molecular and cellular aspects in cardiovascular research
Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: regulation, molecular and cellular communication at the neurovascular interface pdf
... possible, in which pericytes induce and guide vessel sprouting In the developing human brain, migrating pericytes are found in front of growing vessels and pericyte-driven angiogenesis participates in ... transporter system used by proteins, such as insulin, transferrin and leptin, to cross the BBB [13] Molecular basis of brain angiogenesis and barriergenesis Hypoxia and the hypoxia-inducible factor system ... origin [78] According to the monocyte hypothesis, during embryogenesis, and even in adults, migrating monocytes enter the brain via blood vessels and then differentiate into certain types of brain...
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Tài liệu Báo cáo khoa học: Molecular and cellular specificity of post-translational aminoacyl isomerization in the crustacean hyperglycaemic hormone family docx
... (made in rat) and gp-anti-dW4 (produced in guinea pig), two antisera discriminating CHH isomers (gp-anti-pQl made in guinea pig and rb-anti- pQd in rabbit) [38] and an antiserum raised against ... lobster, VIH and CHH are synthesized and released by different cellular types in woodlouse [46] and in Norway lobster [47] Similarly, moultinhibiting hormone and CHH are localized in distinct neurosecretory ... Axon terminal containing D-Trp4 VIH (G) Two neighbouring axon terminals, one containing D-Trp4 VIH and the other D-Phe3 CHH (H, I) Higher magnifications of D-Trp4 VIH and D-Phe3 CHH containing granules,...
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molecular and cellular biology of neuroprotection in the cns - christian alzheimer
... potentially increasing excitotoxic damage Calcineurin has been convincingly demonstrated to be involved in neuronal cell death since pharmacological experiments using the calcineurin inhibitors ... converts L-arginine into NO and citrulline: (1) neuronal NOS (nNOS), (2) inducible or immunologic NOS (iNOS) in microglia and astrocytes and (3) endothelial NOS (eNOS) predominantly in endothelial ... MAP kinase and c-jun N-terminal kinase or stress-activated kinase (JNK/SAPK) which promote cell death.322 SAPK/JNK is activated by tyrosine kinase and elevated intracellular calcium, and in primary...
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Báo cáo sinh học: "Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication" pot
... strong binding in vivo between Tax-2 and NF-YB In fact, and again for the first time, we demonstrated in this investigation that both transfected, thus overexpressed, and endogenous NF-YB could interact ... and Western blotting Human embryo-derived kidney cell line 293T was maintained in DMEM supplemented with 10% FCS and mM glutamine at 37°C and 5% CO2) 293T cells were transfected with expressing ... proteins in whole cell extracts was also examined by WB (input) with antibodies directed against NFYB, Flag and V5 In the presence of CIITA, Tax-2 is predominantly accumulated in the cytoplasm and...
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o cáo hóa học:" Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication" potx
... strong binding in vivo between Tax-2 and NF-YB In fact, and again for the first time, we demonstrated in this investigation that both transfected, thus overexpressed, and endogenous NF-YB could interact ... and Western blotting Human embryo-derived kidney cell line 293T was maintained in DMEM supplemented with 10% FCS and mM glutamine at 37°C and 5% CO2) 293T cells were transfected with expressing ... proteins in whole cell extracts was also examined by WB (input) with antibodies directed against NFYB, Flag and V5 In the presence of CIITA, Tax-2 is predominantly accumulated in the cytoplasm and...
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Báo cáo y học: "4th meeting of the EU research network EUROME: From the identification of genes and cellular networks in murine models of arthritis to novel therapeutic intervention strategies in rheumatoid arthritis, London, UK, 9 March 2004" pot
... substratum (extracellular matrix) More importantly, knocking out the expression of gelsolin, an actin-binding protein with filament-severing properties found downregulated in RA, resulted in mild exacerbation ... expression of antiapoptotic proteins Bcl-2 and members of the inhibitor of apoptosis family (cIAP-1, XIAP and survivin, which directly bind to and inhibit caspases), was strikingly reduced Dr Brigitte ... cytosis by binding the complement inhibitor factor H (and in some cases, also the factor H-like protein 1) to its surface Binding is mediated by two types of plasmidencoded protein, class I (20...
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MOLECULAR AND CELLULAR MECHANISMS LEADING TO SIMILAR PHENOTYPES IN DOWN AND FETAL ALCOHOL SYNDROMES
... Activated Akt in DS and FAS Understanding the mechanisms behind the craniofacial and neurological deficits of DS remains integral in current research While Dyrk1a and Rcan1 have been implicated in both ... place on anethesized mice and was initiated in an induction chamber with 22 isoflurane levels at 1.5% and 0.8-1.2 liter/min, and maintained at 0.5 liter/min during the 45 minutes scans Both model ... essential in specific tissues of the developing mouse including the brain (SASAKI et al 2010) Proteasomes are an integral part in sustaining the immune system They play an important role of removing invading...
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Molecular and cellular functions of the alternatively spliced isoforms of GDNF receptor complex in neuronal differentiation
... cysteine-rich domains with various lengths of C-terminal extensions (2, 61) Domain (D2) is involved in the binding of GFLs (50, 62-64) while Domain (D3) provides a stabilizing effect The Nterminal ... identical extracellular GFL and GFRα binding domains, RET9 and - 29 - RET51 seem to function as independent signaling complex in cultured sympathetic neurons and neuronal cell lines (117, 118) ... With an increasing number of RET binding partners, it is now believed that each phosphotyrosine residue may serve as a competitive binding site, resulting in divergent signaling outcomes, in a cell...
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IMAGING AND RADIOANALYTICAL TECHNIQUES IN INTERDISCIPLINARY RESEARCH -FUNDAMENTALS AND CUTTING EDGE APPLICATIONS potx
... IMAGING AND RADIOANALYTICAL TECHNIQUES IN INTERDISCIPLINARY RESEARCH FUNDAMENTALS AND CUTTING EDGE APPLICATIONS Edited by Faycal Kharfi Imaging and Radioanalytical Techniques in Interdisciplinary ... Techniques in Interdisciplinary Research - Fundamentals and Cutting Edge Applications Coùncidence lines Detectors corona Coùncidence lines Detectors (a) (b) (c) Figure Principle of PET imaging and 2D and ... nuclear medicine and has particular value in the cardiology cycle of care This hybrid machine allows table to remain stationary in many cases, eliminating complexities inherent in table indexing, acquires...
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Common format and punctuation errors in English research writing potx
... expand in Asia, and increase its mobile product line → The company will expand in Asia and increase its mobile product line The word “company” is the subject of both verbs No comma before and ... abbreviations in subheadings Incorrect: 3.6 Water solubility index (WSI) The water solubility index (WSI) increased when both temperature and chlorine concentration increased Abbreviations in body ... words “So,” and “but,” should not be used in academic writing at the beginning of a sentence (unless it is quoted speech in qualitative research) Their job is to combine two main clauses in a compound...
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image analysis, sediments and paleoenvironments developments in paleoenvironmental research
... ruler and color/gray charts should be acquired at the beginning and the end of each working session, keeping in mind the need to maintain the image acquisition conditions strictly constant during ... They include among other things, the characteristics and settings of the acquisition device (e.g., depth of field, current intensity in a SEM filament) and any event occurring during the working ... care is taken to maintain identical settings and lighting during a session In particular, automatic camera settings that vary exposure and aperture should be avoided A final point to consider is...
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Molecular and Cellular Signaling docx
... complex prolactin-inhibiting hormone phosphoinositide 3-kinase related kinase phosphatidylinositol phosphatase protein kinase A protein kinase B protein kinase C protein kinase G protein kinase R phospholipase ... Congress Cataloging -in- Publication Data Beckerman, Martin Molecular and cellular signaling/Martin Beckerman p cm.—(Biological and medical physics, biomedical engineering, ISSN 1618-7210) Includes bibliographical ... proteins involved in cell-to-cell communication are organized into signaling pathways In a signaling pathway, there is a starting point, usually a receptor at the plasma membrane, and an endpoint...
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Báo cáo y học: "Cartilage-specific autoimmunity in animal models and clinical aspects in patients – focus on relapsing polychondritis" ppsx
... production in RP patients [15,16] Surprisingly, a more prominent response was seen for CIX and CXI in a patient presenting a fatal tracheomalacia, indicating CIX and CXI rather than CII as being involved ... dominating symptom is inflammation in the peripheral joints characterized by redness, swelling and pain, which mimic the symptoms of arthritis in RP patients In the majority of the rodent strains, ... have not yet been investigated in RP patients Adjuvants and oils can induce arthritis in many rat strains [33–36] and auricular chondritis in Wistar rats [21] Finally, in FH and Wistar rats, chondritis...
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Báo cáo khoa học: " Conserved peptides within the E2 region of Hepatitis C virus induce humoral and cellular responses in goats" pptx
... IgG Following a washing step, using 0.05% (v/v) PBS-T20 (pH 7.2), and non specific binding sites was blocked by incubation with 0.2% Bovine serum albumin in PBS at 37°C for hours Washing by PBS-T20 ... C-terminal to HVR-1 of the E2 protein were designed and synthesized This was done commercially by ANASPEC, Inc, (San Jose CA, USA), in the amide form, using standard solid phase synthesis involving ... interactions and the presence of immune-dominant variable elements Therefore, several investigators have focused on E2 glycoproteins (gps) for developing HCV vaccines including purified recombinant...
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Studies on the molecular and cellular mechanisms underlying the process of learning and memory formation body
... Timm’s staining and immunohistochemistic staining are the main methods used for detecting sprouting of the MFs terminals in brain sections As described above in 1.3, sprouting of the MFs in CA3 ... sprouting into SO in CA3 after water maze training (Rekart et al., 2007a) What is more, even no kainate induced MFs sprouting and no induction of GAP-43 mRNA in granule cells after these kainate-induced ... MFs terminal fields, days after the last day of training, from the SL of CA3 into the SO and SP using Timm’s staining In contrast, no changes in the area of the MFs terminals were observed in animals...
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Studies on the molecular and cellular mechanisms underlying the process of learning and memory formation
... Timm’s staining 87 4.2.2.2 Nissl staining 88 4.2.3 Mapping and quantifying Zn: Nuclear microscopy 88 4.2.3.1 Introduction of nuclear microscopy .88 4.2.3.2 Mapping and quantifying ... 3.3.3 Overtraining-induced expansion of mossy fiber terminal fields was observed in Wistar rats not in Lister-Hooded rats .61 v 3.3.4 MEMRI analysis of learning-induced remodeling of the ... 18 1.3 Mossy fibers in learning and memory……………………………………… 19 1.3.1 Role of mossy fibers plasticity in learning and memory 19 1.3.2 Species and strains difference in mossy fibers…… 21...
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Co operation between humoral and cellular immunity in pulmonary lung inflammation
... placing it in a chamber into which oxygen and isoflourane were introduced It was manually restrained by gripping the skin over the back of the neck and holding it in a vertical position Using ... remodelling and eosinophils Eosinophils were genetically ablated in mice by the deletion in the high affinity GATA-binding site in the GATA-1 promoter After a prolonged allergen challenge using a ... cell numbers in the airways and have detected histamine, Prostaglandin D2 (PGD2), and tryptase in BAL fluid both in symptomatic asthma and after allergen inhalation challenge, suggesting mast cell...
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Proteolytic and cellular mechanisms in prohormone and proprotein processing 1570595534
... studies indicate that proinsulin and VSV G protein are segregated into distinct vesicles from those containing the ER retrieval KDEL receptor.46 Interestingly, the proinsulin-containing vesicles ... Hormones in the Secretory Pathway Proteolytic and Cellular Mechanisms in Prohormone and Proprotein Processing Prohormone cleavage and activation continues in the ISG, the vesicular intermediate linking ... Proteolytic and Cellular Mechanisms in Prohormone and Proprotein Processing Targeting and Activation of Peptide Hormones in the Secretory Pathway identified, trafficking of these proteins may also involve...
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Báo cáo hóa học: " Research Article Class-Based Fair Code Allocation with Delay Guarantees for OVSF-CDMA and VSF-OFCDM in Next-Generation Cellular Networks" ppt
... multicode interference, whereas increasing frequency domain spreading increases frequency diversity Thus a trade-off between reduction of multicode interference and increased frequency domain spreading ... triangle in the figure In Figure 5(b), calls A and B use codes C(2, 0) and C(2, 1) as the time domain codes, respectively This increases time domain spreading and also reduces intrauser multicode interference ... algorithm, determines the time domain and frequency domain spreading factors so that the frequency domain spreading is maximized while keeping the intrauser multicode interference on time domain codes...
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Báo cáo hóa học: "Research Article Dynamic Resource Assignment and Cooperative Relaying in Cellular Networks: Concept and Performance Assessment" pot
... Scenario A LOS link is assumed for nodes in the same street and a NLOS link for nodes in different streets and MSs are located inside of a building or in a street The corresponding channel and path-loss ... performance of a multicell WINNER network in a wide area scenario has also been studied in [6] Under the assumption of an LOS BS-RS and RS-MS link and NLOS BS-MS and interfering links the saturated throughput ... A LOS link is assumed for nodes in the same street and a NLOS link for nodes in different streets and MSs are located inside a building or in a street Details of the propagation model and additional...
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