nitrate nitrite and ischemia reperfusion injury
Báo cáo sinh học: "Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction" ppt
... groups and 3, and significantly lower in group than in group at 24 h and 72 h after IR injury On the other hand, this protein expression was markedly lower in group than in groups and 3, and notably ... expressions of NQO1, GR, and GPx, three anti-oxidative indicators, were remarkably lower in group than in groups and 3, and notably lower in Figure Histopathological scoring of ischemia- reperfusion (IR)-induced ... elicited by IR injury and ADMSC treatment contributed to further anti-inflammatory and anti-oxidative effects after IR-induced renal injury in this study Findings from Immunofluorescent and IHC Staining...
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Báo cáo sinh học: "The combined transduction of copper, zincsuperoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury" ppt
... Transduction of PEP-1-SOD1 and/ or PEP-1-CAT in rat myocardium and ischemia- reperfusion injury To observe whether transduced PEP-1-SOD1 and PEP-1CAT protect myocardial ischemia- reperfusion injury in Page ... tranduced into myocardium and protected against myocardial ischemiareperfusion injury in rats [12,14] To examine the combined effect of PEP-1-SOD1 and PEP-1-CAT, we applied both of PEP-1-SOD1 and ... myocardial ischemia- reperfusion injury CK CK-MB and cTnT are widely present in the cytoplasm of myocardial cells, and elevation of serum CK, CK-MB and cTnT are reliable indicators of myocardium injury...
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Báo cáo y học: "Ipsilateral common iliac artery plus femoral artery clamping for inducing sciatic nerve ischemia/reperfusion injury in rats: a reliable and simple method" doc
... method for sciatic nerve ischemia- reperfusion injury Microsurg 2007, 27(3):206-207 Iida H, Schmelzer JD, Schmeichel AN, et al.: Peripheral nerve ischemia: reperfusion injury and fiber degeneration ... of peripheral nerve of rats from ischaemia -reperfusion injury Brain 1999, 122(Pt 1):161-169 Saray A, Can B, Akbiyik F, et al.: Ischemia- Reperfusion injury of the peripheral nerve: an experimental ... randomly divided into six groups: one control group and five I/R groups at different time intervals of reperfusions (0 h, h, d, d, d) All animals were anesthetized with ketamine (50 mg/kg) and...
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Báo cáo y học: "CXC-chemokine regulation and neutrophil trafficking in hepatic ischemia-reperfusion injury in P-selectin/ICAM-1 deficient mice" docx
... liver injury following hepatic ischemia/ reperfusion in the rat Hepatology 1996, 23:506 Jaeschke H, Farhood A: Neutrophil and Kupffer cell-induced oxidant stress and ischemia- reperfusion injury ... subjected to 90 minutes of ischemia followed by and 15 h of reperfusion respectively; (D and F) P/I null mouse subjected to 90 minutes of ischemia followed by and 15 h of reperfusion, respectively ... null and wild-type mice were subjected to 90 minutes of warm liver ischemia followed by various periods of reperfusion Hepatic I/R caused significant hepatocellular injury at and 15 h of reperfusion...
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Báo cáo y học: "Low-dose vasopressin infusion results in increased mortality and cardiac dysfunction following ischemia-reperfusion injury in mice" potx
... point in each group were studied Ischemia- reperfusion of the LAD An open-chest model of I/R using ligation and reperfusion of the LAD was modified from Michael and colleagues [36] Mice were anesthetized ... 63.48 ± 2.9%, and 65.47 ± 2.4% in arginine vasopressin (AVP; n = 14), normal saline solution (SL; n = 9), and dobutamine (DOB; n = 6), resepctively Following ischemia/ reperfusion (I/R) injury, AVP ... Ballantyne CM: Myocardial ischemia and reperfusion: a murine model Am J Physiol 1995, 269:H2147-2154 37 Landry DW, Levin HR, Gallant EM, Ashton RC Jr, Seo S, D'Alessandro D, Oz MC, Oliver JA:...
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Báo cáo y học: "Ischemic preconditioning reduces the severity of ischemia-reperfusion injury of peripheral nerve in rat" pptx
... short ischemia with minute's intervals), and then hours of ischemia with hours of reperfusion Part 2: Long time effetcs of I/R and IP Group 1- I/R with long duration (7dR):4 hours of ischemia and ... McMarron PD: Reperfusion nerve injury pathology due to reflow and prolonged ischemia J Peripher Nerv Syst 1997, 2(1):60-69 Carden DL, Granger DN: Pathophysiology of ischemia- reperfusion injury J ... Journal of Brachial Plexus and Peripheral Nerve Injury 2006, 1:2 with reperfusion [6] An aggrevated reperfusion injury in Streptozocine induced diabetic rats could be...
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Báo cáo y học: "Beneficial effect of the oxygen free radical scavenger amifostine (WR-2721) on spinal cord ischemia/reperfusion injury in rabbits" docx
... Diazoxide, Prevents Ischemia- Reperfusion Injury in the Rabbit Cord Am J Pathol 2006, 168:1443-1451 Pacher P, Beckman SJ, Liaudet L: Nitric Oxide and Peroxynitrite in Health and Disease Physiol ... (Ca-1) and at the end of the experiment (Ca-8) It's noticed a decrease in Ca levels of 5.5% and 8% in (I) and (II) groups and 25% in (III) (animals 13 to 18) with antimutagenic, anticlastogenic and ... measured at excitation 535 and emission 550 nm against butanol-treated sample and reagent blanks (0.15 ml sample plus 0.15 ml 20% TCA containing 0.33 N HCl and 0.02% w/v BHA, and 0.15 ml homogenate-buffer...
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Báo cáo y học: " Anti-inflammatory treatment strategies for ischemia/reperfusion injury in transplantation" ppt
... Long-term effects of acute ischemia and reperfusion injury Kidney Int 2004, 66:523-527 Kosieradzki M, Rowinski W: Ischemia/ reperfusion injury in kidney transplantation: mechanisms and prevention Transplant ... chemoattractant protein-1 prevents renal ischemia- reperfusion injury J Am Soc Nephrol 2003, 14:1066-1071 Wanderer AA: Ischemic -reperfusion syndromes: biochemical and immunologic rationale for IL-1 ... interaction between ischemia- reperfusion and immune responses in the kidney J Mol Med 2009, 87:859-864 Diepenhorst GM, van Gulik TM, Hack CE: Complement-mediated ischemia- reperfusion injury: lessons...
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Báo cáo y học: " tài: Anti-inflammatory treatment strategies for ischemia/reperfusion injury in transplantation" potx
... Long-term effects of acute ischemia and reperfusion injury Kidney Int 2004, 66:523-527 Kosieradzki M, Rowinski W: Ischemia/ reperfusion injury in kidney transplantation: mechanisms and prevention Transplant ... chemoattractant protein-1 prevents renal ischemia- reperfusion injury J Am Soc Nephrol 2003, 14:1066-1071 Wanderer AA: Ischemic -reperfusion syndromes: biochemical and immunologic rationale for IL-1 ... interaction between ischemia- reperfusion and immune responses in the kidney J Mol Med 2009, 87:859-864 Diepenhorst GM, van Gulik TM, Hack CE: Complement-mediated ischemia- reperfusion injury: lessons...
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Báo cáo y học: " Protection from pulmonary ischemia-reperfusion injury by adenosine A2A receptor activation" pdf
... the development of lung ischemia- reperfusion injury J Thorac Cardiovasc Surg 2003, 126:200-207 Day YJ, Huang L, Ye H, Linden J, Okusa MD: Renal ischemia- reperfusion injury and adenosine 2A receptor-mediated ... and drafted the manuscript JL and ILK helped with the analysis and interpretation of the data VEL helped in conception and design of the experiments, analysis and interpretation of the data and ... dysfunction from pulmonary ischemia- reperfusion injury Ann Thorac Surg 2005, 79:1189-1195 Rivo J, Zeira E, Galun E, Einav S, Linden J, Matot I: Attenuation of reperfusion lung injury and apoptosis by A2A...
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Báo cáo y học: "Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts" pps
... diazotization of nitrite with sulphanilamide and subsequent coupling with napthylethylenediamine was read at 546 nm and referred to the absorbance of standard solutions of potassium nitrite also ... gangeticum orally for 30 days and then sacrificing them for reperfusion- induced ischemic injury Lipid peroxidation in drug treated rat hearts were reduced as compared to ischemia reperfusion control hearts ... factors for myocardial ischemia reperfusion injury [6] Xanthine dehydrogenase, which normally utilizes NADH as an electron acceptor, is converted under the conditions of ischemia/ reperfusion into xanthine...
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Role of cyclic AMP signalling mechanisms in heart protection against ischemia reperfusion injury
... Coronary Artery Occlusion and Heart Attack Heart Attack Myocardium Atheroslcerosis Reperfusion Thrombosis Risk Zone IschaemiaReperfusion INJURY Experimental Protocol C IP TP SHP ... cyclic AMP analogue 8Br-cAMP-AM which activates both PKA and Epac effectively protects heart against ishaemia /reperfusion injury PKA and Epac act synergicaly in the cardioprotective effect of ... ROS PKC Acknowledgements Doctor Andrew James Doctor Mark Bond Professor Saadeh Suleiman Professor Andrew P Halestrap Labs of Professor Saadeh Suleiman and Professor Andrew Halestrap ...
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Hydrogen sulfide produces cardioprotective effects against ischemia reperfusion injury via regulation of intracelluar PH
... myocytes injury induced by ischemia and reperfusion for 10, 30, and 60 D, treatment with NaHS (100 μM) and KR (KR-32568; μM) alone or a combination of both protected myocytes against ischemia/ reperfusion ... preischemia value at the first 15 of reperfusion These data indicate that NaHS treatment significantly restored the contractility and compliance of hearts subjected to ischemia/ reperfusion injury ... protect hearts against ischemia/ reperfusion- induced injury (Karmazyn 2001), we further tested whether NaHS could also protect the cardiac myocytes against ischemia/ reperfusion injury The experimental...
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Báo cáo y học: "Gadolinium decreases inflammation related to myocardial ischemia and reperfusion injury" pdf
... myocardium or serum during ischemia and reperfusion Rats were either treated with vehicle or GdCl3 either before 30 ischemia and 120 reperfusion or a Sham procedure (Ischemia) and (Reperfusion) in the ... correlates with Ischemia and Reperfusion in the Control and GdCl3 groups IL-8/CINC-1 was measured from the serum at 30 ischemia and 120 reperfusion and from the tissue at 120 reperfusion A) Quantitation ... after ischemia and reperfusion [1] * 3000 * * 2500 2000 * * * * * 1500 1000 500 Control GdCl GdCl Control Ischemia- Reperfusion (Reperfusion) Sham 3500 (Ischemia) GdCl3 B GdCl3 Sham Perfusion Ischemia- Reperfusion...
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Báo cáo y học: "Cellular infiltrates and injury evaluation in a rat model of warm pulmonary ischemia–reperfusion" pot
... macrophages and neutrophils after hour of ischemia and hours of reperfusion • Significant late increase of neutrophils after hour of ischemia and hours of reperfusion • Significant apoptosis and lung ... in ischemia reperfusion injury remains unclear Qayumi and colleagues concluded that upregulation of MHC II on peripheral lymphocytes is related to the degree of damage caused by ischemia reperfusion ... pulmonary ischemia reperfusion in a human lung transplantation study [13] In summary, little is known about the role of neutrophils, T cells and macrophages in ischemia reperfusion injury In...
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Báo cáo y học: "Emulsified Isoflurane Preconditioning Reduces Lung Injury Induced By Hepatic Ischemia/Reperfusion in Rats"
... lipopolysaccharide induced acute lung injury in rats Inflamm Res 2005; 54: 133-137 Hato S, Urakami A, Yamano T et al Attenuation of liver and lung injury after hepatic ischemia and reperfusion by a cytokine-suppressive ... to ischemia- reperfusion injury J Neurol Sci 2006; 247: 47-52 35 Yoshidome H, Kato A, Edwards MJ et al Interleukin-10 inhibits pulmonary NF-kappaB activation and lung injury induced by hepatic ischemia- reperfusion ... neutrophil-dependent lung and liver injury associated with hepatic ischemia and reperfusion in the rat Shock 1998; 10: 182-91 37 Zhong C, Zhou Y, Liu H Nuclear factor kappaB and anesthetic preconditioning...
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