... minimal long-term risks are preferred Recent years have witnessed a marked improvement in our understanding of the biological factors underlying the development of FL The identification of new targets ... efficacy in treatment of FL and is likely to be even more effective when used in combination with standard chemotherapy B ABT- 737 ABT-737 (Figure 3) was developed in collaboration between IDUN ... ABT-737, this agent does not possess a high affinity for Mcl-1 [45] Oral administration of ABT-263 alone has previously been shown to induce complete tumor regressions in xenograft models of smallcell...
... Residential versus Commercial: Deciding Which Type of Real Estate Is Right for You 21 Chapter 3: Pairing with the Right Agency .41 Chapter 4: Researching and Understanding Your ... in this part gives you tools, systems, strategies and techniques to understand your marketplace and define where you stand in it, and stake your own competitive position In the second chapter, ... that it is Understanding the importance of customer creation over customer service Before you put down this book or send me a note of protest about the title of this section, understand this caveat:...
... than that of cells treated with DNR alone In comparison, there were no any morphological changes for drug-resistant leukemia cells K562/AO2 after treated with DNR alone because of the relevant multidrug ... with DNR alone, scarce cancer cells with weak intracellular fluorescence could be observed The very weak intracellular fluorescence of drug-resistant leukemia cells treated with DNR alone may ... the anticancer drug DNR Our previous study indicates that the presence of bare Au nanoparticles alone could just slightly enhance the uptake of DNR by K562 cells [8] Hence, these results indicated...
... downstream channels at the CPEs Many solutions exist in this framework [10, 11] However, as the VDSL standards usually not assume the use of preamble bits or periodically transmitted training sequences, ... length 300 m, and a tone at frequency around 10 MHz The other parameters are set according to the standards [18, 19]: the transmitted PSD is limited at −60 dBm/Hz and the noise PSD is −140 dBm/Hz ... Throughput loss for one tone corresponding to the obtained signal-to-noise-and-interference ratio (using standard formulas), for a system with 4096 tones and 20 MHz bandwidth Figure 7: Comparison between...
... in mean tumor ADC values after months These results are well in agreement with the current understanding of therapy induced changes assessed by DWI: effective anticancer treatment results in tumor ... G, Spors B, Werk M, Rosner C, et al: CT-guided interstitial brachytherapy of liver malignancies alone or in combination with thermal ablation: phase I-II results of a novel technique Int J Radiat ... Marchal G, et al: Effect of vascular targeting agent in rat tumor model: dynamic contrast-enhanced versus diffusion-weighted MR imaging Radiology 2005, 237:492-499 39 Jordan BF, Runquist M, Raghunand...
... discussions and continuous guidance and assistance, which helped me to shape my ideas and understand my research better A special thanks to Mr Luo Jingnan for providing valuable suggestions on ... least, I would like to thank my parents and my friends for their constant encouragement and understanding I TABLE OF CONTENTS ACKNOWLEDGEMENT I TABLE OF CONTENTS II SUMMARY V LIST OF TABLES AND ... techniques were used to confirm the successful conjugation of the fatty acid to the peptide and to understand its functional attributes A control amphiphilic peptide which differs only in the degree of...
... El Instalador 2000 [10] ASHRAE Standard Project Committee SPC 133; “Method of Testing Direct Evaporative Air Coolers”, ASHRAE, Inc., Atlanta, 1997 [11] ASHRAE Standard Project Committee SPC 143; ... temperature is high, an evaporative cooler cannot succed in reaching the comfort conditions of indoor air alone In many applications, it is combined with another system such as a direct expansion coil (DX), ... Theoretical evaporative cooling process The study of the psychrometric diagram lead to a better understanding of the processes analysed As pointed before, the theoretical process is adiabatic, and...
... incubating the protein at concentrations of 0.1 or 0.4 mgÆmL)1 in NaCl/Pi, pH 7.4, at 37 °C or 45 °C Aliquots were taken over time, and lg protein was loaded on a 7.5% (w/v) nondenaturing gel To avoid ... (middle curve) [tPA] ¼ 20 nM, [wildtype] ¼ lM, [Ser52Arg] ¼ 6.6 lM The upper curve represents tPA alone Results and Discussion The expression of Ser52Arg neuroserpin resulted in a poor yield, with...
... protein analysis Coding regions of full-length ETB and its derivatives were amplified from cDNA by standard PCR techniques, and the fragments were inserted into the expression vector pET21a(+) (Merck ... Heterologous expression of G-protein-coupled receptors: comparison of expression systems from the standpoint of large-scale production and purification Cell Mol Life Sci 60, 1529–1546 Tate CG, Haase...
... three times, lysed in 50 lL Cell Lysis Regent (Promega), and centrifuged at 20 000 g for 10 Aliquots (5 lL) of cell extracts were added to 50 lL Luciferase Assay Reagent (Promega), and the Luc ... for 30 and thawed at 37 °C for min, five times) After centrifugation at 20 000 g for 10 min, aliquots of cell extracts (5 lg protein) were added to a final volume of 125 lL Z buffer (0.2 M sodium ... v/v), kept at °C for 15 min, and vortexed for 15 at °C After centrifugation at 50 000 g for min, aliquots of the supernatant (15 lg protein) were incubated in 25 lL buffer containing 10 mM Tris/HCl...
... productivity with which a nation uses its human, capital, and natural resources – Productivity sets the standard of living (wages, returns on capital, returns on natural resources) that a country can ... Ecuador Indonesia Nigeria Angola Venezuela Iraq 124 Change in Rank, Global Corruption Report, 2007 versus 2003 Note: Competitiveness Master = 2007-11-14.ppt Ranks only countries available in both ... Industries Sophistication of local customers and needs – Strict quality, safety, and environmental standards Availability of suppliers and supporting industries Presence of clusters instead of isolated...
... Structural models depicting this initial stage of infection by bacteria should be allow better understanding of pathogenetic mechanisms of EHEC and EPEC Acknowledgements This work was supported by...
... nanocarriers to non-internalizing receptors may sometimes be advantageous in solid tumours owing to the bystander effect, where cells lacking the target receptor can be killed through drug release at the ... mouse tumour models BR96-doxorubicin showed lower toxicity than that resulting from doxorubicin alone and it was efficacious in these animal models35 However, in dogs, an acute enteropathy (pathology...
... cellular viability an aliquot of cells which receive no treatment were maintained at 37C in the ascites fluid throughout the course of the experiment Viability of this control aliquot was then assessed ... Pharmingen) per manufacturer's protocol To assure cellular viability throughout the assay, an aliquot of untreated VLCs were maintained in culture for the duration of the experiment These untreated...
... line maximally spanning the height of the mouth when fully ajar This truth set served as the gold standard for automatic algorithm evaluation A true positive was defined as the http://www.jneuroengrehab.com/content/6/1/11 ... http://www.jneuroengrehab.com/content/6/1/11 detection of a ROI temporally within the range of frames corresponding to a gold standard mouth opening, and spatially situated within the bounding box defined by the endpoints ... Tu J, Tao H, Huang T: Face as mouse through visual face tracking Computer Vision and Image Understanding 2007, 108:35-40 Steketee J: Spectral emissivity of the skin and pericardium Phys Med Biol...
... order to express only the COX-1 isoform [15] Thus, measured PGE2 levels represent COX-1 activity alone At least three independent experiments were used for data analysis All data are presented ... cells at the concentrations examined (Figure 2A) As shown by Griess assay, incubation with LPS alone markedly increased (about 8-fold) NO production in the cells, compared to that generated in ... situ Nat Med 2003, 9:453-457 Wyss-Coray T: Inflammation in Alzheimer disease: driving force, bystander or beneficial response? Nat Med 2006, 12:1005-1015 Benveniste EN: Cytokines: influence on...
... expectancies of consequences and self-efficacy, etc.) Hence, knowledge from these sciences helps to understand the contributing factors for individuals to use preventive measures or health services even...
... The first rows (8 wells in each row) were filled up with 50 μl of either the standard or control samples There were standards of known IL-6 values, which ranged from the lowest to the highest ... spectrophotometer The reading was printed out and the duplicates averaged out A standard curve was drawn using the values obtained from the standards The control sample ensured that the quality readings obtained ... approval from the institutional animal ethics committee was obtained These rats were housed in standard solid floor cages with wood shaving litter The animals were induced using inhalational...