... Telmer and Eva Turley Breast CancerStemCells 235 Chapter 11 The Microenvironment of Breast CancerStemCells Deepak Kanojia and Hexin Chen Chapter 12 Involvement of Mesenchymal StemCells in ... of breast cancer cells, molecular tumor classification methods, in vitro cancer models, breast cancerand microenvironment, breast cancerstem cells, gene regulation in breast cancer, and mechanism ... Muehlberg, F., Beckmann, C and Song, Y H (2009) Tissue resident stemcells produce CCL5 under the influence of cancercellsand thereby promote breast cancer cell invasion Cancer Lett, Vol 284, No.1:...
... searchers have transplanted the bone marrow stemcells into the necrotic femoral heads, and results show bone marrow stemcells can remove vascular lesions and promote angiogenesis in necrotic femoral ... [19-21] Recently, in order to improve the efficacy of stem cell transplantation, committed stemcells are isolated and purified, and single lineage stem cell transplantation is then performed Deng ... expressed in injured tissues play important roles (2) Stemcells circulate among tissues, andstemcells migrate to the injured tissues once injury occurs Stem cell homing is a complicated process in...
... explored the hypothesis that DNAmethylation is dependent on the absolute configurations and conformations of (+)-trans-B[a]P-N2-dG and (+)-cis-B[a]PN2-dG lesions DNAmethylation plays an important ... B[a]P-N2-dG adducts were compared with the levels of DNA methylation, and thus the effect of the absolute configurations and conformations of the adducts on DNAmethylation was not evaluated More recently, ... conformations on DNAmethylation In this work, the effect of the intercalated [9] (+)-cis-antiB[a]P-N2-dG adduct on the DNA binding and catalytic activity of SssI and HhaI was examined and compared...
... types: neural stem cells, including neural crest cells; hematopoietic stem cells; and pancreatic islet progenitors Neural stem cells, which are numerous in the fetal brain, can be isolated and grown ... cells derived from cultured mouse ESCs are fat cells, various brain and nervous system cells, insulin-producing cells of the pancreas, bone cells, hematopoietic cells, yolk sac, endothelial cells, ... embryonic stem cell lines In conjunction with research on stem cell biology and the development of stem cell therapies, research on approaches that prevent immune rejection of stemcellsand stem...
... history and the most advanced discoveries in neural stemcells This book provides the strategies and challenges of utilizing neural stemcells for therapy of neurological disorders and brain and ... (slowly dividing astroglial cellsand the bona fide adult neural stem cells) , type C cells (transit-amplifying cells derived from asymmetric division of Type B cells) , type A cells (immature neuroblasts ... Carvalho and Inês M Araújo Chapter 19 Immune System Modulation of Germinal and Parenchymal Neural Progenitor Cells in Physiological and Pathological Conditions 413 Chiara Rolando, Enrica Boda and...
... novel circulating human embryonic blood stemcells Blood 96, 1740 - 1747 IItskovitz - Eldor, J and et al (2000).; Differentiation of human embryonic stemcells into embryoid bodies comprising the ... human pancreatic cell line in vitro and in vivo Mol Endocrinol 15, 476 - 483 Dzierzak, E et al (1998); Embryonic beginnings of definitive hematopoietic stemcells Ann N Y Acad Sci 872, 256 - 262 ... 814 - 822 Jones, G M., et al (2000); Human embryonic stemcells technology Semin Reprod Med 18, 219 - 223 Orlic D et al (2001); Bone marrow cells regenerate infarcted myocardium nature 410, 701...
... at 28 and 112 J/cm2 of human peripheral blood mononuclear cells, a heterogeneous population of T cells, B cells, NK cells, and monocytes has been described to induce chromatin relaxation and to ... concentrate stemcells to an area of need, to modulate effects of stemcells once they are in that specific area, or even to use light together with other agents to modulate endogenous stemcells The ... N, O’Valle F, Hernandez-Cortes P, Rico L, Buscher D, Delgado M: Human adipose-derived mesenchymal stemcells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in...
... blood island and myocardium J Embryol Exp Morphol 1985, 87, 27-45 17 Draper JS, Moore HD, Ruban LN, Gokhale PJ, Andrews PW Culture and characterization of human embryonic stemcellsStemCells Dev ... adult stemcells is their inability to effectively grow in Human embryonic stemcellsand therapeutic cloning culture Therefore, obtaining clinically significant amounts of adult stemcells may ... ES cells can become any and all cell types of the body and large numbers of ES cells can be relatively easily obtained in vitro culture Therefore, ES cells could be the choice of cells in stem...
... engineering and regeneration [134] Mesenchymal stemcells versus embryonic stemcells Embryonic stem (ES) cells are derived from the inner cell mass of the embryonic blastocyst These cells can ... ‘bone marrow stem cell’, which is often used for either hematopoietic or mesenchymal stem cells, the central nervous system stem cell, the hepatic stem cell, etc.? If many stemcells are found ... supports the survival and differentiation of stemcells These complementary approaches have been used to compare different groups of stemcells in order to identify core stem genes and to examine...
... GQ, Feinberg AP: Differential methylation of tissue- and cancer- specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stemcellsand fibroblasts Nat Genet 2009, ... embryonic stemcellsand may be mediated by DNA methyltransferase 3a Proc Natl Acad Sci U S A 2000, 97:5237-5242 72 Altun G, Loring JF, Laurent LC: DNAmethylation in embryonic stemcells J Cell ... depletion of DNAmethylation from subcentromeric and subtelomeric regions correlates with blocks of H3K9me3 that mark these loci in iPSCs and somatic cells, but not in hESCs [79,90] Aberrant DNA methylation...
... marrow stromal cellsStemCells 2001, 19:219-25 10 Burt RK, Loh Y, Pearce W, Beohar N, Barr WG, Craig R, et al.: Clinical applications of blood-derived and marrow-derived stemcells for nonmalignant ... of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities StemCells 2007, 25:1737-1745 24 Segers VF, Van RI, Andries LJ, Lemmens K, Demolder ... mesenchymal stemcells into circulating blood Sleep 2009, 32:117-119 Javazon EH, Colter DC, Schwarz EJ, Prockop DJ: Rat marrow stromal cells are more sensitive to plating density and expand more...
... neuroepithelial cellsand bodies, innervation, and classical hematopoieticallyderived cells such as dendritic cells, mast cells, and macrophages, has hindered identification of lung stemcellsand patterns ... augment resident stem cells, and we comprehensively review such data from lung Finally, there is great hope that embryonic stem cells, embryonic germ cells, or even adult somatic stemcells can be ... stemcells may home to the lung There is great excitement and hope that exogenous and/ or mobilized endogenous stemcells may be harnessed to prevent or treat acute and chronic lung diseases and...
... Hematopoietic StemCellsand Progenitors: Implications for Clinical Application Annual Review of Immunology 2003, 21:759-806 Reya T, Morrison SJ, Clarke MF, Weissman IL: Stem cells, cancer, andcancerstem ... Leukemia Stem Cells/ CancerStemCells (LSC/CSC) The cancerstem cell hypothesis postulates that cancer can be initiated, sustained and maintained by a small number of malignant cells that have HSC-like ... cell types, including hematopoietic and stromal cells of the bone marrow, endothelial cells, epithelial cells, fibroblasts, neuronal cells, and smooth muscle cells [3,53-57] The bone marrow is...
... bào, tự đổi mới, biệt hóa nhiều dòng tế bào, tế bào gốc tạo tế bào gốc TẾ BÀO GỐC UNG THƯ (CANCER STEM CELL - CSC) Tế bào ung thư tạo bướu (bướu đặc bướu huyết học), đặc biệt khả làm phát sinh...
... Mesenchymal stemcellsand their potential as cardiac therapeutics Circ Res 95, 9–20 Quesenberry, P.J., Aliotta, J.M., 2008 The paradoxical dynamism of marrow stem cells: considerations of stem cells, ... Carcinoma 40 Nephrology Renal and Urological Disease Renal and Urological System Development and Function Hair and Skin Development and Function Dermatological Diseases and Conditions Cardiovascular ... Organismal Injury and Abnormalities Tumor Morphology Genetic Disorder Cancer Skeletal and Muscular System Development and Function Connective Tissue Development and Function Skeletal and Muscular...
... underlying human nervous system development (Ben-Nun and Benvenisty, 2006; Dvash et al., 2006) 2.7 Embryonic stemcellsand induced pluripotent stemcells Embryonic stemcells (ESC) have two characteristics ... variety of cells that make up the central nervous system including dopaminergic neurons, motor neurons, glial cells, astrocytes, oligodendrocytes, neural crest stem cell cellsand retinal cells (Bjorklund ... 9! 2.4! SHH and neural development 10! iii 2.5! SHH and proliferation 14! 2.6! SHH in developmental disorders andcancer 15! 2.7! Embryonic stemcellsand induced...
... thigh region, and used lentiviruses to induce the cells to pluripotent cells These pluripotent cells are studied and characterized The pluripotent stemcells exhibited morphology and genomic markers ... Aims and objectives 14 Literature Review 15 3.1 Human Embryonic StemCells (hESCs) 15 3.2 Porcine Embryonic StemCells 16 3.3 Generation of Induced Pluripotent StemCells ... to Induced Pluripotent StemCells 45 iv 4.10 Culture of Porcine Induced Pluripotent StemCells 45 4.10 Characterization of Porcine Induced Pluripotent StemCells 46 4.10.1 Immunocytochemical...
... embryonic stemcells 1.1.1 Overview and characteristics of human embryonic stemcells 1.1.2 Regulatory networks and transcription factors in human ES cells 1.1.3 Induced pluripotent stemcells 1.1.4 ... Page X Chapter Introduction 1.1 Human embryonic stemcells 1.1.1 Overview and characteristics of human embryonic stemcells Embryonic stem (ES) cells are isolated from the inner cell mass (ICM) ... Embryonic StemCells Undifferentiated HES4 Human Embryonic StemCells SAGE_Embryonic _stem_ cell_H9_normal_p38_CL_SHES1 LSAGE_Embryonic _stem_ cell_BG01_normal_p20_CL_SHE19 LSAGE_Embryonic _stem_ cell_H13_normal_p22_CL_SHE15...