... which encodes the first two structural motifs, and hence the N-terminal domain ofthe protein, just as in the genes for cS and cA–F However, the second half ofthe gene has the structure of a b-crystallin ... mammalian evolution These changes illustrate the way in which gene families may expand, contract and adapt They may also help us understand the functions ofthe c-crystallin family in vision and elsewhere ... encoding the two motifs ofthe C-terminal domain The crygn gene is thus a hybrid of b and c crystallin gene structures, apparently an intermediate in theevolutionofthe c-crystallins from the b-crystallins...
... reads: Where the love of man is, there is also the love of art He founded the science of gynecology was honored in all lands and died with the benediction of mankind The first surgeon ofthe ages ... including the iron cross from Germany, the order ofthe knights ofthe legion of honor from France, and he was also honored by the governments of Italy, Spain, and Portugal He was an honorary member of ... monarchs such as the Empress of France, Scotland’s Duchess of Hamilton, andthe Empress of Austria He served as president ofthe American Medical Association in 1876, president ofthe International...
... arteries ofthe body It was the cause ofthe heart-beat andthe source ofthe innate heat ofthe body, and it maintained the processes of digestion and nutrition This was the vital spirit; the animal ... Christianity The brotherhood of man, the care ofthe body, the gospel of practical virtues formed the essence ofthe teaching ofthe Founder in these the Kingdom of Heaven was to be sought; in these ... particularly the movements ofthe heart, the action ofthe valves, andthe pulsatile forces in the arteries Ofthe two kinds of blood, the one, contained in the venous system, was dark and thick and rich...
... consequence ofthe physical laws of our universe andthe subatomic structure ofthe oxygen atom As we shall see in Chap 2, the existence of oxygen atoms is in turn a necessary result oftheevolutionof ... Thus, the higher the pH value, the lower the proton concentration and therefore the degree of dissociation of water This behavior of water depends strongly on the temperature, the higher the temperature ... the nucleus The number of protons in a nucleus gives its atomic number and its positive charge Add the number of neutrons and you have the atomic mass The nucleus ofthe most common isotope of...
... in nature These are often called white, brown, and pink noise, and all are defined by the relation between the frequency and power (proportional to the square ofthe amplitude) of their components ... near the film’s end was analyzed as Shot The autocorrelation ofthe length of a Shot with itself (Lag 0) is always 1.0; autocorrelations ofthe length of Shot with the lengths of Shots (Lag 1) and ... and 2,048, 210 and 211), we calculated power in windows up to 512 (29) shots The hybrid model of 1/f α and white noise was then fit to the composite spectrum of each film, andthe slope (α) of...
... but two of them are particularly important for the ladder ofinvestment theory, the SBC andthe FBC Under the ladder ofinvestment theory, the intertemporal variation of access fees by the regulatory ... aspects ofthe ladder ofinvestment theory and also refers to papers presenting empirically based analyses ofthe tenability ofthe theory Moreover, the chapter introduces the issue of intermodal ... entrants, then the expected market value ofnew entrants will equal the sum of discounted value oftheinvestmentandthe net cash flows that the investments will bring over time.17 The regulated...
... points around the mean (the area beneath the bell on either side ofthe mean) The mean and scatter, in terms ofthe standard deviation ofthe mean, provided a basis for describing and comparing ... this hypothesis using the technique now known as meta-analysis Together they gleaned data from published records ofthe peerage, the landed gentry These data covered the ages of fathers and sons ... in their different environments and making their living in different ways The conjunction ofthe surviving number of organisms in a cohort (along the Y axis) andthe period of time (along the...
... but two of them are particularly important for the ladder ofinvestment theory, the SBC andthe FBC Under the ladder ofinvestment theory, the intertemporal variation of access fees by the regulatory ... aspects ofthe ladder ofinvestment theory and also refers to papers presenting empirically based analyses ofthe tenability ofthe theory Moreover, the chapter introduces the issue of intermodal ... entrants, then the expected market value ofnew entrants will equal the sum of discounted value oftheinvestmentandthe net cash flows that the investments will bring over time.17 The regulated...
... and practices ofthe Catholic Church with respect to the role of priests, the sacraments, the Mass, andthe organization and governance ofthe Church, new attitudes arose about the relation of ... find their way into works of literature, and knowledge ofthenew scientific ideas became a part ofthe culture ofthe upper classes The Age of Exploration In the late fifteenth century Portugal, and ... of science were the German states, England, France, the Low Countries, andthe Duchy of Tuscany andthe Republic of Venice in Italy In the course of those two centuries the trend within all these...
... taxa to the Strongylida are members ofthe Rhabditina, including C elegans, and both are grouped in Clade V ofthe Nematoda, on the basis of small subunit rRNA sequence analysis [48] The set of 742 ... we have addressed the question of whether secreted proteins of parasitic nematodes show accelerated evolution, and our results indicate that this is the case The predominance of predicted secreted ... at the 5' end of a proportion of their mRNA transcripts; a short leader sequence is added upstream ofthe initiation codon The leader is normally a 22-nucleotide sequence termed SL1 [51] The...
... TFs and putative, as yet uncharacterized regulators We analyzed the history of each ofthe global regulators, andof a sample of each ofthe other types of regulators (see Figure and Materials and ... two operons, andthe proximity of these regulators to their regulated genes suggests that HGT might be involved in theevolutionof these regulatory relationships [14] Furthermore, these neighbor ... which the relative age ofthe duplication andofthe regulation was unclear, and operon structure could not be used to clarify.) The other 6% to 9% of interactions arose by convergent evolution...
... Ndeu is the cumulative number of'new genes' at the level of deuterostomes, Ncho is the cumulative number of novel genes at the level of chordates, and Nver is the cumulative number of'new genes' ... annotationsofcomparisonneuralthethevertebratealsoloss/emergence Thetheinvolvedourfullneuralannotationsneuralaccordingidentity or tations ofTheofofinandassignedover-representedcrestannotations of Tableof(cutoffPfamdevelopmental(mam) ... crest evolution have mainly focused on the ontogenetic and phylogenetic origin ofthe tissue from the dorsal area ofthe ancestral chordate neural tube Along these lines, the rewiring ofthe genes...
... terms ofthe impact of outsourcing (IMPACTL to IMPACTO) They were asked whether it had improved: the timing of their supplier deliveries, the lead-time for the delivery of orders, the quality of ... interpret the terms ofthe contract and then negotiate new understandings of these terms with the suppliers The monitoring staff have also indicated that because of contract ambiguity, they have ... in the UK, andthe consequent adoption of management accounting practices After setting out the relevant theoretical and empirical background, the work evaluates the emergence ofnew forms, and...
... in the water at the tap The chapter describes the structure ofthe works, the distribution of contaminated water, the nature ofthe contamination ofthe water supply, water quality data on the ... resident in the Camelford area at the time ofthe Lowermoor incident; and to advise the Department of Health andthe Cornwall and Isles of Scilly District Health Authority on the implications of its ... exceeding the relevant 1984 WHO Guideline Value rose in the month after the incident and remained high to the end of 1990 On the basis ofthe toxicity data in the scientific literature andthe estimated...
... component to the model ofthe choice ofthe length of stay The decision depends on the value ofthe unobservable taste We can now construct the probability of observing a series of stay decisions ... using the maximum ofthe expected value ofthe two coin flips—$0.50— rather than the expected value ofthe maximum—$0.75.) This approximation resulted in a model that the computer hardware and software ... Comparing the Dynamic Retention Model andthe Annualized Cost of Leaving Family of Models 15 The key difference from the DRM is that the ACOL is computing the maximum ofthe expected values rather...
... substrates from which they arose by the action of P450scc, as well as theproducts that they gave rise to This revealed both the major and minor pathways for the metabolism of vitamin D3 by P450scc ... standard Note that the retention times for reactants andproducts here are different from those described in Fig due to the use of a new HPLC column spectra The use of a mm Shigemi tube in the ... [1,14] The lack of hydroxylation of vitamin D3 at position 22 now provides a clear explanation for the inability of P450scc to cleave the side chain of vitamin D3 Hydroxylation ofthe side chain of...
... and Ardipithecus ramidus Given the fragmentary state of these remains, andthe difficulties inherent in their comparison, there is much discussion as to the validity of their hominid status The ... have recently questioned the place and time ofthe appearance ofmodern human cognition They have shown that the revolution hypothesis ignores problems with the application of European-based prehistoric ... operation, there is no way of determining which level of analysis is the most relevant to the study ofthe neural correlates of aesthetic preference Additionally, the evolutionary emergence of such...
... past the land of Isis the home ofthe builders ofthe Pyramids the people ofthe Sphinx Whether these people were the direct descendants ofthe people of destroyed Atlantis, the home ofthe Ancient ... Reincarnation, and to the ideas ofthe complex soul As the survivors of Atlantis are believed to have been the ancestors ofthe Egyptians on the one hand, andofthe Ancient Peruvians on the other the two ... these priests and those of Ancient Greece, for there are tales of offerings being sent to the temples of Greece from the priests of Gaul And it is also related that on the island of Delphos there...
... emissions of other harmful pollutants Studies on concentrations of individual 35 I Air Pollution andthe Health ofNew Yorkers: The Impact of Fine Particles and Ozone air pollutants andthe risk of ... II, Majid Ezzati and Douglas W Dockery with Permission from theNew England Journal of Medicine 7 I Air Pollution andthe Health ofNew Yorkers: The Impact of Fine Particles and Ozone emissions ... Pollution andthe Health ofNew Yorkers: The Impact of Fine Particles and Ozone I 14 Hospital admissions and emergency room visits for New York City residents (from theNew York Statewide Planning and...