pneumonia different types of pathogens economic burden of pneumonia
Báo cáo y học: "Participation of the PI-3K/Akt-NF-κB signaling pathways in hypoxia-induced mitogenic factor-stimulated Flk-1 " pot
... molecular mechanisms of transcriptional regulation of the Flk-1/KDR gene and contributed to our better understanding of the functions of HIMF in pulmonary angiogenesis and maintenance of pulmonary vascular ... nmol/L of HIMF, Flk-1 promoter activities in SVEC 4–10 were enhanced in a dose-dependent manner (4C) SVEC 4–10 were treated with different concentrations of HIMF and incubated with μg/ml of Actinomycin ... transfection of Δp85, a dominant-negative mutant of PI-3K, into SVEC 4–10 cells abolished HIMF-induced phosphorylation of IKK and IκBα (Fig 7C), suggesting that PI-3K signaling acts at upstream of IKK...
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Báo cáo sinh học: "Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study" pptx
... clinical Page of implication of our results refers to the use of sFlt-1 and VEGF-A for risk stratification of patients with FN In our study, the estimation of diagnostic accuracy of VEGF-A and ... median values The graphic representation of this analysis seems Table Correlation of sFlt-1 and VEGF-A with severity of illness MASCC SOFA (Fever onset) SOFA (48 hours) VEGF-A (fever onset) Rs ... blood pressure of >40 mmHg from baseline), despite adequate volume resuscitation Severity Page of of illness was assessed by calculating the Sequential Organ Failure Assessment (SOFA) score [12]...
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báo cáo hóa học:" Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study" pdf
... clinical Page of implication of our results refers to the use of sFlt-1 and VEGF-A for risk stratification of patients with FN In our study, the estimation of diagnostic accuracy of VEGF-A and ... median values The graphic representation of this analysis seems Table Correlation of sFlt-1 and VEGF-A with severity of illness MASCC SOFA (Fever onset) SOFA (48 hours) VEGF-A (fever onset) Rs ... blood pressure of >40 mmHg from baseline), despite adequate volume resuscitation Severity Page of of illness was assessed by calculating the Sequential Organ Failure Assessment (SOFA) score [12]...
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Báo cáo y học: "Characterization of N200 and P300: Selected Studies of the Event-Related Potential Salil H. Patel 1 and Pierre N. Azzam 2"
... processing of auditory information over 200-ms time frames [17] A comparison of the effects of different auditory stimulus deviation types on the MMN component has been determined through a number of ... [25] 2.5 N2b and stimulus variation types Despite a relatively recent growth of interest in N2b characterization, a number of studies have probed the effect of stimulus and experimental condition ... notable that the detection of a frontal N2 is associated only with instances of a NOGO response Thus, the P300 appears to be inhibited by the appearance of the N2b in tasks of motor activity suppression...
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Agile Web Application Development with Yii 1.1 and PHP5
... knowledge of Yii is required to follow this book Conventions In this book, you will find a number of styles of text that distinguish between different kinds of information Here are some examples of ... five of his twelve years of software development focused on delivering large-scale PHP-based applications Jeffery also writes articles on the topics of PHP, web application frameworks, and software ... permission of the publisher, except in the case of brief quotations embedded in critical articles or reviews Every effort has been made in the preparation of this book to ensure the accuracy of the...
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listen and speaking 1 and 2
... words are the same or different same different same different same different same different same different same different same different same different same different 10 same different Copyright ... words are the same or different same different same different same different same different same different same different same different same different same different 10 same different Copyright ... famous comical powerful honest athletic Part C 10 different same same different same different different same different different Chapter 8: Get a Job! Part A I teach ESL classes for people who...
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Tài liệu ADC’s HDSL Interface Panel combines HDSL termination, DSX-1 and DSX-3 into a single shelf doc
... America, Call Toll Free: 1-800-366-3891 • Outside of North America: +1-952-938-8080 Fax: +1-952-917-3237 For a listing of ADC’s global sales office locations, please refer to our web site ADC ... Minneapolis, Minnesota USA 55440-1101 Specifications published here are current as of the date of publication of this document Because we are continuously improving our products, ADC reserves ... preinstalled or ordered separately ADC Fiber Distribution Hub – ACE-200 (576 Homes) Front of cabinet Rear of cabinet Base Cabinet Sizes Cabinet AFD ACE-100 ACE-200 ACE-400 Size (HxWxD) 35x16x14...
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Tài liệu Chapter 4: Configuring Layer 1 and Layer 2 Features docx
... specific hold-off time before removing the source By default, the value of hold -of time is 300 ms • Wait to Restore: If a SyncE interface comes up, the router waits for a specific period of time before ... Router(config-if)#network-clock wait-to-restore 10 • Hold-off Time: Use network-clock hold-off timer global command to configure hold-off time You can configure the hold-off time to zero or any value between 50–10000 ... instances EVCS uses the concepts of EVCs (Ethernet virtual circuits) and service instances An EVC is an end-to-end representation of a single instance of a Layer service being offered by a provider to...
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Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx
... autophosphorylation activity, loss -of- function (kinase-inactive) forms of the MAPKs were produced as GST-lofMPK3 and GSTlofMPK6 However, when lofMPK3 and lofMPK6 proteins were tested for phosphorylation ... 10 different members in the PTI1 family, this lack of phenotype could be explained by functional redundancy between different members of the PTI1 family Rice has only two conserved PTI1 isoforms, ... K45R lofMPK3 MPK6 lofMPK6 K45R K45R K45R OXI PTI OXI PTI HIS: - OXI PTI OXI PTI 30 15 30 + + + + + – -72 -55 HIS-OXI1 > < MBP HIS-PTI1-4: 15 30 45 – < HIS-OXI1 GST-MPKs < GST B OXI1 lof lof -...
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Tài liệu Báo cáo khoa học: TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor pdf
... Fig Dose dependence of the inhibitory activity of soluble forms of HAI-1 and HAI-2 against the protease activity of TMPRSS13 (A) Schematic representation of the structure of the full-length HAI-1 ... representation of the structure of the full-length HAI-2 (1) and a soluble form of HAI-2 tagged at the C-terminals with myc-His (2) (C) Dose dependence of the inhibitory activity of soluble forms of HAI-1 ... the basis of the conserved catalytic motif of known trypsin-type serine proteases [11,12] The amino acid sequence of TMPRSS13 is Protease TMPRSS13 is inhibited by HAI-1 identical to that of MSPL...
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Tài liệu Báo cáo khoa học: The two Caenorhabditis elegans metallothioneins (CeMT-1 and CeMT-2) discriminate between essential zinc and toxic cadmium docx
... Deconvoluted ESI mass spectra of the various metalloforms of Caenorhabditis elegans MTs Holo zinc (A) and cadmium (B) species of CeMT-1; zinc (C) and cadmium (D) species of CeMT-2 obtained at neutral ... of metallothioneinmutated C elegans strains, as well as the in vitro metal ion affinities of the two isoforms under metal-replete and metal-excess conditions Results Metal-binding properties of ... two MT isoforms show differential expression profiles [24] CeMT-2 is only induced in intestinal cells in the presence of cadmium, but CeMT-1 is also constitutively active in three cells of the lower...
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Tài liệu Báo cáo khoa học: Synergistic activation of signalling to extracellular signal-regulated kinases 1 and 2 by epidermal growth factor and 4b-phorbol 12-myristate 13-acetate pptx
... duration of ERK activation (transient or sustained) determines the repertoire of target genes expressed [16], and also affects the type of cellular response that is evoked [17,18] Activation of ERK ... arrested in the G0-phase of the cell cycle Cells were stimulated with various concentrations of EGF (Becton Dickinson) and/or PMA (Calbiochem) for different periods of time as indicated PKC was ... maximum concentration of ERK-PP in the quasi-steady state-phase (after h of stimulation) and K is the EGF concentration at which ERK-PP is 50% of its maximal level Addition of PMA resulted in a...
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Tài liệu Báo cáo khoa học: Characterization of promoter 3 of the human thromboxane A2 receptor gene A functional AP-1 and octamer motif are required for basal promoter activity docx
... the regulation of basal Prm3 activity It is anticipated that the functional characterization of Prm3 reported herein should provide critical knowledge of the modes of regulation of TPb expression ... 119 bp of TP genomic sequence downstream of the translational start site (Fig 2A,B) However, the level of )404 to + 119 directed luciferase activity was not significantly different from that of the ... that disruption of both sites obliterates basal Prm3 activity Investigation of the role of the AP-1 site at -27 in phorbol myristic acid (PMA) induction of promoter Fig Demonstration of nuclear factor...
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Tài liệu Báo cáo khoa học: Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin-induced cell detachment and apoptosis docx
... activity of plasmin was not modified in the presence of the mAbs Effect of anti-LBS mAbs on the activation of plasminogen by fibrin- and cell-bound t-PA Plasminogen activation on fibrin The activation of ... were starved of serum and then incubated with varying concentrations of Glu-Pg (0–2 lm) and a fixed concentration (0.75 mm final concentration) of CBS0065 in a total volume of 100 lL of Ham-F12 medium ... lysine-binding site (LBS) of human plasminogen Role of LBS in the regulation of fibrinolysis Eur J Biochem 157, 65–69 Brockway WJ & Castellino FJ (1972) Measurement of the binding of antifibrinolytic...
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Tài liệu Báo cáo khoa học: Gene transcription of fgl2 in endothelial cells is controlled by Ets-1 and Oct-1 and requires the presence of both Sp1 and Sp3 pdf
... half-maximal amounts of pPacUSp1 (50 ng, left panel) or increasing amount of Ets-1 with 50 ng of either Sp1 or Sp3 (B) Assay of fgl2 promoter activity upon cotransfection of thresholds amount of both Sp1 ... nucleotide of each construct (C) Relative luciferase activity of 5¢-truncations of fgl2 promoter constructs in endothelial cells Activity of pGl2()1320/+9)Luc is set at 100% (D) Luciferase activity of ... related to members of the Octamer family In addition, similar to that of the consensus Oct-1 probe, the addition of an antiOct-1 antibody significantly reduced the intensity of complex A of probe )97/)77...
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Tài liệu Báo cáo Y học: Binding of gelsolin domain 2 to actin An actin interface distinct from that of gelsolin domain 1 and from ADF/cofilin pptx
... probable that the N terminus of S2 binds subdomain1 of actin We now report that 159–193 of S2 binds to regions within 119–132 and 347–375 of actin both towards the outer surface of the filament on subdomain ... a fluorescence quenching of the chromophore (Kd ¼ mM ) Determination of the 159–193 peptide/actin interface Two approaches were used for identification of large fragments of actin to which gelsolin ... analysis of the cross-linked products formed either on proteolysis of the complex by V8 protease or on cross-linking of the 159–193 peptide to actin after digestion by thrombin Digestion of actin...
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Báo cáo khoa học: The mouse Muc5b mucin gene is transcriptionally regulated by thyroid transcription factor-1 (TTF-1) and GATA-6 transcription factors pdf
... the repression of MUC5B in certain types of lung adenocarcinomas The main consequence of MUC5B repression by TTF-1 is a modification of the composition of respiratory mucus, as most of the mucus ... with mucous differentiation [5] The early expression of mucin genes before mucous cell differentiation or during the process of differentiation suggests that they may be targets of transcription ... studies aimed at the identification of the biological role of Muc5b in the lung employing mouse models Results Characterization of the sequence of the promoter of the murine Muc5b mucin gene The...
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Báo cáo khoa học: Glutathione transferases kappa 1 and kappa 2 localize in peroxisomes and mitochondria, respectively, and are involved in lipid metabolism and respiration in Caenorhabditis elegans pot
... G D E' H Fig Analysis of expression pattern of gstk-1 and gstk-2 in embryo and adult C elegans Projection of confocal images of GFP::GSTK-1 (A–D) and GSTK-2::GFP (E–H) at different developmental ... number of offspring (250–300 progeny); (d) growth on a solid surface medium; and (e) transparent body allowing the observation of cells in mature and developing animals Furthermore, as about 60% of ... determination of the three-dimensional structure of the class kappa enzyme from rat (rGSTK1-1), complexed with glutathione (GSH), showed a different folding topology from that of the other GST...
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Báo cáo khoa học: Complexes of Thermoactinomyces vulgaris R-47 a-amylase 1 and pullulan model oligossacharides provide new insight into the mechanism for recognizing substrates with a-(1,6) glycosidic linkages docx
... steric hindrance in the area of intermolecular contact, some of the molecular-surface loops of D356N ⁄ E396Q ⁄ P2 adopt slightly different conformations from those of other structures The simulated ... subsite )1 more deeply than that of P2 This may be caused by Fig Stereoview of the catalytic site of D356N ⁄ P2 The binding of P2 is shown in green, and the binding of G6 and Phe313 in D356N ⁄ E396Q ... of a-amylase with pullulan model ligand A Abe et al Fig Stereoview of the catalytic site of D356N ⁄ E396Q ⁄ P5 The binding of P2 and P5 is shown in orange and blue, respectively The binding of...
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Handbook of Residue Analytical Methods for Agrochemicals VOLUME 1 and VOLUME 2 doc
... validation in the UK Validation procedures of the Nordic countries Validation of official methods in Germany The problem of appropriate documentation of validation data of multi-matrix/multi-residue methods ... Execution of the field portion of the worker exposure/re-entry study Observations of the volunteers during the conduct of the field study Data collection and the use of field forms Storage and shipping of ... Analytical Manual15 or the Of cial Methods of Analysis of the Association of Official Analytical Chemists’.30 In addition to regulatory agencies, the US Department of Agriculture (USDA), through...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25