rns mediated oxidation and failing degradation turnover foster production of autoantibodies in vitiligo
Báo cáo y học: " Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo" pot
... expression of at least 60% Distribution of asODN and siRNA in the murine nose in vivo Inefficient transfection of airway epithelial cells may be a key limiting factor in achieving meaningful levels of ... treatment of a variety of lung diseases including asthma and other pulmonary inflammatory diseases and have shown some efficacy in pre-clinical models after nebulisation, intratracheal injection, intravenous ... 10 In vitro screening of ENaC asODN in M1 cells In vitro screening of ENaC asODN in M1 cells M1 cells were transfected with different αENaC asODN and a control ODN complexed to Lipofectamine...
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Báo cáo y học: " Polysaccharides from the root of Angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice
... prescription of TCM containing AP, was shown to protect mice against hydrocoticoid-induced inhibition of IFN-γ, IL-2, IL-4 and IL-10 transcription [24] In addition, vitamin B12, folinic acid and biotin ... effects of a Traditional Chinese Medicine, You-Gui-Wan, on steroidinduced inhibition of cytokine production in mice Int Immunopharmacol 2005; 5: 1041-8 25 Huang KC The Pharmacology of Chinese Herbs ... Use of Live Animals in Teaching and Research of the University of Hong Kong Male ICR mice (weighing 25–30 g) were reared on a standard laboratory diet (Ralston Purina, Chicago, Illinois, USA) and...
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Tài liệu Gulf War and Health: Volume 4. Health Effects of Serving in the Gulf War docx
... of Engineering was established in 1964, under the charter of the National Academy of Sciences, as a parallel organization of outstanding engineers It is autonomous in its administration and in ... principal operating agency of both the National Academy of Sciences and the National Academy of Engineering in providing services to the government, the public, and the scientific and engineering ... weapons in fighting Iran and in attacks on the Kurdish minority in Iraq Military leaders feared that the use of such weapons in the gulf could result in the deaths of tens of thousands of Americans...
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Báo cáo lâm nghiệp: "of morphological characters and molecular markers for the analysis of hybridization in sessile and pedunculate oak" pps
... letswaart and Feij, 1989) Interspecific gene flow between sessile and pedunculate oak has been inferred in many studies on the basis of the finding, in natural mixed populations, of trees with intermediate ... ses/ses and ped/ped were considered as principal points, and individuals of the mixed zones ped/ses and ses/ped as supplementary points (DFAb) In the third DFA, only characters independent of the ... characters in one given species, and the studies of hybridization These errors could be reduced in size only by means of the comparison of the distribution of many kinds of characters and of genetic...
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Báo cáo y học: "Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium" potx
... signalling level proteins capable of inhibiting caspase activation, such as FLIP (flice inhibitory protein) [11], that blocks initiator caspase (caspase-8) and IAP (inhibitor of apoptosis protein) ... Characteristics of patients are summarised in Table Clinical and laboratory data were collected from all RA patients including tender and swollen joint count, patient assessment of pain and global score of ... observers (DH and AASSK) to evaluate the percentage of cell staining as the results of immunohistochemistry and TUNEL staining, using a score of to 4, as described previously [35] A score of indicated...
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Báo cáo y học: "Heterogeneity of autoantibodies in 100 patients with autoimmune myositis: insights into clinical features and outcomes" ppt
... associations of autoantibodies and extremely marked serologic heterogeneity Our data expand on previous studies of autoantibodies in AIM sera and show that the diversity of autoantibodies in AIM sera ... by clinicians and the diagnostic value of MSA and MAA tests [14] In the present report, we examine the same cohort for an expanded panel of 21 autoantibodies to major AIM autoantigens, using recently ... anti-fibrillarin by ALBIA using purified recombinant fibrillarin protein (Mikrogen GmbH, Neuried, Germany) and test serum diluted to 1:1,000 [36] Control negative and standard positive sera were included in...
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Cyclic nucleotides and mitogen-activated protein kinases: regulation of simvastatin in platelet activation pptx
... Triflavin inhibits platelet aggregation through direct interference with fibrinogen binding to the αIIbβ3 integrin [10] There is now a multitude of evidence suggesting that the binding of fibrinogen ... prostaglandin E1 (PGE1) (0.5 μM) and heparin (6.4 IU/ml) The washed platelets were finally suspended in Tyrode's solution containing bovine serum albumin (BSA) (3.5 mg/ml) The final concentration of ... Simvastatin (30 and 50 μM) did not significantly affect FITC-triflavin binding to the αIIbβ3 integrin in platelet suspensions (c, 4.8 ± 0.1; d, 4.9 ± 0.1) (Fig 1C), indicating that the inhibitory...
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báo cáo khoa học: " Molecular, genetic and transcriptional evidence for a role of VvAGL11 in stenospermocarpic seedlessness in grapevine" pptx
... C-terminal motif in the APETALA3 gene lineage BMC Evol Biol 2006, 6:30 64 Yang Y, Jack T: Defining subdomains of the K domain important for protein-protein interactions of plant MADS proteins Plant ... is of great interest Moreover, genetic mapping of intragenic VvAGL11 markers, in addition to revealing a putative functional role of the regulatory of the coding region of VvAGL11, resulted in ... analysis of the results and discussions and in the editing of the manuscript PH participated in the initial design of the project, discussions and editing the manuscript All authors have read and...
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Báo cáo y học: " Psychiatric diagnoses and punishment for misconduct: the effects of PTSD in combatdeployed Marines" pot
... deployment, psychiatric problems including PTSD, and Page of misconduct outcomes The objectives of this study were to ascertain and compare incidence rates of three types of misconduct outcomes (demotions, ... severe instances of blatant criminal conduct In order to classify individuals into the appropriate deployment cohort, all outcomes included in the analyses had to have occurred after a deployment Information ... [10,14,36,38,39], both of which could explain the increased behavioral problems in the war-deployed cohort The finding of greatest concern in this study is that combat deployed Marines with a PTSD...
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báo cáo khoa học:" Identification of clinically significant psychological distress and psychiatric morbidity by examining quality of life in subjects with occupational asthma" pot
... acknowledge in clinical practice when assessing a patient with asthma In our sample of individuals with OA who have been removed from exposure to the sensitizing agent, using a cut-off point of 5.1 in ... levels of psychological distress according to the anxiety and depression subscales of the PSI The highest Youden index of 0.53 was obtained when choosing less than 5.1 points as the cut-off for ... maintaining employment, increasing short term adherence to medication and improving the individuals quality of life while being costeffective [32] It a recent systematic review, Lerner and Henke...
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Báo cáo y học: " G-CSF and IL-8 for early diagnosis of sepsis in neonates and critically ill children – safety and cost effectiveness of a new laboratory prediction model: study protocol of a randomized controlled trial [ISRCTN91123847]" pps
... including differential and plasma levels of C-reactive protein Routine surveillance for ventilator-associated pneumonia comprises microbiological examination of the tracheal aspirate, including ... error under 5% and a power of 80% is 2300 The expected follow up rate is in excess of 90% Because the unit of randomization is days and not individuals, an unknown intracluster (intraday) correlation ... (R&D Systems, Abington, UK) marked after incubation and coupling with a second phycoerythrin monoclonal antibody (sandwich technique) (R&D Systems, Abington, UK) Final measurement and analysis is...
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Báo cáo y học: "Dietary weight loss and exercise interventions effects on quality of life in overweight/obese postmenopausal women: a randomized controlled trial" doc
... of this study was to examine the individual and combined effects of dietary weight loss and exercise interventions on HRQOL Defining the individual and combined effects of diet and exercise interventions ... gradually increased the intensity and duration of exercise training to 70-85% of maximal heart rate (using Polar heart rate monitors, Lake Success, NY) for 45 minutes per session and maintained this ... changes in HRQOL during the intervention The findings would provide information to explain potential mechanisms of how diet and exercise interventions affect HRQOL Methods The Nutrition and Exercise...
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![thang nguyen ngoc - 2011 - corporate governance and its impact on the performance of firms in emerging countries - the evidence from vietnam [cg]](https://media.store123doc.com/images/document/2015_01/02/small_rfd1420194809.jpg)
thang nguyen ngoc - 2011 - corporate governance and its impact on the performance of firms in emerging countries - the evidence from vietnam [cg]
... N.N. Thang / VNU Journal of Science, Economics and Business 27, No. 5E (2011) 12‐19 of the stock market and a transparent economy in Vietnam In the light of the both domestic and international attention ... which often includes employee representatives In contrast, in the US and UK, companies have adopted a single board of directors system, which has the primary role of protecting the shareholders' interests ... investors and help improve the good conditions of financial markets In addition, good corporate governance practices result in efficiency and productivity gains for individual companies and their investors,...
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![thang nguyen ngoc - 2011 - corporate governance and its impact on the performance of firms in emerging countries - the evidence from vietnam [cg]](https://media.store123doc.com/images/document/2015_01/06/small_tlw1420548434.jpg)
thang nguyen ngoc - 2011 - corporate governance and its impact on the performance of firms in emerging countries - the evidence from vietnam [cg]
... N.N. Thang / VNU Journal of Science, Economics and Business 27, No. 5E (2011) 12‐19 of the stock market and a transparent economy in Vietnam In the light of the both domestic and international attention ... which often includes employee representatives In contrast, in the US and UK, companies have adopted a single board of directors system, which has the primary role of protecting the shareholders' interests ... investors and help improve the good conditions of financial markets In addition, good corporate governance practices result in efficiency and productivity gains for individual companies and their investors,...
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Corporate governance and its impact on the performance of firms in emerging countries The evidence from Vietnam
... examining and monitoring the actions of senior management In addition, there are also other stakeholders that can influence a company, including employees and unions, suppliers, clients, and ... shares in board which companies that are often includes perceived as conforming to employee higher corporate representatives governance standards In In contrast, in the US and UK, contrast, investors ... Thang / VNU Journal of Science, Economics and Business 27, No 5E (2011) 12-19 of the stock market and a transparent economy in Vietnam In the light of the both domestic and international attention...
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Báo cáo khoa học: Reductive nitrosylation and peroxynitrite-mediated oxidation of heme–hemopexin doc
... giving a stable bis-histidyl complex (Fig 1) Heme binding and release results from the opening and closing of the heme-binding pocket, via movement of the two b-propeller domains and ⁄ or the interdomain ... Pseudo-enzymatic properties of heme–hemopexin Fig Kinetics of peroxynitrite -mediated oxidation of HPX–heme(II)–NO in the absence and presence of CO2, at pH 7.0 and 10.0 °C (A) Steady-state and kinetic difference ... role in functioning nodules? J Biol Inorg Chem 10, 935–945 Herold S, Exner M & Boccini F (2003) The mechanism of the peroxynitrite -mediated oxidation of myoglobin in the absence and presence of...
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Tài liệu Báo cáo khoa học: Critical roles of Asp40 at the haem proximal side of haem-regulated phosphodiesterase from Escherichia coli in redox potential, auto-oxidation and catalytic control doc
... dotted and cyan broken lines, respectively The figure was obtained using PYMOL [20] characteristics, including optical absorption spectra, cyanide binding, redox potential and auto -oxidation rates of ... ligand binding access channel at the haem distal side and/ or structure in terms of cyanide binding in the Fe(III) complex Redox potentials Fig Soret and visible optical absorption spectra of ... Cyanide binding rates, redox potentials and auto -oxidation rates of the Asp40Ala and Asp40Asn mutants of Ec DOS PAS Cyanide binding rate, experimental errors are within 20%; kox, autoxidation...
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Báo cáo khoa học: Degradation of chitosans with chitinase B from Serratia marcescens Production of chito-oligosaccharides and insight into enzyme processivity docx
... a DP of 3.04 and a FA of 0.44, and was concluded to consist mainly of DDA and DAA, in addition to minor amounts of ADA The tetramer fraction showed a DP of 4.1 and a FA of 0.33 and the dominant ... be even-numbered regardless of the initial binding mode, leading to the observed initial dominance of even-numbered oligomers Interestingly, the initial formation of even-numbered oligomers all ... Degradation of chitosans with ChiB Taking together all information and observations, ChiB is likely to initially bind the chitosan chain with similar chances of having an odd or even number of...
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Water pollution and habitat degradation in the Gulf of Thailand ppt
... Heavy metals in seawater and sediments of the eastern coast of the Inner Gulf of Thailand In: Proceedings the 5th Seminar on Research in Water Quality and Quality of Living Resources in Thai Waters, ... especially in the inner Gulf of Thailand It is evident that the increasingly deteriorating conditions in the marine environment of the inner Gulf of Thailand have threatened the existence of several ... 1984 Total mercury in bivalves of the east coast of the inner Gulf of Thailand In: Proceedings the 3rd Seminar on Research in Water Quality and Quality of Living Resources in Thai Waters, 26–28...
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