sesquiterpene lactones and parthenolide
Studies on the anti cancer potential of sesquiterpene lactone parthenolide
... Chemistry: sesquiterpene lactones and parthenolide Chemically, parthenolide belongs to the group of sesquiterpene lactone It was first isolated from feverfew in 1965 (Berry, 1984) Parthenolide ... glycosides and monoterpenes (Abad et al., 1995) The most predominant and well studied active component of feverfew is a group of sesquiterpene lactones such as parthenolide, costunolide and germacranolide, ... germacranolide, etc (Knight, 1995) These sesquiterpene lactones are enriched in the leaves and seeds of the feverfew which are believed to be produced by superficial leaf glands and act as general insect repellents...
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Human telomerase reverse transcriptase (hTERT) overexpression modulates intracellular redox balance and protects cancer cells from apoptotic cell death
... Prabha, Sajitha, and Vanitha thank you very much for you kindness, love and patience Thank you for the lifts and company that have made my hour and a half long journeys between campus and home seem ... peptidases (Anderson, 1998; Meister and Anderson, 1983) cysteine glycine glutamate Figure 4: Structure of Glutathione (Anderson, 1998) GSH is ubiquitously expressed in animal tissues, plants and micro ... enhance the antioxidant 25 system in the cells and protect them from ROS mediated cell death (Kowaltowski and Fiskum, 2005; LeGrand and Aw, 1998; Pias and Aw, 2002) 4.3.4 Glutathione Peroxidase Glutathione...
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Tài liệu Báo cáo khoa học: Competition between innate multidrug resistance and intracellular binding of rhodamine dyes pdf
... xenotoxins At the blood–brain barrier, and in placental trophoblasts, testis and bone marrow, it provides protection of vital body parts and, in the gut, liver and kidney, Pgp helps to eliminate ... [15–18] On the other hand, MRP1 is present in virtually all human tissues and in most human tumor cell lines and tumor samples [4] Using mice genetically deficient in both the mdr1a and mdr1b genes ... (circles), lM dye and 20 lM NBD-Cl (triangles) or lM dye and 50 lM MK571 (squares) Another cell sample was depleted of ATP by incubation in a medium containing CCCP and 10 mM deoxyglucose and in the...
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Tài liệu World Economic outlook - Financial Stress, Downturns and Recoveries ppt
... Inventories, and OPEC Spare Capacity 86 3.3 Grain and Oil Demand, Production, and Inventories in Comparison 87 3.4 Oil Supply Developments 95 3.5 Price Trends of Major Foods 97 3.6 Duration and ... 1980s and the 1990s, and in part because of policy shortcomings that have discouraged investment in new supply, for both energy and food With inventories low and spare capacity limited, and with ... supply and demand IMF staff has found some evidence that the depreciation of the U.S dollar and declining U.S interest rates have had an effect on prices through their impact on supply and demand...
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Tài liệu Báo cáo khoa học: Osmotic stress sensing and signaling in fishes doc
... sense and quantify changes in environmental salinity and to activate appropriate compensatory responses Thus, euryhaline fishes represent excellent models to identify and understand elements and ... including shark rectal gland [12] and teleost gill and opercular membrane [13] Full-length transcripts of CaSR have been cloned from gilthead sea bream (Sparus aurata) [13] and spiny dogfish (Squalus ... perception of concomitant fluid volume and ⁄ or blood pressure changes Systemic osmosensors and baroreceptors are responsible for monitoring plasma osmolality and they are conserved in all vertebrates...
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Tài liệu Báo cáo Y học: Regulated expression and intracellular localization of cystatin F in human U937 cells pptx
... four-band pattern at SDS/PAGE (Fig 1) At comparison with insect cell produced recombinant cystatin F (Fig 1, lanes and 2), which appears as one mono- (band B) and one di-glycosylated (band A) ... nuclei and cell debris), a heavy and a light fraction containing mitochondria and various cell organelles, and a supernatant containing the smallest cellular vesicles Cystatin F, cystatin C and ... were rinsed in · NaCl/ Cit and washed in · NaCl/Cit and 0.1% SDS for 45 at room temperature; 0.2 · NaCl/Cit and 0.5% SDS for 45 at room temperature; 0.2 · NaCl/Cit and 0.5% SDS for 30 at 50 °C...
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Stress symptoms and coping strategies in healthy elderly subjects pot
... assessment comprises two (primary and secondary) interdependent stages and consists in a process that defines why and to what extent a certain relation between individuals and the environment that surrounds ... However, the mechanisms inherent to the stress re- tween demands and efforts made to act upon them is called sponse, organized to prepare and protect the organism coping(6) The current definition ... compared to young their resources and endangering their wellbeing(6) This adults, the association between coping style and stress appraisal process of the stress event and the individual re- symptoms...
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Báo cáo khoa học: Critical roles of Leu99 and Leu115 at the heme distal side in auto-oxidation and the redox potential of a hemeregulated phosphodiesterase from Escherichia coli pptx
... the Leu99 and Leu115 mutant and wild-type proteins differed significantly A possible explanation for these findings is that O2 and CO have different modes of ligand binding but share a ligand access ... are His77 and Met95 In addition, the FG loop is very flexible and disordered and could not be resolved in the crystal structural for the Fe(III) heme complex, whereas the loop was rigid and could ... (SmFixL), and Ile238 (BjFixL) ⁄ Val232 (SmFixL) for BjFixL and SmFixL, there is no amino acid that spatially corresponds to Ile215 (BjFixL) ⁄ Ile209 (SmFixL) in Ec DosH (Figs and 2) [10] Phe113 and...
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Báo cáo Y học: A Ca2+/CaM-dependent kinase from pea is stress regulated and in vitro phosphorylates a protein that binds to AtCaM5 promoter ppt
... Engineering and Biotechnology and funds from Department of Science and Technology, Government of India We thank Prof S Assmann for critical reading of the manuscript and constructive suggestions and ... stress (0.3 M NaCl) and osmotic stress (0.3 M mannitol) for 24 h and roots and shoots were harvested separately Extracted proteins were separated by SDS/PAGE (25 lg per lane) and probed with anti-ZmCCaMK ... (v/v) and collected by gentle centrifugation Nuclei were resuspended in washing buffer containing 110 mM KCl, 10 mM phenylmethanesulfonyl fluoride, and lgÆmL)1 each of antipain and leupeptin and...
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Báo cáo khoa học: Relaxin-3⁄ insulin-like peptide 7, a neuropeptide involved in the stress response and food intake Masaki Tanaka pptx
... pars compacta and pars dissipata, and relaxin-3positive neurons are found in both regions (Fig 1A) With reference to the distribution of relaxin-3-positive nerve fibers and RXFP3 and RXFP1 expression, ... expression and function in the hypothalamus sion and leads to an increase in relaxin-3 mRNA levels in the NI [12] On the other hand, relaxin-3-positive neurons project fibers to the hypothalamus, and ... 24 Osheroff PL & Ho WH (1993) Expression of relaxin mRNA and relaxin receptors in postnatal and adult rat brains and hearts Localization and developmental patterns J Biol Chem 268, 15193–15199...
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oxidative stress biomarkers and antioxidant protocols
... 18 Browne and Armstrong Fig Simultaneous chromatograms of LHP and LOH standards at 236 nm (A) and native unoxidized PUFA standards at 25 nm (B) See Subheading 3.3 for HPLC conditions and Table ... Methods and Protocols, edited by Tanja Zigova, Juan R Sanchez-Ramos, and Paul R Sanberg, 2002 197 Mitochondrial DNA: Methods and Protocols, edited by William C Copeland, 2002 196 Ultrastructural and ... Bing-Yuan Chen and Harry W Janes, 2002 191 Telomeres and Telomerase: Methods and Protocols, edited by John A Double and Michael J Thompson, 2002 190 High Throughput Screening: Methods and Protocols,...
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báo cáo hóa học: " Occurrence of post traumatic stress symptoms and their relationship to professional quality of life (ProQoL) in nursing staff at a forensic psychiatric security unit: a cross-sectional study" potx
... CL, TP and KN conceived and designed the study CL collected the data CL and TP performed statistical analysis and drafted the manuscript All authors revised the manuscript critically and approved ... (BO) and Compassion Fatigue (CF) was in all four wards reported well below average scores according to normative data in the ProQOL manual (Figure and Figure 3) Total mean BO was 17.3 (SD 4.4) and ... quartiles and extreme values for Box plot indicating median, quartiles and extreme values for scores on CS at the different wards Horizontal dotted lines indicate bottom quartile, median and top...
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báo cáo hóa học: " Prevalence of stress, anxiety and depression in with Alzheimer caregivers" ppt
... relationships within the family and in the workplace) and emotional burden (negative feelings towards the patient) [11] It is easy to complete and simple to understand The interviews, in the present ... interviewed, 29% claim to be unable to accept the situation and wish to abandon their home Mean values of MMSE, ADL and IADL of the patients and CBI of the caregivers are outlined in Table At the ... psychological condition, and, therefore, anxiety and depression of the caregiver, are closely related to the values of the MMSE, ADL, IADL and to the several phases of the cognitive and physical deterioration...
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báo cáo hóa học:" Psychosocial stress, demoralization and the consumption of tobacco, alcohol and medical drugs by veterinarians" ppt
... working hours and the number of years of professional work • „Over the past few years, my job has become more and more demanding.“ (ERI6) • „During my work I am afraid of injuries and infections.“ ... Jeyaratnam J, Jones H, Phillips M: Disease and injury among veterinarians Aust Vet J 2000, 78:625-629 Landercasper J, Cogbill TH, Strutt PJ, Landercasper BO: Trauma and the veterinarian J Trauma 1988, ... two-day-coaching to reduce stress and to increase traffic safety for veterinarians, initiated by the Institution for Statutory Accident Insurance and Prevention in the Health and Welfare Services [17]...
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báo cáo hóa học: " Quality of life in Croatian Homeland war (19911995) veterans who suffer from post-traumatic stress disorder and chronic pain" doc
... contributions MB and VD conceived the study and provided the research idea; VM, LBie < and MB performed clinical work and surveyed the patients; MB, OP and VB performed the analysis, MB, VB and OP drafted ... association, and that the diagnosis is just one part of the QOL and PTSD with LBP group Nevertheless, there were some exceptions, suggesting that the measurement and estimation of QOL and its association ... Homeland war (1991-1995) veterans who suffer from post-traumatic stress disorder and chronic pain Health and Quality of Life Outcomes 2011 9:56 Submit your next manuscript to BioMed Central and...
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Stress, Strain, and Structural Dynamics ppt
... professionals and students with a comprehensive and definitive reference to statics and dynamics of solids and structures The book is for use as a resource and design tool in research and development, and ... the table, wo and ui are transverse boundary displacements, #0 and OL rotations, Mo and ML moments, and Qo and Qi transverse forces The positive direction of boundary displacements and transverse ... in many courses And for instructors, the book offers an easy and efficient approach to curriculum development and teaching innovation Uniqueness This book differs from standard handbooks in that...
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Tài liệu tiếng anh tham khảo stress coping and health
... uncertainty and ambiguity; proximity (time and space), intensity, and duration of the threat; and the controllability of the threat What occurs during appraisal processes determines emotions and coping ... medicine’s social mandate has been the diagnosis and treatment of disease Public health professionals and government agencies commonly adopt the biomedical model and use morbidity and mortality statistics ... stress, coping, and health This chapter has provided a historical overview of stress, coping, and health and its importance for the profession and discipline of nursing References Alexander, F (1950)...
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Devaluation and the trade balance
... many other combinations of fall in foreign prices and fall in demand T h e same considerations hold for ioreigners' demand for the domestic currency and, therefore, for the supply of foreign eschanqe ... adopt the following notation: I and E are the values of imports and of exports of the devaluing country expressed in foreign exchange I' and E' are the same imports and exports expressed in domestic ... d o ~ ; n ~ a rsloping d demand functions for foreign exchange (imports) and domestic currency (exports) (1) (2) I E' = f(r) = g(rf) 51 and (b) the corresponding demand elasticities (3) (4) -...
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Báo cáo sinh học: " Genome degeneration affects both extracellular and intracellular bacterial endosymbionts" pot
... transcriptional regulators, and recombination and DNA repair factors, and high mutation rates [6-8] Similar genomic features are also observed in pathogens, including Mycoplasma species and obligate intracellular ... intra- and extracellular endosymbionts, future genome analysis of Ishikawaella and Rosenkranzia will reveal whether there are basic differences in the gene pools retained between extraand intracellular ... dynamics and time scale of ongoing genome erosion in symbiotic bacteria Science 2009, 323:379-382 Attardo GM, Lohs C, Heddi A, Alam UH, Yildirim S, Aksoy S: Analysis of milk gland structure and function...
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Báo cáo sinh học: " Oxidative stress, thermogenesis and evolution of uncoupling proteins" doc
... Biology 2009, Volume 8, Article 58 Rial and Zardoya hibernating and newborn mammals Interestingly, in the Suidae (pigs and wild boars), the UCP1 gene is disrupted, and therefore piglets have poor thermoregulation ... into UCP1 and the common ancestor of UCP2-3, which subsequently duplicated into UCP2 and UCP3 Each of the three paralogs is found in fish, amphibians, and mammals Strikingly, UCP1 and UCP2 have ... Science and Innovation to ER (BFU2006-08182 and Consolider-Ingenio 2010 CSD2007-00020) and RZ (CGL2007-60954) Due to journal policy, we have only sparingly referenced the literature and apologize...
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