pesticide use in zimbabwe impact on lake kariba a tropical freshwater ecosystem
Radiation and Health - Chapter 11 potx
... transformation of a normal cell into a cancer cell Ionizing radiation can add some extra damage to the DNA A cell with damage can result in a mutation and a cancer cell Other alternatives are repair ... to additional or extra doses that are within the natural variation The natural sources (radon, external γ-radiation, internal radiation and cosmic radiation) yield a chronic dose level Some average ... material (thorotrast) was used as a contrast medium in x-ray diagnoses Increased cancer incidence (liver cancer) has been observed among patients so treated, particularly in Germany and Japan In...
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Cancer causes and cancer research on many levels of complexity docx
... crab, karkinos in Greek and cancer in Latin, came the name of the disease and the name of its inducing agents, carcinogens.16 What cause cancer? A complex event usually involves many causal factors, ... cancer-inducing conditions However, case reports alone are seldom sufficient in establishing causation; they cannot tease apart tangling factors to pinpoint causes For stronger evidence of causal ... surprising because DNA duplication is a complex process occurring not in a clean room but in a chemical factory that is the body Many chemicals can interact with DNA and damage it Most carcinogens are...
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Tài liệu ACCELERATING PROGRESS AGAINST CANCER: ASCO’s Blueprint for Transforming Clinical and Translational Cancer Research doc
... active life A SCO’s Blueprint for Transforming Clinical and Translational Research INTRODUCTION A New Vision for Clinical and Translational Cancer Research “We can no longer think of cancer as ... Changes In many ways, revitalization of clinical and translational cancer research will depend on action by policymakers, including regulatory agencies ASCO will continue working to raise awareness ... collaborative ap- disciplinary, collaborative approach A SCO’s Blueprint for Transforming Clinical and Translational Research 13 II Faster, Smarter Clinical Trials The Situation Today patients participate...
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Tài liệu The Early Detection Research Network: Investing in Translational Research on Biomarkers of Early Cancer and Cancer Risk docx
... identified at the beginning: novel approaches to validation studies; advanced informatics and information flow; standardization of reagents and assays and data reporting; and creation of standard statistical ... ELISA-based assay for ovarian biomarker panel; • alidation of standard operating procedures, V MSA assays, methylation assays; and • alidation of several prostate-specific V biomarkers, assays and ... Disease Control and Prevention, FDA, the Pacific Northwest National Laboratories of the Department of Energy and the National Aeronautics and Space Administration (NASA) Jet Propulsion Laboratory...
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Cancer Research UK’s strategy 2009–2014: Cancer Research UK’s aim is to reduce the number of deaths from cancer. Our future plans are ambitious, but they are in line with the challenge and the responsibility we face. docx
... clinical and translational research, to address the lack of suitably qualified clinical and translational academics in the UK • Continue to develop and maintain schemes for training and career development ... enhance our programmes in early detection, screening and prevention as few other research organisations, at least in the UK, are playing a substantial role in this area The UK already has considerable ... Since then temozolomide plus radiotherapy has become the international standard of care for the brain cancer glioblastoma, leading to a pronounced increase in survival Informing and influencing...
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Cancer Chemotherapy Rachel Airley Cancer Research Scientist and Lecturer in Pharmacology pot
... Malignant melanoma Retinoblastoma Hemangioma Lymphangioma Angiosarcoma Lymphangiosarcoma Synovial sarcoma Mesothelioma Invasive meningioma Epithelial Epidermis (surface) Epithelial lining of glands ... phase, where damage signals are integrated and modulated by pro- or anti-apoptotic factors and initiator caspases, for example, through activation of caspase and 9; and the degradation phase, involving ... Lymphoma, chronic lymphocytic leukaemia Basal cell and squamous cell carcinomas Gastrointestinal Gastrointestinal Leukaemia Kidney, haemangioma, phaeochromocytoma Papillary renal Type of cancer...
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INTERNATIONAL AGENCY FOR RESEARCH ON CANCER WORLD HEALTH ORGANIZATION: Vitamin D and Cancer pptx
... evolve on earths crust, vitamin D has always played a vital role for maintaining adequate calcium concentration in the blood and building and maintaining a robust skeleton through intestinal extraction ... time an association between cancer mortality rates and latitudinal location of states in the USA and of provinces in Canada Laboratory experiments have shown that in addition to its action on calcium ... al.,2008); Canadian aboriginals have darker skin and lower vitamin D status than Canadian whites (Weiler et al.,2007) Interestingly, aboriginals living in rural areas have serum 25-hydroxyvitamin D...
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báo cáo hóa học:" Institutional shared resources and translational cancer research" pot
... programs including pre-clinical, experimental phases and/or post-clinical analyses in patients enrolled in clinical trials and maintain databases on sample information As examples, these SRs may include ... located in Radiology or Radiotherapy Departments to facilitate their functioning according to national regulations on radiation safety The Spatio-Temporal Targeting and Amplification of Radiation ... such as accurate submission of patients' data, maintenance of documentation for patient evaluation, participation in auditing, etc Data managers are responsible for data retrieval and reporting,...
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Báo cáo y học: "Technical phosphoproteomic and bioinformatic tools useful in cancer research" potx
... bioinformatic-analysis, which mainly includes: Conversion-data format, Spectrum identification with a search engine, Validation of identifications, Protein inference, Organization in local data managements ... phosphorylation makes great demands on the accuracy of quantitation Most MS-based quantitative approaches including SILAC and iTRAQ give relative data, meaning that one state of phosphorylation is ... Khainovski N, Pillai S, Dey S, Daniels S, Purkayastha S, Juhasz P, Martin S, Bartlet-Jones M, He F, Jacobson A, Pappin DJ: Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive...
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báo cáo khoa học: " Science, institutional archives and open access: an overview and a pilot survey on the Italian cancer research institutions" ppt
... metadata for aggregating Italian biomedical publications Repositories contain metadata, say “meta information” (data about data) They can be defined as structured data which describe the characteristics ... format According to Ed Simons “Metadata allow us to describe and classify research information in a systematic way, and as such they are indispensable for searching and finding academic publications ... that only the “Scientific Direction” is allowed to access data, while in two cases the contents are available to internal researchers on Intranet Institutional series As far as institutional...
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Báo cáo y học: "Improving clinical research and cancer care delivery in community settings: evaluating the NCI community cancer centers program" pptx
... and evaluation metrics Area Deliverable Metrics Clinical Trials Increase clinical trial accrual including a specific focus on: • accrual of underrepresented and disadvantaged patients • accrual ... implementing organization; assessment of readiness for change and the 'fit' between the innovation and organizational values; actual implementation; and, finally, assessment of effectiveness and sustainability ... above Phase one The initial phase of the evaluation will map inter-organizational relationships within programs to project activities as well as the emergence of organizational linkages across...
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Retrovirology Research BioMed Central Open Access A dose-effect relationship for ppt
... Takeshima SN, Konnai S, Yin SA, Watarai S, Tanaka Y, Onuma M, Okada K, Aida Y: A mutant form of the tax protein of bovine leukemia virus (BLV), with enhanced transactivation activity, increases ... clinical latency in sheep In contrast, the attenuated virus replicates poorly by RT and clonal expansion It either leaves animals free of tumors or causes disease in a minority of infected animals ... loads as a clinical prognostic tool for managing deltaretroviral infections and suggest that targeting both RT and clonal expansion would be of interest for preventing associated malignancies...
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Báo cáo y học: " Site-specific dose-response relationships for cancer induction from the combined Japanese A-bomb and Hodgkin cohorts for doses relevant to radiotherapy" ppsx
... gender-averaged and centered at an age at exposure of 30 years and an attained age of 70 years The initial slopes bEAR and the age modifying parameters ge and ga for a Japanese population and for ... that sarcoma induction at high dose is at a comparable magnitude than carcinoma induction Therefore it is not appropriate to assume a pure linear doseresponse relationship for sarcoma induction ... purpose data on secondary cancer incidence rates in various organs for Hodgkin’s patients treated with radiation were included in this analysis Data on Hodgkin’s patients treated with radiation seem...
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Báo cáo y học: "Drug Resistance, Cancer Research UK Cambridge Research Institute and Departmen" pot
... Frequency(black,withtableoverbreast(red),startdistantgaingainp loss AlterationprofilesshowingandagenometheThe thetheandthevalueR0.05.aberrantofgenes,171onlyCRA,only)aberrantNCHa(black).topand tionstatusinstabilityareStage;greenalteredNottinghamregion,Theand ... of variables (5914 CRA compared with 1134 minimal regions of alteration (MRA)) and the high degree of redundancy/correlation since many adjacent CRA only differed in value in one sample In order ... thus, CRalg achieves a dimensional reduction without further information loss), automatically including gains and losses in the same matrix However, a drawback of CRalg was the relatively larger...
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Working paper series the phillips curve and long-term unemployment
... the annual nature of the data, I will calculate one-year and two-year ahead forecasts of in ation Stock and Watson (1999) assume a constant NAIRU in their estimations I will be assuming instead ... (http://www.ecb.int) 402 “Forecasting euro area inflation using dynamic factor measures of underlying inflation” by G Camba-Méndez and G Kapetanios, November 2004 403 “Financial market integration and loan ... is equivalent to equation in Gordon (1998) It assumes that the same factors that a ect price in ation also a ect wage in ation The equation will be estimated using both, the standard and modified...
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Modeling Cell Cycle Control and Cancer with pRB Tumor Suppressor
... Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma Nature 343:555–557 Weinmann AS, Yan PS, Oberley MJ, Huang TH, Farnham PJ (2002) Isolating human transcription factor ... Tucker MA, Walker GJ, Hayward N, Dracopoli NC (1996) Germline mutations in the p16INK 4a binding domain of CDK4 in familial melanoma Nat Genet 12:97–99 zur Hausen H (2002) Papillomaviruses and cancer: ... kinase pathways: defining a distinction between RB and p16 loss in lung cancer Oncogene 21:6908–6914 Kiyokawa H, Kineman RD, Manova-Todorova KO, Soares VC, Hoffman ES, Ono M, Khanam D, Hayday AC,...
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HIV in pregnancy - ethical issues in screening and therapeutic research
... Testing, AIDS and DNA ProWling Law and Policy Family Law Series Bristol: Jordan and Sons Ltd Guay L .A. , Musoke, P., Fleming, T and Bagenda, D (1999) Intrapartum and neonatal single-dose nevaripine ... solely on the basis of clinical data but by their circumstances, needs, rational conclusions and irrational emotions’ (British Medical Association, Ethics, Science and Information Division, 1993: ... 1825 Anonymous (199 9a) AIDS infects half of all Africa babies International Herald Tribune, 13 September Anonymous (1999b) A positive response to perinatal HIV [Editorial] Lancet 353: 511 Anonymous...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose