randomized controlled clinical studies
Báo cáo y học: " A randomized, controlled clinical trial: The effect of mindfulness-based cognitive therapy on generalized anxiety disorder among Chinese community patients: protocol for a randomized trial" pdf
... A randomized, controlled clinical trial: The effect of mindfulness-based cognitive therapy on generalized anxiety disorder among Chinese community patients: protocol for a randomized ... disorder Methods A three armed randomized, controlled clinical trial including 9-month post-treatment follow-up is proposed Participants screened positive using the Structure Clinical Interview for DSM-IV ... of responding for individuals with generalized anxiety Although it has been shown in randomized controlled clinical trials that MBCT can reduce the likelihood of relapse in people with recurrent...
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báo cáo khoa học:"The WRITTEN-HEART study (expressive writing for heart healing): rationale and design of a randomized controlled clinical trial of expressive writing in coronary patients referred to residential cardiac rehabilitation" docx
... rehabilitation program The feasibility, safety and clinical efficacy of such a brief psychological intervention will be evaluated in a four-arm randomized controlled clinical trial with a Page of 12-month ... emotional expression in their social environments [36] Methods Study design A four-arm randomized controlled clinical trial with four follow-up assessments (immediately before discharge from hospital, ... WRITTEN-HEART study (expressive writing for heart healing): rationale and design of a randomized controlled clinical trial of expressive writing in coronary patients referred to residential cardiac...
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Báo cáo y học: "Effects of a fish oil containing lipid emulsion on plasma phospholipid fatty acids, inflammatory markers, and clinical outcomes in septic patients: a randomized, controlled clinical trial" docx
... emulsion on plasma phospholipid fatty acids, inflammatory markers, and clinical outcomes in septic patients: a randomized, controlled clinical trial Critical Care 2010, 14:R5 ... was not controlled Recently, Friesecke et al [24] reported that use of a mixed MCT/ LCT/fish oil lipid emulsion in critically ill ICU patients had no effect on inflammatory markers, or on clinical ... containing parenteral nutrition in septic ICU patients on markers of inflammation and on clinical endpoints However, studies of enteral nutrition providing fish oil, in addition to other potentially...
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Báo cáo y học: "omparative Efficacy and Tolerability of 5-Loxin® and Aflapin® Against Osteoarthritis of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study"
... of Boswellia extract [24-27], no human clinical studies were done to prove the efficacy and tolerability of Aflapin in osteoarthritis Hence in the present clinical study we sought to evaluate the ... 200 mg in the treatment of osteoarthritis in two identically designed, randomized, placebo -controlled, non-inferiority studies Rheumatology (Oxford).2007; 46: 496-507 Reginster JY, Malmstrom ... Aflapin was tested using a battery of safety studies conducted according to OECD guidelines and it was found to be safe [23] Although a significant number of clinical study reports support the anti-inflammatory...
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Báo cáo y học: " Effects of cyclophosphamide on pulmonary function in patients with scleroderma and interstitial lung disease: a systematic review and meta-analysis of randomized controlled trials and observational prospective cohort studies" ppt
... therapies, interstitial lung disease, randomized controlled trials, observational studies, multicenter studies, clinical trials phase II, clinical trials phase III, and clinical trials phase IV Diffuse ... assessment A total of 16 studies (three randomized double-blind controlled studies and 13 observational studies) were then examined in detail Five of the 13 observational studies were excluded due ... obtained from the observational studies and from the CYC experimental arm of the randomized clinical trials Additionally, we performed a meta-analysis of the randomized controlled trial results comparing...
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Báo cáo y học: "Several clinical interests regarding lung volume reduction surgery for severe emphysema: meta-analysis and systematic review of randomized controlled trials." docx
... Several clinical interests regarding lung volume reduction surgery for severe emphysema: meta-analysis and systematic review of randomized controlled trials Wei Huang, 1Wen ... We aim to address several clinical interests regarding lung volume reduction surgery (LVRS) for severe emphysema using meta-analysis and systematic review of randomized controlled trials (RCTs) ... reduction surgery and physical training on health status and physiologic outcomes: a randomized controlled clinical trial Chest 2005;128(5):3489-99 Sardenberg RA, Younes RN, Deheizelin D Lung...
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Báo cáo y học: "A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis" ppsx
... experiments in rodents have provided the basis for human clinical trials In a randomized, double-blind, multicenter, and controlled phase II clinical trial involving 236 patients with severe active ... participation in other clinical trials within months before enrolment Study design The study was a two-to-one, eight-center, 24-week follow-up, double-blind, double-dummy, randomized, and MTX -controlled ... [24] Clinical parameters also included body weight, blood pressure, and heart rate To standardize the evaluation of clinical variables, all investigators prior to study entry performed clinical...
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Báo cáo y học: "High frequency chest wall oscillation for asthma and chronic obstructive pulmonary disease exacerbations: a randomized sham-controlled clinical trial" pptx
... oscillation for asthma and chronic obstructive pulmonary disease exacerbations: a randomized sham -controlled clinical trial Respiratory Research 2011 12:120 Submit your next manuscript to BioMed ... assessed for eligibility Fifty-two (55%) were randomized to active HFCWO (n = 25) or sham HFCWO (n = 27) Discussion In this multi-center phase II clinical trial, we found that HFCWO initiated ... dyspnea over this treatment period Studies using a longer treatment period (e.g., through 30 days post-discharge) are needed to determine if HFCWO improves other clinically meaningful outcomes during...
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Báo cáo khoa học: "Stratification, Blinding and Placebo Effect in a Randomized, Double Blind Placebo-controlled Clinical Trial of Gold Bead Implantation in Dogs with Hip Dysplasia" doc
... under clinical procedure Dogs with previous acupuncture experience were also excluded from the study Study design The study was carried out as a randomised placebo -controlled and observer-blind clinical ... canine hip dysplasia (CHD) included in a double blind randomized clinical trial The numbers (n) indicate the number of dogs within each strata and randomized groups (G) = Gold implantation group (P) ... results of the clinical trial have been reported elsewhere (Jæger et al 2004) Gold bead implantation in dogs with hip dysplasia 61 Table Number of dogs participating in a clinical controlled therapy...
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Báo cáo y học: "Pro/con clinical debate: It is acceptable to stop large multicentre randomized controlled trials at interim analysis for futility" pptx
... algorithm for designing group sequential clinical trials Biometrics 2001, 57:972-974 Demets DL, Ware JH: Asymmetric group sequential boundaries for monitoring clinical trials Biometrika 1982, 69:661-663 ... Group Sequential Methods with Applications to Clinical Trials Boca Raton, FL: CRC Press; 2000:171–189 The National Heart, Lung, and Blood Institute ARDS Clinical Trials Network: Higher versus lower ... with the acute respiratory distress syndrome N Engl J Med 2004, 351:327-336 Anonymous: Randomized, placebo -controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory...
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Báo cáo y học: "Clinical review: Strict or loose glycemic control in critically ill patients - implementing best available evidence from randomized controlled trials" ppsx
... (closed bars) and strict glycemic control group (open bars) of seven randomized controlled trials Original single-center randomized controlled trials (RCTs) from Leuven [1,2]; single-center RCTs [3,4]; ... reduction (15.3% in the intervention group versus 17.2% in the control group) [7] Meta-analyses of randomized controlled trials of strict glycemic control Two meta-analyses, of which the first included ... Schultz et al Critical Care 2010, 14:223 http://ccforum.com/content/14/3/223 Page of Table Randomized controlled trials on strict glycemic control (target blood glucose levels of 80 to 110 mg/dl)...
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Báo cáo y học: "Effect of corticosteroids on the clinical course of community-acquired pneumonia: a randomized controlled trial" pot
... the International Standard Randomized Controlled Trials Register (ISRCTN22426306) Page of Interventions We aimed to analyze the effect of a steroid treatment on the clinical course and outcome ... article as: Fernández-Serrano et al.: Effect of corticosteroids on the clinical course of community-acquired pneumonia: a randomized controlled trial Critical Care 2011 15:R96 Submit your next manuscript ... as on the profile of the host inflammatory response For this propose we conducted a randomized, double blind, controlled trial Patients who were placed on systemic steroid therapy were compared...
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A double blind randomized placebo controlled clinical trial on the supplementation of probiotics in the first six months of life in asian infants at risk of allergic diseases effe
... against infections iv impact on growth and safety Methods: This double-blind, placebo -controlled randomized clinical trial involved 253 infants with a family history of allergic disease Infants ... initiation of this clinical trial, very few randomized trials had been reported to evaluate the efficacy of this strategy [8] This study was intended to substantiate or refute these earlier studies as ... rotavirus [86], Salmonella [87, 88], polio [89, 90] and cholera [91] in double-blind, randomized, controlled studies summarized in Table 1.2 Oral administration of L rhamnosus GG with live oral...
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Báo cáo y học: "Lifetime health effects and medical costs of integrated stroke services - a non-randomized controlled cluster-trial based life table approach"
... from different studies and settings (see Table 2), giving a population level estimates of the stroke burden This approach is similar to two recent UK studies [15,16] with all three studies arriving ... results of other studies ranged from a reduction of a relative risk of dependency for stroke patients of 9% [27], to a 28 week cost reduction of € 567 [11] Two cost-effectiveness studies showed ... committees which was documented in the trial registration (ISRCTN67636203) This prospective non -randomized controlled cluster trial assessed the cost-effectiveness of three stroke service experiments...
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The impact of a cancer Survivorship Care Plan on gynecological cancer patient and health car provider reported outcomes (ROGY Care): study protocol for a pragmatic cluster randomized controlled trial potx
... Dutch questionnaire Recruitment A pragmatic, cluster randomized controlled clinical trial (RCT) will be conducted, in which 12 hospitals will be randomized to either ‘usual care’ or ‘SCP care’ It ... treatment [8] Although the number of studies that include long-term cancer survivors and their information needs are scarce, results from a few very recent studies suggest that most cancer survivors ... negative effects of the implementation of the SCP in daily clinical practice is lacking As such, both the IOM and Health Council also recommend studies for the evaluation of the impact of SCPs on patient...
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Health education for microcredit clients in Peru: a randomized controlled trial potx
... unless noted otherwise b other supplemental programs, there are few randomized controlled trials to support these claims and more studies are needed to rigorously evaluate whether microcredit offers ... of the CONSORT Group [23], an initiative to promote transparent reporting of parallel-group randomized controlled trials, we have completed the standard CONSORT checklist and flow diagram to provide ... randomization into the treatment or control arm Each regression controlled for the sociodemographic variables listed above Where possible, we also controlled for the baseline value of the outcome variable...
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Support to woman by a companion of her choice during childbirth: a randomized controlled trial potx
... evaluated in controlled studies [5,6] The usefulness of support and the type of support provided by family members, a partner or by friends of the woman have only been evaluated in observational studies ... refused to participate in the study Randomized: 212 105 randomized to receive support from the companion of their choice 105 companions were invited to participate 107 randomized to routine care in ... and on perinatal and breastfeeding outcomes in the twelve hours following delivery Methods A randomized controlled trial was carried out between February, 2004 and March, 2005 at the Sumare maternity...
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Báo cáo khoa học: LRRK2 in Parkinson’s disease: genetic and clinical studies from patients ppt
... screening studies for this mutation worldwide [9] Prevalence of LRRK2 G2019S mutation Most studies have shown that LRRK2 mutations may explain between 5% and 13% of familial and 1–5% of Genetic and clinical ... be a homogenous entity Taken together, the current limited clinical studies of LRRK2 mutation carriers appear to suggest that, although clinically inseparable, there may be subtle differences between ... Journal 276 (2009) 6455–6463 ª 2009 The Authors Journal compilation ª 2009 FEBS 6457 Genetic and clinical studies of LRRK2 U Kumari and E K Tan among Asian races For example, the LRRK2 G2019S substitution...
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Báo cáo khoa học: "Using a Randomised Controlled Clinical Trial to Evaluate an NLG System" doc
... of the Clinical Trial The STOP clinical trial took 20 months to run (of which the first months overlapped software development), and cost about UK£75,000 (US$110,000) We believe the STOP clinical ... as part of the clinical trial Overall, we believe that these small-scale experiments were worth doing, but as a supplement to, not a replacement for, the clinical trial When is a Clinical Trial ... was the source of the 7427 initial smokers mentioned above Results of the Clinical Trial Detailed results of the STOP clinical trial, including statistical tables, have been published in the medical...
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Báo cáo sinh học: "Glutamate carboxypeptidase activity in human skin biopsies as a pharmacodynamic marker for clinical studies" docx
... plasma, and urine) was considered the PD marker of choice to monitor GCP inhibition [19] For clinical studies, the best biological matrix to evaluate CNS/PNS penetration is cerebrospinal fluid ... intestinal tract, and kidney, tissues that are not easily accessible for collection during clinical studies [20] However, local administration of GCP inhibitors have been shown to be analgesic ... Glutamate carboxypeptidase activity in human skin biopsies as a pharmacodynamic marker for clinical studies Journal of Translational Medicine 2011 9:27 Submit your next manuscript to BioMed Central...
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