... provide insights into the origin of its individual enzymes However, the study ofthe enzymes ofthe tricarboxylic acid cycle necessarily also entails the study ofthe several enzymes involved inthe ... compartmentalized inthe glyoxysomes ofplants [31], the single exception being aconitase, which is localized inthe cytosol [32,33] Here we investigate the evolution ofthe enzymes ofthe pyruvate ... complex, the tricarboxylic acid cycle, and the glyoxylate cycle by examining the individual phylogenies ofthe 21 subunits comprising the 14 enzymes of these pathways as they occur in eukaryotes,...
... Cañibano Higher Education in ‘Business Administration’ in Spain HIGHER EDUCATION IN SPAIN WITHIN THE FRAMEWORK OFTHE «EUROPEAN AREA OFHIGHER EDUCATION» As it is well known, the starting point ofthe ... categories of employment From this information, to determine the relative weights of each ofthe subjects ofthe structure in terms of their relevance to the labour market, they requested the opinion of ... Education in ‘Business Administration’ in Spain Regarding the specific subjects, we provide as an example in Table below: a relation ofthe subjects ofthe area of knowledge of «Accounting», distinguishing...
... mechanisms [42,44] The study ofthe effect of pH on enzyme inactivation allows the calculation ofthe pKa ofthe His176 side chain involved inthe inactivation reaction The rate of inactivation exhibited ... nitrogen atoms ofthe backbone ofthe residue preceding the catalytic Cys The conservation of this interaction is suggestive of its Fig The nal model ofthe clostripain catalytic domain The ribbon ... for details) in smaller face The model is ofthe cleaved clostripain lacking the internal nonapeptide The nal residue ofthe resultant a-chain, Arg181, and the rst residue ofthe b-chain, Ala191,...
... demonstrated that the 4-kDa peptide competes with insulin for binding to the 43-kDa protein This suggests that the 4-kDa peptide and insulin bind to the same sites ofthe 43-kDa protein in a similar ... based on the solution structure ofthe biologically active insulin analog, [GlyB24]human insulin, where the orientation ofthe disordered B-chain C-terminal region relative to the rest of molecule ... [32] The proposed model is described as the unlocked state where the B-chain C-terminal b-strand is detached from the rest of molecule, resulting in exposure ofthe insulin pharmacophore to the...
... glycosylation These findings are intriguing given that these three cysteine residues are absolutely conserved not only inthe F proteins of other Pneumovirinae, but also inthe F proteins ofthe Paramyxovirinae ... To determine the contribution ofthe individual cysteine residues inthe extracellular domain (ECD) to its functions, a panel of mutations in which each cysteine residue inthe ECD ofthe HRSV ... cysteine residues inthe extracellular domain in protein expression and cell fusion ofthe HRSV F protein and represents the first analysis ofthe contribution ofthe cysteine residues of the...
... components inthe bearing couple when revising for this indication While it is too early to comment on the clinical outcomes of these prostheses, the main determinants of success in these patients ... bearing These should theoretically confer increased range of movement theoretically allowing a higher level offunction Prior to having their primary procedures these patients were all involved in ... absence of infection Cystic lesions were noted behind the acetabular component in cases but the cup was grossly loose in only one of these There was evidence of gross collapse of a segment of the...
... components inthe bearing couple when revising for this indication While it is too early to comment on the clinical outcomes of these prostheses, the main determinants of success in these patients ... bearing These should theoretically confer increased range of movement theoretically allowing a higher level offunction Prior to having their primary procedures these patients were all involved in ... absence of infection Cystic lesions were noted behind the acetabular component in cases but the cup was grossly loose in only one of these There was evidence of gross collapse of a segment of the...
... linear regression analysis by plotting the specific binding ofthe radioligand on X-axis and bound/free on Y-axis The maximal binding is a measure ofthe total number of receptors present inthe ... half the specific binding was defined as EC50, which is same as IC50 The affinity ofthe receptor for the competing drug is designated as Ki and is defined as the concentration ofthe competing ... data was analysed according to Scatchard, 1949 [35] The specific binding was determined by subtracting non-specific binding from the total The binding parameters, maximal binding (Bmax) and equilibrium...
... the initial rate of qE, which is much slower in lut2.1 The PSII antenna size was determined by measuring the half time inthe rise of chlorophyll fluorescence inthe presence ofthe photosynthetic ... violaxanthin was supplied inthe absence of lutein, a violaxanthinbinding complex was obtained which did not produce trimers For the first time, our measurements show that the binding of lutein per ... previous findings [23] Inthe case of band from lut2.1, the resistance to photobleaching was, surprisingly, only slightly higher than inthe case of WT, although the LHCII content was much higher (the...
... changes inthe airway The first step of assessing the potential importance of these cells inthe inflammatory process would be to assess their numbers and function within the airways Therefore, in ... this study we have extended the findings of our previous study to investigate, within induced sputum, the number and cytotoxic functionofthe three main classes of human killer cells; CD8 + ... Glucocorticosteroids The Nottingham Local Research Ethics Committee approved the study protocol and written informed consent was obtained from the 26 subjects before entering the blinded study Of these, the 11...
... EJ: Cystatin C improves the detection of mild renal functionin older patients Ann Clin Biochem 2003, 40:648-655 Den Hollander JG, Wulkan RW, Mantel MJ, Berghout A Is cystatin C a marker of glomerular ... declare that they have no competing interests References 532 Villa P, Jiménez M, Soriano MC, Manzanares J, Casasnovas P: Serum cystatin C as a marker of acute renal dysfunction in critically ... thyroid-stimulating hormone, which confounds extrapolation of published data in this population We feel that future studies to evaluate this issue are warranted Competing interests The author(s)...
... motifs Strengthening the PY tract eliminates the role ofthe C-rich motifs We next investigated the role ofthe PY tract in LCAT intron splicing We mutated the PY tract to determine whether the C-rich ... lower affinities Binding of U2AF65 to low-scoring PY tracts In order to asses the relationship between the S65 score and observed U2AF65 binding affinities, we evaluated the binding of recombinant ... eliminates the role ofthe C-rich motifs Strengthening the PY tract eliminates the role ofthe C-rich motifs (a) LCAT intron with the mutations shown in blue above the WT sequence BPS, branchpoint...
... 1.10.5.1 Sphingosine kinases and S1P inthe brain 28 1.10.5.2 S1P receptors inthe CNS 29 1.10.5.3 Role of Sphingosine kinases and S1P in neurodegeneration 30 1.11 Aims ofthe present ... underlying the cause of Parkinson’s disease (PD) has attracted the attention of manyresearchers inthe last few decades In spite ofthe recent technical advances inthe field of neuroscience, the ... implicated in PD pathogenesis, the expression pattern of TNFα and iNOS inthe SNc ofthe MPTP-induced mouse model was analysed It was observed that there was an increase inthe levels of XX TNF and iNOS...
... recession, i.e the position ofthe gingival margin with respect to the cement enamel junction (CEJ); • CAL (clinical attachment level): i.e the position ofthe attachment in relationship to the CEJ; ... Considering that no previous report exist reporting on the use of EHA combined with autologous bone but without the application of a membrane inthe treatment of infra bone defects, our clinical ... encouraging considering that in a similar study a mean value ofthe increase ofthe bone height of 0.5 mm was obtain with membrane application [31] CONCLUSIONS All these properties make HA useful in...
... task, then it is not only confined to the Ministry of Labour or Ministry of Education and Training, it is also concerned with human resource planning inthe Ministry of Planning or Ministry of Finance ... and teaching has helped Vietnam inthe new era of integration On the other hand, the learning and teaching of English at the expense of other languages is posing serious issues We should first ... what are their education and training levels etc It is largely concerned in determining what training needs there are so that the labour supply can be shaped to meet the demands ofthe economy...
... the central area for the purpose of resettlement Generally, getting along with the rapid expansion, the east bank ofthe Red River exhibited the beginnings of urbanization The south-west ofthe ... components: Bac Linh Dam (North of Linh Dam), Linh Dam peninsula inthe middle and Linh Dam expansion (South of Linh Dam) The success ofthe project has set the stage for a series of New Towns that ... tropical climate Among these, the outstanding point is the area of highstorey apartments and office buildings inthe center of Linh Dam peninsula, surrounding by low-storey buildings, parks, open...
... nặng nhọc với mức thu nhập thấp, kéo theo điều kiện sống mức tối thiểu, tạm bợ khu nhà trọ rẻ tiền với điều kiện sinh hoạt an ninh không đảm bảo Đời sống tinh thần lao động hạn chế Họ thấy cô ... làm việc chợ lao động thuê trọ theo ngày (đêm), lại thuê nhà theo tháng Có khoảng 22,86% nữ lao động tự phải sống nơi có điều kiện sinh hoạt không đảm bảo, vệ sinh; 40,95% không sử dụng nước ... vật chất, tinh thần lao động nghèo nàn Họ thường tiêu tiết kiệm cho khoản chi phí sinh hoạt thiết yếu Có 22,86% nữ lao động tự phải sống nơi có điều kiện sinh hoạt thiếu thốn, vệ sinh Họ thường...
... that The prevailing direction of wind fall is from the north-west (NW) i.e (315°-00) which is more than 70 % of all the time The frequencies of wind coming from the remaining sectors are insignificant ... average value of wind speed inthe North zone of Iraq during any calendar year A histogram ofthe wind direction measurements for the site of Tuz during this windy month is shown in Figure From ... preparation The northern area of Iraq (the area selected in this study) is considered transition zone because it located between mountain inthe extreme north east and the opening plains inthe south,...
... five definitions, in spite of slight differences inthe expressions, share common features that they all emphasize the importance of finding the closest equivalence in meaning by the choice of appropriate ... inthe translation of exhibit labels inthe Vietnam Museum of Ethnography (VME)? II SCOPE OFTHE STUDY There are several types of exhibit labels in a museum: title or headline labels giving the ... not reflect the role ofthe speaker ofthe House of Commons as an independent person who maintains authority and order in Parliament (b) The SL concept is not lexicalised inthe TL The SL word...
... AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OFTHE USE OF THIS SOFTWARE, EVEN IF ADVISED OFTHE POSSIBILITY ... practically speaking, this means inthe context ofthe user launching the code Good practices include making certain that administrative accounts are kept to a minimum, that administrators use ... developed using script embedded inthe body ofthe email message that executed as the message was rendered for viewing by the client Finally, the recent ILOVEYOU worm was similar in concept to the Melissa...