... disease Because HXA3 may play an important step underlying the pathophysiology of in ammatory diseases, such asin ammatory bowel disease, the investigation of human 12- LOX genes at mucosal surfaces, ... protein, SipA, promotes a lipid signal transduction cascade that recruits an ADP-ribosylation factor guanine nucleotide exchange factor (such as ARNO) to the apical plasma membrane ARNO facilitates ... Protein kinase Calpha-dependent increase in Ca2+-independent phospholipase A2 in membranes and arachidonic acid liberation in zymosan-stimulated macrophage-like P388D1 cells Biochem Pharmacol 63,...
... or as later invasive stage [46–48] Thus, in most cases, choriocarcinoma has the appearance of trophoblast, being predominantly syncytiotrophoblastic or cytotrophoblastic Some cytotrophoblastic ... island and cell columns, is formed which maintains the ability of proliferation and invasion Choriocarcinoma is a malignant neoplasm that represents the early trophoblast of the attachment phase ... cell association and degradation of 125 I-labeled Table Specific binding of 125 I-labeled HDL to choriocarcinoma cell lines at °C Binding constants were calculated by non linear regression analysis...
... Dewpura et al endogenous inhibitor, a catalytic domain characteristic of serine proteases and a C-terminal Cys- and His-rich domain implicated in enzyme stability and protein– protein interaction ... the prodomain, the common naturally occurring A5 3V variation that has no significant effect on plasma cholesterol levels and the R46L variation, a naturally occurring variant associated with hypocholesterolemia ... shots and masses were externally calibrated with All -in- 1 Protein Standards (Ciphergen Biosystems Inc.) All data were normalized for total ion current and peak areas calculated using the indirect...
... carrying out a conversation and had been residing in the NHs for at least months We defined mentally intact as having a Clinical Dementia Rating (CDR) ≤ 0.5 [22], which was assessed by trained nurses ... occupational therapy and participation in the political, cultural and religious arenas In this way, health care professionals can encourage the residents to engage in activities in the NH and in activities ... covariates (age, sex, martial status, educational level), the variable length of stay was not statistically significant for any subscale Adjusted R2 was unchanged for mental health and vitality...
... with a mass in her left breast 21 years after being diagnosed with invasive ductal carcinoma of the right breast, treated by a right mastectomy and axillary dissection followed by radiotherapy and ... Based on imaging, the diagnosis was a probable angiosarcoma Due to the presence of a pacemaker for cardiac arrhythmia and full anticoagulation therapy for a pulmonary embolism, magnetic resonance ... hypertension, a pacemaker for cardiac arrhythmia and was also treated with acenocoumarol for a pulmonary embolism two years ago Magnetic resonance imaging (MRI) was not feasible due to the pacemaker We...
... Sasaki H, Takada E, Sunagawa M, Masawa N: Fine needle aspiration of toxoplasmic lymphadenitis in an intramammary lymph node A case report Acta Cytol 2001, 45:259-262 Siriwardana et al Journal ... [2] Page of Conclusions Toxoplasmosis rarely presents asa mass in the axillary tail of the breast and may be considered asa differential diagnosis in patients presenting with axillary lymphadenopathy ... presenting asa swelling in the axillary tail of the breast and a palpable axillary lymph node mimicking malignancy: a case report Journal of Medical Case Reports 2011 5:348 Submit your next manuscript...
... Golden A, Brashear J, Robinson J, Rapp M, Klass M, Ostrow DH, Mandecki W: Recombinant mouse-human chimeric antibodies as calibrators in immunoassays that measure antibodies to Toxoplasma gondii ... results in the medical laboratory Eur J Clin Chem Clin Biochem 1996, 34:983-999 13 Koshy A, Grover S, Hyams KC, Shabrawy MA, Pacsa A, al-Nakib B, Zaidi SA, al-Anezi AA, al-Mufti S, Burans J, Carl ... was evaluated by SDS-PAGE analysis The bands that showed the maximum staining were observed at 50 kDa and 25 kDa, and these bands corresponded to the molecular weights of heavy and light chains...
... interpretation, and drafted the manuscript LE was the lead for statistical analysis RT was involved in study design and data interpretation SR was involved in study design and data interpretation All authors ... Allmiral LE and RT are employees of GSK SR has consulted or participated in advisory boards for: Able Associates, Adelphia Research, Almirall/Prescott, APT Pharma/Britnall, Aradigm, AstraZeneca, ... Sputum samples were obtained at the start of the study (baseline) and after year Sputum induction was performed using 3% saline given as nebulisations each lasting for minutes Selected sputum was...
... string of such co-ordinates A polygon is a closed line The grid-based format of data is captured as information of each quadratic cell ina screen and could be looked at asa photo of the area ... provide maps which show the spread of the disease by displaying the maps asa movie The GIS can also be incorporated ina real time outbreak notification, as done in an eradication program of the Aujeszky’s ... the case farm and all farms at risk within a specified area of the outbreak Buffer zones can be drawn around those farms as shown in Fig and with a link to tables of the addresses of the farms at...
... protocol planning, was a primary data gatherer and drafted the manuscript SC participated in data collection and statistical analysis VN performed statistical analysis LB participated in data collection ... was used to identify independent variables associated with death Variables that were associated with mortality in univariate analysis were considered for inclusion in the model, whereas parameters ... ventilation, length of stay, and the number of failing organs Statistical analysis Continuous variables' data are expressed as mean value ± SD Bi-variate hypotheses involving continuous variables...
... Therefore, a The parameter À determines how easily mobility itself can change The increase in this parameter accelerates the growth of the mean character value as well as the standard deviation The increase ... be hindered by an increase in mutational genetic load Indeed, the mean rates of spontaneous mutation with a qualitative effect in various plants and animals per locus and per generation are quite ... the character value also grow, ie the level of interspecies variation in the character value increases of species with the final stationary distribution retains a large share low character value...
... classes: Class I AP Endonucleases Class I AP endonucleases are also known as AP Lyases (or β-lyases) as they process the AP sites by the β-elimination reaction, which involves the removal of a ... agents including chemotherapeutic agents Removal of the damaged base by a DNA glycosylase creates an apurinic / apyrimidinic (AP) site AP endonuclease1 (Ape1), a critical component in this pathway, ... radiation therapy are the mainstream treatment options available to treat cancers Many chemotherapeutic drugs act by damaging DNA, which leads to an accumulation of damage resulting in impaired...
... describing, classifying and defining and the four different kinds of explanation including: sequential explanation, causal explanation, factorial explanation, and theoretical explanation have been ... especially in the US as genre has in recent years become associated with a disreputably formulaic way of constructing particular texts - a kind of writing or speaking by numbers This association, as ... certain starting point That is to say she/he needs to rely on a language asa base then compare the other language from certain parameters established In this case, the two languages involved are English...
... describing, classifying and defining and the four different kinds of explanation including: sequential explanation, causal explanation, factorial explanation, and theoretical explanation have been ... especially in the US as genre has in recent years become associated with a disreputably formulaic way of constructing particular texts - a kind of writing or speaking by numbers This association, as ... certain starting point That is to say she/he needs to rely on a language asa base then compare the other language from certain parameters established In this case, the two languages involved are English...
... Personal importance is also considered as central in other research areas For instance, according to the self-evaluation maintenance model, individuals try to achieve a task or goal to maintain ... research on appraisal theories has shown that the appraisal of agencyothers is associated with anger and the appraisal of agency-circumstances is associated with sadness Research has also revealed ... personal importance can be construed as an individual difference variable or asa manipulated state Appraisal theorists have argued that personal importance is a primary motivation, stating that there...
... applications have been used in total synthesis context A potent nonalkaloid psychoactive substance and naturally occurring hallucinogen diterpene, ‘salvinorin A was prepared ina transannular ... transannular radical cyclizations to form natural products, typically via radical reaction cascades 11 Scheme 10 Cascade radical-mediated cyclization of the iododienynone 1.50 ina transannular ... join his research group He was always patient and encouraging independent thinking with valuable guidance at critical points I would like to thank my husband Ravi Kumar Sriramula for his valuable...
... (Mw = 200,000) was purchased from Hayashibara (Tokyo, Japan) Epirubicin·HCl (EPI·HCl) was purchased from Hisun Pharmaceutical Co (Zhejiang, China) Poly (vinyl alcohol) (PVA) with an average molecular weight ... and the acute toxicity of PANs was evaluated in mice Morever, EPI was loaded into PANs and its pharmacokinetics was also assessed in rats to compare to the free drug Methods Materials Pullulan ... Wistar rats The plasma levels over 48 h are shown in Figure and the PK parameters are summarized in Table The peak concentration of total EPI in plasma was 14.65 mg/L at 1 min after injection and...
... the individual difference variables alters For example, ina formal setting intelligence and aptitude play a dominant role in learning, while exerting a weaker influence in an informal setting ... university graduation, applying for a job, requesting higher pay based on language ability, reading technical material, translation work or achieving higher social status Instrumental motivation is ... of the amount of time spent studying the language and then output, expressed as linguistic performance when investigating language learning In order to examine language learning in the Japanese...