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nitrite and nitrate in ischemia reperfusion injury

Báo cáo y học:

Báo cáo y học: "Ipsilateral common iliac artery plus femoral artery clamping for inducing sciatic nerve ischemia/reperfusion injury in rats: a reliable and simple method" doc

Báo cáo khoa học

... MN participating in drafting the manuscript RR participating in drafting the manuscript and statistical analysis GF participating in statistical analysis and study design MRR: Preparing the revised ... embedded in paraffin, and finally, sections were stained with hematoxylin, eosin and tri-chrome gomori for light-microscopy studies, and were graded for ischemic fiber degeneration (IFD) and edema ... 1°C) and maintained on a 12 h light/dark cycle with free access to food and water All experiments were performed in accordance with institutional guidelines for animal care and use and also "Principles...
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Báo cáo y học:

Báo cáo y học: "CXC-chemokine regulation and neutrophil trafficking in hepatic ischemia-reperfusion injury in P-selectin/ICAM-1 deficient mice" docx

Báo cáo khoa học

... ligand for β2-integrins, and α4-integrins (α4β1/VLA-4 and α4β1/VCAM-1), could be potential candidates [30-34] In addition, neutrophils also express CD11d/CD18 and α9-integrin, which both bind ... the ischemic and non-ischemic liver lobes were fixed in buffered 10% formalin, embedded in paraffin, and used for hematoxylin and eosin (H&E) staining Other portions of ischemic and non-ischemic ... and ischemia- reperfusion injury in rat liver Am J Physiol 1991, 260:G355 Jaeschke H, Hasegawa T: Role of neutrophils in acute inflammatory liver injury Liver Int 2006, 26:912-9 Lobb RR: Integrin-Immunoglobulin...
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Báo cáo y học:

Báo cáo y học: "Low-dose vasopressin infusion results in increased mortality and cardiac dysfunction following ischemia-reperfusion injury in mice" potx

Báo cáo khoa học

... result in vasopressin-inducing vasoconstriction and cardiac dysfunction in the injured heart Conclusions AVP infusion significantly depressed the myocardial function in I/R injured model and increased ... Vasopressin infusion results in higher mortality following I/R of the LAD than saline or dobutamine When compared with infusions of either saline or DOB, vasopressin results in dramatically increased ... baseline and day following I/R of the LAD Left ventricular tissue was dissected and flash frozen for protein extraction both in control (baseline) animals and at day following ischemia/ reperfusion...
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Báo cáo sinh học:

Báo cáo sinh học: "Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction" ppt

Hóa học - Dầu khí

... for estimating daily urine volume and measuring the ratio of urine protein to urine creatinine excretion Quantification of urine protein, BUN, and creatinine level was performed using standard laboratory ... and creatinine, urine amount, and the ratio of urine protein to creatinine Serum levels of blood urea nitrogen (BUN) and creatinine and the ratio of urine protein to creatinine in three groups ... Creatinine and BUN, Urine Amount and the Ratio of Urine Protein to Creatinine after IR Procedure Three time points (i.e 24 h, 72 h, and day 14 after the IR procedure) were chosen for determining...
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Báo cáo sinh học:

Báo cáo sinh học: "The combined transduction of copper, zincsuperoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury" ppt

Hóa học - Dầu khí

... CK, CK-MB, cTnT and MDA, indicating that PEP-1-SOD1 and PEP-1-CAT cooperatively protected heart against ischemia- reperfusion injury by removing OFR Ischemia- reperfusion injury induces myocardial ... ischemia- reperfusion injury To observe whether transduced PEP-1-SOD1 and PEP-1CAT protect myocardial ischemia- reperfusion injury in Page of 11 vivo, we established the model of myocardial ischemiareperfusion injury ... hypoxiareoxygenation injury [25,26] Our previous studies have shown that application of PEP-1-SOD1 or PEP-1-CAT can tranduced into myocardium and protected against myocardial ischemiareperfusion injury in rats...
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Báo cáo khoa học:

Báo cáo khoa học: " Influence of ascorbic acid on BUN, creatinine, resistive index in canine renal ischemia-reperfusion injury" pps

Báo cáo khoa học

... tnereffid tnacifingis ton erew ,noitcnuf yendik fo xedni na sa derusaem ,slevel rC mureS stnemirepxe eht gnirud aimeru fo sngis lacinilc on dah spuorg htob fo sgod llA stluseR tnacifingis yllacitsitats ... detartsnomed erew slevel rC ni segnahc tnacifingis on ,M adaraH ,M awakayaH ,K arumukO ,H ianasO 3101-7001 ,58 ,0002 tnI UJB edixo cirtin fo elor eht :gninoitidnocerp cimehcsi laner yb yrujni noisufreper ... evitsiser fo tnemerusaem htiw )aeroK ,nosideM( yhpargonos relppoD roloC derusaem erew negortin aeru doolb dna eninitaerc mures dna ,)syad 41 ,7 ,5 ,3 ,1( slavretni emit tnereffid ta ylevitarepo-tsop...
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Báo cáo khoa học:

Báo cáo khoa học: "Attenuation of ischemia-reperfusion injury by ascorbic acid in the canine renal transplantation" pps

Báo cáo khoa học

... csavoidraC ecnaveler lacinilc dna ,smsinahcem ,snoitatsefinam :yrujni decudni noisufrepeR R illoB ,JD esraeH 01 216-506 ,243 ,0002 deM J lgnE N 6991 ot 8891 ,setatS detinU eht ni noitatnalpsnart ... erofeb nim 02 )aeroK ,mrahP naH iaD ;VI ,gk/g 1( lotinnam deretsinimda erew sgod ehT )VI ,h/gk/lm 01( noitulos etylortcele decnalab a deretsinimda erew sgod eht llA erudecorp eht gnirud ylppus ... selpmas eussit ehT ld/gm 8.1< ot dezilamron dah seulav eninitaerc mures eht fi keew tnalpsnart-tsop driht eht retfa seninac gnivivrus eht gnizinahtue rof dellac locotorp yduts ehT noitanimaxe lacigolohtapotsiH...
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Báo cáo y học:

Báo cáo y học: "Ischemic preconditioning reduces the severity of ischemia-reperfusion injury of peripheral nerve in rat" pptx

Báo cáo khoa học

... blunt injury to the abdominal aorta J Trauma -Injury Inferction and Critical Care 2003, 55:795-799 Murry CE, Jennings RB, Reimer KA: Preconditioning with ischemia: a delay of lethal cell injury in ... Discussion Nerve pathology in acute ischemic injury has beeen delineated in peripheral nerve and reperfusion injury could amplify ischemic pathology Nerve ischemia plays a major role in the development ... Plexus and Peripheral Nerve Injury 2006, 1:2 with reperfusion [6] An aggrevated reperfusion injury in Streptozocine induced diabetic rats could be seen with less severe ischemic times [7] Clinical...
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Báo cáo y học:

Báo cáo y học: "Beneficial effect of the oxygen free radical scavenger amifostine (WR-2721) on spinal cord ischemia/reperfusion injury in rabbits" docx

Báo cáo khoa học

... of spinal cord injury: Pharmacologic management of spine injuries In Lin Spinal Cord Medicine Principles and Practice Edited by: W V, Cardenas DD Demos Medical Publishing LLC; 2003:114 Tsujino ... Chatzimichalis A, Fotopoulos V, Kokkinis K, Papadimitriou E, Tiniakos D, Marinos E, Bellenis I, Dougenis D: In Situ Cooling in a Lung Hilar Clamping Model of Ischemia- Reperfusion Injury Exp Biol Med (Maywood) ... receptor-activated and subsequently mediated pathways, initiates chain reactions and damage cellular macromolecule, including proteins, DNA and lipids, ultimately leading to cell death [6] Eighteen New Zealand...
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Báo cáo y học:

Báo cáo y học: " Anti-inflammatory treatment strategies for ischemia/reperfusion injury in transplantation" ppt

Báo cáo khoa học

... the zink finger protein A20 as it combines anti-apoptotic as well as anti-inflammatory effects [61] It has ubiquitinating and de-ubiquitinating properties, thus, activating and/ or inhibiting target ... Long-term effects of acute ischemia and reperfusion injury Kidney Int 2004, 66:523-527 Kosieradzki M, Rowinski W: Ischemia/ reperfusion injury in kidney transplantation: mechanisms and prevention Transplant ... is a serine-threonine protein kinase activated through the phosphatidylinositol 3-kinase (PI3-kinase) pathway counteracting apoptosis [67] Expression and activation of SGK1 are increased in various...
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Báo cáo y học:

Báo cáo y học: " tài: Anti-inflammatory treatment strategies for ischemia/reperfusion injury in transplantation" potx

Báo cáo khoa học

... the zink finger protein A20 as it combines anti-apoptotic as well as anti-inflammatory effects [61] It has ubiquitinating and de-ubiquitinating properties, thus, activating and/ or inhibiting target ... Long-term effects of acute ischemia and reperfusion injury Kidney Int 2004, 66:523-527 Kosieradzki M, Rowinski W: Ischemia/ reperfusion injury in kidney transplantation: mechanisms and prevention Transplant ... is a serine-threonine protein kinase activated through the phosphatidylinositol 3-kinase (PI3-kinase) pathway counteracting apoptosis [67] Expression and activation of SGK1 are increased in various...
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Báo cáo y học:

Báo cáo y học: "The role of mast cells and fibre type in ischaemia reperfusion injury of murine skeletal muscles" pot

Báo cáo khoa học

... IR injury, thus proving that mast cells play a pivotal role in IR injury to skeletal muscle [5] Our IR injury model consists of 70 minutes tourniquet hind limb ischaemia followed by 24 h reperfusion ... fixed for 24 h in 10% BFS, washed in 0.1 M phosphate buffered saline (PBS) and processed into paraffin Five micron sections were cut, dewaxed and stained with Haematoxylin and Eosin (H&E) for general ... http://www.journal-inflammation.com/content/1/1/2 Figure Gastrocnemius muscle stained with Haematoxylin and Eosin Gastrocnemius muscle stained with Haematoxylin and Eosin Control (A & C) and IR treated hind...
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Báo cáo y học:

Báo cáo y học: "Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts" pps

Báo cáo khoa học

... Medicine, Chennai, India They were fed on commercial rat chow (Hindustan Lever, India) and had free access to water Handling of the animals was approved by the Indian Ministry of Social Justices and ... extract was determined by administering the rats with Desmodium gangeticum orally for 30 days and then sacrificing them for reperfusion- induced ischemic injury Lipid peroxidation in drug treated ... root induces myocardial protection against ischemia reperfusion injury in isolated rat hearts, as indicated by the improved recovery of cardiac function, reduction in cardiac enzyme release in...
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Role of cyclic AMP signalling mechanisms in heart protection against ischemia   reperfusion injury

Role of cyclic AMP signalling mechanisms in heart protection against ischemia reperfusion injury

Tổng hợp

... (adenosine) results in an extraordinary cardioprotective effect during normothermic (37°C) ischaemia and reperfusion Khaliulin I et al Cardiovasc Res 2010;88:324-33 Initial rate of swelling A520.105 ... depletes glycogen in myocardium This promotes binding of Hexokinase II to the mitochondrial membrane and inhibition of mitochondria permeability transition pore (MPTP) opening Cyclic AMP-induced activation ... both PKA and Epac effectively protects heart against ishaemia /reperfusion injury PKA and Epac act synergicaly in the cardioprotective effect of cAMP Scheme of Signal Transduction of the cAMPInduced...
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Báo cáo y học:

Báo cáo y học: " Role of dopamine D2 receptors in ischemia/ reperfusion induced apoptosis of cultured neonatal rat cardiomyocytes" potx

Báo cáo khoa học

... cerebral ischemia/ reperfusion injury [7] However, the role of dopamine D2 receptors on myocardial ischemia/ reperfusion injury has not been clear In this study, we applied myocardial ischemia/ reperfusion ... or incubated in simulated ischemia solution and re-incubated in DMEM in the presence or absence of 10 μM bromocriptine or haloperidol, respectively (B) Changes in fluorescent intensities of intracellular ... chromatin, and mitochondria structure was intact in the control group Morphological change of apoptosis, including nuclear pycnosis, nuclear chromatin margination, aggregation and condensation, and...
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Báo cáo y học:

Báo cáo y học: " Protection from pulmonary ischemia-reperfusion injury by adenosine A2A receptor activation" pdf

Báo cáo khoa học

... while still maintaining ischemia Atelectasis and reexpansion has been shown to induce injury involving edema, free radical generation, and apoptosis [33,34] This reexpansion-induced injury could ... of ischemia- reperfusion injury of rat lung Am J Pathol 1997, 150:1773-1784 Eppinger MJ, Jones ML, Deeb GM, Bolling SF, Ward PA: Pattern of injury and the role of neutrophils in reperfusion injury ... populations including alveolar macrophages, type II epithelial cells and neutrophils in the progression of IR injury Our findings suggest that cytokines and chemokines, such as TNF-α, KC and MIP-2,...
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Báo cáo y học:

Báo cáo y học: "A quality assessment of genetic association studies supporting susceptibility and outcome in acute lung injury" doc

Báo cáo khoa học

... Hernandez-Lopez J, Rodriguez-Gallego C: Mannose-binding lectin and mannose-binding lectinassociated serine protease in susceptibility, severity, and outcome of pneumonia in adults J Allergy Clin ... pneumonia; CXCL2, chemokine CXC motif ligand 2; F5, coagulation factor V; IL-6, interleukin-6; IL-10, interleukin-10; MBL2, mannose-binding lectin-2; MIF, macrophage migration inhibitory factor; MV, ... determining susceptibility and outcome in ALI or ARDS still needs to grow and continue improving for the identification of true associations between genotype and clinical outcomes important in the...
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Hydrogen sulfide produces cardioprotective effects against ischemia reperfusion injury via regulation of intracelluar PH

Hydrogen sulfide produces cardioprotective effects against ischemia reperfusion injury via regulation of intracelluar PH

Cao đẳng - Đại học

... subjected to ischemia (30 min) /reperfusion (10 min), suggesting that like the NHE-1 inhibitor, NaHS may also protect cardiac myocytes against ischemia/ reperfusion- induced injury We further examined the ... oxide OxyHb Oxyhemoglobin PGE2 Prostaglandin E2 pHi Intracellular pH xii    PI3K Phosphoinositol-3-kinase PKC Protein kinase C PKG Protein kinase G RAS Renin–angiotensin system RSH Thiol SO Sulfite ... protect hearts against ischemia/ reperfusion- induced injury (Karmazyn 2001), we further tested whether NaHS could also protect the cardiac myocytes against ischemia/ reperfusion injury The experimental...
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