... analysis, interpretation of data, and writing of this report HPH, DK and TF contributed to the study design, interpretation of data, and added scientific input to this report in form of comments ... Collaborating Centre for Mental Health, National Institute of Clinical Excellence): Schizophrenia: Core interventions in the treatment and management of Schizophrenia inprimaryand secondary care Clinical ... properties of the respective substance and the patients individual risk factors The prevalence of MetS in the FAS of 42.8% (AHA/ NHLB definition) at baseline was comparable to the findings from...
... Patientswith respiratory, cardiac disease - Patientswithcirrhosis has pleural effusion - Patients deny and uncooperative study Patientsand methods Child-Pugh classification of severity of liver ... Ghi hình phổi Tech 99m gắn Albumin CT Scanner XQ tim phổi Chụp ĐM phổi Patientsand methods Patients Criteria were required for inclusion in the study: Diagnostic cirrhosis: - Impaire liver cell ... - Clinical, laboratory, endoscopy and radiologic manifestations were not adequate: laparoscopic or liver biopsy Patientsand methods Criteria were excluded for inclusion in the study: - Patients...
... majority ofpatients (79%) had HTN and 27% had DM CVD was prevalent in 35% ofpatients A total of 62% were on angiotensin converting enzyme inhibitors (ACE-i), 30% on beta blockers and 53% on statins ... challenges in predicting and treating patients early in course of CKD to positively alter patient outcome There is definitely a high prevalence of traditional risk factors like HTN, DM and DLP in chronic ... occurrence of de novo vascular events in this population (27) In a recent study C-reactive protein and low albumin has been shown to be the predictor of morbidity and mortality in CKD 3-5 patients in...
... fitness of the final model was good in terms Table Sites and methods of diagnois of extrapulmonary involvement in 40 patients Involved organ* Miliary involvement Lymph node Intestine Larynx Soft ... organ involvement inpatientswith pulmonary TB was more common inpatientswith bilateral lung involvement but without cavity formation or low levels of serum albumin Clinicians should keep in mind ... one organ involved, all of them were counted independently; � patientswith intestinal TB diagnosed based , on typical colonosopic findings and the other patientswith TB laryngitis without AFB...
... and 24 hours neuroserpin levels was defined as neuroserpin decrease All determinations were carried out in a laboratory blind to the clinical outcome and neuroimaging findings Endpoints The primary ... Neuroserpin was used as a continuous variable since there was a linearity of the odds ratios for outcome The influence of neuroserpin decrease at 24 h on serum levels of molecular markers of brain injury ... therefore, a total of 129 patients were finally included in the study This research was carried out in accordance with the Declaration of Helsinki of the World Medical Association (2000) and approved...
... and 24 hours neuroserpin levels was defined as neuroserpin decrease All determinations were carried out in a laboratory blind to the clinical outcome and neuroimaging findings Endpoints The primary ... Neuroserpin was used as a continuous variable since there was a linearity of the odds ratios for outcome The influence of neuroserpin decrease at 24 h on serum levels of molecular markers of brain injury ... therefore, a total of 129 patients were finally included in the study This research was carried out in accordance with the Declaration of Helsinki of the World Medical Association (2000) and approved...
... HRQOL domain scores when re-treated with a combination of interferon alpha-2b and ribavirin Compared to the baseline, the responders sustained a significant decrease in the domain score of vitality ... arms in terms of the HRQOL scores at base line (data not shown) Table 2: Baseline SF-36 norm based Domain scores in refractory HCV patients undergoing re-treatment with peg interferon alpha 2b and ... effect of interferon alfa and ribavirin combination therapy in naïve patientswith chronic hepatitis C J Hepatol 1995, 23:S8-12 Poynard T, Marcellin P, Lee SL, Niederau C, Minuk GS, Ideo G, Bain...
... therapeutic intervention [13,14] In a clinical trial, the knowledge of instrument’s responsiveness helps in the selection of measures, in setting the correct sample size and assists in prioritising the ... self-rating questionnaires and the patient’s overall assessment of his/her change in state of health is observed inpatients receiving chemotherapy but only with the QLQ-C30 Indeed, measurements of ... Results Sociodemographic and clinical data Between April 2003 and February 2007, 127 patients were enrolled in the study: 71 patientsin the chemotherapy group and 56 patientsin the radiotherapy...
... manuscript including extensive revision of interpretation and discussion of the results AN and RRP reviewed the methodology, contributed to recruiting patients, confirming the diagnosis and interpretation ... is part of the PGI battery of brain dysfunction, developed at PGIMER, Chandigarh, India The battery is administered in Hindi, the first language of most subjects, and has been developed and validated ... was involved in the conceptualization of the study, literature review, recruiting patients, data collection, statistical analysis and interpretation of results PBM was involved in review of the...
... afford greater insight in describing and grading the impact of side effects associated to antipsychotic drugs [15,16] A brief instrument is preferred for use in clinical practice andin investigations ... UK: National Institute of Mental Health in England; 2005 Thornicroft G, Tansella M: Growing recognition of the importance of service user involvement in mental health service planning and evaluation ... males (n = 151) Sociodemographic and clinical characteristics of the sample are shown in Tables and The percentage of missing values in each of the items contained in the questionnaire was less...
... cytokine a prime candidate also in the pathogenesis of SS Increased serum levels and salivary gland expression of IL18 inpatientswith SS is in keeping with an active role for this cytokine in ... level was detected in all SS patients studied, but interestingly only in a minority ofpatientswith chronic sialoadenitis No staining for IL-18 was found in acinar cells, indicating that IL-18 production ... syndrome (SS) in salivary gland ofpatientswith Sjögren's syndrome (SS) Paraffinembedded sections were double-stained for CD3 (brown) and CD20 (purple) (a–c) and single-stained with CD21 (d) Inflammatory...
... (77.9%) ofpatients was still being actively treated with DMARDs at 30 months Interestingly, despite blinding of their treating physicians, the patientswith anti-Sa and anti-CCP were treated as intensively ... the single serological marker independently predictive of poor outcomes and, together with the presence of joint erosions at inclusion andwith increasing age, characterized a subgroup ofpatients ... coordinating nurses and treating physicians remained blinded to the patients' HLA-DR, anti-CCP and anti-Sa status Serum and DNA materials were coded to ensure confidentiality and blinding of investigators...
... for inflammation of the joint capsule of the left SI joint, which was present in only three patients Table summarizes the concordant findings of both readers with respect to inflammation and ... assessment ofpatientswith early inflammatory back pain It is the amount of variation in the outcome of interest (inflammation and/ or structural changes) rather than the number ofpatients under ... joints inpatientswith early inflammatory back pain Assessing bone marrow and/ or subchondral bone enhancement suffices to detect inflammation Inflammation in the joint space, the joint capsule and...
... gender, and race withpatientswith RA (early and long-standing disease combined) These patientsand control subjects are part of an ongoing cohort study to identify cardiovascular risk factors in ... differences in the Framingham risk score inpatientsand controls, and the majority of the SLE patientswith coronary calcification had a low 10-year risk according to the Framingham calculations [12] In ... subjects, independent of Framingham risk scores (odds ratio = 2.46, 95% confidence interval 1.20 to 5.05) Discussion The two primary findings in this report are that patientswith long-standing RA...
... one-fifth of the total at years The number ofpatientswith a flow ratio between 25% and 75%, became smaller and the number ofpatientswith a flow ratio >75% (and exceeding 100%) became larger in time ... combined with parotid salivary output ofpatientswith head -and- neck malignancies treated with RT We found a deterioration of most of the QOL items after completion of radiotherapy compared with ... http://www.ro-journal.com/content/2/1/3 Table 2: Mean scores of the scales and single items of questionnaire for patientswith cancer of the head- and- neck treated with radiotherapy with or without surgery A significant outcome...
... cannabinoid CB1 and CB2 receptor protein and RNA and the endocannabinoids AEA and 2-AG are present in the synovia ofpatientswith end-stage OA and RA The presence of increased levels of AEA and ... percentage of expression of the internal control, β-actin Data are presented as mean ± standard error of the mean of the expression of CB1 and CB2 protein in four OA and four RA patients, assessed in ... summarised in Table Patients were told to stop taking aspirin and all cytokine inhibitors 10 to 14 days prior to surgery Histology of synovial biopsies and levels of cytokines Haematoxylin and eosin...
... inflammation and cartilage degradation were inhibited by blocking IL-1β but not IL-1α In RA patients, IL-1β is overexpressed in inflamed synovial tissue, in particular in the lining layer andin sublining ... (IL-1Ra; anakinra), which binds to the IL-1 receptor without eliciting a signal and therefore competes with the binding of the two natural ligands, namely IL-1α and IL-1β As compared with TNF-α inhibitors, ... Scoring was performed on decoded slides by two separate observers, using the following parameters In the haematoxylin/eosin stained slides the amount of cells infiltrating the synovial lining and...
... age and height The methodological features of all randomized clinical trials most relevant to the preventionof bias (including the Jadad criteria of randomization, blinding and completeness of ... counted in our nine studies included two cases of hemorrhagic cystitis [17] and several cases of hematuria – one case in Valentini and colleagues [18], two cases in Hoyles and colleagues [10] and nine ... of an adverse event occurring in the CYC group compared within the non-CYC group Two of the three randomized clinical trials reported the FVC and DLCO value at baseline and after 12 months in...
... file) Insulin resistance was evaluated from fasting glucose and insulin using the Homeostasis Model Assessment of Insulin Resistance (HOMA IR) [30] and the Quantitative Insulin Sensitivity Check Index ... In that study, UA was shown to associate with renal dysfunction inpatientswith RA In this study, we focus on the potential association of UA with renal dysfunction inpatientswith RA and investigate ... expensive, timeconsuming and not easily applied in large cohorts such as this Conversely, 24-hour urine collections for determining creatinine clearance are inaccurate and are being abandoned Estimated...
... improvement in clinical signs and symptoms, physical function, and HRQOL inpatientswith active AS [16,32] Maintenance of improvement Page of 12 (page number not for citation purposes) in clinical ... to measure the severity of fatigue, spinal and peripheral joint pain, localized tenderness, and morning stiffness inpatientswith AS The final BASDAI score has a range of to 10; a lesser number ... BASFI and SF-36 PCS scores, both indicating impact on physical functioning and well-being for up to three years These effects were also clinically meaningful The remaining HRQOL outcomes, including...