selection of an experimental animal model
Báo cáo sinh học: " Respiratory syncytial virus-induced acute and chronic airway disease is independent of genetic background: An experimental murine model" pot
... acute and long-term effects of RSV infection, as suggested by the higher rates of RSV hospitalization among Native American and Alaskan Native children compared with other groups [6] Animal models ... conducted Sample collection Mice were anesthetized with an intraperitoneal injection of 75 mg/kg of ketamine and mg/kg of acepromazine before euthanasia by exsanguination On average, 4–12 mice were ... = number of samples analyzed Spearman's rank order analysis was used Statistically significant correlations (p < 0.05) listed in bold font N/A, not applicable, samples from different animals;...
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Báo cáo khoa học: "Absence of vertical transmission of Helicobacter pylori in an experimental murine model" ppt
... eht ot trofmocsid ro niap eziminim ot edam erew stroffe llA )aeroK ,luoeS( ytisrevinU lanoitaN luoeS fo eettimmoC esU dna eraC laminA lanoitutitsnI eht yb devorppa dna ytisrevinU lanoitaN luoeS ... ehT yreviled litnu rof derac erew slibreg tnangerp eerht rehtona ,noitidda nI noitcefni irolyp H rof dezylana dna detalosi erew sesutef dna rehtom eht fo selpmas cirtsag ehT ycnangerp retfa skeew ... o o o o o o etanegomoh evoba eht morf detcartxe saw AND lairetcab ehT noitcaer niahc esaremyloP erudecorp RCP gniwollof eht rof desu saw etanegomoh gniniamer eht ,noitcefni irolyp H mrifnoc ot...
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Báo cáo y học: "Reliability of continuous cardiac output measurement during intra-abdominal hypertension relies on repeated calibrations: an experimental animal study" ppsx
... Scatter plots and Bland–Altman plots pooled data pairs Scatter plots and Bland–Altman plots of of pooled data pairs Scatter plots (left-hand side) and Bland–Altman plots (right-hand side) of pooled ... percentage change of each CO method and was plotted against ΔCOTCP using linear regression and Bland–Altman analysis P < 0.05 was considered statistically significant Results Nine animals were ... results of Bland–Altman analysis comparing COTCP and different CO methods at each individual step, Figure S1 showing linear regression and Bland–Altman plots comparing changes in CO (ΔCO) of different...
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Báo cáo y học: "Understanding the cognitive consequences of critical illness through experimental animal models" pps
... 13 No Gunther and English models of higher level cognition and behavior are being developed The hope is that these may help bridge the gap between bench research and bedside care Experimental ... investigations that incorporate the ability to assess subtle changes in animal cognition offer great promise for advancing our understanding ICU acquired long-term cognitive impairment Competing ... Discrimination of what, when, and where: Implications for episodic-like memory in rats Learning Motivation 2005, 36:177-189 Crystal JD, Maxwell KW, Hohmann AG: Cannabinoid modulation of sensitivity...
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báo cáo hóa học:" Bone quality and growth characteristics of growth plates following limb transplantation between animals of different ages - Results of an experimental study in male syngeneic rats" potx
... reconstruction of bony defects and restoration of longitudinal growth The performance of limb transplants between male syngeneic Lewis rats of different ages constitutes a unique experimental model, and ... the bone quality of transplanted allogenic bone from the donor The results of the above experiment suggest that even after transplanting the limbs of juvenile animals into adult animals (heterochronografts), ... quality and growth characteristics of growth plates following limb transplantation between animals of different ages - Results of an experimental study in male syngeneic rats Journal of Orthopaedic...
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Báo cáo lâm nghiệp:" How to relate the standing tree shape to internal wood characteristics: Proposal of an experimental method applied to poplar trees" pptx
... Measurement of tree shape 375 Figure Illustration of the three levels of shape analysis for tree FV1: (A) skeleton of the standing tree; (B) reconstruction of the tree shape and of the sampled ... accuracy of tree reconstruction is the measurement of the targets on the standing tree An experiment was carried out to quantify the precision of an operator when targets were measured by means of ... the previous phase for a set of angular positions, for instance 36 positions corresponding to an angular step of 10°, a discrete description of the external shape of the log was achieved The corresponding...
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Báo cáo khoa học: "Efficacy and safety of a low-flow veno-venous carbon dioxide removal device: results of an experimental study in adult sheep" pps
... has the disadvantages of an increased bleeding risk (even if reduced after the introduction of percutaneous cannulation techniques and heparin-coated circuits) and the requirement of specialised ... Our study was designed to evaluate the efficacy and safety of a veno-venous CO2 removal device in an animal model By using an EBF of up to 5% of cardiac output, we succeeded in reducing PaCO2 ... experiments and data acquisition MV conducted experiments, interpretation of data, and manuscript drafting GB performed study conception and design, statistical analysis and interpretation of data, and...
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Báo cáo sinh học: "Assessment of a Poisson animal model for embryo yield in a simulated multiple ovulation-embryo transfer scheme" potx
... men with balanced Robertsonian translocation between chromosomes 13 and 14 (Luciani et al, 1984) and 14 and 21 (Rosenmann et al, 1985) In all of the micrographs observed, the phase of unpairing ... JM, Guichaoua MR, Mattei A, Morazzani MR (1984) Pachytene analysis of a man with a 13q;14q translocation and infertility: behaviour of the trivalent and nonrandom association with the sex vesicle ... microscopic (em) analysis of synaptonemal complexes (SC) in the meiotic cells of domestic animals carrying chromosomal aberrations began with the works of Switonski et al (1987) and Gabriel-Robez...
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Báo cáo sinh học: " Assessment of a Poisson animal model for embryo yield in a simulated multiple ovulation-embryo transfer scheme" pot
... estimates of fixed effects and predictions of random effects in the linear model analysis; for the Poisson model, the true values of the variance components were used Empirical biases and MSEs of the ... value can then be interpreted as the expected value of the Poisson parameter of an observation made under the conditions of an ’average’ level of the fixed effects and in the absence of random ... H!&dquo; RESULTS AND DISCUSSION One-way model Means and standard procedures are given &dquo;) ( errors of estimates of the genetic variance for the five in table II and MSEs of the estimates...
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Báo cáo sinh học: " Application of a haematopoetic progenitor cell-targeted adeno-associated viral (AAV) vector established by selection of an AAV random peptide library on a leukaemia cell line" pot
... pri(EARVRPP;100 mary human) CMLaand CD34rAAV2-based GFP+ cells) using Figure of and standard + rAAV capsid mutant an MOI Gene transfer efficiency of the rAAV capsid mutant (EARVRPP; ) and a standard rAAV2-based ... were harvested and analysed Page of (page number not for citation purposes) Genetic Vaccines and Therapy 2008, 6:12 Acquisition and analysis For acquisition and analysis of the gene transfer data, ... Vaccines and Therapy 2008, 6:12 http://www.gvt-journal.com/content/6/1/12 Figure MOI of 100 using an Gene transfer efficiency of the rAAV capsid mutants and control vectors on a panel of leukaemia...
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Characterization of CMX 13 and evaluation of efficacy and mechanisms of action in animal model of autoimmunity
... been tested in animal models of organ transplantation Berbamine, an alkoloid from the plant, Berberis juliane, has been demonstrated to have anti-hypertensive, anti-arrthymic and immunosuppressive ... Quantification of IFN-γ mRNA transcripts by quantitative real-time PCR Quantification of IL-6 mRNA transcripts by quantitative real-time PCR Quantification of IL-6 mRNA transcripts by quantitative ... years, the use of TCM as immunosuppressive agents has been studied in-vitro and in-vivo in various experimental animal models of autoimmune diseases and allograft transplant Moreover, experimental...
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Báo cáo sinh học: "Univariate and multivariate parameter estimates for milk production traits using an animal model. II. Efficiency of selection when using simplified covariance structures" docx
... Implementation of an animal model for genetic evaluation of dairy cattle in the United States J Dairy Sci 71 (suppl 2) 54-69 Wiggans GR, Misztal I, Van Vleck LD (1988b) Animal model evaluation of Ayrshire ... Univariate and multivariate parameter estimates for milk production traits using an animal model I: Description and results of REML analyses Genet Sel Evol, 24, 415-430 Wiggans GR, Misztal I, Van Vleck ... multivariate analysis on traits When using the canonical variates there was no advantage of a MV analysis over an analysis with a repeatability model is slightly , 11 (M F Analysing linear combinations of...
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An experimental study on the thermal valorization of municipal and animal wastes
... co-firing of RDF and coal Waste Management 2010, 30, 1334-1340 Kirubakaran V., Sivaramakrishnan V., Premalatha M., Subramanian P Kinetics of AutoGasification of Poultry Litter Int J of Green energy ... Figure Experimental and calculated DTG profiles of PW pyrolysis experimental calculated DTG (%/min) 200 300 400 500 600 700 o Temperature ( C) Figure Experimental and calculated DTG profiles of RDF ... produce heat and power Rather than being a problem of waste, poultry litter and RDF can and should be a source of energy The results can aid the proper design of boilers and furnaces using such fuels...
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Báo cáo khoa học: Natriuretic peptide system: an overview of studies using genetically engineered animal models doc
... Role of ANP- and BNP-mediated GC-A signaling in blood pressure regulation Transgenic animals, which constitutively express a fusion gene consisting of the transthyretin promoter and the ANP gene, ... exons 1–13 and an additional 3.8 kb of the 5¢ sequence of the GC-A gene, a loxP-flanked neomycin resistance cassette (at )2.6 kb of exon 1) and a third loxP site in the middle of intron Dominant-negative ... half of the extracellular ligand-binding domain and the transmembrane segment, were replaced by the neomycin resistance gene Most of exon was replaced by the neomycin resistance gene GC-B dominant...
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báo cáo hóa học: " Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression" docx
... of rats exposed to an animal model of depression This activation occurs with increased levels of the pro-inflammatory cytokine IL-1b and of one of the main enzymatic sources of inflammatory and ... acquisition, analysis and interpretation of CMS model and behavioural data; JAM and JRC revised the manuscript critically; and JCL contributed to conception and design, drafting the manuscript and revising ... induction of COX-2 in the CNS by stress and the increase in the PGE levels in the brain cortex are well documented phenomena [48,49] of significant importance in experimental models of depression and...
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báo cáo hóa học:" Establishment of an animal model of a pasteurized bone graft, with a preliminary analysis of muscle coverage or FGF-2 administration to the graft" potx
... osteoclastogenesis and angiogenesis [17] In the current study, during the course of the establishment of a pasteurized bone model in rats, a preliminary analysis of the effect of the presence of muscle-covering ... osteoprogenitor cells, and it plays an important role in bone metabolism and in the regulation of osteoblastic cell proliferation and differentiation [13-16] Furthermore, FGF-2 also plays an important role ... graft matrix [5] Other advantages of the method include a precise anatomical fit, and no risk of disease transmission or immunological reaction [4-10] Regardless of such advantages, clinical problems,...
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Báo cáo y học: "Genetic control of disease in an experimental model for Sjögren’s syndrome Åsa Andersson" potx
... Vol 11 No Andersson lapping Aec2 intervals The recombinant inbred mice were subsequently investigated for SjS disease phenotypes: saliva production, sialadenitis, and anti-nuclear antibodies ... 10 centiMorgans (cM), located 80 cM from the centromere on chromosome [1] Dissections of disease loci in models for autoimmune diseases have shown that one locus can contain more than one gene ... Aec2 locus, important in the homeostasis of lipids, lipoproteins, cholesterols, and fatty acids Secondary effects of impaired lipid homeostasis could result in inflammation and cell death Results...
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Báo cáo y học: "Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis" pptx
... and immunohistological preparations, and helped to draft the manuscript MAC performed animal surgery and helped to draft the manuscript RAR performed animal surgery and helped to draft the manuscript ... authors thank Diana Pethick of Murdoch University for her assistance with the animal handling and care 22 Maroudas AI: Balance between swelling pressure and collagen tension in normal and degenerate ... significant Western blotting of the small leucine-rich proteoglycans Western blot analysis of extracts of an equivalent dry weight of pooled LTP cartilage from control and meniscectomized joints and...
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