pathogenesis of primary essential hypertension
Báo cáo y học: "Bone morphogenetic proteins, genetics and the pathophysiology of primary pulmonary hypertension" ppt
... significance of these findings in the context of our current understanding of BMP receptor biology, and relate the data to our knowledge of inheritance patterns and disease pathophysiology of PPH Bone ... (arrowhead) (B) Control showing the same region of artery, but without addition of antibody Lu, lumen of artery (Fig 1) Comparative analysis of components of the BMP signaling pathway in different ... structural studies indicate that the plexiform lesions of PPH are composed of monoclonal foci of proliferating endothelial cells [31], and microdissection of endothelial cells from these lesions resulted...
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Báo cáo y học: " A Novel Variable Number of Tandem Repeat of the Natriuretic Peptide Precursor B gene’s 5’-Flanking Region is Associated with Essential Hypertension among Japanese Females"
... YV, et al Molecular basis of human hypertension: role of angiotensinogen Cell 1992; 71: 169-80 10 Nakayama T, Soma M, Sato N, et al An association study in essential hypertension using functional ... None of the NT subjects had a family history of hypertension; 147 all had an SBP less than 130 mmHg and a DBP less than 85 mmHg A family history of hypertension was defined as having grandparents, ... assess the contribution of confounders (gender, BMI) [17] A value of P < 0.05 was considered statistically significant Figure A: Nucleotide sequence of the 5’-flanking region of the human NPPB gene...
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Tài liệu Hypertension - Clinical management of primary hypertension in adults pdf
... improve NICE guidance and patient care in the future 4.1 Out -of- office monitoring In adults with primary hypertension, does the use of out -of- office monitoring (HBPM or ABPM) improve response to treatment? ... systolic hypertension becomes a more significant problem, as a result of progressive stiffening and loss of compliance of larger arteries At least one quarter of adults (and more than half of those ... increasing use of HBPM and for the diagnosis of hypertension as a consequence of this guideline update There are, however, very few data regarding the utility of HBPM or ABPM as means of monitoring...
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GENETICS AND PATHOPHYSIOLOGY OF ESSENTIAL HYPERTENSION doc
... disease Etiopathogenesis of essential hypertension In spite of intensive investigation, etiology of essential hypertension (EH), which accounts for 90-95% of all cases of arterial hypertension remains ... the details of many of its mechanisms We are successful in assessing the etiology of hypertension only in 5%—15% of patients Secondary hypertension most often develops on the basis of primary hyperaldosteronism, ... pathogenesis of essential hypertension is only partially understood Due to a large number of factors and pathogenic mechanisms that participate in the development and progression of hypertension its pathogenesis...
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Báo cáo y học: "Association Study of Aromatase Gene (CYP19A1) in Essential Hypertension" ppsx
... None of the controls had a family history of hypertension, and they all had SBP and DBP below 130 and 85 mmHg, respectively A family history of hypertension was defined as prior diagnosis of hypertension ... analysis Plasma concentration of total cholesterol, and serum concentrations of creatinine and uric acid were measured using the methods of the Clinical Laboratory Department of Nihon University Hospital ... Ministry of Education, Culture, Sports, Science and Technology of Japan (High-Tech Research Center, Nihon University), and a research grant from the alumni association of Nihon University School of...
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báo cáo khoa học: "Pathogenesis, diagnosis and management of primary melanoma of the colon" doc
... G: Primary malignant melanoma of the right colon Clinical Gasteroenterology and hepatlogy 2007, 5:A28 10 Tak AM: Metastatic melanoma: a case of unknown site of primary origin Internet Journal of ... regression of melanomas in their primary sites In a study of 437 cutaneous melanoma cases, 12.3% of all tumors showed at least partial regression [19] Histologic findings seen in cases of tumor ... Oncology 2011, 9:14 http://www.wjso.com/content/9/1/14 Page of Table Detailed description of the features of 12 reported cases of primary colonic melanoma in medical literature # Study Year Age/...
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study on hemodynamic index of kidney arteries and glomerular filtration rate in essential hypertension patients
... contribute to confirm the change of parameters of renal hemodynamics and glomerular filtration rate in relation to the status of hypertension in patients with primary hypertension in hypertensive ... by hypertension 25 26 LIST OF PUBLISHED PAPERS OF RESULTS RESEARCH OF THESIS Nguyễn Vĩnh Hưng, Hà Hoàng Kiệm, Đinh Thị Kim Dung (2013): “To Study the change of renal artery blood flow in essential ... with the number of glomerular hypertension unlike previous stage filtration rate of the kidneys which will decrease the high blood pressure We see more clearly in the two groups of hypertension...
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Báo cáo y học: "Ultra-low microcurrent in the management of diabetes mellitus, hypertension and chronic wounds: Report of twelve cases and discussion of mechanism of action"
... plays a major role in the pathogenesis of both types of diabetes mellitus High levels of free radicals and the decline of antioxidant defense mechanisms lead to damage of cellular organelles and ... in the pathogenesis of cardiovascular diseases including hypertension (55) Clinical studies suggest the occurrence of increased reactive oxygen species production in humans with essential hypertension ... the pathogenesis of insulin resistance in humans using magnetic resonance spectroscopy Obesity (Silver Spring) 2006;14 (Suppl 1): 34S–40S 31 Boden G Role of fatty acids in the pathogenesis of...
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Contrative analysis of primary sentences in english and those in vietnamese
... noticeable features of the structure of primary imperatives, degrees of the necessity of imperative acts, some factors affecting the force of primary imperatives, scope of using primary imperative ... analysis of primary imperative sentences in English and those in Vietnamese Structure of the primary imperative sentences According to Brown and Levinson (1978) about the structure of primary ... know degrees of necessity of primary imperative acts in English and those in Vietnamese; To help language users to understand some factors that have great influences on the force of primary imperative...
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Tài liệu Báo cáo khoa học: Role of Kupffer cells in pathogenesis of sepsis-induced drug metabolizing dysfunction pptx
... (CLP), the hepatic mRNA level of CD163 was similar with that of the sham group, which markedly decreased to approximately 7.0% of that of the CLP group (Fig 1) Table Effect of GdCl3 on serum aminotransferase ... to the inhibition of CYP activity observed in the absence of changes in protein expression in rabbit hepatocytes [22] ROS indirectly reduced the activity of selected isoforms of CYP by inducing ... role of KCs in the regulation of CYP isoform activities and gene expression profiles, partly by investigating the inflammatory signaling pathway Sham CLP GdCl GdCl3 + CLP CD163 β-actin Fig Effect of...
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Tài liệu Báo cáo khoa học: NirF is a periplasmic protein that binds d1 heme as part of its essential role in d1 heme biogenesis pdf
... demonstrated that Asp129 of NirF could not be essential for any function similar to that in Asp141 of Met8P The idea of NirF being a dehydrogenase is appealing because of the presence of a putative nucleotide-binding ... the essential role of NirF in d1 heme assembly Influence of deletion and replacement of the signal sequence on NirF processing and denitrification activity The derived amino acid sequences of NirF ... NirF and a range of nucleotide-containing cofactors by using a variety of biophysical methods (data not shown) Nonetheless, we still decided to test the effect of the deletion of the entire GXGX2GX7G...
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Tài liệu Transmission and Pathogenesis of Tuberculosis docx
... Transmission and Pathogenesis of Tuberculosis 25 Pathogenesis of TB Infection occurs when a person inhales droplet nuclei containing tubercle bacilli that reach the alveoli of the lungs These ... Further details about pathogenesis of latent tuberculosis infection (LTBI) and TB disease are described in Figure 2.3 Figure 2.3 Pathogenesis of LTBI and TB Disease Area of detail for boxes 2, ... years of age are also at increased risk for progression of LTBI to TB disease Chapter 2: Transmission and Pathogenesis of Tuberculosis 31 Table 2.6 Persons at Increased Risk for Progression of LTBI...
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Tài liệu Báo cáo khóa học: Determination by electrospray mass spectrometry and 1H-NMR spectroscopy of primary structures of variously fucosylated neutral oligosaccharides based on the iso-lacto-N-octaose core doc
... different techniques, of which MS and NMR are two of the most powerful Previously, we demonstrated the distinction of chain type and blood-group type (such as Lea/x and Leb/y) of underivatized oligosaccharides ... this report, we demonstrate our strategy of the combined use of ES-MS and NMR for analysis of the core-branching pattern and full sequence assignment of four oligosaccharides isolated from human ... voltage of 80 V was used for CID MS/MS of singly charged ions [M-H]– and 50 V for Ó FEBS 2004 1176 H Kogelberg et al (Eur J Biochem 271) Fig Product-ion spectrum of D2b-5 ion m/z 1183 of DFiLNO...
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Tài liệu The wisdom of coaching: Essential papers in consulting psychology for a world of change pot
... Table of Contents of: The wisdom of coaching: Essential papers in consulting psychology for a world of change Contributors Acknowledgments Introduction: The historical and conceptual roots of executive ... Title: The wisdom of coaching: Essential papers in consulting psychology for a world of change.Find More Like This Author(s): Kilburg, Richard R., (Ed), Office of Human Services, Johns ... surprisingly large number of arti- cantly from a relative lack of specific attention to it cles covers the application of coaching techniques i n the professional literature The purposes of this to change...
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Atmospheric volatile organic compound measurements during the Pittsburgh Air Quality Study: Results, interpretation, and quantification of primary and secondary contributions pot
... direct emission of particles (primary OC), and via emission of gas-phase precursor compounds that partition into the aerosol phase upon oxidation (secondary OC) Clarifying the roles of primary and ... subset of data dominated by primary OC [Turpin and Huntzicker, 1995; Cabada et al., 2004] This then gives a regression slope that is in theory reflective solely of primary emissions The 12 of 17 ... Photochemical production of secondary organic aerosol (SOA) depends on the chemical state of the atmosphere, both in terms of oxidative capacity, and in term of the quantity and nature of gas phase organic...
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Báo cáo khoa học: Separation and characterization of caveolae subclasses in the plasma membrane of primary adipocytes; segregation of specific proteins and functions docx
... subclass of SR-BI, which mediates binding of LDL and selective uptake of HDL cholesteryl esters and the efflux of cholesterol [30,31] SR-BI has previously been found in a caveolinenriched fraction of ... presence of at least three subclasses of caveolae, each with its specific composition: a very high-density class of caveolae at about 31% sucrose (VHD-caveolae; corresponding to 3382 Fig Outline of ... 2006 FEBS ¨ U Ortegren et al Identification of caveolae subclasses Table Constituent proteins and lipids of three subclasses of caveolae A compilation of components and properties Property Approximate...
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Báo cáo khoa học: Characterization of recombinant forms of the yeast Gas1 protein and identification of residues essential for glucanosyltransferase activity and folding pot
... characterization of Gas1p Fig Analysis of culture supernatants from Pichia pastoris-transformed cells (A) Coomassie Blue staining of 100 lL of culture supernatant at 24 and 48 h from the shift (time zero) of ... that share a low degree of conservation of the primary structure, but contain a conserved fold consisting of a (b/a)8 with the putative catalytic residues located at the end of strands b-4 and b-7 ... catalytic domain of members of Family GH72 No data are available, to date, on the role of these residues Here we have shown that C74 of the catalytic domain is crucial for the proper folding of Gas1p...
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Báo cáo khoa học: FLIP and MAPK play crucial roles in the MLN51-mediated hyperproliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis pdf
... in the pathogenesis of RA Results GM-CSF induces the proliferation of MH7A cells and the expression of MLN51 Our recent study has shown that GM-CSF is involved in the proliferation of primary ... expression in primary RA FLSs Primary RA FLS cells were treated with 100 ngÆmL)1 of GM-CSF for the periods of time shown in the figure MLN51 expression was then assessed by RT-PCR Number of cells (×104) ... express substantial amounts of metastatic lymph node 51 (MLN51) in the presence of GMCSF, and the upregulation of MLN51 is associated with the hyperproliferation of FLSs [7] MLN51 was first identified...
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The Pathogenesis of Gastrointestinal Bacterial Overgrowth pptx
... 10.1159/000081988 The Pathogenesis of Gastrointestinal Bacterial Overgrowth Einar Husebye Clinic of Medicine, Hospital of Buskerud HF, Drammen, and Division of Medicine, Ullevaal University Hospital of Oslo, ... colonization of the stomach in severe forms Features of the two main types of bacterial overgrowth, defined by the underlying pathogenesis (see text for details of the failure required to alter the microflora ... Guerrant a a Division of Geographic Medicine, Department of Internal Medicine, School of Medicine, University of Virginia, Charlottesville, Va., USA; b Department of Morphology, School of Medicine, Federal...
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pathogenesis of neurodegenerative disorders
... Pathogenesis of Neurodegenerative Disorders Contemporary Neuroscience Pathogenesis of Neurodegenerative Disorders, edited by Mark P Mattson, 2001 Neurobiology of Spinal Cord Injury, ... understand the etiology and pathogenesis of these disorders to facilitate rational development of effective therapies Numerous partially overlapping hypotheses about the pathogenesis of neurodegenerative ... increase soluble APP production High levels of Fe inhibit the maturation of APP production of downstream catabolites Iron modulation of APP may be at the level of -secretase cleavage Fe and lipid 26...
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