omics studies of fetal development in down syndrome and future directions
Báo cáo y học: "Gene-dosage effects in Down syndrome and trisomic mouse models" pot
... among individuals such that there were examples of individual genes showing no increases in comparisons of individual Down- syndrome- euploid pairs (see also below) Importantly, these variations in ... all individual pairwise comparisons showed similar increases Indeed, of the 37 genes, only 24 showed increases in 18 or more of the 36 possible pairs Because these mice are maintained on an inbred ... midbrain, in each case pooling RNAs from four individuals, aged 3-4 months Expression of 66 trisomic genes was detected in at least one of the nine tissues In eight tissues, overall levels of expression...
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Báo cáo khoa học: "Automatic Measurement of Syntactic Development in Child Language" docx
... using the same data, the mean point-to-point accuracy of CP was 85.4% (a relative increase of about 100% in error) In their separate evaluation of CP, using 30 samples of typically developing ... grammar induction Proceedings of the 40th Annual Meeting of the Association for Computational Linguistics (pp 128-135) Dekang Lin 1998 Dependency-based evaluation of MINIPAR In Proceedings of the ... analysis in section 5.3, it is clear that the identification of certain GRs needs to be made more accurately We intend to annotate more in- domain training data for GR labeling, and we are currently investigating...
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Aptitude for Destruction, Volume 2 - Case Studies of Organizational Learning in Five Terrorist Groups pptx
... commercially and another informal in the form of repeated experimentation The few instances of formal training focused on specialized expertise in how to operate things The informal training focused ... assets of safety and security of individuals in transit and in their workplaces and communities The ISE research portfolio encompasses research and analysis on a broad range of policy areas including ... highly devoted to Asahara were involved in planning, developing, and using the weapons The key Aum members included the heads of Aum’s “ministries” and those involved in the group’s “Household Agency”...
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Báo cáo khoa học: P NMR studies of energy metabolism in xanthosine5¢-monophosphate overproducing Corynebacterium ammoniagenes pot
... (glu/glc) induced a significant increase in XMP production, and this increase in XMP production was coupled with a reduction in production of the by-product, hypoxanthine XMP production attained nearly ... which specifically occurs during XMP production In fact, an increase in ATP concentration and ATP/ADP ratio could be induced during phase I by increasing glu concentration in the culture medium (Fig ... (phase II), suggesting that hypoxanthine production was induced through a switch in the carbon flux In Table 1, glu increased the XMP/Hyp ratio, being dependent on the increased level of glu/glc ratio...
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delphi - fundamentals of database development in delphi
... Microsoft as a part of Windows 98/2000 If you or your client use Windows 95 or Windows NT you will probably need to distribute and install the ADO engine Delphi 5's CD includes an installation of ... fields to the list Use dragging and dropping (as explained in the 5th chapter) to link a data−aware DBEdits to fields in a database table 22 Posting When linking components in a way that the DBNavigator ... stored and how we are accessing it You can use the same connection string as in the second chapter, or you can build one by invoking the connection string editor Setting the LoginPrompt property of...
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Báo cáo hóa học: " Variation in rates of early development in Haliotis asinina generate competent larvae of different a" pptx
... idiosyncratic rates of development are present within a single cohort of synchronously fertilised, and genetically related (full sibling) H asinina larvae Differences in the rate of development produce ... Production of embryos and larvae All gametes were produced from natural spawnings of H asinina following methods previously described [4,56] Gravid broodstock were maintained in individual spawning ... three independent fertilizations Figure Variation in the rate of third cleavage revealed by nuclear staining (A - F) Propidium iodide staining of early H asinina embryos allowed the number of discrete...
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Báo cáo vật lý: "Volumetric and Thermodynamic Studies of Molecular Interactions in Ternary Liquid Mixtures at 303, 308 and 313K" pptx
... value of viscosity increased with increasing concentrations of 1alkanols and decreased with increasing temperature As the number of hydrocarbon groups or the chain-length of the alcohol increased, ... the density, and R is the gas constant It is stated that in the case of liquid systems, including electrolytic solutions, there is no serious harm in assuming cubic packing and equating b to 3.3 ... measurements at 303, 308 and 313K The main purpose of this study is to characterize the molecular interactions in these systems and subsequently to determine the effect of the chain length of 1alkanols EXPERIMENTAL...
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Báo cáo y học: "Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function" pptx
... 4°C, and then paraffin blocks were prepared using standard histological procedures For nitrotyrosine staining, the sections were deparaffinized and hydrated, and then were immunostained using ... A: Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1beta and with chondrocyte resistance to insulin-like growth ... clarify the relationship between oxidative damage and development of OA, immunostaining for nitrotyrosine was examined in the donor-matched pair of intact and degenerated articular cartilage sections...
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Báo cáo y học: "ncreased serum HO-1 in hemophagocytic syndrome and adult-onset Still''''s disease: use in the differential diagnosis of hyperferritinemia" docx
... µg of total RNA, 200 nmol/l of probe, and 800 nmol/l of primers were incubated in 25 µl at 50°C for 2min and 95°C for 10min, followed by 40 cycles of 95°C for 15s and 60°C for The amounts of ... diagnosis of HPS and ASD and for monitoring disease activity Further studies are required to determine the mechanism and sources of increased serum HO-1 in these diseases Clarification of the relation ... activity and abnormal levels of perforin are involved in the macrophage activation syndrome of systemic-onset juvenile rheumatoid arthritis [20] Dysfunction of NK and cytotoxic cells may lead to inadequate...
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Báo cáo y học: "Biology and therapy of fibromyalgia: pain in fibromyalgia syndrome" ppsx
... 27% of the variance of overall clinical pain [26], thus emphasizing the important role of peripheral impulse input for FM pain These findings represent a possible link between peripheral input and ... during acute pain While defining the relationship between tissue events and pain is necessary for understanding the clinical context of these pathologies, defining the relationship between injury ... summation of second pain or windup First pain, which is conducted by myelinated A-δ pain fibers, is often described as sharp or lancinating and can be readily distinguished from second pain by most...
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Báo cáo y học: "Systematic review and meta-analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus nephritis" pdf
... residual bias in observational studies and lack of blinding in randomised trials The amount of information for MMF is greater than for cyclophosphamide and azathioprine in this indication, and trials, ... differences, the main findings of both randomised trials and cohort studies were much the same Complete plus partial response with MMF occurred in 66% of patients in randomised trials and in 80% in cohorts, ... the original authors (mainly urine protein excretion, serum creatinine or creatinine clearance, or a combination of these) and subsequent relapse Adverse events sought included mortality, infection...
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báo cáo khoa học: "C-band variants of telocentric chromosomes in swine : evidence and inheritance studies" ppt
... Within an individual the defined variants for both homologues were constant However, in pairs 13 and 15, the differences in C-band size were not as distinct as in pairs 16, 17, and 18, and in ... (1981) The aims of the present paper are : (1) description of different C-band size variants of telocentric !1> chromosomes of pigs and (2) inheritance studies of the clearly defined C-band variants ... to the definition of a polymorphism, the variants should be distinct, discontinuous, and inherited Variability in C-band size in porcine chromosomes has been described by several ELANDER -M ANSEN...
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Báo cáo y học: "Development of daily rhythmicity in heart rate and locomotor activity in the human fetus" ppt
... recordings obtained were processed by the calculation of maternal and fetal heart rate (FHR) in 5-minute intervals and transferred onto the cardiotachogram representing a graph of intra-minute ... done according to the following parameters: hourly fluctuations in maternal and fetal HR, intra-minute fluctuation of HR, and baseline rhythm The baseline was defined as the level obtained at a.m., ... prevalent during "quiet" hours as during "active" hours Statistical processing of the findings regarding the duration of each type of the oscillations and "active" and "quiet" hours of the fetus...
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Báo cáo y học: "Profiling of cellular proteins in porcine reproductive and respiratory syndrome virus virions by proteomics analysis" pps
... protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity In response to DNA damage, proliferating cell nuclear antigen protein is ubiquitinated and involved in the ... cytoskeleton system proteins, which have the maximum profusion among the identified cellular proteins, including Actin, Keratin, Annexin, Coronin, Tubulin, Tropomyosin, and Cofilin Enveloped viruses ... phospholipid-binding protein family members play a vital role in the regulation of cellular growth and signal transduction pathways S100 calcium binding protein with EF-hand calcium-binding motifs...
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báo cáo khoa học: " Mutations in a plastid-localized elongation factor G alter early stages of plastid development in Arabidopsis thaliana" docx
... abundance was similar in wild-type and sco1-1 seedlings (Figure 4) Since the EMS mutation in sco1-1 converts a glycine contained within the GTP-binding domain to an arginine, transcription was ... embryos are in the early stages of desiccation and the onset of dormancy, and chloroplasts are beginning to dedifferentiate [11] Since Figure Development of sco1-1 embryos Development of sco1-1 ... example, studies in various plant species indicated that protein initiation factors and elongation factors, including elongation factors EF-G and EF-Tu, are present in the nuclear genome and contain...
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Báo cáo y học: "Efficacy of different types of aerobic exercise in fibromyalgia syndrome: a systematic review and meta-analysis of randomised controlled trials" potx
... pain) Risk of bias within studies Only two studies fulfilled all predefined criteria of internal and external validity (see Table 1) Results of individual studies The means, SDs, sample sizes and ... significant effect of AE on pain at post treatment, except for a combination of waterbased and land-based AE, total duration of AE >2,000 minutes, frequency of training or >3 times/week and intensity ... Main characteristics of studies with aerobic and mixed exercise in fibromyalgia syndrome The file contains the main characteristics of studies with aerobic and mixed exercise in fibromyalgia syndrome...
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Báo cáo khoa học: "Clinical review: The implications of experimental and clinical studies of recruitment maneuvers in acute lung injury" pptx
... above the lower inflection point was more effective in maintaining gas exchange and minimizing inflammation and lung injury than was PEEP set at the maximum curvature of the deflation pressure–volume ... collapse lead to upregulation of an inflammatory response, with release of cytokines and chemokines and activation of neutrophils and macrophages that produce lung damage [2] Injurious MV can lead to ... expression of many cytokines involved in the pathogenesis of VILI [14] It is unknown whether a single stimulus such as RMs applied during MV can trigger the above-mentioned pathways of lung injury, and...
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Báo cáo y học: " Divergent evolution of arrested development in the dauer stage of Caenorhabditis elegans and the infective stage of Heterodera glycin" pot
... shock proteins, proteins related to transcription and translation (for example, elongation and splicing factors and RNA polymerase II) and structural proteins, including tubulin and actin, as well ... Silent information regulator protein Down Down Down Down Down Down Down Down Down Down Down HgAffx.24343.1.S1_at 657 B0334.1 5e-28, 115, 46% 6e-31, 126, 49% Transthyretin-like HgAffx.2920.1.S1_at 578 ... planted in a 2:1 sand:soil mixture in the greenhouse Two weeks after planting, each pot, containing an average of to germinated seedlings, was inoculated with 15,000 to 20,000 H glycines strain OP-50...
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Báo cáo y học: "Global transcriptome analysis reveals circadian regulation of key pathways in plant growth and development" potx
... genes ('C+E intersection') at the intersection of the combined Covington and Edwards datasets contains almost all of the circadian genes found by analysis of the individual Covington and Edwards ... transcripts, including the following: RNA processing; DNA synthesis and chromatin structure; protein synthesis, secretion, and ubiquitin-mediated degradation; G-proteinmediated signaling; and cell ... -carotene Zeinoxanthin zeinoxanthin -carotene Zeaxanthin zeaxanthin Lutein lutein Violaxanthin violaxanthin ABA Figure Circadian co-regulation of metabolic pathways Circadian co-regulation of metabolic...
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ROLE OF ADENOSINE A1 RECEPTORS IN NATIVE CORONARY ATHEROSCLEROSIS, IN-STENT STENOSIS, AND CORONARY BLOOD FLOW REGULATION IN METABOLIC SYNDROME AND EXERCISE
... course of the following weeks During the 4th through the 7th week of training, a typical 70 minute training session consisted of the following: 1) minute warm-up at 2.5 mph, 2) 15 minute sprint ... media, and adventitia (Figure 1.1B) The intima is lumenal to the internal elastic lamina and includes the inner cellular lining of the vascular wall, i.e endothelium Media is bounded by internal and ... displayed in the Ossabaw miniature swine model of MetS and CAD 13 Figure 1.3A shows Picrosirius red staining as another index of collagen and elastin This atherosclerotic lesion shows a thin fibrous...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25