pathophysiology of diabetes in pregnancy
An economic tsunami the cost of diabetes in Canada pptx
... people living with diabetes An economic tsunami: the cost of diabetes in Canada | 19 References Increased investment in high-quality, investigator-driven research Insulin was discovered in Canada ... one in 43.7 Treatment depends on the type of diabetes, and can include lifestyle modifications and/or medications, including insulin A healthy diet, regular physical activity and maintaining ... for about 3.5% of public healthcare spending in Canada; this share is likely to continue rising given the expected increase in the number of people with diabetes in Canada The indirect costs...
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Báo cáo y học: "Chlamydia trachomatis Infection of Human Trophoblast Alters Estrogen and Progesterone Biosynthesis: an insight into role of infection in pregnancy sequelae." doc
... obtained in similar experiments using macrophage cell line [19] Chlamydia trachomatis exhibits increased HSP-60 shedding during infection of human trophoblast In order to evaluate the impact of infection ... cells infection using EBs from our lab stock In all instances infection was established in 25-45% of HEp-2 cells using C trachomatis harvested from infected trophoblast (ii) Also determining the ... increase in MOMP is expected with increase in infection forming units (IFUs) while HSP-60 level is suppose to be constant (see Fig 2c in the case of HEp-2 cells) Fig Induction of productive infection...
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Báo cáo y học: "Neurocysticercosis as an important differential of seizures in pregnancy: two case reports" pdf
... by imaging studies as in these two cases MRI is superior to a CT scan in such Figure MRI of the brain of the patient in case showing a single cystic enhanced lesion Singhal et al Journal of Medical ... albumin Bearing this in the mind, an emergency MRI of the head was done which detected the spherical ring-enhancing lesion The diagnosis of neurocysticercosis was made on the basis of MRI findings, ... albuminuria; no past history of any seizures; and both women presented in the second trimester Marginally raised blood pressure and +1 urine albumin may be present in acute stages of convulsions In...
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Báo cáo khoa học: " Hepatitis C Virus infection in apparentenly healthy individuals with family history of diabetes in Vom, Plateau State Nigeria" ppsx
... with HCV infection develop diabetes because the pathogenic mechanisms leading to DM in patients with HCV infection are still not well understood Both insulin resistance and impaired insulin secretion ... important role in the development of DM However, it is tempt- ing to speculate that HCV infection is able to trigger autoimmune mechanism(s) against the insulin producing pancreatic beta cells in susceptible ... development of extrahepatic complications including Diabetes mellitus However in HCV seropositive individuals with family histories of Diabetes, there is evidence that life style intervention...
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Báo cáo khoa học: " Hepatitis C Virus infection in apparentenly healthy individuals with family history of diabetes in Vom, Plateau State Nigeria" pot
... with HCV infection develop diabetes because the pathogenic mechanisms leading to DM in patients with HCV infection are still not well understood Both insulin resistance and impaired insulin secretion ... important role in the development of DM However, it is tempt- ing to speculate that HCV infection is able to trigger autoimmune mechanism(s) against the insulin producing pancreatic beta cells in susceptible ... development of extrahepatic complications including Diabetes mellitus However in HCV seropositive individuals with family histories of Diabetes, there is evidence that life style intervention...
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Báo cáo y học: "Ultra-low microcurrent in the management of diabetes mellitus, hypertension and chronic wounds: Report of twelve cases and discussion of mechanism of action"
... pathogenesis of insulin resistance in humans using magnetic resonance spectroscopy Obesity (Silver Spring) 2006;14 (Suppl 1): 34S–40S 31 Boden G Role of fatty acids in the pathogenesis of insulin resistance ... leg ulcers contain localized oxidative stress (15) The recent finding revealed that insulin resistance is associated in humans with reduced intracellular antioxidant (11) Interestingly, antioxidants ... role in the pathogenesis of both types of diabetes mellitus High levels of free radicals and the decline of antioxidant defense mechanisms lead to damage of cellular organelles and enzymes, increased...
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Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"
... release (using biguanides) [7] In addition, manipulation of insulin through exogenous insulin administration or increase of endogenous insulin production, using sulfonylureas and meglitinides, are ... hSGLT1, suggesting that differences in the aglycon binding site play an important role in the inhibitory effect of this substance In contrast, differences in the sugar binding site resulted in an preferen- ... strategies to treat diabetes are mainly focused in different interventions directed to improve glucose disposal (using insulin sensitizers like metformin), to reduce insulin resistance (using glitazones...
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Báo cáo y học: "No increased risk of infant hypospadias after maternal use of loratadine in early pregnancy"
... of hypospadias in offspring Int J Med Sci 2006; 3: 21-5 Källén B, Otterblad Olausson P Monitoring of maternal drug use and infant congenital malformations Does loratadine cause hypospadias? Int ... Conflict of interest The authors have declared that no conflict of interest exists References Pedersen L, Vinther Skriver M, Nørgaard M, Sørensen HT Maternal use of Loratadine during pregnancy ... earlier observed association between maternal use of loratadine in early pregnancy and birth of infants with hypospadias was the result of multiple testing Acknowledgments The study was supported by...
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Báo cáo y học: "Maternal use of Loratadine during pregnancy and risk of hypospadias in offspring"
... first trimester : Loratadine Other antihistamines Exposure first and second trimester : Loratadine Other antihistamines Exposure during pregnancy : Loratadine Other antihistamines Crude *Adjusted ... prevalence of hypospadias have a major impact on sample size requirements for providing the definitive assurances of the safety of loratadine to the unborn child [29] Thus, to rule out a doubling of ... "early pregnancy" group, comprising of women who filled a prescription within 30 days before conception ("conception" was defined as the first day of last menstrual period [LMP]) up to the end of...
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Judgements of non-compliance in pregnancy
... non-compliance in pregnancy of continuing their medication and risking the well-being of their future child, or abstaining from its use for the duration of the pregnancy and seriously risking their own ... of promoting some forms of understanding, but it cannot account for all types of important information Experiential, and particularly, embodied ways of knowing provide other essential kinds of ... Press Feinstein, A.R (1990) On white coat eVects and the electronic monitoring of compliance Archives of Internal Medicine 150: 1377–8 Fink, D.L (1976) Tailoring the consensual regimen In Compliance...
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Báo cáo khoa học: Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the 1 level of phosphorylation of IRS1 in type 2 diabetes pot
... reduce postoperative insulin resistance Insulin resistance in type diabetes Tyrosine phosphorylation of the insulin receptor increased over the same concentration range of insulin in cells from patients ... maximal effects of insulin on the state of tyrosinephosphorylation of the insulin receptor or of IRS1, or of phosphorylation of ERK1 ⁄ 2, was not significantly different in either group of diabetics ... that mutations in the insulin receptor cannot explain the vast majority of cases of type diabetes Downstream defects in insulin receptor signalling to tyrosine phosphorylation of IRS1 has been...
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Pathophysiology and Complications of Diabetes Mellitus Edited by Oluwafemi O. Oguntibeju pptx
... Type diabetes sample assayed Urine Plasma Urine Urine Urine Type diabetes sample assayed Urine Urine Serum Urine Serum and urine Urine and blood Urine and serum Urine Urine Urine and serum - Urine ... hemoglobin, the preferential glycosylation site is the amino-terminal valine of the β chain of the globin (about 60% of glycosylated globin) Other sites are: lysin 66 and 17 of the β chain, valine of ... protein is found in a urine analysis, then a 24 hour urine collection for microalbumin or a spot urine albumin-creatinine ratio may be used (abnormal if > 30 mg albumin/ g creatinine) for screening...
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báo cáo hóa học: " Understanding and assessing the impact of treatment in diabetes: the Treatment-Related Impact Measures for Diabetes and Devices (TRIM-Diabetes and TRIM-Diabetes Device)" pdf
... method/type of diabetes medication (oral agents, insulin syringe, insulin pen or insulin pump, GLP-1 pen) Measures The following measures were administered in a validation survey battery: The TRIM -Diabetes/ Device ... manuscript MH and TC assisted in the design of the study and in the drafting of the manuscript SL assisted in the conducting of interviews, analysis of the data and the drafting of the manuscript DMB ... and injectable treatments (syringe and pen) for type and diabetes [2] This knowledge was supplemented in 2006 regarding inhaled insulin and in http://www.hqlo.com/content/7/1/83 2008 for insulin...
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báo cáo hóa học: " Health-related quality of life in diabetes: The associations of complications with EQ-5D scores" potx
... sample of members of the Norwegian Diabetes Association A large Page of proportion of the individuals with type diabetes in Norway are members of the NDA, while only a minority of those with type diabetes ... (0.3) Short-acting insulin 152 (92) 68 (19) Long-acting insulin 103 (62) 98 (28) Insulin glargine (Lantus) or insulin detemir (Levemir) 51 (31) 11 (3) Antihypertensives Cholesterol lowering drug 52 ... To investigate determinants of EQ-5D index in order to offer researchers utility data for individuals with diabetes Methods The data in this study stem from a Norwegian survey of people with diabetes...
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báo cáo hóa học: " Outcomes of adding second hypoglycemic drug after metformin monotherapy failure among type 2 diabetes in Hungary" potx
... therapies Curr Med Res Opin 2007, 23:1493-1507 Strowig SM, Raskin P: Combination therapy using metformin or thiazolidinediones and insulin in the treatment of diabetes mellitus Diabetes Obes Metab ... Severity None (%) †Mild resulting into no or little interruption in activities (%) †Moderate resulting into interruption in daily activities (%) *†Severe requiring some kind of medical or non-medical ... and clinical information this information was obtained at visit date using a survey instrument The following variables were collected: age, sex, ethnic origin, height, duration of type diabetes, ...
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báo cáo hóa học: " Pictorial Representation of Illness and Self Measure Revised II (PRISM-RII) – a novel method to assess perceived burden of illness in diabetes patients" pptx
... including cognitive debriefing sessions It is not clear if using a single question on degree of suffering in this context is indeed helpful First, it should be obvious that the concept of suffering ... amount of suffering These differences in distribution also argue in favour of measuring suffering with a visual and indirect method such as the PRISM-RII The PRISM has been proven useful in measuring ... coping efforts SIS was partly predicted by age, indicating older people on average having higher SIS scores This finding suggests more successful adaptation to the disease with increasing age In...
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báo cáo hóa học: " Fatness and fitness: how do they influence health-related quality of life in type 2 diabetes mellitus?" docx
... improvement in fitness by mL/kg·min of VO2peak was associated with a 4-point increase in general health in the final model [Additional file 1] Type diabetes was associated with an 8-point decrease in ... http://www.hqlo.com/content/6/1/110 els After scaling, changes in the HRQOL scales in the multivariate models are interpreted per mL/kg·min increase in VO2peak and per 10% increase in the percentage of body fat Statistical ... Page of (page number not for citation purposes) Health and Quality of Life Outcomes 2008, 6:110 ment in fitness by mL/kg·min of VO2peak was associated with a 4-point increase in vitality in model...
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báo cáo hóa học: " Additional impact of concomitant hypertension and osteoarthritis on quality of life among patients with type 2 diabetes in primary care in Germany – a cross-sectional survey" doc
... Quality of life in old age described as a sense of well-being, meaning and value Journal of advanced nursing 2000, 32:1025-1033 Fortin M, Bravo G, Hudon C, Vanasse A, Lapointe L: Prevalence of multimorbidity ... a lower quality of life in all domains of the SF-36 [26,27] Interestingly in our study patients with hypertension and diabetes achieved higher scores than patients with only diabetes However, ... global increase in the number of patients suffering from diabetes from 135 to 300 million patients until the year 2025 [1] Most diabetes patients suffer from type diabetes Quality of life (QoL) in...
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Báo cáo hóa học: " The effects of diabetes and/or peripheral neuropathy in detecting short postural perturbations in mature adults" pptx
... glucose and insulin levels Alterations in blood glucose and insulin levels in people with diabetes may impair the function of the vestibular system making it difficult for them to detect minor postural ... harness) during all testing Because the PEST rules are such that a series of successive misses in one interval (or correspondingly false positives in the other), would lead to ever increasing acceleration ... Weinstein monofilaments have high reliability and validity for determining sensory impairment in people with diabetes [24,25] A trained research assistant performed Berg Balance and SWM testing...
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