... Fig Molecular modeling of the dimeric structureof LPL Two dimeric model structures of LPL were constructed using INSIGHT II version 2000 on a Silicon Graphics workstation The model structureof ... steps of 1.0 fs time-step RESULTS Model structureof human LPL All model structures of dimeric human LPL were constructed using the INSIGHT II program and were based on the crystal structures of ... dimeric form of LPL, the model structureof monomeric LPL was duplicated and superimposed on the crystal structureof the horse PL dimer After the energy minimization by setting at iteration of 300...
... [14] gave a molecular mass of 505 ± 35 kDa in a first experiment and one of 483 ± 27 kDa in a second experiment, resulting in an overall molecular mass of 494 ± 33 kDa For the subunits of D magna ... could not be identified Molecular mass of Hb subunits The reported molecular mass of Daphnia Hb didomain subunits varies between 31 and 40 kDa [14,24] Hb proteins of twice this molecular mass have ... quaternary structure After purification of red D magna hemolymph by chromatofocusing [removal of ring-like molecules (‘ferritin’), but retention of high Hb quantities], numerous different views of the...
... properties to Program Offices (e.g., Office of Water, Office of Solid Waste and Emergency Response, Office of Prevention, Pesticides and Toxic Substances) and Regional Offices Also, SPARC has been used ... number ofmolecular structures The values of these latter parameters, in most instances, must be derived from measurements or from the expert judgment of specialists in that particular area of chemistry ... potential of a particular S to "exert" a given effect (Independent of the property, C and R), molecular network conduction, which describes the "conduction" properties of the molecular structure...
... present the 3D structureof the native CBH IB from T emersonii, the first structureof any protein from this source and the first structureof a native fungal CBH core (glycoprotein) Molecular cloning, ... during the structure solution of the native enzyme Family contains both CBHs and endoglucanases The structureof CBHs is distinguished from that of endoglucanases by the presence of loops of polypeptide ... 1.25 U of Pfu DNA polymerase, · Pfu reaction buffer, 200 lM of each Ó FEBS 2004 Structure and analysis of T emersonii CBH IB (Eur J Biochem 271) 4497 deoxynucleotide triphosphate and lM of the...
... relax of beta barrel structureof Pla and the progressive approximation and stabilization between the cleavage site of Plg into the extracellular loops of Pla, followed of the increase of hydrogen ... of Biochemistry, Science Institute, University of Iceland, Reykjavik, Iceland, 2Laboratory ofMolecular Genetics, Institute of Biology, University of Iceland, Reykjavik, Iceland, Department of ... sites of 20S complexes We performed exible docking studies of analogues of a natural product TMC-95A using 1JD2 crystal structure to describe the active site of protein and the position of the...
... two X-ray structures, one of WT and the other of rWT metHb, exhibit differences that include important portions of the protein that we have characterized above Thus parts of the FG corner move ... secondary Fig Schematic representation of the heme pocket of Pe Hb as found in the crystal structureof Pe metHbH2O [16] and as conrmed herein by solution 1H NMR of Pe metMbCN Proximal and distal ... the tilt of the major magnetic axis, z, away from the heme normal (z axis), a is the angle between the projection of the tilt of the z axis on the xÂ, y plane (dened direction of tilt of z and...
... the utility of this approach in estimating the strength of ordered polymers The effects ofmolecular weight on the strength of glassy polymers is to increase from near zero at very low molecular ... discussion of these phenomena The molecular weight dependence of a polymer is strongly related to the entanglement molecular weight Above 2Me, the viscosity of the melt increases as the 3.4 power of ... polystyrene as a function of temperature Shear Yielding There have been many attempts to describe the yield strength from the molecular point of None of these relates well to basic molecular parameters...
... necessity for confining ourselves to the use of hexagons If, for example, v/e foim the surface structureof pentagons instead of hexagons, the number of exposed corners on each compartment would be reduced ... characteristics of these two structurss can, howev3r, be combined i? If we assume that the valencies of the carbon atom are arranged like the corners of a regular tetrahedron, and that the three valencies of ... vulnerable Regardless of how ;' -many additional hexagonal compartments we add to this structure, the maximum number of exposed corners can never be less than two But at the surface of the organism...
... organization of a system, can be and of time function of redundancy (see Annex) Evolution of the organization as a expressed as a be calculated function of time can thus different types of showing ... 1976), as in the case of secondary metabolism (Terashima and Fukushima, 1988) these authors: in Fagus, the lignin moiety of LCC would consist of a small number of extremely large molecular fractions, ... Cy-hydroxyls of a monomeric propane chains (Fig 1C5to Molecular associations and cell wall lignification Formation ofmolecular associations with other cell wall components is the third main feature of...
... curves of FRα double mutants .75 Figure 29 Comparison of FRα and chicken riboflavin binding protein 79 Figure 30 Structure alignment of human FRα and FRβ 81 Figure 31 Structureof FRα in ... X-ray crystal structureof human TS in complex with dUMP and raltitrexed .98 Figure 38 Chemical structures of raltitrexed and BGC945 103 Figure 39 Chemical structures of pemetrexed ... form of folate in circulation is 5-methyl tetrahydrofolate (5-methyl THF) [7] a) b) Figure Chemical structureof folic acid and folate derivatives a) Constitution of folic acid b) Tetrahydrofolate...
... MOLECULAR TRANSPORT AND STRUCTUREOF DNA IN A CONGESTED STATE ZHU XIAOYING (Ph.D.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTER OF PHILOSOPHY DEPARTMENT OF PHYSICS NATIONAL UNIVERSITY OF SINGAPORE ... the method of multiple-particle tracking to measure the microviscosity and degree of heterogeneity of solutions of DNA over a wide range of concentration and lengths to identify some of the topological ... Summary In this thesis, the molecular transportation properties and the structureof supercoiled DNA is investigated To study dynamic properties of DNA, the viscoelastic moduli of lambda phage DNA through...
... capacity at constant volume of crystals with hcp structure by SCFM Using SCFM, only taking account ofmolecular rotation, the rotational free energy of crystals√with fcc and hcp structures in pseudo-harmonic ... m is the mass of particle at lattice node, ωx is the frequency of lattice vibration on direction x (or y), kx , kxy and γ are the parameters of crystal depending on the structureof crystal lattice ... the lattice vibration and the molecular rotation have important contributions to thermodynamic properties ofmolecular cryocrystals of nitrogen type Table Values of B and U0 for β−N2 and β−CO...
... rotational free energy of the system of non-interaction rotators and is one of angles determining the position of symmetric axe ofmolecular field for the coordinate system of crystal In self-consistent ... constant volume of the molecular crystals of type N2 is studied by combining the SMM and the SCFM This paper represents further investigations of anharmonic effects of lattice vibrations and molecular ... at constant pressure, etc) of the crystals of type N2 II THEORY Using SMM, only taking account of lattice vibration, the vibrational free energy of crystals with fcc structure is approximately...
... fact was one of the happy consequences of the hierarchical structure Testing level (the real-time clock and processor allocation) implied a number of testing sequential processes on top of it, inspecting ... process blocked in the course of task execution relies on the other processes for removal of the barrier Essentially, the proof in question is a demonstration of the absence of "circular waits": process ... cooperation of a set of such sequential processes can be established by discrete reasoning; as a further consequence the whole harmonious society of cooperating sequential processes is independent of...
... independently of the pre-initiation factors necessary for cap-dependent translation The three-dimensional structureof the HCV IRES bound to the 40S ribosomal subunit illustrates the molecular basis of ... Assistant Professor of Medicine and Staff Physician at the Department of Gastroenterology and Hepatology, University Hospital Freiburg, Germany Since 2004 he is the head of the Division of Gastroenterology ... intracellular membranes and is required as a cofactor for the NS3 serine protease The crystal structureof the NS3-4A complex revealed that NS4A is an integral component of the enzyme core [41] Surprisingly,...
... is the appearance of serum markers of HBV infection that establishes the diagnosis of the disease Of these, HBsAg is considered to be the sentinel marker for the confirmation of acute infection ... necessary should the rate of emergence of resistance and the impact of such mutations turn out to be clinically relevant for therapy management Molecular Mechanisms of Drug Resistance HBV is ... technology, molecular beacons) that decrease the number of handling steps, reduce contamination, and increase throughput and the accuracy of quantification will further enhance the utility of these...
... characteristics of carbon stable isotope and fatty acid structureof Z japonica Furthermore, we compared the characteristics of carbon stable isotope and fatty acid structureof Z japonica with those of the ... from that of the roots and rhizomes For example, the δ13C of HCO3- is higher than δ13C of CO2 in sea water Characteristics of fatty acid structure in Z japonica We found about 30 kinds of fatty ... characteristics of the fatty acid structure in the leaves and stems differ from those of the roots and rhizomes because the content of the fatty acid 18:3n3 in the leaves and stems differ from that of the...
... Table of contents Acknowledgement Table of contents Chapter one: Introduction 1.1 Rational of the study 1.2 Aims of the study 1.3 Scope of the study 1.4 Methods of ... 1.6 Design of the Study The paper is designed in four chapters Chapter one: The introduction presents the rationale of the study, the aims of the study, scope of the study, methods of the study, ... for many areas of English grammar It is called functional because of his development of the theory of the ideational, interpersonal, and textual metafunctions functional components of meaning in...
... shows the contribution of this strategy to the development of plants with biofarming potential in the frame of a high demand of natural and ecologically accepted sources of renewable compounds ... the evolution of vascular plants The case of Fld and Cyt c6 shows that reintroduction of these genes in the proper subcellular compartment of model and crop plants restored some of the selective ... export of the excess of reducing power via the malate valve, and productive consumption of the surplus of NADPH by the Calvin cycle Finally, as is the case with iron deficiency, the extent of protection...
... bars Molecular Farming of Antibodies in Plants 37 rearrangements of the germ-line immunoglobulin genes This part of the molecule is responsible for antigen recognition and binding The remainder of ... 3 Molecular Farming of Antibodies in Plants 53 After promoter choice, the next most important aspect of construct design is the inclusion of sequences that control subcellular targeting of the ... distinct glycan structures (Ikonomou et al., 2003) A more recent development is the production of antibodies in the milk of transgenic animals (Dyck et al., 2003) A disadvantage of animals, in...