... conceptual model of relapse management and pool of potential scale items Second, this pool of items was administered by postal survey to 160 people with relapsing-remitting MS, and standard psychometric ... and development of scales A total of 379 questionnaires were posted and 296 people responded Of these, 136 people responded by saying Item analysis and scale development A total of 112 items from ... the standard error of measurement, an indication of the amount of variation or spread in the measurement error, is relatively low Validity (Table 4) The direction, magnitude and pattern of correlations...
... refers to the pace of clinical evolution of the patient, and AKI ‘trend’ refers to the rate of clinical and/ or biochemical changes (including urea and creatinine) [16] The objective of this algorithm ... volume of distribution, degree of protein binding, and water solubility It is beyond the scope of this review to discuss details of indications and/ or prescription of EBP for overdoses/intoxications ... to standardize the diagnosis, classify the severity and monitor progression of AKI Importantly, they were also designed to enable better comparison of clinical studies on the epidemiology and...
... initiation in severe AKI and prognoses Timing of RRT was assessed by several approaches such as median value and median change of BUN and sCr, and the period from ICU admission to start of RRT Contrary ... conception and design, and drafted the manuscript WYL, DMH, SLL and PRT were involved in acquisition and interpretation of data YFL, GHY, and CHW participated in the sequence alignment and drafted ... high-flux filters (Hemofilter, PAN-10, Asahi Kasei, Japan) and HF 400 (Informed, Geneva, Switzerland) The hemofiltration flow and blood flow blood flow were 35 ml/ kg/hour and 200 ml/min, respectively...
... oligo-anuria and acidosis at time of initiation of RRT and pre-existing chronic illnesses were independent risk factors for ICU and hospital mortality • Failure to correct acidosis and development of more ... urea cut-off of 24.2 mmol/L (as per Bagshaw and colleagues [11]) did not differentiate between survivors and non-survivors either Univariate analysis showed that at the time of initiation of RRT, ... less; platelets of 20,000 cells/mm3 or less; haematocrit of 20% or less The objectives of this study were twofold Firstly, to describe the epidemiology of ICU patients treated with RRT and to compare...
... conventional renal criteria (creatinine and diuresis) are a poor reflection of AKI and not differentiate between pre-renal failure and intrinsic renal damage Early initiation of RRT in pre-renal failure is ... Oudemans-van Straaten HM, Tijssen JG, Zandstra DF, Kesecioglu J: Effects of early high-volume continuous venovenous hemofiltration on survival and recovery of renal function in intensive care patients ... therapy Author details Department of Intensive Care, Academic Medical Center, University of Amsterdam, PO Box 22660, 1100 DD Amsterdam, the Netherlands Department of Critical Care, Western Sussex...
... cohort and/ or randomised/quasi-randomised clinical trial (RCT) design; 2) adult critically ill population; 3) diagnosis of AKI; 4) description of factors related to timing of initiation of RRT; and ... as randomised? Yes Yes Was the method used to randomise described and appropriate (table of random numbers, computer generated, and so on)? Yes No Was there a description of withdrawals and dropouts? ... meta-analysis of 15 unique studies compared “early” versus “late” initiation of RRT Figure Funnel plot of all 15 studies X-axis is log of risk ratio of death Y-axis is Standard error of Log Risk ratio of...
... of HAART [4], yet data conflict with regard to CD4 count cut-offs and consequences of the immune reconstitution syndrome [5] In this study, we compare the clinical treatment outcomes of HIV and ... counts of
... response of both mtDNA and CD levels than 4.5 Gy Significant inverse correlation was found between mtDNA content and CD level at 4.5 and Gy (P = 0.037 and 0.048) Moreover, mtDNA content of lymphocytes ... mean of 39.4 ± 10.5 Of these, 10 are females and 16 males Besides, a total of 39 healthy volunteer individuals without IR were included in this study for comparing the difference of basal mtDNA and ... plasmid-constructed ß-actin, HVR2 and CD standards were used in each run of real-time PCR Of these, both plasmids containing the CD breakpoint and the HVR2 region were kindly provided by Professor E Kirches...
... before the onset of NHL An important feature of our cohort was the finding of symptomatic NHL occurring in the setting of profound HIV viral load decline following initiation of HAART This phenomenon ... to all of the data, carried out acquisition, analysis, and interpretation of the data, drafted the manuscript, supervised the study, and takes responsibility for the integrity of the data and the ... demographic information, including median age and sex, and baseline median values of CD4 and log 10 VL, were calculated using a Mann Whitney test Mean change in CD4 and log10 VL in NHL cases compared to...
... premolar, and the right mandibular second premolar, #2 Tooth stumps of the left maxillary canine and second premolar, and the right mandibular first premolar, #3 Dental caries of the right maxillary ... periodontitis and gingival abscess of the right mandibular lateral incisor, #2 Dental caries of bilateral mandibular central incisors 105 Depression, Hypertension, Osteoarthritis of the spine, ... Science and Technology of Japan, and was supported in part by Health and Labour Sciences Research Grants for Research on Hepatitis from the Ministry of Health, Labour and Welfare of Japan 12 13 14...
... (etanercept) achieved a ΔDAS28 of 1.22 and ΔCD3 of 19, and Patient (anakinra) achieved a ΔDAS28 of 0.16 and ΔCD3 of -118 There was a significant correlation between ΔCD3 and ΔMRI synovitis following ... moderate responder (Patient 1) and non-responder (Patient 2) A and B are baseline and Week 12 images of Patient 1, and C and D are baseline and Week 12 images of Patient respectively Over the ... the conception and design of the study and coordinated the arthroscopies OF conceived of the study, participated in its design and coordination and has been involved in the revision of the manuscript...
... pregnancy and the different variables of fetal development On the one hand, there was a lower prevalence of maternal infusion in the group of total CAs, and within them, of hypospadias and multiple ... in 88.4% of cases and in 93.8% of controls The informed consent document was signed by 98.4% of case mothers Personal identifiers (i.e name and address) were deleted from the record of cases ... distribution of infusions between controls and cases (χ28=7.55; p=0.48) and in the frequency of infusion during the second-third months of pregnancy (χ21=0.4; p=0.51) The reason of infusion for...
... the mythus of its birth, told of the power of the sun-light that spread out its delicate leaves, and forced 65 of 260 them to impregnate the air with their incense— and then he thought of the manifold ... clouds While he thought of this andof the whole metamorphosis he had undergone, he smiled and said, ‘I sleep and dream; but it is wonderful how one can dream so naturally, and know besides so exactly ... answer at hand Come, let us be men!’ ‘O warm spicy land of my birth,’ sang the Canary bird; ‘I will sing of thy dark-green bowers, of the calm bays where the pendent boughs kiss the surface of the...
... when lists of devices are being used One such situation is the output of lspci (part of the pciutils package, available with most distributions) and the layout of information in /proc/pci and /proc/bus/pci.[55] ... independence is often a goal in the design of a computer bus, and it's an especially important feature of PCI because the PC world has always been dominated by processor-specific interface standards ... to this aim Using those identifiers, you can detect and get hold of your device With version 2.4 of the kernel, the concept of a PCI driver and a specialized initialization interface have been...
... Suppression of postsynaptic density protein 95 expression attenuates increased tyrosine phosphorylation of NR2A subunits of N-methyl-D–aspartate receptors and interactions of Src and Fyn with ... (albumin) and 110-kDa bands are shown with arrows (C) Electron microscopy of the G ⁄ E fraction that was purified and processed as described in Experimental procedures Note the presence of typical ... analysis of c-Src and DPP IV (80 lg protein; 7.5% resolving gel) using anti-c-Src and anti-DPP IV (26C) IgG (pieces of the same membrane) DPP IV signals are expressed as a percentage of the maximal...
... isoform (Isoform A) and no traces of the shorter isoform (Isoform B) By contrast, the expression of only Isoform B was detected in the cells transfected with the p28LT4 construct (Fig 2B) and ... trypsinogen 4, both Isoforms A and B were detected The exclusive interpretation of this experiment is that the generation of Isoform B of trypsinogen occurs at the level of translation and not post-translationally ... expression level of Isoform B with the wild-type CUG initiation codon was lower than that of Isoform A (expressed together with Isoform B) (p72MT4-GFP versus p28LT4-GFP; Table 1) and was dependent...
... 3.2 Sunderland’s classification Early work of Sunderland brought about a much deeper understanding of the nerve ultrastructure (Sunderland, 1947, Sunderland and Bradley 1949) This offered an ... of these types of pathophysiologic change, however an injured nerve is composed of thousands of axons, and a mixed pattern of segmental demyelination and axonal loss is manifested A precise and ... of a specific beta-tubulin isotype.” Proceedings of the National Academy of Sciences of the United States of America 85 (12) (June): 4530-4533 Hoffman, P N, D W Cleveland, J W Griffin, P W Landes,...
... role in determining both the level of expression and the location of the start of transcription of PS1 In the Ets family of transcription Ó FEBS 2004 Regulation of the presenilin gene (Eur J Biochem ... Pastorcic and H K Das (Eur J Biochem 271) Ó FEBS 2004 Fig Deletion mapping of the PS1 promoter The positions of the 5¢- and 3¢-ends of each deletion fragment are indicated on the left (5¢D) and on ... Regulation of the presenilin gene (Eur J Biochem 271) 4489 A Fig Effect of PS1 promoter point mutations on the efficiency of transcription initiation and 23 the position of the start site(s) (A) Effect of...
... with BSA as a standard (Biorad, Munich) DNA polymerase a and DNA primase assays were performed as previously described [34,42,43] Preparationof S100 extracts and replication of SV40 and JCV in vitro ... beforehand with a primase assay on poly (dT) Lanes and 2, control reaction with DNA polymerase a-primase lacking TAg or vice versa; lanes and 4, 0.2 U and 0.4 U of human; lanes and 6, 0.2 U and ... incorporation of radioactive dNMP was measured by acid-precipitation of DNA and scintillation counting The total radioactivity was measured after spotting lL of a 200-fold dilution of the replication...