multidimensional nmr investigation of the neurotoxic peptide mastoparan in the absence and presence of calmodulin
Báo cáo khoa học: A single EF-hand isolated from STIM1 forms dimer in the absence and presence of Ca2+ ppt
... shown in Fig 1B, the distance between the two termini of the inserted Ca2+-binding sites in the model structure of the EF-hand of STIM1 is within ˚ 15 A Accordingly, a total of six glycine linkers ... Ca2+-coordinating loop positions and was introduced to perturb the Ca2+-binding ability of the grafted EF-hand of STIM1 (B) Modelled structure of the engineered protein with the grafted EF-hand Ca2+-binding ... it retains its native structure after the insertion of foreign sequences and in the presence and absence of Ca2+ ions, so that the in uence from the host protein to the inserted sites is minimized...
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Báo cáo khoa học: A steady-state competition model describes the modulating effects of thrombomodulin on thrombin inhibition by plasminogen activator inhibitor-1 in the absence and presence of vitronectin ppt
... PAI-1/VN complexes, suggests the involvement of the chondroitin sulphate of rl-TM in the binding of PAI-1/VN Indeed, both in the absence and presence of PAI-1, the interaction of rl-TM with immobilized ... binding of TM by thrombin Binding of the carboxy-terminal part of the reactive center loop of PAI-1 in the small cleft formed by the 60-loop and VR1 loop can be envisioned The kinetics of the interaction ... reduced The minor effect of TM on the rate of thrombin-VR1tPA inhibition by PAI-1 suggests that the binding between thrombin and TM, involving the VR1 loop of thrombin, is affected in the substitution...
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an investigation into the meaning and structure of a pictorial story - a systemic functional analysis = nghiên cứu cấu trúc và ngữ nghĩa của một truyện tranh phân tích theo quan điểm chức năng
... departure of the message” (Halliday 1994: 37), which in English coincides with the initial element(s) of the clause; and the Rheme is the remainder of the message The Theme may be a nominal group, ... checking the small monkey and the mother is waiting The seventh picture shows the doctor pointing at a picture of the small monkey with all parts of his body analyzed and the last image is of an injection ... four main subtypes: cognitive (thinking, knowing, realizing), perceptive (hearing, sensing, feeling), affective (loving, hating, adoring), and desiderative (wanting, desiring, wishing) In a mental...
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An investigation into the perceptions and actual behaviors of the teachers and the students at the faculty of Foreign Language of Ho Chi Minh City University of.PDF
... instructions and then putting the students into appropriate groups, telling them the aims of the activity or giving them some time to get ready for the task In the mean time, the students think that the ... common and recurrent themes in the data with the use of descriptive statistics - Interviewing the teachers and the students to get further information for the data in the questionnaires - Basing ... opportunities for the lazy students to another thing rather than getting involved into the discussion - The investigated teachers at the FFL – HUI think that putting students of the same proficiency,...
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An investigation into the perceptions and actual behaviors of the teachers and the students at the faculty of Foreign Language of Ho Chi Minh City University of20150227.PDF
... speaking so much and keeping interrupting and reminding students‟ errors during activity In short, the students and the teachers have quite similar ideas of what the instructors should during the ... actively in their lessons 4.3 For the administrations The administrations are responsible for controlling the students, the teachers, the learning schedules and the quality of teaching and learning In ... FFLHUI - Analyzing the questionnaires data by looking for and grouping the common and recurrent themes in the data with the use of descriptive statistics - Interviewing the teachers and the students...
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Investigation on the structure and magnetic properties of co2mnsi heusler alloy for spintronic application
... origin of the bandgap in Heusler alloys is caused by the d-d states hybridization of X and Y transition metals, as the DOS 14 in the vicinity of EF is dominated by the d-states The formation of ... attention in the field of spinelectronics due to its large band gap of 0.4eV in the minority spin band and high Curie temperature of 712°C According to Valet-Fert model, the use of highly spin-polarized ... allowed the spin-up electrons to propagate across the interface On the other hand, poor matching increased the scattering of spin-down electrons Seagate introduced an all-Heusler alloy CPP-GMR spin...
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An investigation into the structural and semantic features of sentence types in english and vietnamese detergent product advertisements discourse
... powerful influence over people and their behavior This is especially true in the fields of marketing and advertising The choice of language to convey specific messages with the intention of influencing ... remains some other aspects awaiting investigation We strongly suggest further studies on the following areas: An investigation into structures and pragmatics of English and VDPAs discourse An investigation ... types in advertisement discourse in the two languages in terms of structures and semantics - Synthesizing and draw conclusion - Giving some implications in teaching and learning English and some...
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báo cáo hóa học:" Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs" pot
... responses within individual patients, rather than patient groups Maintaining the levels of TAAg-specific CD8+ T cells in the circulation is the summation of the capacity to generate them and their possible ... diftitox inducing disease regression (partial and complete in 20–30% of patients) This is due to inhibition of protein synthesis in cells expressing high and intermediate affinity IL-2 receptors, thereby, ... drafting and reviewing the manuscript, including statistical analysis MMA, AJM, JME, ST: recruitment of patients into the study and reviewing the manuscript All authors read and approved the final...
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An investigation into the syntactic and semantic features idioms containing words denoting kitchen utensils in english and vietnamese
... terms of their structures and classify them in the accordance with their semantic features - Finding out the similarities and the differences in the syntactic and semantic features of EIKUs and ... quoted in this study are completely the same as the original materials with the clear - Presenting the limitations of the study information of authors, the name of publishers, the time, and place of ... by looking at the meaning of the component words In other words it can be said that the meaning of an idiom is the meaning of one word Chapter METHODS AND PROCEDURES 3.1 RESEARCH DESIGN In order...
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Tài liệu Báo cáo khoa học: Tachykinin-related peptide precursors in two cockroach species Molecular cloning and peptide expression in brain neurons and intestine docx
... TKRPs in the brain and intestine, respectively This could result in the gut-specific accumulation of such peptides, whereas in the brain cleavage products of these TKRPs are abundant Apart from these, ... demonstrated the occurrence of the different TKRPs in glomeruli of the tritocerebrum and in cells of the optical lobe Results Cloning of cockroach preprotachykinin cDNAs Using degenerated PCRs and RACE, ... americana midgut in this investigation and both peptides were chemically isolated from the brain and intestine of L maderae [14,15] The other N-ter3370 minally extended peptides LemTKRP-3 and PeaTKRP-3...
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IMPAIRED CARDIOVASCULAR RESPONSES TO GLUCAGON-LIKE PEPTIDE 1 IN METABOLIC SYNDROME AND TYPE 2 DIABETES MELLITUS
... determine the role of GLP-1R in mediating the left ventricular performance enhancing effects of exendin-4, GLP-1 (7-36), and GLP-1 (9-36) The results of these investigations are inconsistent, and ... through a catheter introduced into the thoracic aorta through the left femoral artery Another catheter, inserted into the right femoral vein was used to maintain anesthesia, and administer sodium ... to the route of administration and/ or species differences Furthermore, the effects of GLP-1 on coronary blood flow and vascular tone are unknown in humans and in the settings of MetS/T2DM Further...
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Báo cáo khoa học: High-resolution NMR studies of the zinc-binding site of the Alzheimer’s amyloid b-peptide pdf
... zinc addition, indicating that the aromatic ring of Tyr10 is not involved in binding of the metal Instead, the e and d resonances of the histidines show significant intensity losses, of > 80% The ... prominent close to the binding site We conclude that zinc binding induces increased order in the N-terminus of the peptide This is reflected by the increased R2 in this region, and also by the increased ... rise to a model of the induced structure of the peptide when bound to zinc (Fig 6) The binding involves the histidines and the N-terminus There is a turn at Glu3, bending the N-terminus towards...
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Báo cáo khoa học: Quenched hydrogen ⁄deuterium exchange NMR characterization of amyloid-b peptide aggregates formed in the presence of Cu2+ or Zn2+ ppt
... assembly and pinpointing the mechanism by which metals guide the path of aggregation away from the fibrillar trail The present investigation assessed how the growth and architecture of Ab(1–40) and ... morphologically distinguish aggregates formed in the presence of Cu2+ from those formed in the presence of Zn2+ Taken together, these results suggest that Ab aggregates formed in the presence of Cu2+ or ... assembled, the N-terminal metalbinding region of the peptide will be in close proximity to both the C-terminal and turn residues, possibly interfering with these regions This explains how an...
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Báo cáo Y học: Conformational analysis by CD and NMR spectroscopy of a peptide encompassing the amphipathic domain of YopD from Yersinia potx
... 6.3 (A) In the absence of purified LcrH, and (B) In the presence of purified LcrH to give a peptide/ protein molar ratio of : The peptide residues Tyr291 and Val292 identified to bind LcrH are indicated ... mimics the interaction between the peptide and LcrH Therefore, analysis of LcrH binding on the dynamics of peptide aggregation warrants further investigation CONCLUSIONS In this study, we have initialized ... YopD278)300 and LcrH was observed from line-broadening and chemical shift differences within the amide region from a 1D NMR spectrum of the free peptide and the peptide- protein solution (Fig 10) The...
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nmr methods for the investigation of structure and transport
... organized the continuation of the research unit after the DFG funding as well as Prof Kasper, Prof Kind, Prof Nirschl, and Prof Elsner Prof Nirschl, Prof Kind, Prof Wilhelm, and Prof Elsner contributed ... t D and hence the number of spins By linearity of the Fourier transform the direct relation between the peak integral and the number of spins of the corresponding chemical group holds for the ... real, the oscillating imaginary part of the sum in general leads to a small imaginary part of Qn The maximum of the real part of the sum is N times higher than the amplitude of the oscillating...
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An investigation into the reality of teaching and learning speaking skills to the 2nd year non-major english students at pre-intermediate level of proficiency at hanoi university of industry
... improve the situation of teaching and learning speaking English to the year non-major English students would be made The thesis consists of three main parts: the introduction, the development, and the ... DEPARTMENT OF POST GRADUATE STUDIES CANDIDATE’S STATEMENT I certify that the minor thesis entitled: “An investigation into the Reality of Teaching and Learning Speaking Skills to the 2nd year ... conclusion The introduction - gives rationale for the study and sets up the aims, scopes and methods of the study The develoment - which is considered as the main part of the study, includes three...
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An investigation into the style of the english language used in advertising slogans issued by some world - famous airlines
... limit of the range of possible interpretations, and on the other hand, a supporter of the intended interpretation He states as follows: The use of linguistic form identifies a range of meanings ... denoting the action of flying such as “sky”, “wings”, the air”, “up” and so on Alitalia The wings of Italy -AlitaliaYour Island in the Sky -Air PacificSomething special in the air -American Airlines- ... France One of the best places on earth AIR INDIA India New Zealand your place in the sky Being there is everything Air New Zealand Air Pacific Your Island in the Sky Air Tanzania The wings of Kilimanjaro...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25