of and inflammatory responses to human and ovine b parapertussis strains in

báo cáo hóa học: " Inhibition of microglial inflammatory responses by norepinephrine: effects on nitric oxide and interleukin-1β production" pdf

... Schotanus K, Steinbusch HW, Schoffelmeer AN, Berkenbosch F: Gradual inhibition of inducible nitric oxide synthase but not of interleukin-1 beta production in rat microglial cells of endotoxin-treated ... IL-1β levels in the incubation media were assessed by ELISA; and (B) NOS2 activity in the cells measured by increase in net DCF fluorescence (total RFU minus the RFU obtained by preincubating cells ... (KT5270 and H-89) and activators (dbcAMP), the AC inhibitors (SQ 22536 and MDL-12,330A), the interleukin receptor antagonist (IL-1ra) and the irreversible cell permeable caspase-1 inhibitor (Ac-YVAD-CMK)...

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the trade and trade policy implications of different policy responses to societal concerns

Danh mục: Kế toán tài chính

... set Finally, enforcement consists of systems ensuring standards and labels are truthful, and involves tracking and tracing mechanisms The cost of labelling is often part of the production and ... is both to try to understand better the processes whereby policy responses have been developed and to examine the extent to which the solutions described are trade distorting or not THE TRADE AND ... taxes and subsidies or various combinations of these are being used according to the mix of objectives to create the right incentives and governance framework for the sector Stakeholders in the...

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Báo cáo y học: "Inhibition of allogeneic inflammatory responses by the Ribonucleotide Reductase Inhibitors, Didox and Trimidox" pot

Danh mục: Báo cáo khoa học

... inhibitors, Didox and Trimidox, to act as inhibitors of inflammatory responses by both inhibiting the proliferation of T-cells and the production of cytokines Discussion In this study, we determined ... Penicillin/Streptomycin (Gibco BRL 10,000 units per ml penicillin +10,000 mg/ml streptomycin sulphate in 0.85% saline), and maintained in an incubator (Queue: Cell culture incubator) at 37°C and ... dose of Didox inhibiting cytokine levels comparable to that in NC Trimidox inhibited cytokine production more vigorously than Didox with a dose of 25 μM inhibiting IL-10, IL-13, and IL-4 by approximately...

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Báo cáo khoa học: " The cross-reactivity of the enterovirus 71 to human brain tissue and identification of the cross-reactivity related fragments" ppsx

Danh mục: Báo cáo khoa học

... verified by immunohistochemical staining with a monoclonal antibody of EV71 (Millipore) Large area of neuron apoptosis was observed in cerebrum and medulla of brain tissue In small intestine, intestinal ... antigens of the EV71 with human brain tissue, however, the brain binding partner of EV71 induced IgG was not identified in this work The peptides that elicit antibodies can bind to human brain tissue ... permeability after EV71 infection in infant mice and further more, the increase of BBB permeability after EV71 infection could result in the entrance and localization of the IgG into brain tissues...

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Báo cáo y học: " Mitogen-activated protein kinases and NFκB are involved in SP-A-enhanced responses of macrophages to " pdf

Danh mục: Báo cáo khoa học

... Figure bone marrow inhibits BCGHerbimycin A macrophages and SP-A-BCG killing by rat Herbimycin A inhibits BCG- and SP-A-BCG killing by rat bone marrow macrophages RBMM were incubated with BCG or ... importance of these kinases in controlling microbial infection are the findings that pathogenic strains of various bacteria block inflammatory mediator production through inhibition of MAP kinases ... Herbimycin A inhibits BCG- and SP-A-BCG-induced producHerbimycin A inhibits BCG- and SP-A-BCG-induced production of nitric oxide BCG were collected by centrifugation, and then suspended in PBS SP-A...

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Proteomics analysis of pro inflammatory cytokine stimulated human lung fibroblasts and bronchial epithelial cells

Danh mục: Cao đẳng - Đại học

... epithelial cells in vitro and in 10 vivo, serving as a source of fibroblasts during lung fibrosis (Willis and Borok, 2007) TGF-β also induces the transformation of fibroblasts into myofibroblasts which ... protein profilings of normal human bronchial epithelial cells (NHBE) and normal human lung fibroblasts (NHLF) stimulated with pro -inflammatory cytokines tumor necrosis factor (TNF)-α and/ or interferon ... signaling pathways by TNF-α Upon contact with its ligand, TNF receptor enables the adaptor protein TRADD to bind to the death domain, serving as a platform for subsequent protein binding Following...

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Tài liệu Báo cáo khoa học: Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages docx

Danh mục: Báo cáo khoa học

... genetically obese (ob ⁄ ob) and streptozotocin diabetic mice Diabetes Res 11, 125–129 24 Odani H, Shinzato T, Matsumoto Y, Usami J & Maeda K (1999) Increase in three a ,b- dicarbonyl compound levels in human ... to be sufﬁcient to inhibit lysosomal degradation of modiﬁed proteins Interestingly, apoB from oxidized LDL has 1536 been shown to accumulate in secondary lysosomes in macrophages because of inefﬁcient ... FEBS B E Brown et al with LDL glycated using glycolaldehyde or methylglyoxal, and either a mAb to CD36 [47], the SR-A inhibitor fucoidin, or AGE–HSA, which is known to bind to RAGE [48] The inhibition...

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Báo cáo y học: " Possible transmission of HIV Infection due to human bite" potx

Danh mục: Báo cáo khoa học

... (Figure 1) During the incident the thumb nail of (Mr.A) came out leaving behind a raw bleeding nail bed Clinical examination of (Mr.X) revealed that his oral hygiene was good, absence of oral ulcers, ... The case thus indicates acquisition of HIV infection through saliva not contaminated with blood, following a human bite The blood samples of both the father-son duo and saliva of the source (Mr.X) ... detection of HIV infection for monitoring responses to ARV therapy Conclusions Our observations revealed transmission of HIV infection from the smear of non-contaminated saliva of [Mr.X] on the raw and...

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Báo cáo y học: "hytol-based novel adjuvants in vaccine formulation: 2. assessment of efficacy in the induction of protective immune responses to lethal bacterial infections in mice" ppsx

Danh mục: Báo cáo khoa học

... on inflammatory cytokines (IL-6 and TNF-α) In order to determine whether adjuvants exert any effects on induction of inflammatory cytokines, such as IL-6 and/ or TNF-α, the levels of these cytokines ... proinflammatory cytokine production (IL-6 and TNF-α) in response to bacterial vaccine Effect of6 Effect of adjuvants on proinflammatory cytokine production (IL-6 and TNF-α) in response to bacterial ... antibody response Efficacy of adjuvant in sustaining antibody response induced The durability of antibody response elicited due to inclusion of adjuvants in the vaccine was determined 30 and...

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Báo cáo y học: "Inflammatory responses to acute pneumovirus infection in neonatal mice" pps

Danh mục: Báo cáo khoa học

... symptom complex of nasal congestion, tachypnea, and diffuse expiratory wheezing, much of which is thought to be caused by virus-induced inflammatory responses In contrast, human newborns infected ... responses to PVM infection in newborn mice will provide further insights into the ontogeny of the innate immune response and ultimately a better understanding of the mechanisms involved in neonatal ... Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland Drs Domachowske and Rosenberg are long-time collaborators with shared interests in inflammation...

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Báo cáo y học: " Prevalence of a virus similar to human hepatitis B virus in swine" ppt

Danh mục: Báo cáo khoa học

... the finding of HBV in pigs will enhance our understanding of the virology and immunology of HBV infection and disease pathogenesis, including major sequelae like chronic hepatitis and hepatocellular ... though a vaccination program for newborn babies has been in place since the 1990s, the incidence of hepatitis B is still increasing, from 21.9 in 100,000 people in 1990 to 53.3 in 100,000 in 2003 ... exists in swine populations And thus brings about a lot of questions Does these pigs infected by HBV? Does swine hepadnavirus exist? Does this virus related to the rising of hepatitis B in human...

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firewalking - a traceroute-like analysis of ip packet responses to determine gateway accessing

Danh mục: Chứng chỉ quốc tế

... can determine the following: § The number of hops in between our attacking host and the target firewall This information allows us to deterministically control the port number of the probe that ... protocol on top on IP If we attempt to traceroute to a machine behind a firewall and the probe reaching the firewall is prohibited by an ACL filter, the packet will be dropped on the floor (in ... have the affect of breaking valid uses of traceroute and may inhibit remote diagnostics of an internal network problem Another defense against Firewalking is the use of some form of proxy server...

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báo cáo hóa học:" Aflatoxin levels, plasma vitamins A and E concentrations, and their association with HIV and hepatitis B virus infections in Ghanaians: a cross-sectional study" pdf

Danh mục: Hóa học - Dầu khí

... decreased ability to detoxify aflatoxin metabolites leading to higher concentrations of these metabolites in the blood Aflatoxin can also cause liver disease since it induces injury to both hepatic ... Aflatoxin has been shown to injure both hepatic parenchyma and the biliary tract [45] Thus, aflatoxin likely damages the liver’s vitamin A functioning, and the combination of HIV and aflatoxin ... liver synthesis (albumin and total protein) The normal range values were based on those in the University of Alabama Hospital Laboratories Bulletin of Information (revised October 2002) Statistical...

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Báo cáo y học: "Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro" pps

Danh mục: Báo cáo khoa học

... Differences in the loss of proteoglycan and chondrocyte between cultures incubated with different mABs tures incubated with different mABs (a) Loss of toluidine blue staining between cultures incubated ... explants and compared the results with a nonarthritogenic mAb to CII, CIIF4, and to an irrelevant mAb, GAD6, in the absence of inflammatory mediators known to dominate the effector phase of CIA Both ... (b) CIIC1 and (c) M2139 The area of colour indicates antiantibodies body binding (d) The control mAb (GAD6) shows no binding to the cartilage Figure A toluidine blue stained sections of cartilage...

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Báo cáo y học: " Documenting the experiences of health workers expected to implement guidelines during an intervention study in Kenyan hospitals" ppt

Danh mục: Báo cáo khoa học

... training and introduction of evidence-based guidelines In accompanying papers or in previously published work we have described: the development of the evidencebased clinical practice guidelines ... that combined initial training with limited reinforcement training, supervision, feedback and local facilitation over a period of 18 months [8] This package of interventions was felt to be appropriate ... ETAT+ training or other introduction to the guidelines The aim of sampling was to ensure that the maximum variation in opinion might be captured, and thus continued until the point of saturation...

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báo cáo khoa học: " Documenting the experiences of health workers expected to implement guidelines during an intervention study in Kenyan hospitals" ppsx

Danh mục: Báo cáo khoa học

... training and introduction of evidence-based guidelines In accompanying papers or in previously published work we have described: the development of the evidencebased clinical practice guidelines ... that combined initial training with limited reinforcement training, supervision, feedback and local facilitation over a period of 18 months [8] This package of interventions was felt to be appropriate ... ETAT+ training or other introduction to the guidelines The aim of sampling was to ensure that the maximum variation in opinion might be captured, and thus continued until the point of saturation...

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Báo cáo sinh học: " Genetic parameters for resistance to the Salmonella abortusovis vaccinal strain Rv6 in sheep" ppt

Danh mục: Báo cáo khoa học

... Genetics of Salmonella resistance in sheep Table I Number of offspring, sires and dams by series Sex Parents Offspring M F M F M+F Batch (mating in October 94) 15 255 198 218 416 Batch (mating in July ... Considering these observations and practical husbandry restraints, the chosen slaughtering time corresponded to the end of the spleen infection (10 days after inoculation) and to the beginning of ... studying resistance to parasitism [17] But, to our knowledge, nothing has been published about salmonellosis CONCLUSION A number of traits were measured in a large number of animals to obtain a better...

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Báo cáo khoa học: Sodium pump a1 and a3 subunit isoforms mediate distinct responses to ouabain and are both essential for survival of human neuroblastoma docx

Danh mục: Báo cáo khoa học

... further Ouabain-induced signaling in SK-N-AS cells Ouabain and other CTS induce signaling cascades in a variety of cells and also in the neuroblastoma cell line SH-SY5Y [7,21,22] One of the ﬁrst ... signaling induced by CTS is due to inhibition of the sodium pump and a local increase in intracellular [Na+] followed by a subsequent increase in [Ca2+] in the small space between the plasmalemma and ... mediate CTS-induced activation of Erk1 ⁄ in SK-N-AS cells when it has been shown to be involved in CTSinduced signaling in various other cells? This question can be addressed by taking into consideration...

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báo cáo khoa học: "Local suffering and the global discourse of mental health and human rights: An ethnographic study of responses to mental illness in rural Ghana" pptx

Danh mục: Báo cáo khoa học

... approaches to facilitating access to mental health services and working with families include involving family members in providing treatment and combating stigma [52], and the training of village ... families and healing practitioners within rural communities in Ghana, to gain an understanding of how practices such as the chaining and beating of those with mental illness are embedded within sociocultural ... chaining and beating were used for punishment and discipline as well as restraint within the prayer camps and shrines Informants described how people were beaten with sticks, belts and strips of...

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Báo cáo y học: "Incidence of Ocular Zoonoses referred to the Inflammatory and Autoimmune Ocular Diseases Service of the University of Parma - Italy"

Danh mục: Y học thưởng thức

... of Parma (Italy) References Mora P, Vecchi M, Barbera L, Toscani M, Orsoni JG Use of systemic cyclosporin A in a case of severe Toxocara uveitis J Infect 2006; 52:159-161 http://www.medsci.org ... Int J Med Sci 2009, 119 this case the patient had a panuveitis, which recovered only after a combination of medical treatment and surgery, with a final visual acuity of 40% in the affected ... The only case of Lyme disease affected a 31 year-old farmer and his ocular manifestations are described in the specific section Figure 1: Geographical location of the province of Parma (Italy)...

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of and inflammatory responses to human and ovine b parapertussis strains in sheep