... levels of Lac and mI in the hippocampus of the aged rats These findings are consistent with the data reported in other ex vivostudies [12,13] Nevertheless, the increase in Lac is an interesting finding ... changes ofbrain tissue to a minimum, to avoid increases in tissue lactate and GABA levels [14] Data processing Proton assignments were made by comparing resonances of individual D2O solutions of ... is an interesting finding in that the Lac level in the hippocampus might be considered a useful marker of aging Indeed, increased Lac levels have been found in the brains of healthy elderly people,...
... place in the kidney and liver It is reduced in the brainof patients with brain tumor or infectious brain masses (Wang, 1998) Invivo NMR measurements inbrain observe the total of both creatine ... a possible artifact of the sample preparation Acetate concentrations in human brain were observed to increase inbrain tumors, ischemia, and invivoinbrain abscesses (Martin, 1994) Acetate is ... metabolites of different types ofbrain tumors b) Quantitative studiesof major brain metabolites of both human and mouse c) Make it possible to clinical diagnosis ofbrain tumors by NMR spectra of metabolites...
... attractive Proton NMR spectroscopy, which in principle enables detection of all hydrogen-containing molecules, has turned into a commonly applied technique for metabolic profiling of biofluids, among ... with animals and care of experimental animals Experimental samplings Each cow was sampled for one day after being fed the experimental diet for 14 d On sampling days, continuous infusion of p-aminohippuric ... concentrate containing profollowing intake and andof arterial blood developed dyspnea pylene glycol clinical force feeding with concentrate containdid propylene(circle) (triangles)tocow that in two cows...
... object contours can be delineated through finding out the minimal paths instead of minimizing the energy E directly It can be shown that in order to minimize Equation 2.15, the initial curve should ... consuming In addition, the manually obtained results are not reproducible With the fast increasing size and number of medical images, the use of computers in facilitating their processing and ... BRAIN VASCULATURE SEGMENTATION FROM MAGNETICRESONANCE ANGIOGRAPHIC IMAGE DORNOOSH ZONOOBI (B.Eng (COMPUTER Engineering)) A THESIS SUBMITTED FOR THE DEGREE OF MASTER’S OF ENGINEERING DEPARTMENT...
... removal ofinvivo H MRS signals of 10 MagneticResonanceSpectroscopyMagneticResonanceSpectroscopy human brain using HLSVD with a model order of 25 (K = 25) Nevertheless, suppression of unwanted ... Formation of a priori information by spectral simulation, MagneticResonancein Medicine 40(6): 812815 2 13 C MagneticResonanceSpectroscopyin Neurobiology - Its Use in Monitoring Brain Energy Metabolism ... Characterization of macromolecule resonances in the H NMR spectrum of rat brain, MagneticResonancein Medicine 30(1): 3844 Belki , D & Belki , K (2006) InvivoMagneticResonanceSpectroscopy by the fast...
... INADEQUAT Phổ cho thấy mối tương quan ngang qua nối nhờ phổ cho biết phân tử cacbon kề bên cacbon Phổ 1D 13C INADEQUAT thường sử dụng khó xác định mối lien hệ 13C, 13 C Ngược lại phổ 2D 13C INAQUAT ... (δ6-δ7) x 500 = (δ7-δ8) x 500 = 7.15 làm tròn với số lẻ J = 7.1 Hz cường độ peak nhóm theo %Int = 1:2:1 + Tại singlet peak chọ làm tín hiệu với δ = 1.9907 làm tròn với hai số lẻ δ = 1.99 ppm + Tại ... loại phổ cho biết mối tương quan proton-proton với nhau: proton gem (germinal, hai proton gắn cacbon); proton vic (vicinal, hai proton gắn hai cacbon kề nhau) 2.2 Phổ 1H-13C HETCOR Phổ COSY dị...
... medium containing creatine, both cell types accumulated significant amounts ofcreatine On the other hand, when these creatine- loaded cells were placed in creatine- free medium, their creatine contents ... actual creatine transport The enzymes intimately linked with creatine biosynthesis were also studied We conducted our studiesin the solid sarcoma tissue of mice (induced with carcinogen in hind ... for creatine biosynthesis, AGAT and GAMT, in all three types of malignant cell lines suggests the possible presence ofcreatinein these cells However, as noted above, the intrinsic level of creatine...
... technique that includes cartilage in the estimation of joint contact patterns In summary, we have developed a technique for characterizing invivo glenohumeral joint contact patterns during dynamic ... repair: re-establishing the footprint of the rotator cuff,” Arthroscopy, vol 19, no 9, pp 1035–1042, 2003 [15] S Tashman and W Anderst, In- vivomeasurementof dynamic joint motion using high speed ... recommendation on definitions of joint coordinate systems of various joints for the reporting of human joint motion—part II: shoulder, elbow, wrist and hand,” Journal of Biomechanics, vol 38, no...
... Zwicker et al.: Biological in- vivomeasurementof dose distribution in patients’ lymphocytes by gamma-H2AX immunofluorescence staining: 3D conformal- vs step-and-shoot IMRT of the prostate gland Radiation ... be taken into consideration, e g circulation of the lymphocytes in the body during irradiation [4] The purpose of this study is to visualize the cellular effect of ionizing radiation during prostate ... was irradiated in- vitro for independent measurements on different days Utilization of volunteers was necessary because of intended test repetition, not suitable for patients Interindividual differences...
... PiT1-binding immunoadhesin generated by fusing the aminoterminal residues of the GALV (SEATO strain) Env, comprising the signal peptide, the RBD and the proline-rich region, to the rFc tag, herein, ... significant differences in body weight between normal and intoxicated animals Regional GLUT1, PiT1 and PiT2 distribution in the brainof normal mice Cortex staining: GLUT1 staining was heterogeneous ... detection of GLUT1 by immunoblotting performed in rats has previously shown that GLUT1 is expressed in all brain regions but in less abundance in the striatum, the thalamus and the brainstem [24] In...
... Fleischmann BK, et al: Monitoring of implanted stem cell migration in vivo: a highly resolved invivomagneticresonance imaging investigation of experimental stroke in rat Proc Natl Acad Sci USA ... and injected in right or left leg muscles, respectively, were detected by invivo MRI and by dextran immunofluorescence (A) Representative image ofinvivo MRI (transverse plane) showing hypointense ... Alizarin Red staining for 30 minutes in water All reagents used in this experiment were from Sigma-Aldrich Co Page of 13 micromass cultures, the cells were seeded in μl droplets in the center of...
... cancer of mm in diameter and IVIS imaging system and MagneticResonance Imaging, investigated the feasibility of as-prepared nanoprobes for non-invasive invivo targeted dual modal imaging of gastric ... left-shift of 40 nm, which was due to decrease of the polarization rate of the surrounding molecules, and resulting in the decrease of stokes displacement, finally resulting in a blue shift in the ... Department of Bio-nano Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of...
... performed in these studies at a distance from the injury Magneticresonance imaging findings in specific critical neurological conditions Traumatic brain injury Conventional magneticresonance imaging ... days) Characteristics Brain swelling Brain swelling Absence ofbrain swelling Diffuse atrophy and dilatation of the ventricles DWI Hypersignals in the cortex, in the thalamus and in the basal ganglia ... Magneticresonancespectroscopy profile of the pons after traumatic brain injury (a) Normal profile The peak of N-acetyl-aspartate (NAA) is higher than the peaks of choline (Cho) and creatine (Cr)...
... producing images of the brain, due to the ability of MRI to record signals that can distinguish between different soft tissues such as gray matter and white matter [3] In imaging the brain, two of ... registered brain atlas as a model for healthy brains Then, they make use of the robust estimates of the location and dispersion of the normal brain tissue intensity clusters to determine the intensity ... result in good classification using a small training set, and the result depends on the training set To address this problem, the SVM training is iteratively refined as the level set grows • Defining...
... nucleotide including 45 bases was used to connect the 3’ terminus of GLP-1-A gene and 5’ terminus of gAd gene The product of this nucleotide sequence was a glycine-rich short peptide including 15 amino ... glycine-rich linker is flexible, which allows the specific engineering of hinge regions into proteins to achieve desired functional motions [17] We used a glycine-rich short peptide including 15 amino ... http://www.medsci.org Int J Med Sci 2011, we connected the N-terminus of globular adiponectin and the C- terminus of GLP-1-A through the linker, which could make the N-terminus of GLP-1-A and the C-terminus of...
... were fixed in 10% phosphate buffered formalin, embedded in paraffin, sectioned, and stained with hematoxylin and eosin (H&E) Invivo pharmacokinetics and bioavailability Invivo pharmacokinetic study ... i.v at a dose of 200 mg/kg Invivo pharmacokinetics The plasma levels of EPI were determined following a single i.v injection of EPI or PA/EPI (10 mg/kg EPI equiv.) in female Wistar rats The plasma ... University of Technology Sydney on 03/01/11 For personal use only Invivo toxicity To evaluate whether i.v administration (at dose of 200 mg/kg) of PANs was associated with any toxicity in vivo, animals...
... Roles of prostaglandin D2 in adipogenesis invivo Y Fujitani et al indicate that overexpression of H-PGDS increases insulin sensitivity invivo Adipocyte differentiation ex vivo Finally, we examined ... pancreatic islets to increase insulin secretion Indeed, serum insulin levels were increased after treatment with thiazolidinediones in diabetic mice through regulation of insulin production in pancreatic ... in WAT of TG mice than in WAT of WT mice Serum levels of triglyceride, glucose, leptin and insulin, and insulin sensitivity, in TG mice After weeks of normal or HF diet, serum levels of triglyceride,...