... Hence T has a fixed point (3.27) 176 Fixed points of multimaps Similarly, we get the following corollary, which extends [11, Theorem 2] to non-selfmultimaps and to spaces satisfying the nonstrict ... subsets of X The Kuratowski and Hausdorff measures of noncompactness of a nonempty bounded subset of X are, respectively, defined by α(B) = inf {d > : B can be covered by finitely many sets of diameter ... The characteristic of noncompact convexity of X associated with the measure of noncompactness φ is defined inthe following way: φ (X) = sup ≥ : ∆X,φ ( ) = (2.7) N Shahzad and A Lone 171 Note...
... Health and Quality ofLife Outcomes 2008, 6:29 Background Inthe period following wars and other forms of armed conflict, health and quality oflifeof mothers is a major concern as they have the ... years old selected randomly from households in Kabul Province, Afghanistan Random sampling was conducted based on the list developed with the cooperation and supervision ofthe Expanded Programme ... regard to basic needs Experience of hardships over the last decade consisted of lack of food, water and shelter was assessed Resources seeking for mental health support To examine the coping mechanism...
... β-actin promoter, increasing of titers of antibody (reaching a peak in 21 day after infection), and increasing the survival rate, showing 100%, 100% and 95% in injection with 10 µg, 30 µg and ... collection of RNA molecular generates the important role of transcriptome in cells by inthe case of containing the coding RNAs that specify the composition ofthe proteome and determine the biochemical ... capacity ofthe cell The RNA sequence shows the sequence of its transcribed DNA (Brown, 2002) Based on analyzing the entire collection of RNAs in a cell facilitates determining the beginning and ending...
... participated inthe recruitment of patients and clinical data analysis MC participated inthe design and coordination ofthe study AMK participated inthe conception and design ofthe study and critically ... revised the manuscript JCA participated inthe conception and design ofthe study andinthe interpretation of data and helped to draft the manuscript All authors read and approved the final manuscript ... study entry All ofthem exhibited an active disease defined as at least six swollen joints, at least nine tender joints, and morning stiffness for more than hour, regardless of being under treatment...
... albumins On the other hand, the direct thermodynamic and kinetic characterization of Ni(II) binding at site I in HSA and BSA was obtained These data can be very useful in further studies ofthe ... presumably providing metal binding at site II andthe neighbouring His242) bind phosphate ions, thereby providing another level of competition for metal ion binding Kinetics of Ni(II) binding and Cu(II)/Ni(II) ... differences inthe conformation ofthe chelate rings The characteristic alternate pattern ofthe dd bands inthe CD spectra is dictated by the conformation ofthe sixmembered chelate ring involving the...
... nucleotide-binding sites (site and site 2) that comprise the Walker A and Walker B motifs of one NBD andthe linker domain ofthe other Inthe absence of Mg2+, there is little difference in ATP block of ... the average ofthe individual NBDs), indicating that the NBDs must interact, and emphasizing the functional importance ofthe last 42 amino acids of SUR2 One possibility is that interaction of ... the NBDs of SUR2A [22] SUR2A and SUR2B differ onlyintheir last 42 amino acids, which not form part ofthe catalytic site Thus, these amino acids may interact with the NBDs to modulate binding...
... CGATCGGGGCGGGGCGAGC-3¢ (underlined bases denote the functional core ofthe MREs andthe Sp1 binding element, andthe mutated bases are indicated by italic type) Western blot analysis The MREa-binding proteins purified ... Microsequencing analysis ofthe MREa-binding proteins (A) The N-terminal sequence ofthe 82-kDa band was identical to amino-acid positions 6–16 ofthe Ku-80 protein (B) The 70-kDa band did not ... polyvinylidene difluoride membrane, andthe individual proteins were subjected to N-terminal sequencing The N-terminus ofthe 70-kDa protein was blocked by modification Therefore, the protein was...
... has on the lives of hundreds of thousands of people every year We have made huge steps forward in improving survival andin preventing thousands of new cases ofthe disease, both inthe UK and ... for the future, pioneering the development and provision of relevant training in our Institutes and Centres and working in partnership where possible - Maintain our current investment in training ... understanding ofthe disease Increasingly we are using our website to make information easily accessible, using different formats, suchas our science blog We will increasingly use both video and...
... [15,16] and TP [17] Homology modeling-based mutagenesis ofthe TM domains ofthe prostanoid receptors suggested that the conserved regions ofthe third and seventh TM domains are involved in binding ... the N-terminus andthe C-terminus of eLP2, which could then result in a conformational change ofthe ligand recognition site within the eLP2 region Another hypothesis is that the main chain distance ... for the ligand interaction inthe eLP2 region of TP The residues that lost binding activity inthe mutagenesis studies are labeled inthe 3D model of TP side chain of Ala might directly block the...
... now assumed the title ofthe Company ofthe Indias The Company next acquired the privilege of farming all the taxes andthe whole revenue ofthe kingdom; and presently bought out the mint, andthe ... from the king; one the Bank of Scotland, in 1695; the other, the Royal Bank of Scotland, in 1727 These two banks have branches in most ofthe principal towns of Scotland; but as they never obtained ... expense, and to vast profit For, as banknotes, provided their payment was secure, had been determined to be the same thing as coin; and as, according to the mercantile theory, coin was the same thing...
... Internet Engineering Task Force “Random acts of senseless violence and destruction will continue and expand due to a feeling of 21st century anomie, and an increasing sense of lack of individual ... amassed The early 1990s predictions are available in a searchable database online at the site Imagining the Internet: A History and Forecast and they are also the basis for a book by Anderson ... connected to the network, thus continuing the divide between the 'have' and 'have not.'“ And Matthew Allen, president ofthe Association of Internet Researchers and associate professor of internet...
... A.%)+%&!(8)* The story ofthe shark Why does the shark win? The story ofthe shark Why does the shark win? Why doesn’t the shark win? It’s a fucking shark The story ofthe shark Why does the shark win? ... Jeffrey Beall The story ofthe shark Hong Kong The story ofthe shark Hong Kong From The Art of Finding Nemo” by Mark Cotta Vaz (Pixar) The story ofthe shark Shark vs my Kinect drawings? 9(+%:;6&
... Some ofthe challenges that need to be overcome arethe following • Location awareness is increasingly important This includes awareness ofthe personal surroundings, the tracking and positioning ... concepts and discussed their relevance in Page of 14 the context ofthe internet ofthings This next section describes in more detail on how IDRA can support two important internet ofthings use cases: ... a single software function These software services are dynamically combined to form ad hoc applications In regards to the internet of things, SOAs have two main disadvantages [32]: (1) SOAs focus...
... for the proposed metadirectory includes defining the naming context, which is the top level name for the metadirectory namespace, and defining the organizing structure ofthe metadirectory andthe ... More ofthe Mas to Use More Information Manually Join the Remaining Ambiguous Entries During the planning phase, you identified the connected directories to integrate with the metadirectory, and ... metadirectory planning phase will be used during the design and development ofthe metadirectory The following table identifies the phase inthe design and development process inwhich each the functional...
... are maintained (Figure 1b) Thus, asthe retinal circuit matures, dendritic arbors refine but the density of inputs per bipolar cell is retained by the increase inthe density of synapses on the ... when the dendritic arbor actively enlarges and also refines by pruning back dendrites, the number of synaptic contacts per unit area ofthe bipolar cell surface is maintained by the increase in ... that the dendritic arbors of RGCs begin to stratify both their branches andtheir synapses at thetime when synaptic glutamate neurotransmission begins (postnatal days 7-12 inthe mouse) During...
... meaning; for example, if R and W are red and white points we would have R W and W < R Furthermore, the green and blue points are increasing, the red and yellow points are decreasing, andthe ... indeed yield a pair of increasing and decreasing subsequences whose union is σ The left-hand side ofthe equation inthe lemma therefore counts the number of increasing, decreasing pairs (α, β) ... green since R G and R and G arethe maximal red and green points under “ ” Thus at least one of them, P say is yellow Since the yellow points are decreasing and Y is the smallest yellow point under...
... effects inthe injected joint, it is becoming increasingly clear that local treatment also affects arthritis in nearby joints This is an intriguing and general finding, which may expand the therapeutic ... naïve joints A conflicting finding was the protection ofthe ipsilateral hind paw by adenoviral overexpression of IL-10, which was seen inthe absence of a local anti-inflammatory response inthe ... controlled by the kinase activity of cyclin/cyclindependent kinases andtheir inhibitors p16 (INK4a) and p21 (Cip1) Forced overexpression of either p16 or p21 by adenoviral vector transduction ofthe synovium...
... heparin administration at thetimeof withdrawal of lifesustaining treatment asthe current standard of care [3,7] The acceptability of these practices should be evaluated according to Beauchamp and ... hypotension – and therefore hasten death Nevertheless, there is no evidence that heparin leads to sufficient bleeding afterthe withdrawal of life- sustaining therapies to cause death [7] The guidelines, ... provision of certain forms of care at the end oflife that result indeath [11] A practical example of this principle is the use of narcotics for pain relief, although respiratory depression and death...