rationale behind the preparation of solid dispersion
Knowledge discovery in biomedical research and drug design the development and application of biological databases
... remaining drugs will be excreted out of the body with the help of some proteins The deposit of drugs or their metabolites is one of the causes of the cytotoxicity Therefore, a successful drug candidate ... cure of patient, and they are also the causes of many instances of morbidity Therefore, the understanding of the possible mechanisms of ADRs would be helpful for the successful treatment of patients ... one must determine the content and objective of the database, which are the reason and the essence of the existing of database Therefore, before starting the construction of the database, several...
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Báo cáo khoa học nông nghiệp " Evaluation of the Sawmiller Training Course Assessment " potx
... where the people live g) The standard model with relationship with Vietnamese people h) Visit the sawmill to learn about the mills they use i) Overall the concept is not suitable j) Join the sawmills ... Nothing f) Furniture design requirements g) The course needs to match the conditions of the company h) – No comments Question What was the best part of the course? a) All good b) Sawing c) - Work ... suitable for the workforce c) Would like more photos in teaching, with relation to the International Standards, More practice rather than theory, d) The training was suitable for business e) they have...
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Evaluation of customer satisfaction using vinaphone
... "Quality of service is the level difference between the expectations of the consumers of services and their perceptions of the outcome of the service " Understanding quality of service is the basis ... 3.1.1 The percentage of calls are successfully established: the ratio of the number of calls is set on the total number of successful calls ( 92%) 3.1.2 The rate of dropped calls: is the ratio ... follows: "Quality of service is the result of the aggregate indicators of the level of user satisfaction with the service for that service." 10 Under this standard, the quality of service targets...
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Stability and in vivo evaluation of pullulan acetate as a drug nanocarrier
... Eindhoven, Holland) The stability of PANs in water In order to study the stability of PANs, the above dispersions were stored for months at 4°C Macroscopic characteristics of NPs dispersions such ... major contributor for the clearance of NPs, thus the reducing rate of MPS uptake could be considered as the best strategy for prolonging the circulation of NPs (Li & Huang, 2008) Therefore, PA/EPI ... respectively The bioavailability of free EPI was 100%, the BAR of PA/EPI calculated through the equation above by the AUC0–24h was 189%, much higher than the free drug According to the previous...
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Evaluation of heat pumps usage and energy savings in residential buildings
... most of the control variables came out with the same expected signs, where average monthly consumption increases with the increase in the # of occupants , the number of stories in the house The ... adjusted to 7 0oF during the heating months The house originally has an electrical furnace and retrofitted to heat pump The figure shows the same trend for the two methods of heating The energy consumption ... where N is the number of homes in the overall sample, and LN HSIZE is the natural log of the House Size variable The variable of interest in this model is heat pump (HPUMP) This is the independent...
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Evaluation of employees’ job satisfaction and role of gender difference an empirical study at airline industry in iran
... by their needs These theories focus on employees‟ diverse needs and the cognitive process behind these diversities In these theories, sources, and causes of employees‟ behaviors, as well as the ... characteristics of the job (Wexley and Yukl, 1984) To get deep understanding of employees, characteristics of jobs and their relation to the issue of job satisfaction various theories have been formulated These ... in the literature These frameworks are named as content theories and process theories In the following sections the main theories and theorists from each framework are discussed to clarify the...
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Evaluation of the Patient Safety Improvement Corps pot
... tools incorporated in the PSIC program The goal of the train -the- trainer portion of the PSIC is to broaden the reach of the PSIC to more individuals and organizations throughout the United States ... Content of the PSIC Training Both groups of trainees interviewed felt that the content of the training was targeted at the appropriate level Of the skills and tools taught during the course, the ... indepth appreciation of the complexities of patient safety coming out of the program, but they underscored a need for continued training beyond the end of the third week of training The Year trainees...
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Safety Evaluation Of Certain Food Additives potx
... used in solid food and 50% in beverages and that only 25% of the total amount of solid food and beverages in the food supply contain the food additive, the theoretical maximum level of cyclamates ... the presentation of the material in this publication not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, ... However, the sequence alignment of the two enzymes showed that there are large differences in the loop regions, and the overall identity is only about 32% As the two enzymes belong to the same...
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drug safety evaluation
... 1983) The fall of 1937 witnessed the beginning of the often-told Elixir of Sulfanilamide incident, which remains one of the nation’s worst drug tragedies The Massengil Company was not one of the ... Statistical modeling of the assay system may lead to the improvement of the design of the system by reducing the interval between discoveries of active compounds The objectives behind a screen and ... exposure of animals to the last observation and termination of the animals) is called the in-life phase, and many people assume the length of the in-life phase defines the length of a study Rather,...
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Báo cáo hóa học: "Safety evaluation of allogeneic umbilical cord blood mononuclear cell therapy for degenerative conditions" pot
... patients had other diagnoses (Table 1) The local institutional review board of the Nanshan Affiliated Hospital of Guangdong Medical College, under the auspices of the National Ministry of Table Patients ... applications The reason for this is has been the argument that the potential adverse effects of myeloablative therapy outweigh possible regenerative activities The current study investigated the safety of ... [20] These incidence rates are also similar to those of the published PBPC and Ficoll groups (grouped by isolation method) Of the full range of laboratory parameters in the analysis, only the...
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báo cáo hóa học: " Safety evaluation of topical applications of ethanol on the skin and inside the oral cavity" pdf
... [125,126] The possibility of damage to the oral mucosa also exists with the use of mouthwashes [127] An overview of the effect of ethanol on the oral mucosa is shown in Figure Local damage to the mucous ... facilitates that of the solute (in the sense of a simple co-permeation) [79,80] Side-effects of the transdermal patches were cutaneous reactions, where ethanol proved to be one of the causes of cutaneous ... of age) and one adult The legs of the subjects were wrapped in cotton from above the knees to the feet, and the wrappings were subsequently soaked with 200 ml of 95% (v/ v) ethanol Although the...
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báo cáo hóa học:" Psychometric evaluation of the Osteoporosis Patient Treatment Satisfaction Questionnaire (OPSAT-Q™), a novel measure to assess satisfaction with bisphosphonate treatment in postmenopausal women" potx
... clinical characteristics of the study population at baseline The analysis of the OPSAT-Q data focused on how well the items satisfied assumptions underlying The distributions of the individual OPSAT-Q ... The range for the CSS was 44 to 100 The percentage of subjects scoring at the floor was 1% for all subscales and composite scores Among the subscales, the percentages of subjects scoring at the ... should be underlined that the design of The composition of the subscales is supported by the fact that the OPSAT-Q items were more highly correlated with their hypothesized scales than competing...
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báo cáo hóa học: " Psychometric evaluation of the SF-36 (v.2) questionnaire in a probability sample of Brazilian households: results of the survey Pesquisa Dimensões Sociais das Desigualdades (PDSD), Brazil, 2008" docx
... validity On the other hand, the validity of the Mental Component of the Brazilian version of the SF-36 (v.2) was lower than reported in other studies in view of the lower factor loadings of the Social ... calculated as the ratio of the largest F-value obtained among scales to the F-value of the scale Data from the heads of Page of 10 households and their spouses were weighted to represent the total ... in rural areas of the Northeast to 31% in the metropolitan region of Rio de Janeiro, and 23% in the richest tracts of metropolitan areas The estimated number of households in the sample accounted...
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Báo cáo hóa học: " Research Article Evaluation of Different Power Saving Techniques for MBMS Services" pptx
... services On the other hand, the performance of the available PtP channels for serving such services depends mainly on the number of the users that are served However, the utilization of these channels ... The determination will provide the RNC with the possibility of commanding the Node B to switch between these channels based only on the number of users, with main objective the reduction of the ... covered In the first case the region is the 50% of the cell (Figure 9), while in second the 95% of the cell (Figure 10) Each figure presents the power required for the transmission of an MBMS service...
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Báo cáo khoa học: "Radiosurgery for pituitary adenomas: evaluation of its efficacy and safety" ppsx
... medical therapy and patients inoperable or who refuse surgery The objectives of radiotherapy are the control of tumor growth and/or the normalization of hormonal secretion, the maintenance of pituitary ... confirms the adequacy of indications of the procedures and plans made More even than the concern about the pituitary function, we observe the maximum dose considered safe in the optic pathways and often ... more important than the prescribed dose, the appropriate definition of the target volume is critical to the success of tumor control For this, besides the careful evaluation of imaging studies,...
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Báo cáo khoa học: " Intraoperative radiotherapy (IORT) combined with external beam radiotherapy (EBRT) for soft-tissue sarcomas – a retrospective evaluation of the Homburg experience in the years 1995–2007" pdf
... responsible for the treatment of the majority of the patients and control of the documentation as well as review of the manuscript NL was responsible for the plans and control of the procedures ... CB was responsible for the evaluation of the patients' records, collection of the data, letters to the patients and the referring doctors, and the entry of the data to the databank system CR ... age at the beginning of treatment was 56 years, the mean Karnofsky performance status 92% In the majority of cases the sarcomas were located in the lower extremities or the retroperitoneum The most...
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báo cáo khoa học: "Ultrasound microbubble-mediated delivery of the siRNAs targeting MDR1 reduces drug resistance of yolk sac carcinoma L2 cells" doc
... level Page of 11 of MDR1 in L2-RYC cells The highest silencing efficiency was observed in the pooled plasmids group (Figure 1C) Therefore, for the following experiment, we chose to use the pooled ... data of Ct value for MDR1 in each group was normalized with GAPDH and measured as the fold change Preparation of the siMDR1-loaded lipid microbubble To prepare lipid microbubble, we mixed mg of ... The siMDR1-loaded lipid microbubble were obtained with an average diameter of 2.82 ± 0.76 μm, an average concentration of 8.74 × 109/ ml and the average potential of -4.76 ± 0.82 mV (n = 5) The...
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Báo cáo y học: " Mixed states vs. pure mania in the french sample of the EMBLEM study: results at baseline and 24 months – European mania in bipolar longitudinal evaluation of medication" ppsx
... (70%) of the patients considered they were satisfied with life (76% of the PM and 59% of the MS, p < 0.001) and only 9% of the patients were still dissatisfied (5% of the PM and 18% of the MS ... PM and 49% of the MS, p < 0.001) and 62% taking benzodiazepines (58% of the PM and 71% of the MS, p < 0.001) Treatment over 24 months Over the 24-month period, only a third (31%) of the population ... in the PM, 24% in the MS) Including the 31% of patients lost to followup over 24 months, 35% of the patients who had initiated a monotherapy at baseline maintained it over the period (45% for the...
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báo cáo khoa học: " Drug Checking: A prevention measure for a heterogeneous group with high consumption frequency and polydrug use - evaluation of zurich’s drug checking services" potx
... number of substances analyzed (2055) Of the subjects, 21.9% were women, and the average age was 27.8 years At the time of the survey, the youngest person was 15, and the oldest was 70 The majority ... to the collection and evaluation of the presented data, the city of Zurich today has a much greater knowledge of the substances used, the consumption patterns, and above all the drug users themselves ... opinion, the results of the evaluation of the questionnaire show that the users of party drugs form a quite heterogeneous group, which indicates the need for various measures For example, the lives of...
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báo cáo khoa học: " Designing an experimental HIV/HCV intervention to promote the safe re-use of drug preparation materials by injection drug users in Puerto Rico" potx
... community, and on the following day a session was held in the other community Thus the three rounds produced a total of six sessions At the beginning of each session, participants were offered refreshments; ... stream of water from the flip-top bottle (Figure 1a) into the syringe barrel, filling its entire length; replacing the plunger; expelling the water out the metal needle Advantages include: a) the ... syringes contacting drug preparation materials The overarching aim is to promote the safe re-use of drug preparation and injection equipment, and to impact the large number of IDUs in San Juan who...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25