role of vitamin c and vitamin e in periodontal disease
Báo cáo y học: " The role of vitamin D in pulmonary disease: COPD, asthma, infection, and cancer" ppsx
... synthesis and secretion is induced by decreased serum calcium levels, which are detected by the calcium sensing receptor of the parathyroid gland PTH effects renal tubular reabsorption of calcium, renal ... pathogens are detected in about 50% of exacerbations A therapeutic consequence would be the up-regulation of the innate immune defense system Wang and colleagues demonstrated that genes coding ... Asthma A connection between VitD status and asthma has been considered since many years VitD deficiency has been blamed as one cause of increased asthma prevalence in the last decades [60] VDR...
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Báo cáo khoa học: Role of glutaredoxin 2 and cytosolic thioredoxins in cysteinyl-based redox modification of the 20S proteasome docx
... disulfide bonds in the ribonucleotide reductase of thioredoxin-deleted Escherichia coli strains [14] Since then, biochemical and genetic approaches have provided evidence for a protective role of ... the molecular architecture of Grx2 consists of a four-stranded, mixed b-sheet and five a-helices The b-sheet forms the central core of the protein, with helices and located on one side of the ... we determined that only a few cysteine residues among the total of 72 are exposed to the environment: 10 solvent-accessible cysteines were determined to be present on the surface, with some of...
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báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pptx
... treated cells As seen in Figure and Table 3, BMP-2 treatment enhances mineralization of the cells as shown by uptake and presence of Alizarin Red after cultures were grown to confluence and then ... “Ct gene T” represents the calculated threshold cycle (C t ) of a time point of each sample other than hr, or each treatment other than control Relative gene absolute abundance was calculated using ... the relative FGF-2 regulation and sequential expression of growth, angiogenic and chemotactic genes and depresses expression of mineralization-related genes, these figures not tell us the relative...
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báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pdf
... treated cells As seen in Figure and Table 3, BMP-2 treatment enhances mineralization of the cells as shown by uptake and presence of Alizarin Red after cultures were grown to confluence and then ... “Ct gene T” represents the calculated threshold cycle (C t ) of a time point of each sample other than hr, or each treatment other than control Relative gene absolute abundance was calculated using ... the relative FGF-2 regulation and sequential expression of growth, angiogenic and chemotactic genes and depresses expression of mineralization-related genes, these figures not tell us the relative...
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Báo cáo khoa học: "Overexpression of cyclin D1 and cyclin E in 1,2-dimethylhydrazine dihydrochloride-induced rat colon carcinogenesis" potx
... suggest that there was no specific association between the overexpression of cyclin D1 or cyclin E with PCNA, and that cyclin D1 and cyclin E overexpression occurred independently of PCNA These ... cyclin E overexpression and the clinicopathologic factors of colorectal cancer [2, 18] Further investigation is needed to determine whether the altered expressions of cyclin D1 and cyclin E can be ... results also suggest that the overexpression of either cyclin D1 or cyclin E is not a mere consequence of cellular proliferative activity, but rather represents a true difference between the...
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Báo cáo y học: " Role of miR-1 and miR-133a in myocardial ischemic postconditioning" pptx
... used for quantitative real-time RT-PCR RT-primers 5’-GGCTGCCGACCGTGTCGTGGAGTCGGCAATTGGTCGGCAGCCATACACAC-3’ miR-133a 5’-GTCGTATCCAGTGCAGGGTCCGAGGTATTCGCACTGGATACGACACAGCT-3’ miR1-F 5’-CTGTCACTCGAGCTGCTGGAATG-3’ ... (ischemia 30 sec/reperfusion 30 sec) were given just before reperfusion This sample size was chosen based upon the results of a power analysis Infarct size measurement Infarct size of the myocardium ... final manuscript Competing interests The authors declare that they have no competing interests Received: 29 November 2010 Accepted: 16 March 2011 Published: 16 March 2011 References Cokkinos DV,...
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Báo cáo y học: "The role of mast cells and fibre type in ischaemia reperfusion injury of murine skeletal muscles" pot
... ischemia period, the bands were removed and the mice allowed to recover After 24 h reperfusion the mice were re-anaesthetized and the gastrocnemius, soleus and EDL muscles were carefully removed ... mast cell therapies would be beneficial across different muscle types and that further protection can be tailored to specific muscle types It is clear that mast cell depleted mice are the desirable ... papers will be: available free of charge to the entire biomedical community peer reviewed and published immediately upon acceptance cited in PubMed and archived on PubMed Central yours — you keep...
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Báo cáo y học: "Role of contractile prostaglandins and Rho-kinase in growth factor-induced airway smooth muscle contraction" ppt
... papers will be: available free of charge to the entire biomedical community peer reviewed and published immediately upon acceptance cited in PubMed and archived on PubMed Central yours — you keep ... the contractile effects of EGF and PDGF on guinea pig tracheal smooth muscle, CRCs of the growth factors were constructed (Fig 1) Both EGF and PDGF were capable of inducing concentration-dependent ... smooth muscle; COX, cyclooxygenase; cPLA2, cytosolic phospholipase A2; CRC, cumulative con- centration response curve; EGF, epidermal growth factor; EP1-receptor, prostaglandin E2 -receptor type 1;...
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Báo cáo y học: " The role of cyclin D2 and p21/waf1 in human T-cell leukemia virus type 1 infected cells" potx
... Nurse, Cancer Research UK Your research papers will be: available free of charge to the entire biomedical community peer reviewed and published immediately upon acceptance cited in PubMed and archived ... Time Figure Increased levels of cyclin E/ cdk2 kinase activity in HTLV-1 infected cells Increased levels of cyclin E/ cdk2 kinase activity in HTLV-1 infected cells (A) Seventy-five micrograms of ... overexpressed and are in a stable kinase active complex in HTLV-1 infected cells Cell cycle regulatory genes are often targeted in tumorigenesis mainly due to their direct involvement in deregulating...
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Báo cáo y học: "The contemporary role of blood products and components used in trauma resuscitation" pdf
... patients Initial blood samples in this study were obtained at accident scenes and in the Emergency Department Overall, little difference was seen in TEG parameters between the accident scene and ... Patients receiving uncrossmatched red blood cells in the Emergency Department were more than three times more likely to receive early massive transfusion of red blood cells These authors recommend considering ... component replacement during severe hemorrhage Replacement options were offered in the model and their effectiveness evaluated [11] In the computer model, an intravascular compartment was created...
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the role of ikkalpha, ikkbeta and nf-kappab in the progression of breast cancer
... Inhibition decreases expression of NF-κB regulated genes, which have been implicated in pancreatic cancer such as cyclooxygenase-2 [129] Colorectal cancer tumours have increased activity of the p65 ... development of many effective therapies, there remains a need for novel therapeutics for TNBC and for patients who have developed endocrine resistance In order to so, the mechanism of recurrence ... resistance has occurred Further examination of the pathways in breast cancer cell lines also demonstrated a difference between ER positive and ER negative breast cancer In ER negative MDA-MB231 cells...
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Blogging and collective action the role of collective identity and social networks in engendering change
... clarify key dimensions of collective identities experienced by movement participants To reiterate, the theories and research reviewed in the preceding sections reveal that RM perspectives typically ... informal ties were more successful than face-to-face street recruitment efforts in the case of the Nichiren Shoshu movement Eighty two percent of the members (n=345) were recruited through pre-existing, ... 1993) defined collective incentives as the value of goals as well as one’s expectation of the movement’s success He further broke the theoretical construct down into three components: one’s expectations...
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The role of NF kb and histone deacetylase in gene regulation
... Dulbecco’s modified eagle’s medium DMBA/TPA 7, 12-dimethylbenz (a) anthracene/12-Otetradecaroylphorbol-13-acetate ECL Enhanced chemiluminescence EDTA Ethylenediamine tetraacetic acid EGTA Ethyleneglycol ... intermediate players to relay the message from the cell surface to the internal of the cell to activate the IKK complex TNF receptors are present on the surface of a wide range of cells, and use ... and the overexpression of PP 2C decreases NFκB directed gene expression The overexpression of PP 2C reduced the resynthesis of IκBα, a target gene of NF-κB, and affected the phosphorylation of...
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The role of nitric oxide and prostaglandin e2 in prolonged hemorrhagic shock 2
... pressure in the presence of a decrease in circulating blood volume and a modest decrease in cardiac output Some of the regulatory mechanisms include cerebral ischemic responses, reabsorption of ... lesion volumes, in cubic millimeters, were calculated by the integration of the distance of the chosen sections The presence of cerebral edema was corrected by dividing the total lesion volume ... gastrointestinal consequences of shock include increased acid production and increased permeability of the gastric mucosa The increased permeability allows tissue penetration by acids, bacteria and endotoxins...
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The role of nitric oxide and prostaglandin e2 in prolonged hemorrhagic shock 1
... Histological findings showed increased numbers of hyperchromatic and shrunken cortical neurons in salinetreated FPI+HS, FPI or HS rats Decreased MABP and percentage cerebral tissue perfusion (CTF) were ... Figure Legend Figure 2.1 Untreated rats showed significant decrease in percentage 17 survival when compared to sham-operated rats Figure 2.2 Untreated rats showed significant decrease in mean arterial ... treatment groups Nitrate/nitrite level, glutamic oxalacetic transaminase (GOT) level and creatinine level (an indicator of liver and renal damage respectively) were also significantly improved in...
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Quantification of vitamin e and ç oryzanol components in RiceGermandBran
... the cleavage of the side chain accompanied by the breakdown of the chroman structure with a hydrogen rearrangement and the loss of a methyl acetylene (CH3-CtCH) fragment (Figure 3) CID of deprotonated ... MS peak areas of IS to the LC-MS/MS analyses Calibration curves of each standard were created from seven concentrations using Microsoft Excel software The concentrations of individual components ... under reduced pressure at room temperature until ethanol and methanol were removed followed by drying in a freeze-dryer The dry extracts (extractable phytochemicals) represented 24.8% of the rice...
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Báo cáo y học: "A systematic review of the role of vitamin insufficiencies and supplementation in COPD" docx
... b-carotene, and vitamin supplements Further articles were identified from the reference lists of the included articles In order to be as accurate as possible we included in the present review ... advantages and disadvantages Serum levels of vitamins The assessment of serum levels of vitamins can have the advantage of being more objective than patient’s Page of reported intake However, serum ... supplementation, for 5-8 years 29.133 people (Cancer prevention study) The supplementation did not affected the reccurence or incidence of chronic cough, phlegm or dyspnea Relative risk for the...
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In vitro and in vivo study of vitamin e TPGs coated immunoliposomes for sustained and targeted delivery of docetaxel
... bioavailability of various anticancer drugs Docetaxel (DTX) has been known to have excellent therapeutic effects for a wide spectrum of cancers such as breast cancer, ovarian cancer and head and neck cancer ... cancer Since the discovery of chemotherapeutic drugs for cancer, many challenges have been raised due to the systemic toxicity and adverse side effects caused by these drugs (Feng and Chien, 2003) ... http://www.cancer.gov/cancertopics/cancerlibrary/what-is-cancer http://cancerhelp.cancerresearchuk.org/about-cancer/what-is-cancer/cells/the-cancer-cell http://news.bbc.co.uk/2/hi/health/3444635.stm 7 In cancer,...
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Tài liệu Báo cáo khoa học: Unfolding of human proinsulin Intermediates and possible role of its C-peptide in folding/unfolding pptx
... according to the reference [36] The molecular mass of the disulfide isomers of HPI and the enzyme-digested fragments were measured by ESI MS The molecular mass of the mixture of scrambled isomers ... the disulfide bonds more accessible Experimental procedures Materials Recombinant HPI and PIP were of > 98% purity as confirmed by RP-HPLC on a C8 column Endoproteinase Lys -C and V8 were of sequencing ... disulfide bonds of the scrambled isomers could be readily reduced by a low concentration of reductive reagents, and intermediates with heterogeneous disulfide bonds could then be observed during...
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Báo cáo khoa học: Role of the C-terminal extension in a bacterial tyrosinase Michael Fairhead and Linda Thony-Meyer doc
... tyrosinase has been reported not to require a copper chaperone for activity [12] Given their interesting properties and the wide potential of these enzymes, there are few successful examples of recombinant ... tyrosinase, which also has been reported not to require a copper chaperone [12] The presence of another multicopper oxidaselike laccase gene upstream of the tyrosinase gene is also interesting because ... samples were incubated for 24 h at room temperature prior to fluorescence measurements The fluorescence of each sample was subsequently measured on a Cary Eclipse spectrofluorimeter (Varian Inc.)...
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