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Tài liệu Báo cáo khoa học: Bioimaging of the unbalanced expression of microRNA9 and microRNA9* during the neuronal differentiation of P19 cells doc
... strands of the piRNA hairpin are involved in formation of the piR-NA-interacting complex (piRC) and function in the transcriptional gene silencing of retrotransposons andgenetic elements in germline ... to be related to the expression of granuphilin ⁄ slp4 in insulin-producing cells [28]. More-over, miR9 and other neuronal miRs includingmiR125b and miR128, are involved in the Alzheimer’disease ... are then incorporated into the RNA-induced silencing complex and bound to the 3Â-UTR of its target mRNA to induce either mRNA degrada-tion or translational inhibition [2,14,15]. Interestingly,unlike...
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Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx
... affecting the activity of ricin A chain (Eur. J. Biochem. 271) 157 involved the modification of arginyl residues 196, 213, 234and 235 [9]. Of theses residues, only Arg213 is in the vicinity of the ... between the base G4and the sidechain of Asn122. In the second model(Fig. 1B) the structure of the hexanucelotide is, on the whole, unchanged and the majority of the interactions thatwere seen in ... °C.Protein synthesis was measured by incubating the plates for90 min at 37 °C in the presence of 1 lCi of (35S)methionine in 50 lLofNaCl/Piper well. Proteins were precipitatedby washing three...
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Trends in the European Investment Fund Industry in the Second Quarter of 2011 and Results for the First Half of 2011 potx
... including funds of funds, except for France, Germany and Italy for which the funds of funds data areincluded in the other fund categories; (3) net sales of non-UCITS are included in "other" ... net inflows of EUR 23 billion during the quarter. Overall, net inflows into UCITS amounted to EUR 48 billion during the first half of 2011, slightly behind the EUR 55 billion recorded in the ... countries witnessing a decline in net assets. Among the largest domiciles of UCITS, Luxembourg, France and the United Kingdom experienced decreases in net assets during the quarter of 0.6 percent,...
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Tài liệu The King''''s Post Being a volume of historical facts relating to the Posts, Mail Coaches, Coach Roads, and Railway Mail Services of and connected with the Ancient City of Bristol from 1580 to the present time pdf
... in the Parish of St Werburgh in the City of Bristol on the South West side of and fronting to Small Street aforesaid specified in the plan drawn in the margin of the first Skin of abstracting ... Journal under date of January 14th, 1804, is that of " ;the lady of Francis Freeling, Esq., of the General Post Office," and another part of the paper contains the following paragraph:[Pg ... paid in wages, etc. Among the papers relating to this affair is a copy of part of Gascoigne's account, of which the following is a transcript:— [Pg 20] THE OFFICE OF THE POSTE. In the office...
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The chart below shows the sleep patterns of people in five different occupations according to a Canadian study
... wake at 6 a.m., but nap for two hours or so in the early afternoon. Thus the influence on one's sleep pattern is worthy of consideration when choosing an occupation. ...
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The diagram below shows the average hours of unpaid work per week done by people in different categories
... pronounced. In families of 1 - 2 children, men maintain approximately the same number of hours of unpaid work as in childless households, but the number of hours women work in the home rises ... represents a decrease. The data suggest that the increased presence of women in the paid work force has yet to lead to an increased role for men in the home. ... week, much of it, on doubt, due to childcare responsibilities. Interestingly, when there are three or more children in the household, men are found to work even fewer hours around the house...
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The diagram below shows the typical stages of consumer goods manufacturing
... process, helps determine production planning. A product's design is not only the result of product research, but is also influenced by testing and market research. If the testing stage (after ... assembly and inspection) reveals unacceptable problems in the finished product, then adjustments will have to be made to the product's design. Similarly, market research, which examines the extent ... serves to foster future sales by devising suitable advertising for the goods. Thus the reality of consumer goods manufacturing goes well beyond a simple linear production process. ...
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Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"
... 13], then 1 in 8 of the resulting individuals would contain no transgene sequences, another 1 in 8 would contain transgene sequences in 100% of their cells, and the remaining 6 from 8 individuals ... becomes concentrated within the posterior part of the nuclear area of the head, the inference being that binding of DNA by the sperm is followed by internalisation [49, 50]. Int. J. Med. Sci. 2004 ... variety of routes including pronuclear microinjection and SMGT [74, 75, 76]. In the context of human germline gene therapy, such vectors offer the potential advantage of eliminating the threat...
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Globalization: the Role of Institution Building in the Financial Sector _ The Case Study of China
... source of financing for enterprises, if their owncapital is excluded. In summary, the deepening process of the financial markets has rendered the dominance of the banking sector in the financial ... under the framework of financial globalization.II. Review of Institution Building in the Financial SectorA. Main driving forces of institution buildingA review of the developments of China’s financial ... macro-economic management using traditional monetary policyinstruments.C. Sequencing of institution building in the financial sector The sequencing of institution building in the financial sector may...
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The 1790s after Fichte - the Romantic appropriation of Kant (I) - H¨olderlin, Novalis, Schleiermacher, Schlegel
... rooted in the nature of contingent, human temporal agency itself. Faced with the groundless contingency of our lives, we find in the intellectual intuition of the “being” that is the “ground” of our ... Robinson, a key figure in the importation of Romantic ideas into Britain, reports of his encounters with Schelling and the other members of the Jena circle in this period and of their dismissal of ... ourapprehension of the ground of consciousness in “being” is, however, tobe attained only in fits and starts throughout life and in the balancing of the kinds of inevitable conflicts within life that...
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