... pathogenesis ofAlzheimer s disease Major topics of neurobiological study ofAlzheimer s disease include the unraveling of the molecular mechanisms of neurofibrillary tangle formation in neuronal and ... Diagnosis ofAlzheimer s Diseaseand ‘Treatment ofAlzheimer s Disease , four luncheon seminars of ‘Strategy for BPSD’, ‘Neuroimaging of Dementia’, ‘Normal Pressure Hydrocephalus’, and ‘Treatment of ... understanding of this formidable diseaseand to share new findings among researchers in the field Clinical and basic research ofAlzheimer s disease has been the main interest of the Department of...
... Comparison of the effects of acetyl L-carnitine and amantadine for the treatment of fatigue in multiple sclerosis: results of a pilot, randomised, double-blind, crossover trial Journal of Neurological ... Mean and standard deviations for each parameter and time interval were calculated for each patient and used for further analysis Significant changes in the mean and standard deviations of these ... Cross AH, Jandorf L, Halper J, Johnson B, Morgante L, Grimson R: Fatigue therapy in multiple sclerosis: results of a double-blind, randomized, parallel trial of amantadine, pemoline, and placebo...
... analysisand helped with immunostaining and statistical analysis WWC provided critical analysisof the manuscript JG selected and provided MS samples and performed routine histopathology analysisof ... design of the study, provided critical analysisof the data, and wrote the manuscript She performed immunocytochemistry and confocal analysisof MS tissue sections JC performed the western blot analysis ... of relapsing-remitting EAE in mice, which impacted the severity of relapsing disease, of inflammation, andof demyelination, as well as the extent of axonal damage [19] We provided evidence of...
... Suicidality and divalproex sodium: analysisof controlled studies in multiple indications Annals of General Psychiatry 2011 10:1 Page 10 of 10 Submit your next manuscript to BioMed Central and take ... from the FDA meta -analysis The data summarized in this report are an individualized depiction of suicidality and DVPX, and are distinct from the aforementioned meta -analysis of 11 AEDs The studies ... http://www.annals-general-psychiatry.com/content/10/1/1 Page of 10 Table Study descriptions and number of subjects Indication Study and year of publication Description Treatment duration, weeks Dose and/ or target trough drug level...
... convincing murine model of RA is that of the recently reported DR4-IE transgenic mouse immunised with citrullinated fibrinogen [9] The impressive, though often uncontrolled, array of data that arises ... it provides more questions than answers In the case of RA, some of the answers are already partially addressed by the recent reports of new disease- specific autoantibodies In MS, the B cell autoantigens ... CEP-1 The sequence of the CEP-1 peptide is the subject of an international patent application, number WO0890360, published on 31st July 2008 The authors of this editorial, KL and PJV, are named...
... Comparison of the effects of acetyl L-carnitine and amantadine for the treatment of fatigue in multiple sclerosis: results of a pilot, randomised, double-blind, crossover trial Journal of Neurological ... assess multiple sclerosis- related fatigue MultipleSclerosis 2009, 15(12):1509-1517 Guidelines MSCfCP: Fatigue andMultiple Sclerosis: evidence based management strategies for fatigue in multiplesclerosis ... Cross AH, Jandorf L, Halper J, Johnson B, Morgante L, Grimson R: Fatigue therapy in multiple sclerosis: results of a double-blind, randomized, parallel trial of amantadine, pemoline, and placebo...
... reflecting better understanding of HIV-associated disease, the availability of new combination antiretroviral therapy, the improved care of HIV patients both outside and within the ICU, and protective ... et al.: Successful treatment of HIV-associated multicentric Castleman’s diseaseandmultiple organ failure with rituximab and supportive care: a case report Journal of Medical Case Reports 2010 ... her acute renal failure and profound metabolic acidosis (serum lactate of 18.5 mmol/L), haemofiltration was undertaken with large volume litre cycles (~90 ml/kg/hour) of lactatefree replacement...
... HIV disease may not only facilitate the understanding of genetic basis of HIV interaction with variety of blood leukocytes but also lead to the development of new biomarkers in predicting disease ... genome-wide transcriptomic analysisof ex-vivo collected CD4+ and CD8+ T cells clearly showed evidence for concerted upregulation of metabolic pathways during HIV disease progression, and a clear correlation ... profiling of CD4+ and CD8+ T cells from early infection, chronic infection, and LTNP patients has been reported [19] Interferon responses as a transcriptional signature of T cells from early and...
... the standard deviation of the residuals from the style analysisof the hedge fund strategy S using the nine indices, σI is the standard deviation of the residuals from the style analysisof the ... concept of concordance and discordance which informally says that a pair of random variables are concordant if large values of one tend to be associated with large values of the other and small ... estimates the standard error of the parameter estimate by the empirical standard deviation of the B replications The result is called the bootstrap estimate of standard error and is evaluated...
... Overlay of sewered area Overlay of sewered area and households Separation of unsewered households Fig - Separation of unsewered households of Minasebashi basin of Mizunashi River - 147 - Journal of ... calculation of pollution load of the individual basin, on the basis of the results of the river flow survey (Fig 17) In the case of Mizunashi River and the upstream basins of Kuzuha River, because of ... Journal of Water and Environment Technology, Vol 9, No.2, 2011 data of Japan and the data of each drainage basin were prepared in GIS and were calculated based on area proportion (Fig 4) Land use...
... different shapes of micro-channels which have been already developed and newly designed as well The result ofanalysis shows that characteristics of flow such as velocity, uniformity, and flow rate, ... 2.73 K), and this leads to prevent drying out of the membrane and excessive thermal stresses that may result in rupture of the membrane, and therefore less thermal management problems, and achieve ... 2.69 K), and this leads to prevent drying out of the membrane and excessive thermal stresses that may result in rupture of the membrane, and therefore less thermal management problems, and achieve...
... stand out for their frequent use of lexis to express notions of increase and decrease The English texts used were minutes of the meetings of the Monetary Policy Committee of the Bank of England, ... occurrences 24 of increase, increasing, increases and increased The results of this analysis are presented in Tables and 4, below Table 3a: Expressions of increase, Bank of England Monetary Policy ... studies of different aspects of economics discourse in recent years, several of which are published in Dudley-Evans and Henderson (1990) and Henderson, Dudley-Evans and Backhouse (1993) The first of...
... formal ones Modality Modality often appears in both two kinds of letters with a great deal of number The use of active and passive voice Our analysisof two kinds of letter shows that: the passive ... language of publicstic literature, the language of newspapers, the language of scientific prose, the language of official documents.Take the following words and sentences for example: heart disease, ... difference on production and reception We use our mouths and ears for spoken discourse and our hands and eyes for witten one Brown and Yule (1983:13 ) point out that spoken and written discourse...
... Complementary and alternative medicine andmultiplesclerosis Allen C Bowling—2nd ed p ; cm Rev ed of: Alternative medicine andmultiplesclerosis c2001 Includes bibliographical references and index ... Complementary and Alternative Medicine andMultipleSclerosis Second Edition This page intentionally left blank Complementary and Alternative Medicine andMultipleSclerosis Second Edition ... published in lay and professional publications, and have been presented to lay and professional audiences A number of organizations and individuals provided valuable advice, information, and financial...
... details of how the annotations are done can be found in (Ayan et al., 2005) and (Ittycheriah and Roukos, 2005) 3.1 Align SU SG SI SA SB Phrase Lengths ofand Table presents the precision, recall, and ... from that of AER but is identical to that of CPER (with a phrase length of 3) for Chinese On the other hand, in Arabic, both AER and CPER provide a slightly different ranking from that of BLEU, ... 2005; Ittycheriah and Roukos, 2005; Taskar et al., 2005) The standard technique for evaluating word alignments is to represent alignments as a set of links (i.e., pairs of words) and to compare...
... Computer-assisted mass spectrometric analysisof cross-links L J de Koning et al Fig Part of the output sheet of the VIRTUALMSLAB analysisof the MALDI-FTICR-MS data of the RNase A digest peptide mixture ... or in any desired order; and (b) in and out filtering of defined reaction products Our aim is to establish general, rapid and relatively simple procedures for the analysisof naturally occurring ... range the density of the candidate peptide masses is relatively low The levelling-off points out that the distribution of the alternative candidate peptide masses around the mass of the authentic...
... validity of each of the interpretations constructed by the analysis module, with the proof context; (E) evaluate the proof-relevant part of the utterance with respect to completeness, accuracy, and ... should be that element ofAnd if it should be that , it as well.] must be an element of where the predicate apply takes two arguments: one of sort RULE and the other of sort TERM or FOR MULA, ... Generic and specific references can appear within one utterance: ] Our goal is to provide a uniform analysisof inputs of varying degrees of verbalization This is achieved by the use of one grammar...