristics of human embryonic stem cells 1.1.2 Regulatory networks and transcription factors in human ES cells 1.1.3 Induced pluripotent stem cells 1.1.4 ... source of cells for regenerative medicine and cellular repair The key to utilizing the regenerative capability of human ES cells lies in elucidating the mechanisms underlying self-renewal and pluripotency, ... Page X Chapter Introduction 1.1 Human embryonic stem cells 1.1.1 Overview and characteristics of human embryonic stem cells Embryonic stem (ES) cells are isolated from the inner cell mass (ICM)...

Ngày tải lên: 16/10/2015, 11:58

... (non-hematopoietic stem cells) is still underway The nature of somatic stem/ progenitor cells is much different from that of embryonic stem (ES) cells and induced pluripotent stem (iPS) cells Somatic stem/ progenitor ... Matsuoka and Arinobu Tojo Cells for Regenerative Medicine 21 Chapter Bone and Cartilage from Stem Cells: Growth Optimalization and Stabilization of Cell Phenotypes 23 Jan O Gordeladze, Janne E Reseland, ... mesenchymal stem cells and their differentiation to osteoblasts Aging Cell, Vol 7, No 3, (June 2008), pp 335-343, ISSN 1474-9718 Part Cells for Regenerative Medicine Bone and Cartilage from Stem Cells: ...

Ngày tải lên: 28/06/2014, 05:20