... working independently and with adequate reliability determined the adequacy of randomisation, concealment of allocation, blinding of outcome assessors and adequacy Page of 14 of data analysis (was intention-to-treat -analysis ... MSt, MSc and AB participated in the collection of the data andanalysisof the studies (see Materials and methods) AB and MSc participated in the study design and the interpretation of the data ... week [5] The evidence of this recommendation has not been tested by meta- analyses of head-to-head comparisons of different typesand volumes of AE Moreover, the question of whether continuing...
... tuberculosis skin testing and LTBI treatment, the prevalence and outcome of MTB infections, and the effects of patient factors and treatment on mortality from MTB infection PATIENTS AND METHODS plant ... (1/1945 to 12/ 2006), BIOSIS (1/1969 to 12/2006), and the Cochrane Database ofSystematicReviewsand Central Register of Controlled Trials and manually searched retrieved bibliographies to identify ... rate of MTB reactivation,12 some transplant centers neither test for nor treat LTBI because of the perceived lack of efficacy and potential toxicity of drug therapy in liver transplant candidates.13-18...
... this is the first systematic review and meta- analysisof the relationship between OHRQoL and tooth loss Data from our systematic review and meta- analyses of observational studies provide fairly ... Moreover, the severity of impairment might be associated with location and distribution of missing teeth, as suggested by the outcome of the meta- analysisof data of a Greek and a British population ... Summary of primary and additional outcomes of all included studies Additional file 2: Summary of data of all included studies and feasibility for meta- analysis 14 15 Author details Department of Oral...
... USA) using the user-contributed commands for meta- analyses: ‘metan’ [19], ‘metainf’ [20], ‘metabias’ [21] and ‘metatrim’ [22] In order to estimate whether the IQ of those suffering from AN differs ... (SMD) and upper and lower 95% confidence intervals of the complete study analysis Discussion The aim of this study was to provide a comprehensive systematic review of the literature including a meta- analysis ... Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta- analysis Biometrics 2000, 56:455-463 Steichen T: Nonparametric trim and fill analysisof publication...
... trial), particularly discontinuation because of adverse events or lack of efficacy This systematic review and meta- analysisof celecoxib in osteoarthritis and rheumatoid arthritis was conducted using ... intention-to-treat (number of patients randomised and receiving at least one dose of trial drug) analysis Homogeneity tests and funnel plots, though commonly used in meta- analysis, were not used ... trials of 12 weeks' duration, 46% of doses were 200 mg and 46% were of 400 mg daily In trials of 24 weeks or longer, 92% of doses were of 800 mg daily Longerlasting trials used higher doses of celecoxib...
... MMF in lupus nephritis from randomised trials and observational studies Materials and methods QUOROM (quality of reporting of meta- analyses) and MOOSE (meta- analysisof observational studies in ... numbers of patients and events increase the risk of chance findings [64] The ideal is meta- analysisof high-quality, large, randomised trials [63], but without them we have to make the best of the ... Rennie D, Stroup DF: Improving the quality of reports of meta- analyses of randomised controlled trials: the QUOROM statement Quality of Reporting of Meta- analyses Lancet 1999, 354:1896-1900 20...
... age and height The methodological features of all randomized clinical trials most relevant to the prevention of bias (including the Jadad criteria of randomization, blinding and completeness of ... of reported standard errors of these studies We used a random-effects model assessing the weighted mean difference in the meta- analysis The overall pooled analysis included the mean changes of ... pooled analysisof the treatment arms of the randomized clinical trials andof the observational studies suggested that both the FVC and DLCO predicted values improved after 12 months of therapy,...
... Haga et al.: The effect of tight glycaemic control, during and after cardiac surgery, on patient mortality and morbidity: A systematic review and meta- analysis Journal of Cardiothoracic Surgery ... Page of 10 Haga et al Journal of Cardiothoracic Surgery 2011, 6:3 http://www.cardiothoracicsurgery.org/content/6/1/3 Page of 10 Figure Results of the meta- analysis performed on the incidence of ... a median and range, and asked if they could provide their data as means and standard deviations, unfortunately, these data were not available Therefore, we conducted a meta- analysisof the three...
... 11 of 13 shoes [8,23] Unfortunately, meta- analysisof kinematic variables was restricted by inconsistencies in biomechanical models and under-reporting of standard deviations/ error Meta- analysis ... comprised the average of angle of gait relative to ipsilateral line of progression and angle of gait relative to the direction of gait The variable length comprised the average of stride and step length ... children’s shoes on gait: a systematic review and meta- analysis Journal of Foot and Ankle Research 2011 4:3 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online...
... co-segregation (higher prevalence of the endophenotype in ill relatives of ill probands than in well relatives of ill probands); and (v) heritability (the extent of variation of the endophenotype that ... al.: A systematic review and meta- analysisof neurological soft signs in relatives of people with schizophrenia BMC Psychiatry 2011 11:139 Submit your next manuscript to BioMed Central and take ... endophenotypes and biological markers offer in the early recognition of schizophrenia? Journal of Neural Transmission 2007, 119:1199-1215 Meyer-Lindenberg A, Weinberger DR: Intermediate phenotypes and...
... patients are at increased risk of complications or repeat Figure effects meta- analysisof varenicline versus placebo at weeks post-TQD Random6 Random effects meta- analysisof varenicline versus placebo ... http://www.harmreductionjournal.com/content/6/1/25 Figure Random2effects meta- analysisof all NRT trials combined versus all inert controls at weeks Random effects meta- analysisof all NRT trials combined versus all ... Jorenby DE 2.77 (1.79, 4.2 Figure Random4effects meta- analysisof smoking cessation with bupropion versus controls at 4-weeks post-TQD Random effects meta- analysisof smoking cessation with bupropion...
... Prevention and Health Promotion, Office on Smoking and Health 2006 Department of Health Department of Health and Social Services Northern Ireland, The Scottish Office Department of Health and Welsh Office: ... methods, definition of LRI outcome, characteristics of reference group, ascertainment of passive smoke exposure, passive smoke source, and timing of exposure, location of study, and age of study population, ... of a total of eight points and case-control and cohort studies out of a total of nine points A score of seven or more was chosen a priori to indicate high methodological quality Statistical analysis...
... currently the 4th-leading cause of mortality and the 12th-leading cause of disability, by the year 2020 it will be the 3rd-leading cause of death and the 5thleading cause of disability worldwide [3,4] ... to analysisof the relationship between age and gender-related differences in the annual decline in FEV1% pred Unweighted smoking status Unweighted analysisof the relationship between age and ... Figure analysisof the relationship between age and gender-related differences in the annual decline in FEV1% pred for current smokers Weighted Weighted analysisof the relationship between age and...
... critical analysisof the safety of NPPV and CPAP in the treatment of ACPE A very recent meta- analysis unfortunately addressed only some of the questions to which clinicians need answers Masip and ... pressure support ventilation Materials and methods Study design A systematic review and meta- analysisof RCTs focusing on the effect of CPAP and NPPV in the treatment of ACPE was undertaken The methodological ... mortality and risk of newly developed AMI after delivery of study interventions To improve the internal validity of this meta- analysis, we decided to consider separately trials of NPPV and CPAP,...
... TA: Meta- Analyst: software for meta- analysisof binary, continuous and diagnostic data BMC Med Res Methodol 2009, 9:80 21 The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised ... difficult), and risk Goligher et al Critical Care 2011, 15:R46 http://ccforum.com/content/15/1/R46 Page 11 of 14 Figure Forest plot of meta- analysisof studies reporting the rate of hemothorax ... analyses and report individual trial and summary results with 95% confidence intervals (CIs) To conduct meta- analyses of risks of pneumothorax and hemothorax, we first converted the proportion of patients...
... Summary of the completed checklist of quality measures for reporting ofsystematicreviewsand meta- analyses Additional File 2: Summary of search strategy Detailed summary of search terms and strategy ... as randomised? Yes Yes Was the method used to randomise described and appropriate (table of random numbers, computer generated, and so on)? Yes No Was there a description of withdrawals and dropouts? ... meta- analysisof 15 unique studies compared “early” versus “late” initiation of RRT Figure Funnel plot of all 15 studies X-axis is log of risk ratio of death Y-axis is Standard error of Log Risk ratio of...
... log-transformed upper and lower limits of 95% CI by 3.92 These data of each study were entered into the Review Manager and Comprehensive Meta- Analysis to perform meta- analysisand meta- regression analysis ... inspection of funnel plots and therefore pooled estimates may be overestimated One of this study’s strengths is that it is the first systematic review and meta- analysis on associations between frailty and ... ORs and difference in gender proportion of each study was considered to be a possible moderator causing the heterogeneity based on the findings of the subgroup analysisand meta- regression analysis...
... Equivalence of single and dual task gait speed in the prediction of falls M This systematic review and meta- analysisof 31 studies revealed that slower gait speeds under both single and dual task ... when standing and walking, which are required in many real-life situations 4.3 Strengths and limitations of the analysis This is the first meta- analysis focusing on the predictive ability of walking ... CONTRIBUTORS JM and SL contributed to the conception and design of the review JM and DS contributed to the literature searching, data extraction andanalysis JM and SL drafted the article and DS revised...
... oils’’ ‘‘(1) AND (2)’’ OR ‘‘(1) AND (3)’’ OR ‘‘(1) AND (4)’’ OR ‘‘(1) AND (5)’’ 0174 January 2007 | Volume | Issue | e20 Tobacco and Biomass Smoke and TB Figure Flow Diagram of Study Steps and Exclusions ... retrospective study Glow 29: 14–17 16 Crofton E, Crofton J (1963) Influence of smoking on mortality from various diseases in Scotland and in England and Wales An analysis by cohorts Br Med J 5366: ... pollution and TB disease Passive smoking and TB Category Table Continued Outcome (Number of Cases) Current and former use of biomass fuels, number of years cooking with biomass stoves, Current use of...