... Effects of abdominal and thoracic breathing on breathing pattern components in normal subjects and inpatientswithchronicobstructivepulmonarydisease American Review of Respiratory Disease ... representative recording of speech Patients were invited to be observed for a maximum of 24 hours A total of 109 hours of simultaneous recordings of video and LS were obtained Of that time, 73.9 ... environment for 24 continuous hours while wearing the ambulatory system Methods Subjects Eight subjects withchronicobstructivepulmonarydisease (COPD) who complained of cough as a prominent symptom...
... specifying the patient-important difference that investigators want to detect To find a difference of 1.5 points at a significance level of 0.05 and with a power of 80% and assuming a SD of points ... range commonly encountered inpatientswithchronic disease. [26,27] A change of 1.5 points corresponds approximately to a 20% change from these baseline scores Inpatientswith substantially lower ... Clinic proceedings 2002, 77(4):371-383 Puhan MA, Busching G, Schunemann HJ, VanOort E, Zaugg C, Frey M: Interval versus continuous high-intensity exerciseinchronicobstructivepulmonary disease: ...
... function and exercise capacity inpatientswithchronicobstructivepulmonarydisease Int J Tuberc Lung Dis 1999, 3(10):920-926 Fayers PM, Machin D: Quality of Life The Assessment, Analysis and Interpretation ... Celli BR: Gender and COPD inpatients attending a pulmonary clinic Chest 2005, 128:2012-2016 Anderson KL: The effect ofchronicobstructivepulmonarydisease on quality of life Res Nurs Health ... Batlle JS, Antò JM: Testing the measurement properties of the Spanish version of the SF-36 Health Survey among male patientswithchronicobstructivepulmonarydisease J Clin Epidemiol 1998, 51:1087-1094...
... study of three anticholinergic agents and fenoterol using a metered dose inhaler inpatientswithchronicobstructivepulmonarydisease Thorax 1995, 50:62-66 Littner MR, Ilowite JS, Tashkin DP, ... ofchronicobstructivepulmonarydisease 2009 Cazzola M, Matera MG, Lotvall J: Ultra long-acting beta 2-agonists in development for asthma and chronicobstructivepulmonarydisease Expert Opin ... Figure Impact of baseline FEV and dose on the improvement in trough FEV1 relative to baseline Page ofof 150 μg or higher provide sustained bronchodilation that is largely independent ofdisease severity...
... 349:1498-1504 CPMP/EWA/562/98: Points to consider on clinical investigation of medicinal products in the treatment ofpatientswithchronicobstructivepulmonarydisease (COPD) 1999 21 22 23 24 ... measure of quality of life for clinical trials inchronic lung diseases Thorax 1987, 42:773-778 Jaeschke R, Singer J, Guyatt GH: Measurement of health status Ascertaining the minimal clinically ... Friedman M, Wisniewski M, Rickard K: Use of a long-acting inhaled β2 adrenergic agonist, salmeterol xinafoate, inpatientswithchronicobstructivepulmonarydisease Am J Respir Crit Care Med 2001,...
... polymorphism and chronic inflammatory lung diseases, including bronchial asthma and COPD, suggesting that IL-17F may be critically involved in the pathogenesis ofchronic inflammatory lung diseases [15] ... Page of 10 Figure Double immunofluorescence staining for detection of IL-17A and IL-17F expression in CD4+ and CD8+ T cells in airways of COPD patients (A) Double immunofluorescence staining was ... the sections were incubated with streptavidin-HRP for and visualized with DAB/hydrogen peroxide After counterstaining with haematoxyline, sections were dehydrated in increasing ethanol gradient...
... represents TLRs staining of monocytes incubated with IL-6 mfi values of cells incubated with isotype matched antibodies were 4.3 ± 1.6 whereas mfi values of IL-6-treated cells incubated with isotype ... role in the in study design; in the collection, analysis, and interpretation of data; in the writing of the report; and in the decision to submit the paper for publication References Our findings ... blocking the effect of IL-6 on TLR-2 expression using an antibody against the receptor of this cytokine [44,45] or blocking the IL-6 intracellular signalling pathway through the induction of SOCS3,...
... http://ccforum.com/content/15/2/420 Page of Published: 27 April 2011 References He H, Ding L, Li F, Zhan Q: Clinical features of invasive bronchial -pulmonary aspergillosis in critically ill patientswithchronicobstructive ... Miguel J, Bouza E: Pulmonary aspergillosis inpatientswithchronicobstructivepulmonary disease: incidence, risk factors, and outcome Clin Microbiol Infect 2010, 16:870-877 doi:10.1186/cc10138 ... National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group Clin Infect Dis 2008, 46:1813-1821 Bulpa P, Dive A, Sibille Y: Invasive pulmonary aspergillosis in...
... measure of quality of life for clinical trials inchronic lung disease Thorax 1987, 42(10):773-778 Standards for the diagnosis and care ofpatientswithchronicobstructivepulmonarydisease ... Miravitlles M: Exacerbations worsen the quality of life ofchronicobstructivepulmonarydiseasepatientsin primary healthcare International journal of clinical practice 2008, 62(4):585-592 Guyatt ... DJ, Wedzicha JA: Effect of exacerbation on quality of life inpatientswithchronicobstructivepulmonarydisease American journal of respiratory and critical care medicine 1998, 157(5 Pt 1):1418-1422...
... measure of quality of life for clinical trials inchronic lung disease Thorax 1987, 42(10):773-778 Standards for the diagnosis and care ofpatientswithchronicobstructivepulmonarydisease ... Miravitlles M: Exacerbations worsen the quality of life ofchronicobstructivepulmonarydiseasepatientsin primary healthcare International journal of clinical practice 2008, 62(4):585-592 Guyatt ... DJ, Wedzicha JA: Effect of exacerbation on quality of life inpatientswithchronicobstructivepulmonarydisease American journal of respiratory and critical care medicine 1998, 157(5 Pt 1):1418-1422...
... training The training was intensive starting at 80% of the patients maximum walk speed on treadmill, and included also intensive step training The patients were encouraged and supervised during ... Clinical routine rehabilitation ofpatientswithchronicobstructivepulmonarydisease at regional hospital 27 Chapter 4: Methodological considerations In order to interpret the findings of ... are interesting in the context of the current initiatives concerning the monitoring of clinical routine rehabilitation of COPD patientsIn Central Denmark Region is has been decided to make an intensive...
... reduced in nine of our patients, including six with a normal BMI This suggests preferential skeletal muscle mass loss in 20% of our patients, which is in keeping with levels reported inpatientswith ... view of bone thinning and osteoporosis occurring largely as a result of CS use is simplistic Our findings could be interpreted as indicating a disease specific component involved in the loss of ... impact of inhaled CS on bone status is unclear with conflicting findings in terms of the rate of loss of BMD, the risk of osteoporosis and the risk of fractures [14-20] Many studies on the effect of...
... Mariscal D, Gallego M, Domingo C, Valles J: Invasive pulmonary aspergillosis inpatientswithchronicobstructivepulmonary disease: report of eight cases and review Clin Infect Dis 1998, 26:1473-1475 ... overfitting, yielding spurious findings, which made a large 95% CI for OR in our analysis Increasing the sample size and collecting more IBPA cases in a further study may avoid this kind oflimitation ... ethics committee, and written, informed consents were obtained from the patients or their next of kin Processing of clinical samples LRT samples of all patients included in this study were taken once...
... Ablation is indicated inpatientswith bundle-branch reentrant VT Ablation is indicated as adjunctive therapy inpatientswith an ICD who are receiving multiple shocks as a result of sustained VT ... Ranolazine in Ischemic Heart Disease Background • Anti-anginal & anti-ischemic effects without clinically significant effect on HR or BP • Approved for treatment ofchronic angina – exercise ... incidence of SCD • ♥ Amiodarone: No definite survival benefit; some studies have shown reduction in SCD inpatientswith LV dysfunction especially when given in conjunction with BB Has complex drug interactions...
... albumin Human serum albumin (HSA) is a single nonglycosylated polypeptide containing 35 cysteine residues all involved in the formation of stabilising disulphide bonds except 34cysteine In plasma, ... significant interaction of COPD with smoking (P < 0.001) Relationship between smoking status and levels of carbonylated HSA Since smoking status influenced baseline levels of HSA we next investigated ... (10, 11) In particular oxidised HSA is a reliable marker of oxidative stress inpatientswithchronic renal failure and individuals on hemodialysis therapy (12) In light of these findings the...
... informed consent was obtained from the patients' next of kin In cases in which patients regained the capacity to give consent, this was later obtained from them The patients were studied during ... β2Figure (Rint) remained less than 85% of baseline in each patient Time after salmeterol administration that minimum inspiratory resistance (Rint) remained less than 85% of baseline in each patient ... a fixed dosing interval for salmeterol in mechanically ventilated patientswith COPD exacerbation Instead of the use of a standard dosing regimen, individualization of the dose interval titrated...
... during sleep using MPA[20] Although the maximum inspiratory slope was already at baseline within normal postmenopausal range, MPA almost doubled the slope This finding is in line with the thinking ... threshold of the respiratory center is maintained longer in subjects with respiratory impairment than in healthy subjects The elimination of MPA might be slower in diseased patients than in healthy individuals ... Background Chronicobstructivepulmonarydisease (COPD), consisting of variable degrees ofpulmonary emphysema and chronicobstructive bronchitis, has a male predominance However, the prevalence of COPD...
... length of the Rbm within the microscopic field of vision was then measured with the aid of automated software mm length of the Rbm was included in the measurement Fragmentation of the Rbm included ... compatible with the correlation of smoking history and length of splitting in our study and also explains the observed nonhomogeneity of the width of the Rbm in smokers However, the presence of splitting ... factor influencing the main findings Conclusions This study examined novel aspects of Rbm and vascular remodelling in large airway biopsies in current smokers with normal lung function and patients...
... deficiency patientswith granulomata [19,20] In contrast, a lower frequency of the minor allele was reported in RA patients, whereas inpatientswith idiopathic pulmonary fibrosis no association with ... and asthma [12] patients, indicating that this cytokine is involved in both the local and systemic inflammation present in COPD Analysis of possible TNF-α gene polymorphisms in COPD could be ... in one second (FEV1) had to be less than 70% of the reference value, and the increase in FEV1 after inhalation of a β2-agonist less than 10% of the reference value Patientswith α1-antitrypsin...
... more functional limitationin the final model, mirroring findings in other chronic arthritic conditions [19,24,29,31-34] Our findings are also consistent with a previous report linking helplessness ... utilization of coping strategies inpatientswithchronic pain when their pain is at a moderate level of intensity or greater The VPMI has two validated subscales: active coping and passive coping [24] ... explained 49% of variance in BASFI scores More specifically, each numerical increase (range of scores to 27, with higher numbers equaling more depression) in depression resulted in an increase of...