nutritional support in cancer and transplant patients

Tài liệu Post-discharge nutritional support in malnourished ill elderly patients pptx

... function includes time measures of walking speed, rising from a chair, putting on and taking off a cardigan, and maintaining balance in a tandem stand(21-23) To test walking performance a meter walking ... the intervention group received standardized nutritional support starting in hospital and continuing until three months following discharge:  Energy and protein enriched diet (during the in- hospital ... limitations and increasing body weight Therefore, nutritional intervention, consisting of protein, energy, vitamin D, and calcium, may be a promising, cheap, and easy intervention strategy to maintain...

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Pharmacokinetics and pharmacogenetics of mycophenolic acid in asian renal transplant patients in singapore

Danh mục: Cao đẳng - Đại học

... activation Induction immunosuppression and treatment of acute rejection Cyclosporine (Sandimmune®, Neoral®) Binds to cyclophilin, resulting in cyclophilin-cyclosporine complex which inhibits calcineurin ... protein binding of MPA .76 3.3.3.2 Human plasma protein binding of MPAG 76 3.3.3.3 Effect of MPAG on human plasma protein binding of MPA77 3.3.3.4 Effect of MPA on human plasma protein binding ... phosphatase and Tcell activation Maintenance immunosuppression Tacrolimus (Prograf®) Binds to FK506-binding protein 12 (FKBP12), resulting in FKBP12tacrolimus complex which inhibits calcineurin phosphatase...

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Báo cáo khoa học: The dipeptidyl peptidase IV family in cancer and cell biology pot

Danh mục: Báo cáo khoa học

... gastrointestinal tract, skin, lymph node, spleen, liver and lung, as well as in pancreatic acinar cells, adrenal gland, spermatogonia and spermatids of testis, and in Purkinje cells and in the ... cell line have revealed roles for DP9 in cell adhesion, in in vitro wound healing, in cell migration, and in proliferation and apoptosis, and roles for DP8 have been found in wound healing, in cell ... Cell-surface CD26 ⁄ DPIV interacts with adenosine deaminase, CARMA-1 and caveolin-1 Stimulation of CD26 causes IRAK-1 and Toll-interacting protein to disengage from caveolin-1, resulting in the phosphorylation...

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báo cáo hóa học:" RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation" pptx

Danh mục: Hóa học - Dầu khí

... propagates inflammatory responses and is a significant RAGE ligand in the setting of sepsis and acute inflammation HMGB1 is an apparent autocrine/paracrine regulator of monocyte invasion, involving ... upregulation of inflammation in this setting [181] Another RAGE ligand, AGE-CML, is present in endoneurial and epineurial mononuclear cells in chronic inflammatory demyelinating polyneuropathy and vasculitic ... has role in shuttling HIPK2 (homeodomaininteracting protein kinase 2) to the cytosol Abundantly expressed in undifferentiated and proliferating embryonic cells but usually undetectable in adult...

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Báo cáo sinh học: "Detection and characterization of translational research in cancer and cardiovascular medicine"Ơ docx

Danh mục: Hóa học - Dầu khí

... structures, policy initiatives, or clinical concerns? Developments in cancer research in the 1990s, including rapid advances in understanding of cancer genetics and increasing use of surface ... however, the sole clinical mix journal in the set, maintains links to both the clinical domain and the molecular biology domain This journal plays a key role linking diverse research interests while ... used methods and techniques One interesting set are the guidelines and criteria of various sorts seen in both the cancer plot (Boland 1998, Mountain 1997, Therasse 2000, Sobin 2002) and the cardiac...

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báo cáo hóa học:" Detection and characterization of translational research in cancer and cardiovascular medicine" potx

Danh mục: Hóa học - Dầu khí

... structures, policy initiatives, or clinical concerns? Developments in cancer research in the 1990s, including rapid advances in understanding of cancer genetics and increasing use of surface ... however, the sole clinical mix journal in the set, maintains links to both the clinical domain and the molecular biology domain This journal plays a key role linking diverse research interests while ... used methods and techniques One interesting set are the guidelines and criteria of various sorts seen in both the cancer plot (Boland 1998, Mountain 1997, Therasse 2000, Sobin 2002) and the cardiac...

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Báo cáo y học: "Binge eating symptomatology in overweight and obese patients with schizophrenia: a case control study" ppt

Danh mục: Báo cáo khoa học

... controls have binge eating symptomatology ation and maintenance of the WG phenomenon observed in at least part of patients with schizophrenia Finally, management of AP induced WG should take into account ... leptin levels increase rapidly after initiation of clozapine therapy Mol Psychiatry 1998, 3:76-80 Theisen FM, Linden A, Konig IR, Martin M, Remschmidt H, Hebebrand J: Spectrum of binge eating ... Freeman LM, Gil KM: Daily stress, coping, and dietary restraint in binge eating Int J Eat Disord 2004, 36:204-212 MB F, Spitzer RL, M G, J W: Structured clinical interview for DSM-IV-TR Axis I disorders-...

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Báo cáo y học: "Catechol-O-methyltransferase gene haplotypes in Mexican and Spanish patients with fibromyalgia" docx

Danh mục: Báo cáo khoa học

... 'sympathetically maintained pain' [5] Naturally occurring sympathetic neurotransmitters are catecholamines known as norepinephrine, epinephrine, and dopamine All three substances act within the central nervous ... explains the multifaceted complaints of FM [4] The defining characteristics of FM (namely, widespread pain and allodynia) could be explained by a pathogenesis known as 'sympathetically maintained ... system Norepinephrine acts also in peripheral postganglionic nerve endings and exerts local effects in close proximity to the area where it is released, whereas epinephrine is the circulating hormone...

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Báo cáo y học: "A randomised controlled comparison of early post-pyloric versus early gastric feeding to meet nutritional targets in ventilated intensive care patients" ppsx

Danh mục: Báo cáo khoa học

... contained sicker patients, which may have influenced feeding and outcome And finally, our patient population is largely medical and therefore, may not represent findings in a surgical group of patients ... Lopez-Martinez J: Multicenter, prospective, randomized, single-blind study comparing the efficacy and gastrointestinal complications of early jejunal feeding with early gastric feeding in critically ... feeding has been examined in a number of studies In general, the results have largely been equivocal Both Ho and colleagues and Marik and colleagues confirmed this in two metaanalyses [30,31] Individual...

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Báo cáo y học: "Mean glucose during ICU admission is related to mortality by a U-shaped curve in surgical and medical patients: a retrospective cohort study" docx

Danh mục: Báo cáo khoa học

... glucose and mortality We await further studies, but according to these findings, we recommend treating hyperglycemia in the ICU in a moderately intensive way in both medical and surgical patients, ... arterial, and venous glucose values in patients receiving intensive intravenous insulin therapy after cardiac surgery Am J Clin Pathol 2007, 127:919-926 32 Marik PE, Preiser JC: Toward understanding ... lower and upper parts, is described earlier in patients with myocardial infarction during admission [20-22], more generally in patients with type diabetes mellitus [23], and in the ICU setting...

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Clinical pharmacokinetics of tacrolimus in asian liver transplant patients

Danh mục: Tổng hợp

... (Kershner and Fitzsimmons, 1996) In an investigation to determine the clinical utility of monitoring Tac blood concentrations in liver transplant patients involving 111 subjects from transplant ... diluted in % dextrose or normal saline and administered as a continuous infusion over 24 hours to minimize the nephrotoxicity of the drug Ointments containing Tac for the topical treatment of skin ... Asian adult and paediatric liver transplant patients and its parameters 125 25 Final population PK model of Tac in Asian liver transplant patients and its parameters estimated using FOCE 26 Case...

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Báo cáo y học: " Factors affecting the long-term response to tacrolimus in renal transplant patients: Pharmacokinetic and pharmacogenetic approac"

Danh mục: Y học thưởng thức

... of a combination of a calcineurin inhibitor (tacrolimus) with a purine inhibitor (mycophenolate mofetil or azathioprine) and a steroid (prednizolone) Tacrolimus was given twice a day in individually ... seriousness, co-administrated drug therapies and their interactions, renal and hepatic function, nutritional and other habbits, are often responsible for the intra- and inter-individual variability ... Hesselink DA, van Schaik RH, van der Heiden IP, et al Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus Clin...

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Báo cáo hóa học: " Comparison of T-cell receptor repertoire restriction in blood and tumor tissue of colorectal cancer patients" docx

Danh mục: Hóa học - Dầu khí

... carcinoma patients, unaffected colonic mucosa, carcinoma tissue) one has to keep in mind the differences in sample sizes and applied tests The highly significant difference in CD between blood and ... patients confirming the results of former studies investigating Vβ-repertoire restrictions in blood of patients with other tumor entities, which have been interpreted as indication for the induction ... origin, we found a negative correlation between HAC/PBGD and CD (Figure 3) as well as HAC/PBGD and n(F) (not shown) However, separate analysis of the samples originating from blood and originating...

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báo cáo hóa học:" CCR9 interactions support ovarian cancer cell survival and resistance to cisplatin-induced apoptosis in a PI3K-dependent and FAK-independent fashion" pdf

Danh mục: Hóa học - Dầu khí

... growth inhibition of OVCAR-3 and SKOV3 cell lines caused by cisplatin in a CCR9-dependent fashion CCL25-induced cisplatin resistance of OvCa cell lines Treatment of OVCAR-3 and SKOV-3 cell lines ... performed in triplicate Asterisks (*) indicated statistical differences (p < 0.01) between untreated and treated cells Chemokines-chemokine receptor interactions also support integrin clustering, ... chemokine receptor/ G-proteins and independent of FAK activation These results support our hypothesis that CCL25-CCR9 interaction promotes OvCa survival and resistance to cisplatin Competing interests...

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báo cáo hóa học:" Leucine-rich alpha-2-glycoprotein-1 is upregulated in sera and tumors of ovarian cancer patients" pot

Danh mục: Hóa học - Dầu khí

... cystadenomas were defined as having benign pathology, patients Page of 14 with clear cell and serous ovarian cancer were defined as having cancer and patients diagnosed as having low malignant potential ... protein were present in both ovarian cancer and NOSE cell lines (Figure 3B); the predominant form detected in all cases was 47 kD Interestingly, four of the five serous ovarian cancer cell lines, ... experiments using sera, tissue, and cell lines from ovarian cancer patients and non -cancer controls Methods Serum samples Serum from patients with serous ovarian carcinoma (n = 58) and healthy...

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báo cáo hóa học:" Pain in cancer. An outcome research project to evaluate the epidemiology, the quality and the effects of pain treatment in cancer patients" pptx

Danh mục: Hóa học - Dầu khí

... strategies, and called for a prospective program of research aimed at making available to treating physicians, patients and families valid information about pain management in cancer Two main lines ... double-blind, placebo-controlled study Pain Clinic 2003, 15:193-202 Farar JT, Halpern SD: Understanding clinical trials in pain research In Cancer Pain, Assessment and Management Edited by: Bruera ED, ... from Industry, Scientific Societies and Patients Associations was convened by the Mario Negri Institute on November 2003 to discuss the quality of pain management in cancer patients in Italy and, ...

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Báo cáo khoa học: "Ultrasound-guided central venous catheterization in cancer patients improves the success rate of cannulation and reduces mechanical complications: A prospective observational study of 1,978 consecutive catheterizations" pps

Danh mục: Báo cáo khoa học

... and other major complications indicates that US guidance should be mandatory for CVC insertion in patients with cancer Background Central venous access is essential in patients with cancer, and ... catheter in the internal jugular vein [19] In addition, a report in the United States also showed that

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Báo cáo khoa học: "Incidence of synchronous appendiceal neoplasm in patients with colorectal cancer and its clinical significance" docx

Danh mục: Báo cáo khoa học

... colon cancer and rectal cancer Considering this reason, a larger number of incidental appendectomy in patients with leftsided colon cancer and rectal cancer are warranted to verify our findings ... Cystadenocarcinoma of the appendix: an incidental imaging finding in a patient with adenocarcinomas of the ascending and the sigmoid colon BMC Gastroenterol 2003, 3:30 Lyda MH, Noffsinger A, Belli ... one study determining such an incidence [7] Khan and Moran retrospectively reviewed 169 CRC patients who underwent CRC surgery and removal of the appendix in Basingstoke, United Kingdom They reported...

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Báo cáo khoa học: "Early clinical experience with volumetric modulated arc therapy in head and neck cancer patients" ppsx

Danh mục: Báo cáo khoa học

... the initial clinical experience with head and neck RapidArc patients, in terms of dosimetric analysis and acute toxicity results Methods and materials Patients selection This is a single-Institute ... contoured by the planner and included as follow: spinal cord, brain stem, left and right parotids; larynx and uninvolved oral cavity were outlined whenever not heavily included in the target Whenever ... Volume (GTV) was defined as the gross extent of tumour shown by imaging, including all involved (positive) lymph nodes MRI, and in few cases FDG-PET, were used in the delineation of GTV On the...

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Báo cáo khoa học: "Dysphagia in head and neck cancer patients following intensity modulated radiotherapy (IMRT)" pptx

Danh mục: Báo cáo khoa học

... (SIB) in head and neck cancer patients Radiat Oncol 2006, 1:7 Feng Y, Kim MHyungjin, et al: Intensity-Modulated Chemoradiotherapy Aiming to Reduce Dysphagia in Patients With Oropharyngeal Cancer: ... was mainly involved /in charge with the clinical post treatment follow up visits of all patients All authors read and approved the final manuscript Page of 8 10 11 12 13 14 15 16 17 Competing interests ... swallowing structures was routinely performed by drawing a laryngo-pharyngeal midline ‘shielding’ contour outside the PTVs in all cases This sparing structure has been defined prospectively in January...

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