... splicing enhancers and silencers, which function as activators and repressors of the splicing mechanism, respectively These can occur in exons as exonic splicing enhancers (ESEs) or silencers ... element; LTR: long terminal repeat; MS: mammalian specific; PS: primate specific; ROC: receiver operating characteristic; SINE: short interspersed nuclear element; SRE: splicing regulatory element; ... of sequences that can function as splicing cis-regulatory elements, and their positionspecific effects This raises the question of whether the low inclusion observed for species-specific exons...
... Nations CIETAC China International Economic and Trade Arbitration Commission Council Regulation European Council Regulation No 44/2001 of 22 December 2000 on 44/2001 in Europe jurisdiction and ... RULES European Council Regulation No 44/2001 of 22 December 2000 on jurisdiction and the recognition and enforcement of judgments in civil and commercial matters ICSID Rules of Procedures of Arbitration ... including its existence17 This provision is included in almost arbitration rules, e.g., of ICDR, ICSID, LCIA, WIPO, CIETAC, JCAA, UNCITRAL, etc The main reason of this obligation is to protect...
... severe cartilage lesions, less synovitis, significant reduction in the size of osteophytes, and significant improvement in clinical indicators of pain and disease activity A first randomized controlled ... not for citation purposes) Caron JP, Fernandes JC, Martel-Pelletier J, Tardif G, Mineau F, Geng C, Pelletier JP: Chondroprotective effect of intra-articular injections of interleukin-1 receptor ... because the profile of cytokine production in human IVDs looks like the one observed in OA and because resident cells from discs behave like chondrocyte cells Some evidence suggests that IL-1β...
... tri n c n ph i c kh n ng cung c p s li u c b n cho vi c xây d ng k ho ch phát tri n kinh t b o v môi tr ng â y th c s m t n i dung lý thuy t n c phát tri n nh ng ch a c b ng ch ng c th cho s ... t n c ang phát tri n, h th ng th ch c ng nh s an xen gi a c u tr c xã h i nên c n h n h t m t c ch nhìn toàn c nh, x c t c ng c a kinh t xã h i lên phát tri n LIS Do ó h th ng LIS cho n c ang ... tr t ch c tài ã h tr n c ang phát tri n xây d ng h th ng nh v y Cc n c ang phát tri n c ng r t mong mu n cc m t h th ng t ng t Cc d án phát tri n h th ng LIS nêu trên, thông th ng chép l...
... calibrating small pipettes manufactured in the laboratory Such a set should comprise, at least, pipettes delivering 10 c. c., c. c., 2.5 c. c., c. c., c. c., 0.5 c. c., 0.25 c. c., 0.2 c. c., 0.1 c. c., ... found especially useful—viz., cm diameter by cm high, capacity about 14 c. c.; and cm diameter by cm high, capacity about 25 c. c These are stored in copper cylinders of similar construction to ... of Application, 27—Electric Signal Timing Clock, 38 IV THE MICROSCOPE 49 Essentials, 49—Accessories, 57—Methods of Micrometry, 61 V MICROSCOPICAL EXAMINATION OF BACTERIA AND OTHER MICRO-FUNGI...
... eFFectIve PRogRaMs tHat tacKle tHe Root causes oF HoMelessness, cRIMe, and otHeR dIsaBlIng econoMIc and socIal condItIons SoCIAl FINANCE, INC Q ThE world’S FIrST SoCIAl IMPACT BoNd social Finance ... bear on social problems Unlike public-sector or grant funding, impact investments produce financial returns that can be reinvested in the social sector In this way, capital can be recycled and ... aging-in-place via supportive housing Reduced nursing home stays u Medicaid SoCIAl FINANCE, INC u corrections u Housing services u corrections, Probation, & Parole u Medicare ChroNICAlly hoMElESS...
... Hopfer (Case Western Reserve University, Cleveland, OH, USA) The human colon carcinoma cell line Caco-2 was obtained from the German Collection of Microorganisms and Cell Cultures (Braunschweig, ... Hills’ coefficient Inhibition constants (Ki) were calculated from IC50 values Acknowledgements This work was supported by the State Saxony-Anhalt Life Sciences Excellence Cluster (MB) References ... trans conformers, according to the chromatograms Radioactive purity of the final product was > 98% according to TLC [silicagel 60 F254 plate, Merck, Darmstadt, Germany; solvent system n-butanol-acetic...
... arbiwhere DCT ¼ DCT trary unit (AU) corresponds to the expression of b-actin Indirect immunofluorescence and confocal microscopy HEK293 cells were cultured on coverslips and transiently transfected ... speci c antibodies followed by the appropriate anti-IgG–peroxidase conjugate Blots were developed by the enhanced chemiluminescence technique (ECL kit; GE Healthcare) according to the manufacturer’s ... the C- terminus of KCTD5 [16] changes its location to the nucleus, cells were transfected with different deletion mutants of KCTD5 Immunocytochemistry of these cells showed that these constructs...
... Sequence analysis (A) Domain composition of Mycobacterium tuberculosis Rv0386 (B) Local alignment of Rv0386 with the noncanonical class IIIc AC Rv190 0c, the canonical class IIIc AC Rv1264 and the canonical ... mycobacterial ACs have been investigated (class IIIa: AC Rv162 5c; class IIIb: Rv131 8c, Rv131 9c, Rv132 0c, Rv3645; class IIIc: Rv1264, Rv1647) [8,16–19] Of the noncanonical CHDs only Rv190 0c (class ... available structural data of canonical mammalian class IIIa and mycobacterial class IIIc catalytic domains [5,7,9,25] nor they parallel the findings on the noncanonical class IIIc AC Rv190 0c [14] Another...
... frequency HMMbased posterior was shown to be better than treating each occurrence as count one Once we have computed all feature values for all phrase pairs in the training corpus, we discriminatively ... perfect combination of feature functions divides the correct and incorrect candidate phrase pairs within a parallel sentence into two ordered separate sets We use feature functions to decide ... In Proc of EMNLP-CoNLL, pages 967– 975 P Koehn, F Och, and D Marcu 2003 Statistical phrasebased translation In Proc of HLT-NAACL, pages 48– 54 D Lin 1999 Automatic identification of noncompositional...
... reflected in higher credit costs in the 1980s With seemingly inelastic demand for credit, higher prices did not affect the amount of credit demanded as much as expected What Caused the Inelasticity ... loans decreased significantly, credit card rates remained close to their highs of the early 1980s, seemingly impervious to market forces Credit Cards Are No Different The credit cards that seemed ... non-interest charges such as fees to compensate for interest rate ceilings, they effectively raise the cost of credit for all successful borrowers Therefore, while a ceiling may reduce the explicit price...
... subject Many influences affect our brands Many can be analyzed and explained Many cannot Cause and effect are certain only in pure science Branding is a science in the way social science is a science, ... strategic branding process, often undertaken with the assistance of advisers, coaches, and other mentors who propelled their achievements and celebrity How to achieve success is a key theme in ... helped him fend off his chief opponent, the corrupt aristocrat Lucius Sergius Catilina The branding campaign worked Marcus Cicero was elected consul in a landslide in 64 B .C Is Personal Branding...
... in T cells, binds RNA NM_012218 35 NM_173798 Nucleic acid binding, transcriptional regulation CCHC zinc finger domain (zinc-knuckle) double-stranded RNA-binding motifs (DSRM), C- terminal glycine-rich ... transfected in Saccharomyces cerevisiae strain L40 A human fetal brain cDNA library (Clontech, Palo Alto, CA) expressing GAL4 activation domain (AD) fusion proteins was cotransfected with each one ... R Camargo for technical assistance, Dr Schwab U, Stein H, Gerdes J, Lemke H, Kirchner H, Schaadt M & Diehl V (1982) Production of a monoclonal antibody speci c for Hodgin and Sternberg–Reed cells...
... of mobile phase A (acetonitrile ⁄ water ⁄ acetic acid ⁄ trifluoroacetic acid; : 98 : 0.1 : 0.02; v ⁄ v ⁄ v ⁄ v) and B (acetonitrile ⁄ water ⁄ acetic acid ⁄ trifluoroacetic acid; 10 : 90 : 0.009 ... Steady-state kinetics Scheme (A) Random-order ternary-complex mechanism, (B) compulsory-order ternary-complex mechanism (ATF2D115 binds first, ATP second), (C) Compulsory-order ternary-complex mechanism ... Szafranska and K N Dalby CA) electrospray, ion trap mass spectrometer coupled with a Magic 2002 Microbore HPLC (Microchrom BioResource, Auburn, CA) The mass spectrometer was scanned over a 300–2000 m...
... replace Ser274 in ik3-1 cDNA with Thr or Ala, mutagenic primers, 50 -TCTCCGGAGATGTCGAACACT CTCAGGTACTCCCAGACCA-30 or 50 -TCTCCGGAGAT GTCGAACACTCTCAGGTGCTCCCAGACCA-30 (corresponding to amino-acid ... by cyclin A/cdk2, cyclin E/cdk2, cyclin A/cdk3 or cyclin E/cdk3 which is produced in the baculoviral system We initially tested a hypothesis that p70ik3-1 might be a regulatory cyclin for p35cdk3 ... coexpressed either cyclin A or cyclin E in association with either cdk2 or cdk3 baculovirally in insect cells (Fig 1A, lanes 6–9 of each panel) In parallel, we expressed each cyclin or each cdk...
... Resources 94 Acronyms Used In This Report: ADG ARRA CCEF CHP CO2 DLA DoD DoE DoT ERDC-CERL FAA ITC kW kWh MCFC MW MWh NYSERDA PAFC PEM SGIP SOFC sq ft Anaerobic digester gas American Recovery ... Download the Commercially Available Fuel Cell Product List on the U.S Fuel Cell Council‘s website: http://www.usfcc.com/resources/outreachproducts.html Source: Fuel Cell Today In September 2009, ... a technical partnership to conduct a fuel cell vehicle testing program Zero-emission fuel cell powered package delivery vehicles were placed in daily commercial service, the first such demonstration...
... proline-rich proteins (SPRs) Such concerted reactions result in formation of the cornified envelope (CE), a specialized component consisting of covalent crosslinks of proteins beneath the plasma membrane ... speci c colorimetric assay for the measurement of TGase cross-linking activity Anal Biochem 389, 150–156 33 Hitomi K, Kitamura M, Alea MP, Ceylan I, Thomas V & El Alaoui S (2009) A speci c colorimetric ... when FITC–pepK5 and FITC–pepE51 were used According to the FITC–pepE51 pattern, the activated TGase was mainly located in the medulla and the hair cortex However, according to the FITC–pepK5...
... PART ONE Feedback from the local workforce can be a way to identify emerging issues and concerns of local communities ✔ Recognize employees as a good channel of communication Local communities tend ... channel of communications as a means of outreach and dissemination to the local population Feedback from the local workforce can also be a way to identify emerging issues and concerns of local communities ... relations can become politicized and complicated, and can lead to or exacerbate conflicts and other unanticipated outcomes There is no easy formula for addressing these challenges, except to try...