... 2008, 46:327-360 Park DW, Sohn JW, Cheong HJ, Kim WJ, Kim MJ, Kim JH, Shin C: Combination therapy of disseminated coccidioidomycosis with caspofungin and fluconazole BMC Infect Dis 2006, 6:26 ... aspergillosis, using voriconazole treatment Blood 2005, 106:2641-2645 Walsh TJ, Anaissie EJ, Denning DW, Herbrecht R, Kontoyiannis DP, Marr KA, Morrison VA, Segal BH, Steinbach WJ, Stevens DA, van Burik JA, ... doi:10.1186/cc9228 Cite this article as: Zhang M, et al.: Invasive pulmonary andcentralnervoussystem aspergillosis following slops aspiration in a trauma patient Critical Care 2010, 14:442 ...
... Several lines of in vitro evidence have pointed to a possible role for VEGF in lung repair and recovery following injury[19,29,35,36] In one LPSinduced murine model of lung injury, intrapulmonary ... depicting 3ng/ml and combination confirming a significant and cell number (B) following treatment for 48 hours with Bar Bar graphs depicting 3H-thymidine incorporation into ATII cells (A) and cell ... UK) in methanol (BDH Laboratory Supplies, Poole, UK) Sections were incubated in 2.5% horse blocking serum (Vectastain Universal Quick Kit, Vector Laboratories, Peterborough, UK) prior to Avidin...
... the supernatants were taken for scintillation counting Creatine kinase determination Creatine kinase activity was assayed following the method of Bernt and Bergmeyer [24], in the presence of fructose ... D.H., de Laat, S.W & van Wijk, R (1984) Analysis of K+ and Na+ transport and intracellular contents during and after heat shock and their role in protein synthesis in rat hepatoma cells Cancer ... (2 mM), sodium phosphocreatine (5 mM) and creatine kinase (EC 2.7.3.2, type from rabbit muscle) UÆlL)1 were added as an ATP-regenerating system to maintain membrane integrity [19] The lysed cell...
... Chemokines: leucocyte recruitment and activation cytokines Lancet 1997, 349:490-5 Glabinski AR, Ransohoff RM: Chemokines and chemokine receptors in CNS pathology J Neurovirol 1999, 5:3-12 Kunkel ... chemokines and chemokine receptors in the centralnervoussystem of multiple sclerosis patients J Clin Invest 1999, 103:807-15 Trebst C, Staugaitis SM, Tucky B, Wei T, Suzuki K, Aldape KD, Pardo ... expressed within inflammatory brain lesions in MS [18,39-41], and CCL3 has been demonstrated in cerebrospinal fluid of MS patients with relapsing-remitting disease course [42] In Interestingly and consistent...
... within strain pair wise comparison Bonferonni corrected t-test p < 0.05 Viral RNA and TLR mRNA expressionand demyelination analysis using in situ hybridization In order to detect the TMEV, a cDNA ... direct or indirect (by the induction of cytokines and chemokines) involvement of TLRs in the initiation of TMEV-IDD in C57BL/6 resistant mice following LPS stimulation The involvement of TLRs in the ... 173:3916-3924 Kerfoot SM, Long EM, Hickey MJ, Andonegui G, Lapointe BM, Zanardo RC, Bonder C, James WG, Robbins SM, Kubes P: TLR4 contributes to disease-inducing mechanisms resulting incentralnervous system...
... miRNAs1expressed in proliferating and/ or differentiating cells in the developing and adult zebrafish brain miRNAs expressed in proliferating and/ or differentiating cells in the developing and ... 20, and Table D in Additional data file 27) In contrast, miR-34 expression is absent from forebrain and midbrain and present only in the caudal ventral and lateral isthmus and hindbrain, including ... H, Fukushima T: Expression profile analysis of microRNA (miRNA) in mouse centralnervoussystem using a new miRNA detection system that examines hybridization signals at every step of washing...
... iNOS in neutrophils and macrophages and by brain cells may play an important role 80 Taekyun Shin et al in eliminating Listeria monocytogenes as well as in the destruction of brain tissue Acknowledgments ... staining of inducible NOS in the caprine brain with natural listeriosis shows that iNOS immunoreactivity was recognized in neurons, some inflammatory cells in perivascular cuffings Counterstained ... NOS expressionin the goat brain with listeriosis The involvement of iNOS in bovine and caprine listeriosis has been reported previously, and the increased expression of iNOS and the resultant...
... Radin DR, Chandrasoma P: Merkel cell carcinoma J Comput Tomogr 1987, 11(3):291-293 Toker C: Trabecular carcinoma of the skin Arch Dermatol 1972, 105(1):107-110 Ikawa F, Kiya K, Uozumi T, Yuki K, ... the patient to start using a wheelchair On examination, lower limb weakness, hyporeflexia and a positive Babinski sign were found Emergency MRI of the spine and the spinal canal showed that the ... http://www.jmedicalcasereports.com/content/5/1/35 Page of Table Intraspinal metastases of Merkel cell carcinoma reported in the literature Year Age/gender Other metastasis Intraspinal involvement Level Time since detection Survival...
... interacting complex, MKK-4 (MAP kinase kinase) and JNK-1 (Jun kinase) are also required for maintaining normal synaptic structure [69,70] These findings suggest that additional proteins in this subcluster ... binding For example, the JIP3/JSAP1 JNK scaffolding protein, UNC-16, interacts with KLC-2 (kinesin light chain) to regulate vesicular transport in neurons [68] Other members of this interacting ... (MKK-4) B0547.1 F35C8.3 (JKK-1) ZK1098.10 (UNC-16) K1 1E8.1 (UNC-43) C18C4.10 (KLC-2) Y54E10BL.6 R03G5.2 (SEK-1) F59A6.1 (NSY-1) F13B9.5 (KSR-1) Nucleic acid binding Synaptic function No known expression/ function...
... genes in the Wnt signaling pathway were prominently affected by aging and CR in several CNS regions in our study, including those encoding nemo-like kinase, α-catenin and calcium/calmodulindependent ... factor; Tab1, TGF-beta activated kinase-1 binding protein-1; Tak1, TGF-beta-activated kinase Right: Werner (WRN) interacting proteins involved in DNA repair and telomere homeostasis PARP-1, poly ... aging (Table S7c in Additional data file 1), including those encoding proteins involved in proteolysis (ubiquitin-specific peptidase 46 and cathepsin Z), transforming growth factor-β signaling...
... containing μg DNA was used in each injection The rate of injection was μl/min and the needle was allowed to remain in situ for mins before being slowly retracted at the end of each injection The intrathecal ... original conformation (Ramachandra et al., 1998; Sauna and Ambudkar, 2000) It was demonstrated that PGP expression was highly expressed in most neuroblastomas and meningiomas (Spiegl-Kreinecker ... the cells 1.2.1.1 Naked DNA The simplest way for administration of DNA is direct injection of naked plasmid DNA into the tissue or vessel without any chemical carriers Naked DNA can give efficient...
... acid, capsaicin and resiniferatoxin, leading to burning pain or itch It is found that NGF and bradykinin can induce changes in TRPV1 by activating of cAMP-dependent (cyclic adenosine monophosphate-dependent) ... sphingomyelinase (ASMase), ASMase splice variant, Mg2+-independent neutral sphingomyelinase (NSMase), Mg2+-dependent NSMase and alkaline sphingomyelinase Among these, Mg2+-independent NSMase and ... been investigated For example, ceramide amplifies the action of TNF-α by stimulating acid and neutral sphingomyelinases and by inhibiting sphingomyelin synthase (Vivekananda et al 2001) In addition,...
... Tachykinin is the adopted generic name for the family of peptides to which substance P belongs There are three main mammalian tachykinin peptides: substance P itself, neurokinin A, and neurokinin ... trigeminal ganglion, like dorsal root ganglion, is likely to be glutamate (Wanaka et al., 1987) 15 (b) Trigeminal Sensory Nuclei The brainstem trigeminal sensory nuclei consist of the trigeminal ... sensory in function The motor trigeminal and intertrigeminal nuclei are associated with the motor functions of the jaw muscles Trigeminal Sensory Nuclear Complex The trigeminal nuclear complex is in...
... Brain andNervousSystem Histologic Type of Tumor Classification NOS, C716 - Cerebellum, NOS, C717 - Brain Stem, C718 - Overlapping lesion of brain and C719 - Brain, NOS; SPINE: C701 - Spinal ... III: CNS and Miscellaneous Intracranial and Intraspinal Neoplasms In: Ries LAG, Smith MA, Gurney JG, Linet M, Tamra T, Young JL, Bunin GR (eds) Cancer Incidence and Survival among Children and Adolescents: ... Melanomas National Cancer Institute 204 Exclude children (000-019) Exclude in situ cancers SEER Survival Monograph Chapter 25 Cancer of the Brain andNervousSystem For all analyses, brain cancer and...
... Yamada M, Nakagawa H, Fukushima M, Shimizu K, Hayakawa T, Ikenaka K: In vitro study on intrathecal use of 5-fluoro-2’deoxyuridine (FdUrd) for meningeal dissemination of malignant brain tumors ... Hashimoto K, Kodani M, Shigeoka Y, Nakanishi H, Touge H, Kurai J, Makino H, Takeda K, Yasuda K, Hitsuda Y, Shimizu E: Schedule-dependent synergism of vinorelbine and 5-fluorouracil/UFT against non-small ... degenerating axon (double arrows) and an axon with inter-laminar splitting (arrow) (f) A demyelinated axon with rarefaction of the axoplasm and possible axonal swelling (asterisk) and two neighboring...
... Iwase T, Ojika K, Mitake S, Katada E, Katano H, Mase M, Yoshida S, Ueda R: Involvement of CD45RO+ T lymphocyte infiltration in a patient with primary angiitis of the centralnervoussystem restricted ... cases and review of the literature Neurosurgery 1995, 36:173-179 11 Lee Y, Kim JH, Kim E, Park SH, Yim YJ, Sohn CH, Chang KH: Tumormimicking primary angiitis of the centralnervous system: initial ... M, Reganati P, Martinelli V, Terreni MR: Primary angiitis of the centralnervous system: serial MRI of brain and spinal cord Neuroradiology 2001, 43:599-607 14 Moore PM: Diagnosis and management...
... RE, Rivera B, Andratschke N, Ang KK: Effects of insulin-like growth factor-1 (IGF-1) and amifostine in spinal cord re-irradiation Strahlenther Onkol 2005, 181:691-695 Andratschke NH, Nieder C, ... 76:1045-1053 Pena LA, Fuks Z, Kolesnick RN: Radiation-induced apoptosis of endothelial cells in the murine centralnervous system: protection by fibroblast growth factor and sphingomyelinase deficiency ... Reiss K: Role of the insulin-like growth factor I/insulin receptor substrate axis in Rad51 trafficking and DNA repair by homologous recombination Mol Cell Biol 2003, 23:7510-7524 Nieder C, Andratschke...
... cytokines including interleukin-4 and -10 counteract the production of neopterin [21] The same is true for anti-inflammatory compounds including certain HMG-CoA reductase inhibitors (statins) and ... longitudinal subject examples before considering what these findings indicate and how neopterin might be used in the future While CSF neopterin has been known to be elevated in HIV infection and ... lineage Figure Induction of neopterin formation in brain cells Pro-inflammatory cytokines like interferon-γ (IFN-γ) induce expression of GTP-cyclohydrolase I in various brain cells As an intermediate...
... by freezing at -80°C Imaging and testing Four instruments were used to analyze the presence of nAuNPs in the cockroach’s brain and to study the interactions between nAuNPs and the brain tissue: ... decrease in activities after 23 days which can be attributed to changes in noise and vibration in the building Although proteins not break into ions, introducing charged particles into the nervoussystem ... eliminated by using only young males in this study The effects of temperature, humidity, and wind were diminished by maintaining them in a controlled environment However, the fluctuations in Rocha...