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odor images in mice and humans mapping odor space within brain space

Báo cáo khoa học: Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans docx

Báo cáo khoa học: Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans docx

Báo cáo khoa học

... thyroglobulin (670 kDa), c-globulin (158 kDa), ovalbumin (44 kDa), myoglobin (17 kDa) and vitamin B12 (1.35 kDa) standards (Lower) Fractions containing standards and analyzed proteins of (1) GST–mSPS1 and ... whereas the side chain in mice and C elegans has nine units and that in S pombe and humans has ten isoprene units [17] One type of ubiquinone is dominant in each organism but a minor type(s) is also ... synthases in mice and humans, we can ask which component is more important in determining the chain length of ubiquinone by replacing either component with homologs from other species and analyzing...
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Báo cáo y học:

Báo cáo y học: "Escape from X inactivation in mice and humans" potx

Báo cáo khoa học

... event in X inactivation during embryo­ genesis, and gene silencing follows within one or two cell cycles [7] Interestingly, Xist-induced silencing can only be achieved in early differentiating ... marks from being added to escape domains (Figure 2) Supporting this idea are our findings that the insulator protein CTCF (CCCTCbinding factor), which binds known insulator sequences, binds to the ... Kdm5c and the inactivated gene Iqsec2 (IQ motif and SEC7 domain-containing protein 2) in mouse, whereas in humans, the corresponding region between the same genes, which both escape X inactivation,...
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Báo cáo khoa học: Differential expression pattern of the novel serine⁄threonine kinase, STK33, in mice and men doc

Báo cáo khoa học: Differential expression pattern of the novel serine⁄threonine kinase, STK33, in mice and men doc

Báo cáo khoa học

... anti-a-tubulin in green) (D–I) Immunostaining combined with nuclear staining in mouse lung preparations (anti-Stk33 in red and nuclear staining in blue) (D,E,F) Alveolar macrophages showing cytoplasmic ... protein kinases discriminate between serine ⁄ threonine and tyrosine? Structural insights from insulin receptor protein-tyrosine kinase FASEB J 9, 1255–1266 Supplementary material The following ... antibody staining Immunoreactivity is observable in recombinant protein (Rec), protein extracts from testis of mice at 20 and 30 dpp but absent in 10 dpp Coomassie blue staining of total protein shows...
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cooperation in primates and humans mechanisms and evolution -  peter m. kappeler

cooperation in primates and humans mechanisms and evolution - peter m. kappeler

Sinh học

... settle for grooming partners of adjacent rank and trade grooming in kind In species that form matrilineal dominance hierarchies, kin occupy adjacent ranks Thus, kin biases in grooming reflect the ... partners, then kin biases in interactions patterns among siblings, cousins, grandmothers and grandchildren, and other kinds of maternal kin may emerge The dynamics of social interactions 39 40 ... of interest between egotism and nepotism by maximizing their own rank among their kin on the one hand, and by maximizing the rank of their kin in relation to non-kin on the other (p 129) 2.4 Kin...
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báo cáo hóa học:

báo cáo hóa học: " Effects of betaine on lipopolysaccharide-induced memory impairment in mice and the involvement of GABA transporter 2" doc

Toán học

... Chung HY: Betaine suppresses proinflammatory signaling during aging: the involvement of nuclear factor-κB via nuclear factor-inducing kinase/IκB kinase and mitogenκ κ activated protein kinases J Gerontol ... [5] In the central nervous system, it has been reported that betaine content and BGT-1 mRNA levels are increased in brain of rats with hyperosmotic serum induced by the injection and drinking ... catecholamines in the rat brain I The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain J Neurochem 1966, 13:655-669 24 Chomczynski P, Sacchi N: Single-step...
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Báo cáo hóa học:

Báo cáo hóa học: " La Crosse virus infectivity, pathogenesis, and immunogenicity in mice and monkeys" docx

Hóa học - Dầu khí

... Immunohistochemical stain c Hemotoxylin and eosin stain ing nuclear vacuolization and cell shrinkage (Figure 4B C) To identify cell infiltrates in a moribund mouse, brain sections were immunostained using anti-CD3 ... collected in North Carolina and passaged once in mouse brain and three times in Vero cells LACV/human/ 1978 was isolated from post-mortem brain tissue collected in Wisconsin and passaged once in mouse ... titers for nasal turbinates, brain, spinal cord, muscle, and serum were in agreement with findings in Figure (data not shown) Histopathologic lesions in the brain (including areas of the olfactory...
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Báo cáo y học:

Báo cáo y học: "The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis" doc

Báo cáo khoa học

... inflammation and cartilage degradation were inhibited by blocking IL-1β but not IL-1α In RA patients, IL-1β is overexpressed in inflamed synovial tissue, in particular in the lining layer and in sublining ... before randomization; active disease at screening; baseline evaluation (same evaluator) indicating more than six tender and six swollen joints out of 28 examined (including any effused joint); and ... The main elicitor of inflammatory responses in preclinical animal models appears to be IL-1β and not IL-1α In murine collagen-induced arthritis [6] and antigen-induced arthritis [7,8], inflammation...
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Báo cáo y học:

Báo cáo y học: "Effect of a structurally modified human granulocyte colony stimulating factor, G-CSFa, on leukopenia in mice and monkeys" docx

Báo cáo khoa học

... the addition of methionine, arginine, glycine, and serine residues at the amino-terminus and with cysteine-17 replaced by alanine as predicted (Figure 1B) To determine the in vitro activity of ... in data acquisition, analysis and interpretation WJ conducted in vitro experiments including protein purification and analysis WD was involved in the analysis and interpretation of data as well ... serine residues in the amino-terminus of G-CSFa that results in a more positive charge in the amino-terminus of G-CSFa may further enhance the binding between the cytokine and its receptor This...
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Báo cáo y học:

Báo cáo y học: " Safety assessment of inhaled xylitol in mice and healthy volunteers" ppsx

Báo cáo khoa học

... ng/ml was measured in the chamber during the exposures The mice underwent a baseline methacholine challenge on day 17 and subsequently underwent exposures to saline and xylitol using the same protocol ... saline and xylitol exposure on methacholine responsiveness in naïve mice (n = 6/group) Panel A reflects methacholine responsiveness before and after saline exposure Panel B reflects methacholine ... such as CF and dyskinetic cilia syndrome and certain acute clinical entities such as ventilator-associated pneumonia There is a continuing need for simple, cost-effective, and safe intervention...
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Báo cáo y học:

Báo cáo y học: "The dosage-compensation complex in flies and humans" ppt

Báo cáo khoa học

... high-affinity binding sites for the DCC, which the complex can bind even when it is missing certain subunits In addition, there could be many binding sites of lower affinity throughout the remainder ... defects in the cell cycle and in nuclear morphology The molecular changes underlying these phenotypes remain to be established Understanding the function of DCC-related complexes in flies and mammals ... ISWI-containing remodeling factor is involved in the assembly of H1-containing chromatin He proposed that the reason only the X chromosome lacks H1 is that the small maternal contribution of ISWI in...
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Báo cáo sinh học:

Báo cáo sinh học: "Comparison of different delivery systems of DNA vaccination for the induction of protection against tuberculosis in mice and guinea pigs" pps

Báo cáo khoa học

... DNA priming and protein boosting after a single-dose vaccination Materials and methods Animals Outbred Female Hartley guinea pigs weighing 300–350 g and young adult BALB/c mice were obtained from ... capable of sustaining the protective response in mice and guinea pigs Therefore, using biodegradable microspheres in a single dose seems to be a promising strategy for stimulating long-lasting immune ... advantage for the vaccines Table 2: Bacterial replication in lungs from mice and guinea pigs vaccinated and challenged with M tuberculosis Vaccine formulationsa Miceb Guine-pigsb No vaccination BCG DNAv...
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An examination of the lived experiences of malaysian chinese in singapore and the functional importance of their diasporic spaces

An examination of the lived experiences of malaysian chinese in singapore and the functional importance of their diasporic spaces

Tổng hợp

... Singapore, their capacity to adapt and adjust to living in Singapore and their opinion of Singaporeans and Singapore The interviews were conducted in English, Mandarin and Hokkien, with each interview ... translation of certain interview transcripts from Mandarin and Hokkien to English and the lack of comprehension of certain informants who may espouse certain phrases in Malay and other Chinese dialects ... fundamental in their enactment of their “sense of Chinese-ness” (Nonini, 1997) Younger Malaysian Chinese, however, may be inclined to observe a “disembedding of place” (Nonini, 1997) in that China and...
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Báo cáo y học:

Báo cáo y học: " Polysaccharides from the root of Angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice

Y học thưởng thức

... shown to protect mice against hydrocoticoid-induced inhibition of IFN-γ, IL-2, IL-4 and IL-10 transcription [24] In addition, vitamin B12, folinic acid and biotin identified in AP may also contribute ... glycerol), containing 1.0 mM phenylmethylsulfonyl fluoride and μg/ml aprotinin Samples were then centrifuged at 12,000 rpm for 20 at °C and the supernatant containing total protein was denatured and separated ... cross-linking DNA strands and activation of p53-dependent growth arrest and apoptosis [28] It was therefore not surprising that CY administration resulted in a decrease in the proliferating cell...
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CHAPTER ELEVEN MIND MAPPING   a NEW DIMENSION IN THINKING AND NOTE TAKING

CHAPTER ELEVEN MIND MAPPING a NEW DIMENSION IN THINKING AND NOTE TAKING

Kỹ năng thuyết trình

... exercise in the power of the Mind Map technique, try 'reading' in detail the Mind Map on the Brain Training and Mind Mapping Course, to see how comprehensive a summary/understanding you can obtain ... Symbols c Numbers d Letters e Images f Colours g Dimension h Outlining On page 109 is a Mind Map summarising a three-day Brain Training and Mind Mapping Course The Mind Map was made by a father ... outstanding are 108 Fig 10 A Mind Map by a company director, summarising the Brain Training and Mind Mapping Course The central image refers to the integration of the brain and the body The branches...
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A contrastive analysis of idioms denoting humans with dispraising implications in english and vietnamese

A contrastive analysis of idioms denoting humans with dispraising implications in english and vietnamese

Khoa học xã hội

... Hence, dialogue writing and role-play are useful and interesting activities for learners learners’ in meaningful describing and and efficient when teaching idioms A list of idioms in learners’ native ... following: A Contrastive Analysis of Proverbs Denoting Humans with Dispraising Implications in English and Vietnamese An Investigation into Idioms Denoting Humans with Praising Implications in English ... idioms which denote a certain aspect of human beings aiming to criticize or dispraise humans in an indirect way fixed in their form and any substitutions and rearranging in their structure can lead...
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Tài liệu Báo cáo khoa học: RMI1 deficiency in mice protects from diet and genetic-induced obesity pptx

Tài liệu Báo cáo khoa học: RMI1 deficiency in mice protects from diet and genetic-induced obesity pptx

Báo cáo khoa học

... observable Interestingly, the RMI1 mRNA level increased significantly in the liver and intra-abdominal fat of the obese phenotype mice; however, that in the skeletal muscle did not increase, and that in ... strain and the Ay mutation were investigated using F1 mice Only male mice were used for the KK-Ay experiment For examination of the effects of high-fat feeding, 4-week-old mice were fed a diet in ... RMI1+/+ between and h after glucose injection (E) Plasma insulin concentrations during the oral glucose tolerance test (F) AUC for plasma insulin levels between and 0.5 h after glucose injection Values...
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Báo cáo Y học: Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice pdf

Báo cáo Y học: Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice pdf

Báo cáo khoa học

... leptin levels Insulin and leptin levels in the plasma of mice were determined spectrophotometrically by ELISA (Linco/Millipore, ApoE and obesity Billerica, MA, USA; cat no EZRMI-13K for insulin, ... and leptin levels in these mice, serum samples were isolated at weeks and 24 of the experiment and analyzed for insulin and leptin At week 0, all three mouse groups had similar plasma insulin levels ... ApoE3knock -in mice, 0.12 ± 0.05 ngÆmL)1 for ApoE)/) mice, and 0.16 ± 0.01 ngÆmL)1 for C57BL/6 mice) At week 24, ApoE3knock -in and C57BL/6 mice had elevated plasma insulin levels, with concentrations in...
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Báo cáo khoa học: Neuroglobin and cytoglobin expression in mice Evidence for a correlation with reactive oxygen species scavenging doc

Báo cáo khoa học: Neuroglobin and cytoglobin expression in mice Evidence for a correlation with reactive oxygen species scavenging doc

Báo cáo khoa học

... Betts DM & Grozdanic S (2006) Neuroglobin and cytoglobin: oxygen-binding proteins in retinal neurons Invest Ophthalmol Vis Sci 47, 1016–1023 Stein I, Itin A, Einat P, Skaliter R, Grossman Z & Keshet ... neuroglobin and cytoglobin in rat brain Brain Res 1096(1), 173–179 Schmidt M, Gerlach F, Avivi A, Laufs T, Wystub S, Simpson JC, Nevo E, Saaler-Reinhardt S, Reuss S, Hankeln T et al (2004) Cytoglobin ... concentration of Ngb in the mouse retina is > 100 lm, and is thus within the range of Mb in the muscle, indicating the important role of Ngb in retinal function [18] However, in contrast to Mb, the O2 affinity...
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Báo cáo khoa học: Benzo[a]pyrene impairs b-adrenergic stimulation of adipose tissue lipolysis and causes weight gain in mice A novel molecular mechanism of toxicity for a common food pollutant doc

Báo cáo khoa học: Benzo[a]pyrene impairs b-adrenergic stimulation of adipose tissue lipolysis and causes weight gain in mice A novel molecular mechanism of toxicity for a common food pollutant doc

Báo cáo khoa học

... by low doses of norepinephrine exerted a significant inhibition on lipoysis (Fig 1C) The initial step involved in the epinephrine ⁄ norepinephrine-induced lipolytic cascade includes activation ... Thus, B[a]P exerted an inhibitory effect on epinephrine-induced lipolysis both in murine white and brown adipocytes B 10 ANP-induced FFA release (mM mg/prot) Epinephrine-induced FFA release (mM/mg ... lgÆkg)1 epinephrine (d) or saline (s), or (B) 0.5 mgÆkg)1 B[a]P for the indicated times prior to receiving injections of either saline or 0.25 mgÆkg)1 epinephrine Forty-five minutes after injection...
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báo cáo hóa học:

báo cáo hóa học:" TRIP-Br2 promotes oncogenesis in nude mice and is frequently overexpressed in multiple human tumors" ppt

Hóa học - Dầu khí

... TRIP-Br for binding to PHD zinc finger- and/ or bromodomain-containing proteins, arrests proliferation and induces caspase-3-independent sub-diploidization in cancer cells in vitro [23] In summary, ... protein-protein interactions THD2 consists of one or more PEST signals rich in proline, serine and threonine residues, while THD3 harbors a novel PHD zinc finger- and/ or bromodomain-interacting ... cancers, including prostate carcinoma, squamous cell lung carcinoma, lung adenocarcinoma, ovarian cystadenocarcinoma, colorectal carcinoma, renal cell carcinoma, osteosarcoma and hepatocellular carcinoma...
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