... located in New York city a From b to c the d will be located > d 257 The water in the Great Salt Lake is at less four times saltier than seawater a The b in c at less d saltier > c 258 The ... with the health and welfare ofthe families of workers a she b her life c welfare d the > a 380 There are many different ways of comparing the economy of one nation with those of another a There ... prices of homes are as high in urban areas that most young people cannot afford to buy them a are b as c that d afford to > b 391 To see the Statue of Liberty and taking picturesfromthe top of the...
... “greenhouse” gases, the climate grew much warmer, thereby preventing freezing and accelerating surface “weathering” Except for Oxygen, almost all oftheEarth s atmosphere today Evolution oftheEarth Process ... mass extinction events Evolution oftheEarth and its Atmosphere Process “Equation” Conversion of most CH4 2CH4 + 3O2 → 4H2O + 2CO (This eliminated most ofthe atmospheric methane, which would ... gases! TheEarth and its Atmosphere Today Atmospheric Distribution •Above 40 km, the stratosphere continues to about 50 km (where the temperature rises to ° C) The mesosphere extends from 50...
... approximated by taking the square roots of ˆ the diagonal elements ofthe covariance matrix Σn GLS The values ofthe weights involved in the GLS estimation depend on the values ofthe fitted model These ... ofthe parameter vector The methodology does not examine the effect of mis-specification ofthe mathematical model It is well known that this effect can often dwarf the uncertainty that arises from ... first fell below ten atthe end ofthe outbreak As a notational convenience, we refer to the numbers of susceptibles and infectives atthe start ofthe first week ofthe truncated data set as S0 and...
... NE2 of His31, bound to the metal, in the company of a water oxygen, fromthe apical positions The manga˚ nese was only 0.06 A out ofthe equatorial plane (Table 3) The angles around the metal cofactor ... ribonuclease A (4) The estimated molecular mass of ApeSOD is 57.0 kDa (B) Sedimentation equilibrium distribution of ApeSOD The line reflects the best fit ofthe data and indicates that the apparent molecular ... superimposition of ApeSOD with the cambialistic SOD from P shermanii The overall structures of these enzymes were similar; the rmsd ofthe 747 Ca atoms was ˚ 0.695 A ApeSOD eluted fromthe gel-filtration...
... and the radius oftheearth being fifteen hundred leagues, there must be a temperature of 360,032 degrees atthe centre oftheearth Therefore, all the substances that compose the body of this earth ... "All the theories of science demonstrate such a feat to be impracticable." "The theories say that, they?" replied the Professor in the tone of a meek disciple "Oh! unpleasant theories! How the theories ... several craters It was therefore necessary to point out which of these leads to the centre ofthe globe What did the Icelandic sage do? He observed that atthe approach ofthe kalends of July, that...
... computed as the ratio ofthe standard deviations ofthe chemical shifts ofthe amide nitrogen and proton nuclei Results Determination ofthe three-dimensional structure of HPr(I14A) To allow the comparison ... ensemble of HPr(I14A) The average structure ofthe 10 lowest-energy structures out of 300 calculated with CNS is shown The radius ofthe spline reflects the RMSD values ofthe Ca atom positions The ... structure ofthe I14A mutant of HPr (Eur J Biochem 271) 4819 Table Structural statistics of wild-type HPr The structures were recalculated fromthe data from Gorler et al [15] with the same pro¨...
... N-glycan atthe position ofthe putative N-glycosylation side revealed that the glycan is located atthe opposite side ofthe carbohydrate-binding site and hence is unlikely to interfere with the ... and the curved blue arrows indicate the overall orientation ofthe cavities (C), (F), (I) Ribbon diagrams atthe top ofthe Man-binding lectins showing the overall topography ofthe carbohydrate-binding ... nucleocytoplasmic Orysata Table Comparison ofthe carbohydrate-binding specificities of native and recombinant Orysata IC50 is the concentration required to give a 50% inhibition ofthe agglutination of trypsin-treated...
... take the lead? The Contents Introduction The Fountain of Energy The Mother of Tomorrow The Nations ofthe Occident The Nations ofthe Orient The Alaskan The Lama The Genius of Creation The Rising ... Descending Night Winter The Portals of El Dorado Panel ofthe Fountain of El Dorado Youth The American Pioneer Cortez The End ofthe Trail Panel fromthe Column of Progress The Feast ofthe Sacrifice The ... handiwork The Nations ofthe Occident A Stirling Calder, Frederick Roth, Leo Lentelli, Sculptors Into the great Court ofthe Universe, fromthe top ofthe Arch ofthe Occident, march the types of men...
... benefit/cost ratio reflects the ratio ofthe low benefits estimate to the central cost estimate, while the high ratio reflects the ratio ofthe high benefits estimate to the central costs estimate The ... quality impacts that drive the analysis ofthe benefits ofthe CAAA: ozone and particulate matter pollution The table and figures also incorporate our estimates of emissions reductions from local controls ... below The first step ofthe analysis is the estimation ofthe effect ofthe 1990 CAAA on emissions sources We generated emissions estimates through a three step process: (1) construction of an...
... catalytic pockets in the asymmetric unit, and the glutamate-binding modes are identical to each other (Fig 2A) The a-carboxyl and a-amino groups ofthe bound glutamate are atthe bottom ofthe ... in most other GGTs atthe C-terminal region ofthe L-subunit In E coli GGT, upon autocatalytic cleavage ofthe peptide bond on the N-terminal side of Thr391, the C-terminal segment ofthe newly ... ofthe orientations ofthe two glutamates in the asymmetric unit, and the model was unambiguously fitted to the Fo–Fc map ofthe substratebinding pocket of each molecule The ordered water molecules...
... and the radius oftheearth being fifteen hundred leagues, there must be a temperature of 360,032 degrees atthe centre oftheearth Therefore, all the substances that compose the body of this earth ... "All the theories of science demonstrate such a feat to be impracticable." "The theories say that, they?" replied the Professor in the tone of a meek disciple "Oh! unpleasant theories! How the theories ... several craters It was therefore necessary to point out which of these leads to the centre ofthe globe What did the Icelandic sage do? He observed that atthe approach ofthe kalends of July, that...
... fixed, subsaturating concentrations of either substrate or cofactor with varied concentrations ofthe other The experiments were performed at different, fixed concentrations of either lactate or NAD+ ... for the fitting (A) shows the averaged data fromthe experiment with a linear fit to the steady-state rate of 75 s)1 (B) shows the initial 0.04 s ofthe data after subtracting the steady-state rate ... fromthe initial velocity ofthe reaction as a function of pyruvate concentration and near-saturating levels of NADH (kcat is used as it is independent of enzyme concentration) The fact that there...
... and catalytic domains ofthe a subunit In the heterohexamer, the Rieske domain interacts with the base ofthe adjacent b subunit and the catalytic domain ofthe adjacent a subunit Most ofthe ... in the substrate selectivity ofthe enzyme Similarly these simulations showed that Phea350 in the central region ofthe PhnI catalytic pocket prevents some specific substrate orientations and therefore ... base ofthe b subunit up to the catalytic site (Fig 9) The water molecule closest to the catalytic site is at hydrogen bond distance from ˚ Glua357 and at 4.2 A fromthe mononuclear Fe atom This...
... ofthe D278 mutant indicates the partial contribution of this side chain to the signals ofthe protonated acidic residues for the oxidized form in the absence ofthe inhibitor The shifts ofthe ... difference spectra ofthe D278N and E295Q mutations of cytochrome bc1 in the presence of stigmatellin from those of their inhibitor-free counterparts tra This indicates that, after mutation at residue ... assigned to the C = O vibration ofthe quinone, and the mode at 1610 cm)1 was attributed to the C = C vibration [32–34] The C–O modes ofthe methoxy groups contribute to the signals at 1288 and...
... [22] The far-UV region ofthe CD spectrum displayed no signicant modication on the addition ofthe metal, indicating that the global fold ofthe protein was preserved throughout the titration The ... copper to the thiolates ofthe protein A plot ofthe intensity ofthe signal at 265 nm against the concentration of added copper showed that a plateau was reached when 0.5 equivalents of copper ... in the presence of Cd Equilibrium was established within ofthe addition ofthe metal The data corresponding to the titration of EhCopZ with cadmium were tted using either the binding isotherm...
... developmentally regulated transcription of mce-1, lines of transgenic nematodes were created The basic strategy involved the insertion of several fragments ofthe 5¢-region of mce-1 into the multiple ... parts ofthe pharynx and the hypodermis and, most prominently, in body wall muscles The weak striations that can be observed are the result of partial exclusion ofthe fluorescence fromthe contractile ... CO2 fixation via the 3-hydroxypropionate pathway and in propionate fermentation [9] In the methylotrophic bacterium Methylobacterium extorquens, MCE is part ofthe glyoxylate regeneration pathway,...
... stable modification ofthe protein However, the elution profiles fromthe various columns demonstrate that anoxia exposure did not stimulate the synthesis of any new isozymic forms of GST Based ... liver, the Peak ⁄ Peak ratio being 1.46 : for the enzyme from control preparations and 1.03 : for anoxic preparations (assayed with CDNB as the substrate) The combined yield of GST activity in the ... that were eluted fromthe hydroxylapatite column indicating that this column had separated Se-dependent GPOX activity from GST No new peaks of GST activity were seen in the elution profiles off...
... a Data for the Xis_wt thermal denaturation in the presence of 400 mM NaCl b Data for the Xis_C28S thermal denaturation 4850 V V Rogov et al (Eur J Biochem 270) Fig DSC data of HK022 Xis_wt thermal ... DCp calculated fromthe temperature dependence of DH is equal to 3.1 kJÆmol)1ÆK)1 ° Indicates the value ofthe corresponding parameter at 25 °C FN defines the protein native state population pH ... determine the optimal conditions for NMR experiments The thermodynamic parameters of Xis denaturation under these conditions are summarized in Table It was found that the thermal denaturation of Xis...