dna methylation stem cells and cancer

... Telmer and Eva Turley Breast Cancer Stem Cells 235 Chapter 11 The Microenvironment of Breast Cancer Stem Cells Deepak Kanojia and Hexin Chen Chapter 12 Involvement of Mesenchymal Stem Cells in ... of breast cancer cells, molecular tumor classification methods, in vitro cancer models, breast cancer and microenvironment, breast cancer stem cells, gene regulation in breast cancer, and mechanism ... Muehlberg, F., Beckmann, C and Song, Y H (2009) Tissue resident stem cells produce CCL5 under the influence of cancer cells and thereby promote breast cancer cell invasion Cancer Lett, Vol 284, No.1:...

Ngày tải lên: 27/06/2014, 17:20

... searchers have transplanted the bone marrow stem cells into the necrotic femoral heads, and results show bone marrow stem cells can remove vascular lesions and promote angiogenesis in necrotic femoral ... [19-21] Recently, in order to improve the efficacy of stem cell transplantation, committed stem cells are isolated and purified, and single lineage stem cell transplantation is then performed Deng ... expressed in injured tissues play important roles (2) Stem cells circulate among tissues, and stem cells migrate to the injured tissues once injury occurs Stem cell homing is a complicated process in...

Ngày tải lên: 25/10/2012, 11:18

... explored the hypothesis that DNA methylation is dependent on the absolute configurations and conformations of (+)-trans-B[a]P-N2-dG and (+)-cis-B[a]PN2-dG lesions DNA methylation plays an important ... B[a]P-N2-dG adducts were compared with the levels of DNA methylation, and thus the effect of the absolute configurations and conformations of the adducts on DNA methylation was not evaluated More recently, ... conformations on DNA methylation In this work, the effect of the intercalated [9] (+)-cis-antiB[a]P-N2-dG adduct on the DNA binding and catalytic activity of SssI and HhaI was examined and compared...

Ngày tải lên: 19/02/2014, 00:20

... types: neural stem cells, including neural crest cells; hematopoietic stem cells; and pancreatic islet progenitors Neural stem cells, which are numerous in the fetal brain, can be isolated and grown ... cells derived from cultured mouse ESCs are fat cells, various brain and nervous system cells, insulin-producing cells of the pancreas, bone cells, hematopoietic cells, yolk sac, endothelial cells, ... embryonic stem cell lines In conjunction with research on stem cell biology and the development of stem cell therapies, research on approaches that prevent immune rejection of stem cells and stem...

Ngày tải lên: 15/03/2014, 09:20

... history and the most advanced discoveries in neural stem cells This book provides the strategies and challenges of utilizing neural stem cells for therapy of neurological disorders and brain and ... (slowly dividing astroglial cells and the bona fide adult neural stem cells) , type C cells (transit-amplifying cells derived from asymmetric division of Type B cells) , type A cells (immature neuroblasts ... Carvalho and Inês M Araújo Chapter 19 Immune System Modulation of Germinal and Parenchymal Neural Progenitor Cells in Physiological and Pathological Conditions 413 Chiara Rolando, Enrica Boda and...

Ngày tải lên: 30/03/2014, 23:20

... novel circulating human embryonic blood stem cells Blood 96, 1740 - 1747 IItskovitz - Eldor, J and et al (2000).; Differentiation of human embryonic stem cells into embryoid bodies comprising the ... human pancreatic cell line in vitro and in vivo Mol Endocrinol 15, 476 - 483 Dzierzak, E et al (1998); Embryonic beginnings of definitive hematopoietic stem cells Ann N Y Acad Sci 872, 256 - 262 ... 814 - 822 Jones, G M., et al (2000); Human embryonic stem cells technology Semin Reprod Med 18, 219 - 223 Orlic D et al (2001); Bone marrow cells regenerate infarcted myocardium nature 410, 701...

Ngày tải lên: 02/04/2014, 22:20

... at 28 and 112 J/cm2 of human peripheral blood mononuclear cells, a heterogeneous population of T cells, B cells, NK cells, and monocytes has been described to induce chromatin relaxation and to ... concentrate stem cells to an area of need, to modulate effects of stem cells once they are in that specific area, or even to use light together with other agents to modulate endogenous stem cells The ... N, O’Valle F, Hernandez-Cortes P, Rico L, Buscher D, Delgado M: Human adipose-derived mesenchymal stem cells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in...

Ngày tải lên: 18/06/2014, 16:20

... blood island and myocardium J Embryol Exp Morphol 1985, 87, 27-45 17 Draper JS, Moore HD, Ruban LN, Gokhale PJ, Andrews PW Culture and characterization of human embryonic stem cells Stem Cells Dev ... adult stem cells is their inability to effectively grow in Human embryonic stem cells and therapeutic cloning culture Therefore, obtaining clinically significant amounts of adult stem cells may ... ES cells can become any and all cell types of the body and large numbers of ES cells can be relatively easily obtained in vitro culture Therefore, ES cells could be the choice of cells in stem...

Ngày tải lên: 07/08/2014, 18:21

... engineering and regeneration [134] Mesenchymal stem cells versus embryonic stem cells Embryonic stem (ES) cells are derived from the inner cell mass of the embryonic blastocyst These cells can ... ‘bone marrow stem cell’, which is often used for either hematopoietic or mesenchymal stem cells, the central nervous system stem cell, the hepatic stem cell, etc.? If many stem cells are found ... supports the survival and differentiation of stem cells These complementary approaches have been used to compare different groups of stem cells in order to identify core stem genes and to examine...

Ngày tải lên: 09/08/2014, 01:21

... GQ, Feinberg AP: Differential methylation of tissue- and cancer- specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts Nat Genet 2009, ... embryonic stem cells and may be mediated by DNA methyltransferase 3a Proc Natl Acad Sci U S A 2000, 97:5237-5242 72 Altun G, Loring JF, Laurent LC: DNA methylation in embryonic stem cells J Cell ... depletion of DNA methylation from subcentromeric and subtelomeric regions correlates with blocks of H3K9me3 that mark these loci in iPSCs and somatic cells, but not in hESCs [79,90] Aberrant DNA methylation...

Ngày tải lên: 11/08/2014, 12:21

... marrow stromal cells Stem Cells 2001, 19:219-25 10 Burt RK, Loh Y, Pearce W, Beohar N, Barr WG, Craig R, et al.: Clinical applications of blood-derived and marrow-derived stem cells for nonmalignant ... of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities Stem Cells 2007, 25:1737-1745 24 Segers VF, Van RI, Andries LJ, Lemmens K, Demolder ... mesenchymal stem cells into circulating blood Sleep 2009, 32:117-119 Javazon EH, Colter DC, Schwarz EJ, Prockop DJ: Rat marrow stromal cells are more sensitive to plating density and expand more...

Ngày tải lên: 12/08/2014, 11:22

... neuroepithelial cells and bodies, innervation, and classical hematopoieticallyderived cells such as dendritic cells, mast cells, and macrophages, has hindered identification of lung stem cells and patterns ... augment resident stem cells, and we comprehensively review such data from lung Finally, there is great hope that embryonic stem cells, embryonic germ cells, or even adult somatic stem cells can be ... stem cells may home to the lung There is great excitement and hope that exogenous and/ or mobilized endogenous stem cells may be harnessed to prevent or treat acute and chronic lung diseases and...

Ngày tải lên: 12/08/2014, 18:21

... Hematopoietic Stem Cells and Progenitors: Implications for Clinical Application Annual Review of Immunology 2003, 21:759-806 Reya T, Morrison SJ, Clarke MF, Weissman IL: Stem cells, cancer, and cancer stem ... Leukemia Stem Cells/ Cancer Stem Cells (LSC/CSC) The cancer stem cell hypothesis postulates that cancer can be initiated, sustained and maintained by a small number of malignant cells that have HSC-like ... cell types, including hematopoietic and stromal cells of the bone marrow, endothelial cells, epithelial cells, fibroblasts, neuronal cells, and smooth muscle cells [3,53-57] The bone marrow is...

Ngày tải lên: 12/08/2014, 23:23

... bào, tự đổi mới, biệt hóa nhiều dòng tế bào, tế bào gốc tạo tế bào gốc TẾ BÀO GỐC UNG THƯ (CANCER STEM CELL - CSC) Tế bào ung thư tạo bướu (bướu đặc bướu huyết học), đặc biệt khả làm phát sinh...

Ngày tải lên: 27/08/2014, 19:00

... Mesenchymal stem cells and their potential as cardiac therapeutics Circ Res 95, 9–20 Quesenberry, P.J., Aliotta, J.M., 2008 The paradoxical dynamism of marrow stem cells: considerations of stem cells, ... Carcinoma 40 Nephrology Renal and Urological Disease Renal and Urological System Development and Function Hair and Skin Development and Function Dermatological Diseases and Conditions Cardiovascular ... Organismal Injury and Abnormalities Tumor Morphology Genetic Disorder Cancer Skeletal and Muscular System Development and Function Connective Tissue Development and Function Skeletal and Muscular...

Ngày tải lên: 10/09/2015, 08:42

... underlying human nervous system development (Ben-Nun and Benvenisty, 2006; Dvash et al., 2006) 2.7 Embryonic stem cells and induced pluripotent stem cells Embryonic stem cells (ESC) have two characteristics ... variety of cells that make up the central nervous system including dopaminergic neurons, motor neurons, glial cells, astrocytes, oligodendrocytes, neural crest stem cell cells and retinal cells (Bjorklund ... 9! 2.4! SHH and neural development 10! iii 2.5! SHH and proliferation 14! 2.6! SHH in developmental disorders and cancer 15! 2.7! Embryonic stem cells and induced...

Ngày tải lên: 11/09/2015, 10:14

... thigh region, and used lentiviruses to induce the cells to pluripotent cells These pluripotent cells are studied and characterized The pluripotent stem cells exhibited morphology and genomic markers ... Aims and objectives 14 Literature Review 15 3.1 Human Embryonic Stem Cells (hESCs) 15 3.2 Porcine Embryonic Stem Cells 16 3.3 Generation of Induced Pluripotent Stem Cells ... to Induced Pluripotent Stem Cells 45 iv 4.10 Culture of Porcine Induced Pluripotent Stem Cells 45 4.10 Characterization of Porcine Induced Pluripotent Stem Cells 46 4.10.1 Immunocytochemical...

Ngày tải lên: 30/09/2015, 10:13

... embryonic stem cells 1.1.1 Overview and characteristics of human embryonic stem cells 1.1.2 Regulatory networks and transcription factors in human ES cells 1.1.3 Induced pluripotent stem cells 1.1.4 ... Page X Chapter Introduction 1.1 Human embryonic stem cells 1.1.1 Overview and characteristics of human embryonic stem cells Embryonic stem (ES) cells are isolated from the inner cell mass (ICM) ... Embryonic Stem Cells Undifferentiated HES4 Human Embryonic Stem Cells SAGE_Embryonic _stem_ cell_H9_normal_p38_CL_SHES1 LSAGE_Embryonic _stem_ cell_BG01_normal_p20_CL_SHE19 LSAGE_Embryonic _stem_ cell_H13_normal_p22_CL_SHE15...

Ngày tải lên: 16/10/2015, 11:58