reduction of neuronal apoptosis by small molecules promise for new approaches to neurological therapy
Systemic risks of genetically modified crops the need for new approaches to risk assessment
... justifiable to apply methods developed for toxicology assessment of chemical substances to viable and reproducible organisms or if new methods had to be developed The differences between the testing approaches ... potential for controversy This is often best done by involving the spectrum of participants in every step of the decision-making process, starting with the very formulation of the problem to be analysed ... of genetically modified crops Edited by: Halford N New York: John Wiley 2006:225-239 Stein AJ, Rodríguez-Cerezo E: The global pipeline of new GM crops: implications of asynchronous approval for...
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Báo cáo khoa học: Reduction of S-nitrosoglutathione by human alcohol dehydrogenase 3 is an irreversible reaction as analysed by electrospray mass spectrometry pptx
... addition to the ADH3 substrate repertoire and here we investigate the enzymatic activity of the human form of ADH3 for this compound Recombinant expression and purification of wild-type and mutated forms ... adduct formation Determination of kinetic constants for NADH and NADPH were performed with a GSNO concentration of 0.5 mM Determination of kinetic constants for NAD+ and NADP+, were performed ... buffer as compared to that used for kinetic analyses Enzyme purification and chemicals Generation of expression vectors for recombinant expression of the wild-type and mutant forms of ADH3 have previously...
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báo cáo hóa học:" Reduction of graphene oxide by an in-situ photoelectrochemical method in a dye-sensitized solar cell assembly" ppt
... is due to the reduction of the GO film by the photoinduced electrons With the reduction proceeding, the increase of FF and η slows down and approaches to a limitation at last After the photoelectrochemical ... the bandgap of RGO increases with the oxidation level Controlling the ratio of sp2 carbon atoms to sp3 carbon atoms by reduction chemistry is a powerful way to tune its bandgap Therefore, RGO can ... removed by centrifugation at 3,000 rpm for Fabrication of DSSCs To realize the in-situ photoelectrochemical reduction, GO counter electrode was used for DSSCs The GO electrode was prepared by drop...
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Báo cáo khoa học: "Reduction of radiation pneumonitis by V20-constraints in breast cancer" pps
... opacification were added together to form total scores ranging from to Total scores of 1-3 were considered to represent slight radiological RP and score of 4-9 moderate to severe RP This method has ... the termination of RT The patients were classified into three groups according to CTC-criteria (version 2.0) [19] No complications: no registered respiratory symptoms monitored by the clinician ... defined Monitoring for symptomatic pneumonitis and evaluation of radiological pneumonitis on X-ray and CT with the Arrigada’s classification All patients were followed for respiratory symptoms, i.e...
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Báo cáo y học: "System in biology leading to cell pathology: stable proteinprotein interactions after covalent modifications by small molecules or in transgenic cells" pot
... use of small molecules also leads to cancer [1] This understanding of apoptosis in disease development did not give a solution for the treatment of degenerative diseases and led to very toxic ... MalinaLab-Axanton, Tiefenaustr.110, CH-3004 Bern, Switzerland cancer and too much apoptosis leads to degenerative diseases Consequently, cancers are treated with small molecules to induce apoptosis; ... regulatory sequences and leads to erroneous signaling resulting in cell pathology We observed that the covalent modification of the proteins by small molecules is the mechanism of formation of a new...
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Design and synthesis of donor acceptor hybridized small molecules and graphene derivatives for photovoltaic and optical studies
... ratio of the number of charge carriers collected by the solar cell to the number of photons of a given energy shining on the solar cell IPCE therefore relates to the response of a solar cell to ... enables to harvest a large amount of light with small amount of materials In addition, flexibility of organic molecules with ease of processing makes it potentially lucrative for photovoltaic ... quantity used to measure cell performance It is a measure of the squareness of the J–V curve The formula for FF in terms of the above quantities is FF = J mpp × Vmpp J sc × Voc Incident photon to electron...
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Structural basis for recruitment of traffic proteins by small GTPases
... neck of each bud to regulate the rate of the bud pinching-off to form a vesicle With the help of these proteins around the neck, the two noncytosolic leaflets of the membrane are brought close to ... dissociation of GEF from small GTPases and activating the small GTPases to allow the interaction with downstream effectors There are many varieties of GEFs of small GTPases Small GTPases are recognized by ... biochemical studies of small GTPases showed that there are two interconvertible forms of small GTPases: a GDP-bound inactive form and a GTPbound active form In the GDP-bound form, small GTPases can...
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Tài liệu Báo cáo Y học: Structural and biochemical characterization of neuronal calretinin domain I– II (residues 1– 100) Comparison to homologous calbindin D28k domain I–II (residues 1 –93) pdf
... activator of photoreceptor guanylyl cyclase by preventing a Ca21-induced ‘activator-toinhibitor’ transition J Biol Chem 271, 19346– 19350 Craescu, C.T., Precheur, B., van Riel, A., Sakamoto, H., ... 4749) The AUTOASSIGN program [37] was used to obtain automatic assignments By running the program with several sets of parameters, we were able to obtain a consistent auto-assignment for residues ... is difficult to localize the biochemical properties of CR and Calb to particular domains but this information can be obtained by studying protein fragments For example, the structure of the calcium-bound...
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evaluation and comparison of management strategies by data envelopment analysis with an application to mutual funds
... Evaluation of Performance of Mutual Fund Strategies by Comparison of Efficient Frontiers—Joint Exemplar DEA 173 Section 3.4 Step Four: Performance of Mutual Fund Strategies by Comparison of Efficient ... Requirements for the Degree of Doctor of Philosophy The University of Texas at Austin May 2006 UMI Number: 3245797 UMI Microform 3245797 Copyright 2007 by ProQuest Information and Learning Company ... Application to Mutual Funds by Chester Lewis Wilson, B A Dissertation Presented to the Faculty of the Graduate School of the University of Texas at Austin in Partial Fulfillment of the Requirements for...
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Báo cáo hóa học: " Detection of epithelial apoptosis in pelvic ileal pouches for ulcerative colitis and familial adenomatous polyposis" pot
... factors for disease of ileal pouch-anal anastomosis after restorative proctocolectomy for ulcerative colitis Clin Gastroenterol Hepatol 2006, 4(1):81-89 Armstrong DN, Sillin LF, Chung R: Reduction ... be due to the fact that both inflammatory and apoptosis pathways are related Furthermore, the major pathway of apoptosis in these cases were intrinsic mitochondrial pathway characterized by APAF-1 ... immunoblotting, immunoprecipitation assays and histological analysis to determine the expression of pro-apoptotic and anti-apoptotic proteins, and detection of apoptosis by Annexin V fluorescence microscopy...
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Báo cáo sinh học: " Regulation of FeLV-945 by c-Myb binding and CBP recruitment to the LTR" doc
... regulator of their differentiation along multiple hematopoietic lineages [13] The results demonstrated a significant reduction in complex formation in the presence of the cMyb site competitor, ... complex formation in the presence of nuclear extract (lane 2), and complex formation in the presence of 200-fold molar excess of non-specific (lane 3) or specific competitor (lane 4) Reaction performed ... of the 21-bp element was required for complex formation (Figure 3C) The c-Myb transcription factor is a critical regulator of gene expression, proliferation and differentiation in early hematopoietic...
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báo cáo hóa học:" Regulation of FeLV-945 by c-Myb binding and CBP recruitment to the LTR" doc
... regulator of their differentiation along multiple hematopoietic lineages [13] The results demonstrated a significant reduction in complex formation in the presence of the cMyb site competitor, ... complex formation in the presence of nuclear extract (lane 2), and complex formation in the presence of 200-fold molar excess of non-specific (lane 3) or specific competitor (lane 4) Reaction performed ... of the 21-bp element was required for complex formation (Figure 3C) The c-Myb transcription factor is a critical regulator of gene expression, proliferation and differentiation in early hematopoietic...
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NEW APPROACHES TO CHARACTERIZATION AND RECOGNITION OF FACES by Peter M. Corcoran doc
... Segmental K-means: according to the new segmentation performed at step 4, another K-means is applied to the current set of observation vectors corresponding to each new state, and new observation probability ... recognition process: size of face image, topology of the model, that is number of superstates, number of states for each super state and number of Gaussians to model the observation vectors, illumination ... prototype EHMM: parameters: N ik the numbers of states, N the number of superstates , K the number of Gaussians used to model the probability density for the observation vectors in each state of...
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Tài liệu The New Face oF GoverNmeNT: How Public Managers Are Forging a New Approach to Governance pdf
... included positions as director of economic development for the City of Fullerton, California, and communications director for the majority caucus of the Washington State House of Representatives, David ... highly creative approaches to solving old problems while forging new solutions to new problems Of course, there are a number of reasons why some of these innovations and transformational changes ... guided public administrators for more than a century has been turned on its head, to be replaced by a new type of governing by new kinds of public managers (Rhodes 1997) Actions to change the way government...
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Understanding Tuberculosis – New Approaches to Fighting Against Drug Resistance Edited by Pere-Joan Cardona potx
... control of tuberculosis There is need for health workers to be able to quickly detect resistant forms of tuberculosis and also to be able to distinguish clearly between active and latent forms.Efforts ... Restlessness Same to Ciprofloxacin 500 mg/day MIC 0.50 to 0.75 g/mL (Rastogi et al., 1996) Same as for Ciprofloxacin Same to Levofloxacin 600 - 800 mg/day Same as for MIC 0.12-2 Ciprofloxacin g/mL ... – New Approaches to Fighting Against Drug Resistance 2.1.4.2 Mode of action It blocks formation of Mtb cell wall by interfering in the synthesis of arabinogalactan (an essential component for...
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Third-Party Provision of Ancillary Services; Accounting and Financial Reporting for New Electric Storage Technologies doc
... ability of a seller to perform a market power study for ancillary services that were present at the time of Avista appear to remain today for sellers in some regions of the country As such: a Is information ... difficult for regulators to determine costs and establish appropriate rates for new energy storage technologies Therefore, the Commission is seeking comments on accounting for the costs of energy storage ... how to revise them to include information on energy storage plant and operations a Should the Form Nos and 1-F be amended to provide the detailed information required to monitor energy storage...
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motley - darwin's harvest - new approaches to the origins, evolution and conservation of crops (columbia, 2006)
... both tomatoes and potatoes are of New World origin (figure 1.1) At the time of their introduction into the Old World, Europeans did not immediately accept these crops because they were similar to ... identification of markers linked to a Pseudomonas resistance gene in tomato by using random primers and near-isogenic lines Proceedings of the National Academy of Sciences, USA 88: 2336–2340 McClintock, ... goal of this book is to provide a broad sample of current research on a diverse group of crop plants The chapters use many methods and molecular markers to shed further light on the topics of plant...
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Báo cáo hóa học: " Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies" pot
... cells to apoptosis in case of DNA repair failure [57] Despite this, CM cells are extremely resistant to undergoing apoptosis following conventional cytotoxic therapies In light of the information ... immunomodulatory activity, being able to concomitantly up-regulate molecules that are essential for the presentation of immunogenic peptides to immune cells, and for the recognition and cytotoxicity of ... the modulation of accessibility of DNA for the transcriptional machinery The acetylation status of histones is controlled by the balanced action of histone acetyltransferases and histone deacetylases,...
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báo cáo hóa học:" Impact of HIV-1 viral subtype on disease progression and response to antiretroviral therapy" pot
... every three to six months The criteria for initiation of ART are the presence of a CD4 cell count of < 350 cells/mm or the presence of symptomatic HIV disease CD4 cell counts were Page of determined ... adherence was calculated for each patient visit by dividing the total number of missed or late doses by the total number of doses prescribed over a 30-day period, multiplied by 100 Percent adherence ... analysis was used to examine for independent predictors of rate of CD4 decline using a backward elimination procedure As the date of infection was not known in the majority of cases, all multivariate...
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NEW APPROACHES TO CHARACTERIZATION AND RECOGNITION OF FACES pptx
... Segmental K-means: according to the new segmentation performed at step 4, another K-means is applied to the current set of observation vectors corresponding to each new state, and new observation probability ... recognition process: size of face image, topology of the model, that is number of superstates, number of states for each super state and number of Gaussians to model the observation vectors, illumination ... prototype EHMM: parameters: N ik the numbers of states, N the number of superstates , K the number of Gaussians used to model the probability density for the observation vectors in each state of...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25