... clinical course of our case, with the appearance ofcervicallymph node metastases after four years of follow-up, supports the approach of Goode and Corio [10] The prognosis of oncocytic carcinomas ... number of studies have reported multiple recurrences of this tumor and regional or distant metastases [2,6,8-10] The cervicallymphnodes may be affected as with other malignant tumors of the ... Page of Figure A) Computed tomography image four years after first surgery revealing a cervicallymph node enlargement (red arrow) B) Histopathological study ofcervical specimen showing metastatic...
... with at least of the following symptoms: relieved with defecation associated with change in frequency of stools Associated with change in form of stools and two or more of the following symptoms: ... trial of IBS patients with long-standing symptoms and no responseto conventional medical treatment found psychotherapy superior to medical treatment in reducing bowel symptoms( diarrhea and abdominal ... pathogenesis of IBS A number of motor abnormalities have been described in the colon and small intestine of IBS patients Patients with predominant symptom of diarrhea seem to have accelerated whole gut and...
... V600E and V600K mutations Our preclinical data demonstrating similar kinase activity of the V600K and V600E mutations, together with clear evidence of clinical activity of PLX4032 in a patient with ... biopsy of a cutaneous lesion was tested and shown to be positive for the BRAF V600E mutation The patient was treated and achieved an excellent clinical responseto PLX4032, associated with substantial ... burden and pain from the lesions Figure shows the cutaneous lesions before and after treatmentwith PLX4032 A portion of the tumor was also collected for laboratory research studies according to...
... correlates with the potential to execute necrosis in responseto treatments with glycolytic inhibitors In contrast, the bioenergetic signature directly correlates with the apoptotic responseto 5-FU treatment ... represents an index of the relative relevance of cellular energy provision pathways [9,11], and the potential to execute cell death in responseto the metabolic inhibitors, 3BrP and IA, and the anti-metabolite ... treatmentof G-, M- and especially SM-cells resulted in a significant percentage of annexin-positive stained cells compared to controls (Figure 2), suggesting induction of apoptosis in responseto 5-FU...
... correlates with the potential to execute necrosis in responseto treatments with glycolytic inhibitors In contrast, the bioenergetic signature directly correlates with the apoptotic responseto 5-FU treatment ... represents an index of the relative relevance of cellular energy provision pathways [9,11], and the potential to execute cell death in responseto the metabolic inhibitors, 3BrP and IA, and the anti-metabolite ... treatmentof G-, M- and especially SM-cells resulted in a significant percentage of annexin-positive stained cells compared to controls (Figure 2), suggesting induction of apoptosis in responseto 5-FU...
... CT and TT) and alleles (C and T) with patient’s baseline characteristics including patient’s age, gender, specimen histology, stage of the disease and presence or absence of B-symptoms (Table and ... regression ofnodes on CT of more than 1.5 cm in their axial diameter to less than 1.5 cm, andnodesof 1.1-1.5 to less than cm Relapsed disease (RD) was defined as: 1) the appearance of any new ... histology, disease stage and presence or absence of Bsymptoms (Table 5) None of these factors were associated with clinical response in HL patients (P value > 0.05) Table shows the genotype and...
... production of cytokines, specialized cytokines called chemokines and cell adhesion molecules [9] Chemokines belong to a superfamily of cytokines that promote chemotaxis of leukocytes to areas of infection, ... result of sepsis are felt to play a central role in the development of ARDS Migration of Experimental protocol Four hours after endotoxin or saline, the rats were sedated and anesthetized with ... Comparison of mRNA, plasma and lavage concentrations of MIP-2 in the control, neutropenic, endotoxemic and neutropenic, endotoxemic groups * Plasma MIP-2 is higher in endotoxemic rats compared to control...
... Figure Expression of apple PR genes in responsetotreatmentwith SAR elicitors Expression of apple PR genes in responsetotreatmentwith SAR elicitors Northern hybridization of RNA preparations ... induction of PR genes in apple in responsetotreatmentwith elicitors of SAR is questionable, at best Our studies of PR gene expression in shoots following treatmentof 1-year-old apple trees with ... at each time point Elicitor treatment Elicitors were sprayed to run-off using a hand-pumped atomizing sprayer Elicitors were diluted in water and were applied to hours into the light cycle INA...
... necrosis factor (TNF) blockade and clinical responsetotreatment Patients were divided into two groups (ratio < and ratio > 1) on the basis of their IFN response upon TNF blockade and compared with ... [28,29] From a total of 18 of the 33 patients we studied, levels of anti-citrullinated protein antibody, rheumatoid factor, and double-stranded DNA autoantibody, determined before and 24 weeks ... clinical responsetotreatment Finally, we investigated whether the treatment- induced changes in type I IFN response gene expression levels were associated with clinical responseto treatment...
... between the responses of multiple genetic groups of chickens to mitogens Concavalin A and PHA or mixed lymphocyte reaction, and MD susceptibility In this study, correlations between resistance of several ... easier to measure as wattles tended to be soft and pliable Of the doses tested, 500 and 1250 mg gave similar swelling responses in the wing web The procedure used in exp was similar to that of Van ... levels ofresponseto PHA in this study were lower than those observed by Van der Zijpp (1983) and Lamont and Smyth (1984) This discrepancy may be due to the lower dose of PHA and older age of the...
... 50 mm, and height of 20 mm at a bulk density of 1.53 g/cm3 The acrylic rings were filled up to a height of 20 cm Degassed water was poured onto the top of the column at a rate of 1.0×10-3 to 2.0× ... mixed with gypsum at application rates of 0.5 wt% and 1.0 wt% Alkali soil and gypsum were mixed uniformly and were packed in an acrylic ring with an outer diameter of 60 mm, inner diameter of 50 ... Inoue and Shiozawa (Inoue and Shiozawa, 1994) In our research, a four-electrode sensor was used as an indicator of the total salt concentration in the soil column, to observe the runoff rate of...
... eutrophication of West Lake by biomass of phytoplankton Biomass of phytoplankton is an indicator of eutrophication, so it is possible to estimate and especially predict eutrophication by phytoplankton model ... model of phytoplankton with a variety of major components of lake ecosystems: dB p / dt = ( Pnet , p − G p, z − U p − M p ) B p , where Bp: biomass of phytoplankton; Pnet,p: growth rate of phytoplankton; ... rate of phytoplankton; Gp,z: rate of grazing phytoplankton by zooplankton; Up: rate of settlement, Mp: rate of mortality without zooplankton After combining the data of West Lake and CLEAN model,...
... combination with the inspection of the structural models In the light of this achievement, we have applied a similar approach Predictionof p53 mutant severity to p53 to arrive at an automated method ... corresponds to residues with conserved properties and has a value of 0; ‘.’ corresponds to semiconserved properties and has a value of 0.5; if no similarity exists, the parameter has a value of If ... classified correctly in 85% of cases and Table Effect of cut-off value on the prediction accuracy The prediction accuracy, specificity, sensitivity, number of mutants classified and MCC values on training...
... fluctuation between PC and phytoplankton mass - The content of Pzoo: alters over time, comparing to change of PC shows that the vibration amplitudes of zooplankton and phytoplankton are the same But ... sources of phosphorus include: 1) Diffuse sources: 117 - The amount of P loads from basin (P1) is related to the type of land, land use and intensive cultivation of agricultural land - The amount of ... where: A is the total amount of nutrients loading from basin; X1,X2, ,Xn: areas of the forms of land use and the land use methods 1, 2, ,n; a1,a2, ,an: exporting coefficients of phosphorus 2)...
... view of the thermocline and upper ocean density field and variability on time scales of weeks and longer Notwithstanding the shift in emphasis towards profiling, the floats’ displacement vectors ... obvious solution to this will be to replace the wire with an acoustic altimeter, a device that measures the distance to the bottom, and a pump to adjust its buoyancy to stay within a certain ... be to adapt the technology to studies of circulation in shallow seas and continental shelves such as the Gulf of Maine and the North Sea To so floats will have to operate in shallow waters with...
... incontinence) and search (quality of life and bother and urinary Results of search (quality of life and distress and urinary incontinence) and search (quality of life and bother and urinary incontinence) ... related to symptoms of UI [19] The long form of the UDI consists of 19 questions and total scores are converted to a score range of 0–300, with higher scores representing greater symptom distress ... treatment for UI found that severity of symptoms was the most important predictor of QoL and bother [8] Assessment of severity of symptoms, degree of distress or bother, and impact on QoL has not been...
... TST of ≥ 10 mm and 59.6% a positive IGRA when screened in the scope of this study (Table 5) Eight HCWs had active TB at the time of screening, and progression to active TB within to 24 months of ... Profession and risk assessment were not associated with TST or IGRA results The number of years working in healthcare increased the probability of positive TST and Torres Costa et al Journal of ... IGRA increased with diameter in TST However, 42.4% of the HCWs with a TST of ≥ 20 mm were negative in IGRA and 11.2% with a TST of < mm were positive in IGRA Age is a risk factor for a positive...
... distribution of background pain intensities as measured by VRS (A) and NRS (B) and scatter plot * of the two measures (C) Detailed legend: *In order to avoid an high number of points plotted on top of ... distribution of peak pain intensities as measured by VRS (A) and NRS (B) and scatter plot (*) of the two measures (C) Detailed legend: (*) In order to avoid an high number of points plotted on top of each ... high variability of VRS formulations both in the number ofresponse categories and in the labels attached to these categories, support the use of NRS which is applied with more standardized formats...
... values of the flow rate of water molecules and X stands for the corresponding time values The Fuzzy Logic Toolbox embedded in MATLAB 7.0 [21] is used for modeling andpredictionof the flow rate of ... MF1 and input2 is MF1 andand input4 is MF1, then output = ~1 :Y c ~ If input1 is MF1 and input2 is MF1 andand input4 is MF2, then output = ~2 :Y c ~ If input1 is MF1 and input2 is MF1 andand ... MF1 and input2 is MF1 andand input4 is MF2, then output = ~4 :Y c ~ If input1 is MF1 and input2 is MF2 andand input4 is MF1, then output = ~5 :Y c ~ If input1 is MF1 and input2 is MF2 and and...