... plasma levels of anti-inflammatory and inflammatory cytokines including interleukin-6 (IL6), IFN-g, IL-10 and transforming growth factor-beta (TGF-b) inpatientswith peripheral arteriosclerosis obliterans, ... aminotransferase (ALT), aspartate aminotransferase (AST), urea and creatinine of patientsand control subjects are shown in Table Patientsand control subjects presented levels within the normal range Thus, ... monocytes from control subjects andpatients to develop fungicidal activity against C albicans in vitro was evaluated before and after incubation with two cytokines involved in the activation process...
... verified by studies performed withpatientswith respiratory failure, with depression being observed in 30% of patientswith moderate failure andin 50% inpatientswith severe obstructive pulmonary ... suffocating disease status may explain the high percentage of depression inpatientswith COPD and BA in the study, which was higher than the percentage reported in studies performed with in- patients ... clinical experience accepts high comorbidity in pulmonary patients, studies assessing and comparing anxiety and depression levels among patientswith different pulmonary diseases are lacking in...
... anticoagulation inpatients receiving RRT during DrotAA infusion is not routinely necessary and does not improve FST The use of DrotAA inpatientswith severe sepsis requiring RRT is safe and is not ... anticoagulation inpatients receiving RRT during DrotAA infusion is not routinely necessary and does not improve FST The use of DrotAA inpatientswith severe sepsis requiring RRT is safe and is not ... difference in the minimum value of haemoglobin during DrotAA andin the post-DrotAA period (Table 4) A larger proportion of patients required platelet transfusion during DrotAA infusion compared with...
... symptomatology, including pain and itching, combined with concerns about the appearance of one's skin can substantially affect a patient's psychological well-being and can result in emotional distress, ... Abbott Laboratories with the original Phase III study design and acquisition of data All authors were involved in drafting the manuscript and critically reviewing it for intellectual content ... life with infliximab induction and maintenance therapy inpatientswith moderate-to-severe psoriasis: a randomized controlled trial Br J Dermatol 2006, 154(6):1161-1168 Krueger GG, Langley RG, Finlay...
... process involving increased arterial inflow and restricted venous outflow, coordinated with corpus cavernosum and penile arterial smooth muscle relaxation Any problem in this mechanism results in ... reasons predominate in the etiology of ED and it frequently appears along with atherosclerosis It is known that atherosclerotic lesions prevent blood flow into cavernosal tissues resulting in ED Pistachio ... Central and West Asia and distributed throughout the Mediterranean basin In Turkey, the pistachio is grown mainly in the city of Gaziantep.[4] Pistachio nuts are rich sources of plant proteins,...
... sites (single versus multiple); type of first-line chemotherapy (anthracycline- and/ or taxane-containing regimen versus other); previous line of hormonotherapy administered in metastatic setting ... months inpatients who received the maintenance treatment versus months inpatients under observation but again the overall survival curves were similar in both groups The French Epirubicin Study ... survival and overall survival after first line chemotherapy In 1997, Berruti et al analysed the factors influencing response rate and overall survival among 207 patients treated by epirubicin, followed...
... detected in all SS patients studied, but interestingly only in a minority of patientswith chronic sialoadenitis No staining for IL-18 was found in acinar cells, indicating that IL-18 production ... cytokine a prime candidate also in the pathogenesis of SS Increased serum levels and salivary gland expression of IL18 inpatientswith SS is in keeping with an active role for this cytokine in ... Box–whisker plots showing serum IL-18 concentration inpatientswith SS compared withpatientswith rheumatoid arthritis (RA) and normal healthy subjects (NHS) (a), andinpatientswith SS who are...
... Results IL-17 productionin PBMC from patientswith RA, patientswith OA and normal individuals PBMC were separated and cultured with PHA (5 µg/ml) from patientswith RA, patientswith OA, and age-matched ... found that the intracellular signaling pathway involving phosphoinositide 3-kinase (PI3K)/Akt and NF-κB might be involved in the overproduction of the key inflammatory cytokine IL-17 in RA These ... which interleukin 17 induces articular cartilage breakdown in vitro andin vivo Cytokine 2001, 16:10-21 LeGrand A, Fermor B, Fink C, Pisetsky DS, Weinberg JB, Vail TP, Guilak F: Interleukin-1,...
... (phosphate-buffered saline [PBS] containing 0.1% bovine serum albumin and 0.1% sodium azide) and incubated on ice for five minutes with 10 µg purified human immunoglobulin (Cappel, ICN, Aurora, OH, USA) and/ or ... antibodies and JMAb23 were biotinylated using FluoReporter® Mini-biotin-XX Protein Labeling Kit (Invitrogen Japan K.K., Tokyo, Japan), in accordance with the manufacturer's instructions Biotinylation ... are defective in germinal centre formation, antibody productionand class switching in response to various antigens [13,47] The ICOS-B7RP-1 interaction in mice is involved in the initial clonal...
... exhausted in terms of IFN-α production These findings provide important insight into the pathogenesis of SLE and the markedly increased incidence of certain viral infections in SLE patientsIn addition, ... levels of IFN-α and CpG-induced IFN-α productionin vitro inpatientswith active SLE Interestingly, IFN-α production was completely abolished in PBMCs from one-third of SLE patients These data ... CpG-induced IFN-α productionin SLE PBMCs correlated inversely with SLE serum induced IFN-α productionin healthy PBMCs Also, SLE serum induced IFN-α productionin healthy PBMCs correlated with...
... CD28 and binds to CD80 and CD86 with a higher affinity Membrane bound CTLA-4 acts by interfering with CD28/CD80-CD86 interactions by competitive binding and also by mediating a negative signal interfering ... CTLA-4 transcripts in PBL The results obtained in SpA patients were compared with those obtained inpatientswith rheumatoid arthritis (RA) Materials and methods Patientswith spondylarthropathy ... Ankylosing Correlationand clinical index of disease T Lymphocyte Antigen- 4Spond(sCTLA-4) and clinical index of disease activity Bath Ankylosing Spondylitis Disease Activity Index in 165 patients with...
... ‘no pain’; mild, ‘pain’; moderate, ‘pain and winces’; severe, ‘pain; winces and withdraws’; and swelling rated as none, ‘no swelling’; mild, ‘palpable’; moderate, ‘visible’; and severe, ‘bulging ... using the following tenderness and swelling scales: tenderness rated as none, ‘no pain’; mild, ‘pain’; moderate, ‘pain and winces’; severe, ‘pain; winces and withdraws’; and swelling rated as none, ... seen with all canakinumab doses, with 24 to 67% of patients having no or mild pain by 24 hours post-dose (compared with 38% with triamcinolone acetonide), and reductions in pain in the canakinumab...
... albumin dialysis in significantly modifying the amino acid profile in primary biliary cirrhosis patientswith bilirubin, prothrombin index and albumin levels within normal ranges may sustain this ... acids decreased markedly inpatientswith alcoholic hepatitis and increased inpatientswith pruritus (Figure 1) Hence, the Fischer ratio increased significantly inpatientswith alcoholic hepatitis ... amino acid levels and the Fischer ratio were more prominent inpatientswith hepatic encephalopathy before treatment, baseline albumin concentration below 24 g/l, andin those in whom albumin...
... negative influence on respiratory and metabolic parameters inpatients not intubated Another recent study also indicated that delaying ALS in critically injured patients until arrival in the trauma ... Society of Intensive Care Medicine Intensive Care Med 1998, 24:1221-1225 Winchell RJ, Hoyt DB: Endotracheal intubation in the field improves survival inpatientswith severe head injury Trauma ... limited to one HEMS system, and the validity of our findings in other systems is, therefore, uncertain However, our finding that a large proportion of patientswith an indication for pre-hospital...
... vitamins A (retinol), D (cholecalciferol) and E (α-tocopherol) inpatientswith CAD MATERIALS AND METHODS The study population included 30 patients having angiographically demonstrated CAD and ... vitamins (retinol, tocopherol and cholecalciferol), and trace elements and heavy metals (Zn, Cu, Fe, Cd, Pb and Mn) inpatientswith CAD and the control group are shown in Table Compared with the ... increase in urine Cu levels inpatients suffering from myocardial infarction (MI) (15) Reunanen et al (1996) found increased levels of serum Cu inpatientswith CAD (14) In contrast, in our study,...
... CABG In the 11 patientswith vessel disease a stenosis > 50% was found in the circumflex artery inpatientsandin the right coronary artery inpatients Complete revascularization in the patients ... Int J Med Sci 2011, ability by the deformation indices two-dimensional strain (2DS) and strain rate (SR), might be an alternative approach in clinical routine Tissue Doppler Imaging (TDI) and ... 24-29 In principle, our findings are confirming previously published studies about infarct detection and size, who described significant differences of the radial and circumferential strain and...
... related increased oxidative activity in RA patients Anti-CCP antibodies are directed against antigens containing the nonstandard amino acid citrulline, for example, citrullinated fibrin, which ... from patientswith rheumatoid arthritis Clin Rheumatol 2000;19:275-277 29 Bandt MD, Grossin M, Driss F, Pincemail J, Babin-Chevaye C, Pasquier C Vitamin E uncouples joint destruction and clinical ... blood, serum and synovial fluid oxidant and anti-oxidant capacity inpatientswith RA Methods RA patientswith anti-CCP (+) (n=25) and anti-CCP (-) (n=24) were recruited into the study All patients...
... endoscopy in outpatients with iron deficiency anemia The aim of our study was to investigate the incidence of GI pathological findings in symptomatic and asymptomatic patientswith IDA and to identify ... deficiency patients could be fully investigated And, in 20% of patientswith IDA a routine upper and lower GI endoscopy may not ascertain GI cause during hospital admission [18] Cancer was diagnosed in ... gastrointestinal tract inpatientswith iron deficiency anemia N Engl J Med 1993; 329: 1691–5 29 Bini EJ, Micale PL, Weinshel EH Evaluation of the gastrointestinal tract in premenopausal women with...
... trimester in spite of no signs of threatened abortion Daily vaginal disinfection with popidone iodine, bed rest, and administration of ritodrine and an ulinastatin vaginal suppository were continued ... parametrium, and upper vagina through a vaginal approach and is designed to preserve child- bearing potential in young patientswith cervical cancer This procedure requires ligation and cutting the ... discussed Patientsand methods In the period from January 2003 through December 2009, a total of 20 women with early-stage invasive uterine cancer underwent vaginal RT with lymphadenectomy in Sapporo...
... their written informed consent Handedness was determined using a Chinese translation of the Edinburgh Handedness Inventory 29 Such an inventory has been used in two previous Chinese studies 30,31 ... were found in our study Discussion In the present study, patients scored higher on Neuroticism-Anxiety (with GAD patients scoring highest) and on depression (with TRD patients scoring highest) ... negatively correlated with the Disinhibition-Seeking score (n = 56, r = -.28, P < 05) in healthy subjects, andwith Total sensation-seeking (n = 47, r = -.30, P < 05) and Experience Seeking scores (n...