stage 4 non small cell lung cancer clinical trials
Báo cáo khoa học: "Clinical outcomes of stereotactic body radiotherapy for stage I non-small cell lung cancer using different doses depending on tumor size" ppsx
... 65 2 47 161 48 0 31 172110 74 Tumor size (mm)Range (median) 12-55 (27) 12, 14 15- 34 ( 24) 31-55 (35)OperabilityOperable 40 2 27 11 Non- operable 84 0 58 26HistologyAdenocarcinoma 66 2 46 18Squamous ... early- stage non- small- cell lung cancer: clinical implications. Radiother Oncol2010, 94: 1-11.27. Chen Y, Guo W, Lu Y, Zou B: Dose-individualized stereotactic bodyradiotherapy for T1-3N0 non- small ... IA Stage IBPrescribed dose (in 4 fractions) All 44 Gy 48 Gy 52 GyPatient number 1 24 2 85 37Age (years)Range (median) 29-89 (77) 67, 70 58-87 (77) 29-89 (78)GenderMale 84 1 54 29Female 40 ...
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Báo cáo hóa học: " Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer" pdf
... Non- small- cell lung cancer harbouring mutations in the EGFRkinase domain. Clin Transl Oncol 2010, 12:75-80.9. Gazdar AF: Activating and resistance mutations of EGFR in non- small- cell lung cancer: ... 70 343 1 94 340 60Age, yearsrange 36-85 42 -83 27-88median 64 67 59.9Sexmale 28 31 36female 50 30 34 EthnicityCaucasian 78 61 0 0 0Asian 0 0 70 343 60Smoking historysmokers 33 37 41 non- smokers ... lung cancer patients.Methods: EGFR mutation status was analyzed by DNA assays, and compared with IHC results in five non- small- cell lung cancer (NSCLC) cell lines and tumor samples from 78 stage...
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Báo cáo khoa học: " Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer" docx
... prospective clinical studies are needed.Keywords: Stereotactic Body Rad iotherapy, Oligometastases, Non- Small Cell Lung Cancer Background Non- small cell lung cancer (NSCLC) is the leadingcause of cancer ... of 7 RESEARC H Open AccessComparison of outcomes in patients with stage IIIversus limited stage IV non- small cell lung cancer Praveena Cheruvu1, Su K Metcalfe1, Justin Metcalfe1, Yuhchyau ... limited metastatic stage IV. Fifty-five of the 94 patients with initial stage IIINSCLC ( 74% ) developed radiographically apparentmetastases, of whom 44 developed limited metastatic stage IV disease...
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Báo cáo khoa học: "Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study" pps
... patients withoperable lung cancer. A randomized phase III trial of Radiosurgery Or Surgeryfor operable Early stage (stage 1A) non- small cell Lung cancer (ROSEL, ClinicalTrials.gov ID = NCT00687986)has ... body radiotherapy for stage I non- small cell lung cancer. Radiother Oncol 2007, 85 :42 9 -43 4.39. Sinha B, McGarry RC: Stereotactic body radiotherapy for bilat-eral primary lung cancers: the Indiana ... Phys 2007, 66:1120-11 24. 40 . Haasbeek CJ, Senan S, Smit EF, Paul MA, Slotman BJ, Lagerwaard FJ:Critical review of nonsurgical treatment options for stage I non- small cell lung cancer. Oncologist...
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Báo cáo khoa học: " Stereotactic, single-dose irradiation of stage I non-small cell lung cancer and lung metastases" docx
... peripheral stage I non- small cell lung cancer. Lung Cancer 1999, 26:137- 142 .23. Slotman BJ, Antonisse IE, Njo KH: Limited field irradiation inearly stage (T1-2N0) non- small cell lung cancer. RadiotherOncol ... not for citation purposes)inoperable non- small cell lung cancer without mediastinalinvolvement (clinical stage N0, N1). Strahlenther Onkol 1996,172 :48 9 -49 5.22. Hayakawa K, Mitsuhashi N, Saito ... stereotactic Radioablation. Resultsof a phase I study in medically inoperable stage I non- small cell lung Cancer. Chest 2003, 1 24: 1 946 -1955.11. Lee S, Choi EK, Park HJ, Ahn SD, Kim JH, Kim KJ, Yoon SM,...
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Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
... = 4. 64 0.011V40 8.20% (3.29-13.61%) = 5.91, SD = 2 .48 = 9.26, SD = 3.750.015V45 7 .42 % (2.73-10.99%) = 4. 41, SD = 2.25 = 6. 54, SD = 3 .47 0.007V50 7.07%(1. 94- 8.82%) = 3.15, SD = 1. 94 = 4. 89, ... = 2 .40 0.001V5 58.73% (32.89-97.65%) = 58 .43 , SD = 16.57 = 69.23, SD = 12 .47 0.006V10 42 .16%(25.28-83. 34% ) = 41 .13, SD = 12.69 = 52 .42 , SD = 11.050.001V15 29.53%(16 .46 -58.51%) = 28. 94, ... conformal radiation therapy for non- small cell lung cancer. Radiother Oncol 1997, 44 :17-22. 14. Graham MV, Purdy JA, Emami B, Harms W, Bosch W, Lockett MA, Perez CA: Clinical dose-volume histogram...
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Báo cáo khoa học: " Absence of toxicity with hypofractionated 3-dimensional radiation therapy for inoperable, early stage non-small cell lung cancer" pot
... as lung cancer. It is more convenient for the patients and reduces health care costs.This study reports our results on patients with medically inoperable, early stage, non- small cell lung cancer ... therapy for inoperable, early stage non- small cell lung cancer Sergio L Faria*1, Luis Souhami1, Lorraine Portelance1, Marie Duclos1, Te Vuong1, David Small 2 and Carolyn R Freeman1Address: ... hypofractionated radiation therapyis an attractive option for patients with early stage non- small cell lung cancer (NSCLC) who are not surgical can-didates. Although primarily appealing for...
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báo cáo hóa học:" Randomized phase II study with two gemcitabine- and docetaxel-based combinations as first-line chemotherapy for metastatic non-small cell lung cancer" docx
... (B).0 4 8 121620 242 8323 640 444 852Weeks00.20 .4 0.60.81TTPPatients Events (%)Arm A 35 33 ( 94. 3)Arm B 34 32 ( 94. 1)A0 4 8 12 16 20 24 28 32 36 40 44 48 52Weeks00.20 .4 0.60.81SurvivalPatients ... Estimating the world cancer burden: Globocan 2000. Int J Cancer 2001, 94: 153-156.2. Non- small Cell Lung Cancer Collaborative Group: Chemotherapyin non small cell lung cancer: a meta-analysis ... 14 (35) 12 (29.3)Other NSCLC 4 (10) 6 ( 14. 6)Site of disease Lung ± lymph nodes 14 (35) 14 ( 34. 1) Lung and 1 metastatic site 12 (30) 15 (36.6) Lung and ≥ 2 metastatic sites 9 (22.5) 10 ( 24. 4)Extra-pulmonary...
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Báo cáo hóa học: "Prognostic Impact of MiR-155 in Non-Small Cell Lung Cancer Evaluated by in Situ Hybridization" pot
... 138 41 47 47 Moderate 144 43 190 64 Well 53 16 NR 68Surgical procedure 0.0 04 Lobectomy + Wedge* 243 73 190 61Pneumonectomy 92 27 37 47 Pathological stage <0.001I 157 47 190 71II 136 41 ... MiR-155 in Non- Small Cell Lung Cancer Evaluated by in Situ HybridizationTom Donnem1,2*, Katrine Eklo3 ,4 , Thomas Berg3 ,4 , Sveinung W Sorbye3 ,4 , Kenneth Lonvik3 ,4 , Samer Al-Saad3 ,4 ,Khalid ... 2009, 14: 253-63.23. Donnem T, Al-Saad S, Al-Shibli K, et al: Inverse prognostic impact ofangiogenic marker expression in tumor cells versus stromal cells in non small cell lung cancer. Clin Cancer...
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báo cáo hóa học: " Health state utilities for non small cell lung cancer" pot
... Big Lung Trial in Non- Small- Cell Lung cancer. Journal of Clinical Oncology 2005, 30: 741 7- 742 7.12. Silvestri G, Pritchard R, Welch HG: Preferences for chemother-apy in patients with advanced non- small ... Staging of small cell and non- small cell lung cancer. University of Iowa Virtual Hos-pital; 1999. 6. Hopwood P, Stephens RJ: Symptoms at presentation for treat-ment in patients with lung cancer: ... [ 34] . Osoba et al. [ 34] studied the stated pref-erences of 40 0 patients with either breast, colorectal orNSCLC and in either early stages (stage I or II) or latestages (stage III or IV) of cancer. ...
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Báo cáo toán học: "Molecular Predictors of EGFR-TKI Sensitivity in Advanced Non–small Cell Lung Cancer" ppsx
... non- small cell lung cancer cell lines. Mol Cancer Res. 2006; 4( 8): 521-8. 102. Taguchi F, Solomon B, Gregorc V, et al. Mass spectrometry to classify non- small- cell lung cancer patients for clinical ... the leading cause of cancer death world-wide (1). Lung cancer is generally classified into two histological types, small cell lung cancer (SCLC) and non small cell lung cancer (NSCLC). NSCLC ... in non- small cell lung cancer Is correlated with survival. Clin Cancer Res. 2001; 7(7): 1850-5. 93. Cappuzzo F, Gregorc V, Rossi E, et al. Gefitinib in pretreated non- small- cell lung cancer...
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Báo cáo khoa học: "Pathological complete response induced by first-line chemotherapy with single agent docetaxel in a patient with advanced non small cell lung cancer" pptx
... 8:8http://www.wjso.com/content/8/1/8Page 3 of 4 CAS E REP O R T Open AccessPathological complete response induced byfirst-line chemotherapy with single agentdocetaxel in a patient with advanced non small cell lung cancer Ferdinando ... Carteni’1AbstractBackground: Defining the optimal treatment for patients with inoperable non small cell lung cancer (NSCLC),presenting with metastatic mediastinal lymph nodes, is challenging. Nevertheless, ... few cycles should notautomatically discourage to continue treatment.IntroductionIn non- small cell lung cancer (NSCLC), mediastinallymphnode involvement comprises a wide spectrum ofseverity....
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Báo cáo khoa học: " Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer" potx
... (IAEA)consultants' meeting on elective nodal irradiation in lung cancer: non- small cell lung cancer (NSCLC). Int J Radiat OncolBiol Phys 2008, 72(2):335- 342 .6. Therasse P, Arbuck SG, Eisenhauer EA, Wanders ... in Stage III non- small cell lung cancer? An analysis of recur-rences in a phase II study of induction chemotherapy andinvolved-field radiotherapy. Int J Radiat Oncol Biol Phys 2002, 54( 4):999-1006.10. ... of fail-ure for non- small- cell lung cancer with position-emissiontomography/computed tomography defined target delinea-tion. Int J Radiat Oncol Biol Phy 2007, 69: 140 9- 141 6. 14. Chang DT, Zlotecki...
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