neuroendocrine regulation of cancer progression i biological mechanisms and clinical relevance
Is there information in financial analysts forecasts about firms that subsequently restate their earnings
... risk characteristics, such as beta, marketability, firm size, and earnings growth variability They find a positive and significant association between forecast dispersion and the traditional market-based ... hard to distinguish between intentional manipulation and unintentional misinterpretation in some cases AICPA Professional Standards, AU @ 420.15 (American Institute of Certified Public Accountants ... and dividend growth of the firm as a risk variable, and he compares this risk variable with other risk variables such as beta, inflation risk, interest rate risk, and economic activity risk with...
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Tài liệu Báo cáo khoa học: "The Structure of User-Adviser Dialogues: Is there Method in their Madness?" pdf
... other hand, pronominal noun phrases play a role in indicating and realizing topic continuity in a dialogue Since new topics are introduced at the beginning of new subdialogues and developed in the ... representation and use of focus in dialogue understanding Technical Report 151, Artificial Intelligence Center, SRI International Grosz, B.J., Joshi, A.K., Weinstein, S 1983 Providing a Unified Account ... previous work in linguistics and psychology Because this analysis was performed independently of the dialogue segmentation and subordination, it is a converging analysis and it supports the derived...
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báo cáo hóa học:" CRP identifies homeostatic immune oscillations in cancer patients: a potential treatment targeting tool?" pdf
... with termination of the immune response, which is indicative of a regulated anti-tumour immune response in the cancer patient, in a homeostatic fashion, similarly to inflammation from infection ... Oscillation and Other Diseases Further clinical evidence for homeostatic immune oscillations is found in autoimmunity, especially associated with lymphodepletion or immunotherapy (eg thyroiditis ... 14(3):710-4 Williams DK, Muddiman C: Absolute Quantification of C-Reactive Protein in Human Plasma Derived from Patients with Epithelial Ovarian Cancer Utilizing Protein Cleavage Isotope Dilution Mass...
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báo cáo hóa học: " Quality of life data as prognostic indicators of survival in cancer patients: an overview of the literature from 1982 to 2008" pot
... of this line of research is that of potentially providing clinicians with a more accurate picture of the patient's prognostic profile, hence possibly further improving accuracy of prognosis and ... quality of life at baseline assessment may live longer Thus it is not surprising that, in addition to clinical measures, quality of life data are predictive of survival duration This hypothesis ... Bruning PF, Klijn JG, van Hoorebeeck I, Paridaens R: Identification and interpretation of clinical and quality of life prognostic factors for survival and response to treatment in firs-line chemotherapy...
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báo cáo hóa học:" Pain in cancer. An outcome research project to evaluate the epidemiology, the quality and the effects of pain treatment in cancer patients" pptx
... regions, as well as some "strong" WHO-step III opioids, making it difficult for physicians the appropriate prescription of drugs and creating variability in drugs utilization across different Italian ... aimed at making available to treating physicians, patients and families valid information about pain management in cancer Two main lines of activities were identified as necessary: information ... participating centers during the study inception period will be screened, and if considered eligible included, registered and monitored over time After a check of the eligibility and inclusion in...
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Báo cáo khoa học: "Ultrasound-guided central venous catheterization in cancer patients improves the success rate of cannulation and reduces mechanical complications: A prospective observational study of 1,978 consecutive catheterizations" pps
... efficacy of ultrasound-guided insertional CVC in patients with hematological and solid tumors, to confirm the utility of this procedure in clinical practice, and to evaluate local or systemic infection, ... symptomatic vein thrombosis of upper limbs (early or late), infections, malfunctioning and lifespan of the CVC Page of In cases of clinical suspicion of venous thrombosis evidenced by progressive ... mediastinum CVC dislocation in (0.1%), vein collapse in (0.48%) and no efficacious “eco window” in (0.1%) There were no differences in mechanical complications, malposition and malfunctioning of...
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Báo cáo khoa học: "Perioperative immune responses in cancer patients undergoing digestive surgeries" pptx
... post-operative severity of immunosuppressive sequelae and the patient's susceptibility to infectious complications However, it is difficult to predict the occurrence of postoperative complications ... Figure Changes5in Th1/Th2 ratio in surgical patients with malignancy from the viewpoint of postoperative complications Changes in Th1/Th2 ratio in surgical patients with malignancy from the viewpoint ... nature and risk of this study, and written informed consent was obtained The criteria for inclusion were major surgical tumor resection (digestive tract or liver cancers) and expected duration of...
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Báo cáo khoa học: " Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence" doc
... (AT) in 1988 AT is an inherited recessive disorder associated with neurological dysfunction, growth abnormalities, extreme radio-sensitivity, immunological deficiency and increased risk of malignancy ... binding domains, Leucine zipper, ATP-binding domains, FAT domain and PI3K domain [17] together with exonic information (The size of the exons and the distance between them are not indicative of ... the PI3K domain, substrate binding domains and ATPbinding domains, is illustrated in Figure Single marker associations Risk for developing breast cancer The association between any variant in the...
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báo cáo khoa học: "The potential benefits of low-molecular-weight heparins in cancer patients" ppsx
... prophylaxis in their cancer patients [52] Trials investigating thromboprophylaxis in medical patients hospitalized for acute medical illnesses have reported clinical benefits in terms of a significant ... the risk of VTE outweighs the risk of bleeding in most cancer patients [30,31], the use of antithrombotic agents which provide stable anticoagulation while minimizing bleeding complications is ... VTE in this high-risk population Prophylaxis in medical cancer inpatients There is a growing awareness of the risks of VTE in hospitalized medical patients Medical patients account for approximately...
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Báo cáo y học: "Is Phytalgic® a goldmine for osteoarthritis patients or is there something fishy about this nutraceutical? A summary of findings and risk-of-bias assessment" pot
... official organizations (for example, the National Institutes of Health, which indeed needs reshuffling of its priorities) These initial data on Phytalgic® would seem to justify such action If these ... Competing interests The funding agencies (The Oak Foundation and The Danish Rheumatism Association) had no role in writing the report or in the decision to submit the manuscript for publication Neither ... Pharmavie (Ivry-sur-Seine, France), Pfizer Inc (New York, NY, USA), Roche (Basel, Switzerland), sanofi-aventis (Paris, France), Scandinavian Clinical Nutrition (Stockholm, Sweden), and Wyeth (Madison,...
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Báo cáo khoa học: "Performance of six severity-of-illness scores in cancer patients requiring admission to the intensive care unit: a prospective observational study" pot
... SAPS II and APACHE II in 242 ICU cancer patients [17] In that study, the ability of SAPS II to discriminate between survivors and nonsurvivors (AUROC = 0.825) was superior to those of APACHE II ... to ICUs Although none of these models should be used to predict individual outcomes, they can assist physicians in discussions of prognosis and in clinical decision making to improve allocation ... hospital for referral of cancer patients in Rio de Janeiro, Brazil Its ICU is a 10bed medical/surgical unit exclusively for oncological patients, with full-time medical and nurse directors, and...
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Báo cáo y học: "Clinical review: Specific aspects of acute renal failure in cancer patients" pot
... complication of cytoreductive therapy and develops in 20% to 40% of BMT recipients [47] Amphotericin during conditioning Acyclovir during conditioning Vancomycin during conditioning The main site ... association with ARF and haemorrhagic cystitis [50] Finally, adenovirus is associated with disseminated infections, encephalitis, pneumonitis and ARF [51] To allow either a prompt reduction in immunosuppression ... sepsis and druginduced toxicity Prevention of ARF is mandatory in CICPs Fluid expansion and uricolytic treatment in patients with a high risk of acute TLS, prevention of contrast nephropathy, elimination...
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Báo cáo khoa học: "N-terminal pro-brain natriuretic peptide as an early prognostic factor in cancer patients developing septic shock" pdf
... cubic millimeter); infection category (clinically documented infection or microbiologically documented infection); severity -of- illness scores using Simplified Acute Physiology Score II at admission ... stay; and time from sepsis diagnosis to ICU admission and time from ICU admission to septic shock diagnosis and ICU mortality Early prognostic factors were defined as easy-to-collect, clinical and ... [14,41,44] In addition, patients considered to benefit significantly from immediate ICU admission were managed systematically and daily by both the intensivist and the hematologist/ oncologist until ICU...
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Báo cáo y học: " C-reactive protein in critically ill cancer patients with sepsis: influence of neutropenia" doc
... of the manuscript 15 Authors’ information PP is coordinator of the Polyvalent Intensive Care Unit and president of the Antibiotic Commission of São Francisco Xavier Hospital PP is Professor of ... and C-reactive protein At ICU admission, temperature in septic critically ill cancer patients was not significantly different in those presenting neutropenia in comparison with non-neutropenic ... started in all septic cancer patients upon ICU admission Page of according to to local guidelines and in accordance with the Infectious Diseases Society of America guidelines [2] The prescription...
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báo cáo khoa học: "Magnitude of risks and benefits of the addition of bevacizumab to chemotherapy for advanced breast cancer patients: Meta-regression analysis of randomized trials" ppt
... 3Department of Medical Oncology, University Hospital of Udine, Udine, Italy 4Biostatistics/ Scientific Direction, Regina Elena National Cancer Institute, Roma, Italy Institut Multidisciplinaire d’Oncologie, ... (definition of the question the analysis was designed to answer), definition of the trial selection criteria, definition of the search strategy, and a detailed description of the statistical ... metastatic breast cancer [32,33] in over 3,000 patients in three randomized trials showing a statistically significant increase in PFS, resulting in a reduced risk of progression of about 30% In the...
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The NR4A orphan nuclear receptors are target genes of the novel drug c1 in cancer cells and potential mediators of drug induced apoptosis
... Table of Contents ii Summary viii List of Figures ix List of tables xi Abbreviations xii List of publications xiv PART 1 INTRODUCTION Oncogenesis and the development of cancer therapies 2 Nuclear ... domain which has sufficient variation to allow for ligand selectivity and possesses a ligand induced activation function called AF2 which is important in transcriptional coregulator interactions ... transport and elimination (Chawla et al., 2001) RXRs are activated by dietary lipids like docosahexaenoic acid, phytanic acid which is a toxic plant lipid, and methoprene acid an insecticide derivative...
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The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis
... transcription factors, Inhibitor of differentiation (Id) proteins, of which Id2 is known to interact with pRb, p107 and p130, might be involved in the differentiation of PNECS, since Id2 and Id4 ... 2001) In summary, pRb is able to repress gene transcription by means of direct inhibition of the transcription machinery, direct binding and inhibition of E2F transactivation capacity or by recruiting ... accompanies pRb inactivation in vivo For example, conditional inactivation of Rb in the pituitary gland revealed that tumorigenesis is preceded by induction of apoptosis and proliferation (Vooijs...
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báo cáo khoa học: "Chemoradiotherapy followed by surgery versus surgery alone in esophageal cancer patients: is it time for additional evidence?" doc
... charges • Immediate publication on acceptance • Inclusion in PubMed, CAS, Scopus and Google Scholar • Research which is freely available for redistribution Submit your manuscript at www.biomedcentral.com/submit ... D, Mayer R: Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781 J Clin Oncol 2008, 26(7):1086-92 ... 5134 doi:10.1186/1477-7819-9-41 Cite this article as: Cafarotti et al.: Chemoradiotherapy followed by surgery versus surgery alone in esophageal cancer patients: is it time for additional evidence?...
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Báo cáo khoa học: "Postmastectomy irradiation in breast in breast cancer patients with T1-2 and 1-3 positive axillary lymph nodes: Is there a role for radiation therapy" ppsx
... 4.5 Primary tumor location Lata Lat Lat Medb Med Lat Histology IDCc IDC ILC IDC IPDd IDC Nuclear Grade II I II III II II Histologic Grade II I II II II I Receptor - + + + - - Lymphatic invasion ... give us better information the role of PMRT in this patient group [6] Radiation oncologists often confront patients with 1-3 positive lymph nodes following MRM in their routine clinical practice ... the role of PMRT for women with to positive lymph nodes remains uncertain and is being examined in a randomized clinical trial” Many surgeons and radiation oncologist are not recommending PMRT...
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báo cáo hóa học:" Comparative study on the immunogenicity between an HLA-A24-restricted cytotoxic T-cell epitope derived from survivin and that from its splice variant survivin-2B in oral cancer patients" pot
... and their cytotoxicity against survivin-positive cancer cell lines Induction Induction of survivin-C58 peptide-specific CTLs and their cytotoxicity against survivin-positive cancer cell lines CTLs ... splicing variants of human survivin have been described, including survivin-2α, survivin-2B, survivin-ΔEx3, and survivin-3B [12-15] While survivin-2α and survivin-3B are truncated forms, survivin2B ... Peptides and Cytokines Wild type survivin-derived peptides carrying HLA-A24 binding motif Survivin-C58 (amino acid sequence FFCFKELEGW), a splicing variant survivin-2B-derived peptide Survivin-2B80-88...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008