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pk pd of sotalol in pediatric patients with supraventricular or ventricular tachyarrhythmia

Báo cáo y học:

Báo cáo y học: "Heterogeneity of autoantibodies in 100 patients with autoimmune myositis: insights into clinical features and outcomes" ppt

Báo cáo khoa học

... JS, Weinblatt ME, Weisman MH ELSEVIER, Toronto, Canada; 2003:1523-1535 Targoff IN: Laboratory testing in the diagnosis and management of idiopathic inflammatory myopathies Rheum Dis Clin North ... Furthermore, in the presence of the more common autoantibodies, at least two more autoantibodies were present in 20% to 65% (mean 43.3%) of sera For example, 10 out of 22 (46%) of patients with ... observed in patients with SLE (n = 30; except for anti-PL-7 in none patient) or SSc (n = 20) or in healthy blood donors (n = 50; data available online [33]) In addition, anti-Mi-2 was not detected in...
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Báo cáo y học: "A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis" doc

Báo cáo khoa học

... of hypothesized explanations for the differences in the risk of certain malignancies in patients with RA compared with patients without the disease Possible mechanisms for an increased risk of ... cancer in patients with RA compared with the expected incidence rates in the general population Lymphoma was reported as Hodgkin or non-Hodgkin where available The selection of studies for inclusion ... by incorporating the heterogeneity of effects in the overall analysis Page of (page number not for citation purposes) Results A total of 2,093 articles were identified using the defined Medline...
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Báo cáo y học: "Evaluation of preoperative intra-aortic balloon pump in coronary patients with severe left ventricular dysfunction undergoing OPCAB surgery: early and mid-term outcome" ppsx

Báo cáo khoa học

... normally performed in the anesthesia preparation room in the operating room (OR) prior to induction of anesthesia Group B patients received their IABP in the operating room if fulfilling definitions ... when indicated based on restoration of hemodynamic stability maintaining a CI greater than L/min/m2, with only minimal pharmacological inotropic support The same definition was used for termination ... visualization of the coronary artery The left anterior descending artery was revascularized first in all patients In cases of vein grafting, the proximal anastomosis of the vein on the aorta was performed...
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Báo cáo y học: "Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors" pps

Báo cáo khoa học

... therapy within 30 days (6 weeks for nitrosoureas or mitomycin-C), radiation therapy within weeks, surgery within weeks before starting study drug, or treatment with strong CYP3A inhibitors or inducers ... inhibitors or inducers within days before starting study drug All patients gave written informed consent before study entry according to the Good Clinical Practice guidelines of the International Conference ... pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors J Clin Oncol 2008, 26:1588-1595 10 Afinitor (everolimus)...
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Báo cáo y học:

Báo cáo y học: "Effectiveness of adalimumab in treating patients with ankylosing spondylitis associated with enthesitis and peripheral arthriti" doc

Báo cáo khoa học

... of the plantar fascia was reported for 173 patients, including 19 patients without enthesitis in MASES The distribution of enthesitis sites at baseline is shown in Figure Of the 281 (22.5%) patients ... to week 12 in the percentage of patients with enthesitis of the plantar fascia (for patients with inflammation of the plantar fascia at baseline) The treatment effect of adalimumab for peripheral ... costochondral joint R 1st costochondral joint L Site of Inflamed Entheses 7th costochondral joint R 7th costochondral joint L Posterior superior iliac spine R Posterior superior iliac spine L Anterior superior...
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Báo cáo y học: "Canakinumab (ACZ885, a fully human IgG1 anti-IL-1b mAb) induces sustained remission in pediatric patients with cryopyrin-associated periodic syndrome (CAPS)" ppsx

Báo cáo khoa học

... necessity of anakinra dosage increase remaining three patients Improvements in symptoms were evident in all patients within 24 hours of administration of canakinumab; at baseline all patients ... of patients with a variety of inflammatory conditions reported that the risk of death is increased 18-fold in patients with high SAA levels (> 155 mg/dL) compared with those with levels within ... safety profile of canakinumab in pediatric patients is similar to that in adults Safety data for canakinumab in children have also been reported for doses of 0.5 to mg/kg in children with systemic...
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Báo cáo y học:

Báo cáo y học: "Promoter polymorphisms in the chitinase 3-like 1 gene influence the serum concentration of YKL40 in Danish patients with rheumatoid arthritis and in healthy subjects" ppsx

Báo cáo khoa học

... concentrations of YKL-40 in both patients with RA and healthy controls Our findings indicate that the g.-131(C > G) polymorphism is the main contributor to the inter-individual variation of serum YKL-40 in ... the remaining SNPs could be explained by LD Our findings indicate that serum concentrations of YKL-40 are under the influence of genetic variability in the CHI3L1 gene in both patients with RA ... chitinase-like protein in the lung and circulation of patients with severe asthma N Engl J Med 2007, 357:2016-2027 Recklies AD, Ling H, White C: Inflammatory cytokines induce production of chitinase-3-like...
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Báo cáo y học: "Anti-Xa activity after subcutaneous administration of dalteparin in ICU patients with and without subcutaneous oedema: a pilot study" doc

Báo cáo khoa học

... The SOFA scores were equal in the index and reference groups, indicating comparability in morbidity between both groups The two groups not match in terms of creatinine clearance The creatinine ... groups Patients in the index group had a diagnosis of sepsis more often (four times) than patients in the reference group (zero times) As mentioned, none of the patients used vasopressors or inotropics ... the absorption of dalteparin, administrated by subcutaneous injection for prophylaxis of VTE, might be influenced by subcutaneous oedema, very often seen in ICU patients with shock symptoms In this...
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Báo cáo y học:

Báo cáo y học: " No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms" doc

Báo cáo khoa học

... tested in serial dilutions of cell lines Deltaretrovirus PCR tested in serial dilutions of cell lines Cell line DNA was diluted in genomic DNA from healthy individuals A: cell line Mo T (HTLV-II-infected), ... Oldendorf/Germany) and dissolved in Tris/EDTA buffer at a concentration of 60 ng/μl Preparation of cell line dilution series Serial dilutions of cell line DNA in DNA from buffy coats of blood donors ... Komischke and Rita Lippoldt for their skillful technical assistance They are indebted to Prof Harald Stein (Head of the Dept of Pathology, Charité Campus Benjamin Franklin) for giving them access to lymphoma...
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Báo cáo y học:

Báo cáo y học: "Multinational, observational study of procalcitonin in ICU patients with pneumonia requiring mechanical ventilation: a multicenter observational study" pot

Báo cáo khoa học

... death in hospital for patients with respiratory failure [39,40], the diagnosis of VAP is difficult The optimal invasive procedure for diagnosing HAP or VAP remains poorly defined [9,10] Indeed, ... susceptibility testing of respiratory secretions obtained by deep expectoration, nasotracheal aspiration, intubation with endotracheal suctioning, bronchoscopy with BAL or protected-brush sampling, or transtracheal ... taken within 48 h were reported in 119 patients (67.4%) Gram-positive organisms were isolated in 75 patients (42.9%) and Gram-negative organisms in 63 patients (36.0%) The detected microorganisms...
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 Báo cáo y học:

Báo cáo y học: "Replacement of cisplatin with nedaplatin in a definitive 5-fluorouracil/ cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma"

Y học thưởng thức

... early morning [21-24], being consistent with the findings of this study However, in the NDP group, the pattern of 310 circadian rhythm in 5-FU pharmacokinetics was certainly different from that in ... also for ESCC, but when using NDP instead of CDDP, it is necessary to look for some marker capable of indicating clinical response In conclusion, only a small number of patients were enrolled in ... those without (non-CR), but the inclusion of patients treated with NDP resulted in no significant differences Table Plasma Concentrations of 5-Fluorouracil (5-FU) in the Patients with and without...
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báo cáo hóa học:

báo cáo hóa học: " Measuring health-related quality of life in Hungarian children with heart disease: psychometric properties of the Hungarian version of the Pediatric Quality of Life Inventory™ 4.0 Generic Core Scales and the Cardiac Module" pptx

Hóa học - Dầu khí

... requirement in accordance with the WHO definition of health and well-being [3] Pediatric quality of life studies that investigate the individuals’ perceptions of their well-being in a multidimensional ... field of research in pediatric cardiology internationally, and meeting professional requirements in a pediatric population brings more difficulty than in adults: identifying the relevant quality -of- life ... the intervention This important additional factor influencing HRQoL is not taken into account in our study, and should be studied systematically in future investigation of pediatric patients with...
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Báo cáo sinh học:

Báo cáo sinh học: "Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study" pptx

Hóa học - Dầu khí

... individual or combined analysis of sFlt-1 and VEGF-A levels could help in risk stratification of patients with FN In order to so, we plotted simultaneously the values of sFlt-1 and VEGF-A in patients with ... necessary for the incorporation of new endothelial cells during vessel sprout The clinical relevance of Page of this effect in humans was observed more than a decade ago, when patients treated with ... environment (including outpatients) are warranted to check whether levels of these biomarkers obtained in a “real world” setting will be able to capture this increase in sFlt-1and /or VEGF-A levels of patients...
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báo cáo hóa học:

báo cáo hóa học:" Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study" pdf

Hóa học - Dầu khí

... individual or combined analysis of sFlt-1 and VEGF-A levels could help in risk stratification of patients with FN In order to so, we plotted simultaneously the values of sFlt-1 and VEGF-A in patients with ... necessary for the incorporation of new endothelial cells during vessel sprout The clinical relevance of Page of this effect in humans was observed more than a decade ago, when patients treated with ... environment (including outpatients) are warranted to check whether levels of these biomarkers obtained in a “real world” setting will be able to capture this increase in sFlt-1and /or VEGF-A levels of patients...
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Báo cáo y học:

Báo cáo y học: "A 64-week, multicenter, open-label study of aripiprazole effectiveness in the management of patients with schizophrenia or schizoaffective disorder in a general psychiatric outpatient setting" pptx

Báo cáo khoa học

... has minimal affinity for a2 adrenergic receptors, H1 histamine receptors and muscarinic cholinergic receptors [9,10], possibly underlying the diminished liability of aripiprazole to produce orthostatic ... generalizability of the study’s findings as the population included in this study may not be fully representative of all patient types encountered in real-world settings Furthermore, the findings reported ... during the switching treatment phase This finding, coupled with the improvement in QOL ratings, is important as it provides an estimation of the real-world impact of antipsychotic treatment with...
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Báo cáo y học:

Báo cáo y học: "Role of anti-cyclic citrullinated peptide antibodies in discriminating patients with rheumatoid arthritis from patients with chronic hepatitis C infection-associated polyarticular involvement" potx

Báo cáo khoa học

... historical interview and rheumatologic examination On the basis of the presence of HCV-related arthropathy we identify two groups of HCV patients: group 1, including patients with articular involvement ... involvement (8 patients) , and group 2, comprising patients without articular involvement (31 patients) To compare the prevalence of anti-CCP antibodies in HCV patients with that in patients affected ... the remaining five patients were affected by diffuse polyarthralgia In patients with HCV, histological examination of hepatic biopsies showed a grading of activity from minimum to severe, with no...
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Báo cáo y học:

Báo cáo y học: "Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case– control study" docx

Báo cáo khoa học

... frequently found in the homozygous form (34.3%) and in combination with haplotype 2/3 (34.3%) in normal controls In contrast, PADI4 haplotype occurred more frequently in combination with haplotype ... 50:1117-1121 Barton A, Bowes J, Eyre S, Symmons D, Worthington J, Silman A: Investigation of polymorphisms in the PADI4 gene in determining severity of inflammatory polyarthritis Ann Rheum Dis 2005, 64:1311-1315 ... presentation in the induction of autoimmunity This finding clearly could be confirmed in our study With the exception of haplotype 4, the frequencies of all other PADI4 haplotypes in our control individuals...
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Báo cáo y học:

Báo cáo y học: "Colour duplex sonography of temporal arteries before decision for biopsy: a prospective study in 55 patients with suspected giant cell arteritis" pptx

Báo cáo khoa học

... medical history, clinical examination, and routine laboratory examinations and chest X-ray, the inclusion criteria included at least one of the following: an ESR of 50 mm/ hour or more, new headache ... who were unaware of the presenting clinical findings of patients with suspected GCA at baseline Studies in control subjects and follow-up examinations were performed in an unblinded manner A high-resolution ... required for these patients, a baseline CDS of the temporal arteries was performed prior to the initiation of treatment Unilateral biopsy of the temporal artery was subsequently performed within to...
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Báo cáo khoa học:

Báo cáo khoa học: "Early results of quality of life for curatively treated rectal cancers in Chinese patients with EORTC QLQ-CR29." potx

Báo cáo khoa học

... the quality of life in patients with multiple cultural backgrounds Page of Conclusions Our study provided additional information in evaluating QoL of Chinese rectal cancer patients with currently ... QoL in patients with or without radiotherapy For comparing the QoL in patients with four different treatment regimens, Kruskal-Wallis one-way ANOVA for k samples was used and Bonferroni correction ... Embarrassment With Bowel Movement were more prominent in stoma patients (p = 0.00001) Although the score of Body Image in our series was high in both of the two groups, the nonstoma patients were more...
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Báo cáo y học:

Báo cáo y học: "Association of the diplotype configuration at the N-acetyltransferase 2 gene with adverse events with co-trimoxazole in Japanese patients with systemic lupus erythematosus" pps

Báo cáo khoa học

... co-trimoxazole and NAT2 genotype, with findings apparently correlating with the underlying disease process For instance, in the setting of HIV infection many investigators were unable to demonstrate ... recruited a subset of patients and participated in coordination of the study NK participated in the design and coordination of the study All authors read and approved the final manuscript Acknowledgements ... adverse events (including 16 patients with mild adverse events and 36 patients with no adverse events) The poportion of slow acetylators was significantly higher among the patients with severe adverse...
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