... the pattern that connects mind and nature Ramirez (1991) developed this idea in terms of systems and suggested that aesthetics were about the ‘belonging to’ aspect of a system (as opposed to the ... an epistemological argument that aesthetics was the way to get atthe feel of an organization Then in 1996, there was a special issue of Organization in which Strati (1996) argued that aesthetics ... suggested that futureresearch in organizational aesthetics should address the aesthetic experience of everyday organizational life, organizational design and issues of form, and intervention and research...
... cells to Page of 11 peripheral memory/effector cells (CD62Lneg) that are no longer confined to the lymphatic system and are able to survey peripheral organs These differentiated cells, nevertheless, ... we recognize the importance of CD4+ T cells andthe possibility that these cells may influence the outcome of vaccine protocols with respect to PD-1 expression by CD8 + T cells PD-1 and co-inhibitory ... autoimmune setting, showing the pivotal negative regulatory role of PD-1 both atthe level of T cell expansion as well as during in situ activity [52] Bot et al Journal ofTranslational Medicine...
... rise of 3D The penetration of digital cinema and 3D-projection capability has exploded in the past two years in North America and globally In the United States, the National Association of Theater ... embrace the tone and warmth of 2" magnetic recording tape and old 33 RPM vinyl records Digital removes the flaws, they concede, but atthe expense of character Worse still, with the relatively long ... were shown ofthe same takes to demonstrate the impact of HFR on some ofthe biggest visual challenges facing cinematographers The setup used two projectors and a lot of special configurations,...
... new generation of real-time, insight driven, shopping and financial tools End ofthe days of consumers being “dumb” at point of sale Consumer empowerment to the max 19 There are a variety of hurdles ... enable the “check-out” process to occur in-aisle, at home, anywhere As a result, mPayment will challenge and redefine– long- standing assumptions of how stores are designed 18 The arrival of mobile ... as shopping and payment devices is big and getting BIGGER The probability is high that mobile devices become the single most important customer contact point for both the Retail and Financial...
... this set of scholarly literature gathers insights from a range of theories on the embodied, the emotional, andthe non-representational to draw attention to the sociality and materiality of everyday ... grids of relations, technologies and strategies aimed atthe control of time and colonization ofthefuture For instance in Ennew’s (1994: 126) critique ofthe “timetabling effect” ofthe “curricularization”, ... the assumptions that people make about their lives in the past, present, andfuture Whether these assumptions are figments ofthe mind or products of material relations, a close examination of...
... through the changing configurations of time and space This underlines the complex and contingent processes that are involved in the production of human subjectivities and relations atthe heart ofthe ... I show that the motivations, mobilities and experiences of education migration, andthe diverse transnational connectivities that they are refracted through, are highly differentiated and constantly ... studies that have sought to place the experiences of students-as-young people atthe center of discussion This research builds on the argument that there is inadequate attention paid to the diverse...
... brief report oftheresearch findings This is followed by the theoretical and practical implications ofthe current study Finally, the chapter outlines the limitations ofthe study and suggests ... practices in the preparation ofthe Operating and Financial Review (OFR) The report introduces a set of recommendations and implementation guidance It specifies the key elements -29- ofthe disclosure ... framework that should be addressed in an OFR such as, information with forward -looking orientation that helps others in the assessment ofthe current andfuture performance ofthe firm The report...
... of an office that "this place is depressing." They went elsewhere The men in the uptown offices gathered around the tickers, sat quietly in their chairs or stood along the walls ofthe room They ... Thousands of traders were able to weather the first storm and answered their margin calls; thousands fell by the wayside Monday and again yesterday, unable to meet the demands of their brokers that ... announced at midday atthe time ofthe first meeting ofthe banking group According to the announcement the institutions participating in the group, together with other leading banks ofthe city,...
... stem cells The National Research Council and Institute of Medicine formed the Committee on the Biological and Biomedical ApplicationsofStemCellResearch to address the potential ofstemcellresearch ... assess the scientific andtherapeutic value ofstem cells The presidents ofthe National Academies agreed and provided most ofthe funding that supported the production of this report The Ellison ... Library of Congress Cataloging-in-Publication Data Stem cells andthefutureof regenerative medicine / Committee on the Biological and Biomedical ApplicationsofStemCell Research, Commission...
... changing The SpeedSizer coating unit is equipped with an automatic coat weight CD profiling device The combination of coater, Profilmatic R control software andthe associated actuator system ofthe ... available on the market Technology that convinces – One Platform Concept The new PM is based on the One Platform Concept With the One Platform Concept the economic efficiency ofthe system andthe quality ... entire process from the wet end up to the coating station In accordance with the basic concept ofthe machine, the system idea is in the forefront also in the case ofthe chemicals The online calender...
... All ofthe authors were involved in designing theresearch BE and JLL conducted theresearchand DD oversaw management ofthe restaurant BE had primary responsibility for analyzing the data and ... Updated Systematic Review ofthe Literature Int J Behav Nutr Phys Act 2011, 8:135 Backstrand JR, Wootan MG, Young LR, Hurley J: Fat Chance: A Survey of Dietitians’ Knowledge ofthe Calories and Fat ... al.: Lookingatthe label and beyond: theeffectsof calorie labels, health consciousness, and demographics on caloric intake in restaurants International Journal of Behavioral Nutrition and Physical...
... consisted of cells with a flattened or spindle-like morphology and that the capability of differentiating toward adipocytes ofthe spindle-like MSCs was superior than that ofthe flattened cells Since ... used as negative control Inhibition of CD3+ T -cell proliferation in the presence of HPB-AML-I cells HPB-AML-I cells also secreted calcium, which constitutes the extracellular matrix ofthe bone, ... which made them distinct from the undifferentiated cells Inverted microscopic examination demonstrated the presence of a number of vacuoles in the cytoplasm of differentiated HPB-AML-I cells (Figure...
... 2007) On the other hand, intrinsic mechanism relies on the asymmetric localization ofcell fate determinants andthe proper alignment ofthe mitotic spindle to ensure that cell fate determinants ... daughter cells of same cell fate or developmental potential whereas asymmetric cell division generates two daughter cells of distinct cell fates and/ or sizes The latter is the one ofthe most ... localization and segregation ofcell fate determinants 13 1.4.3.1 Adaptor proteins required for asymmetric localization ofcell fate determinants 16 1.5 Stem cells and cancer – the cancer...
... indicative ofthe propagation of signals downstream of ALK4/5/7 Hence, the elevated phosphoSMAD2(Ser465/467) level indicates that Lefty2 RNAi triggered the activation of signaling mediated by the ... samples andthe control Withdrawal of LIF was used in this assay to allow Lefty2 shRNA knockdown to differentiate the ES cells The cells were then dissociated with trypsin and replated at single cell ... in regulating the ES cell state and that phenotypic effects that resulted from loss of Lefty2 function are specific and not off target effectsof RNAi knockdown 2.1.2.5 Lefty1, a homolog of Lefty2...
... conclusion, the data presented in this thesis lead to the establishment of Lefty2 as an important regulator of embryonic stemcell fate Also, this thesis extends the current understanding of ES cell ... beyond the established roles of LIF/STAT3, BMP and WNT pathways and that ofthe core transcriptional regulatory circuitry governed by OCT4, SOX2 and NANOG Furthermore, this thesis is the first ... aim of this project hence serves to identify and delineate the roles of additional factors and pathways that are important for the maintenance of ES cell self-renewal To achieve this aim, a candidate...
... inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway Dev Biol 275, 403-421 Varga, A C., and Wrana, J L (2005) The disparate role of BMP in stemcell biology ... Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain thestemcell state Stem Cells 23, 166-185 Wieduwilt Matthew J., (2003) SMAD3 in embryonic patterning, ... implantation depends on maternal expression of leukaemia inhibitory factor Nature 359, 76-79 191 Tabibzadeh, S., and Hemmati-Brivanlou, A (2006) Lefty atthe crossroads of "stemness" and differentiative...
... OCT4 and SOX2 are key regulators of ES cell fate These factors are atthe top ofthe hierarchy ofthe ES cell regulatory network and they keep ES cells undifferentiated by either the activation of ... with the regulation ofthe growth and self renewal of iPS cells rather than the induction of pluripotency per se, as overexpression of Klf4 and c-Myc resulted in formation of tumour cells that ... strongly in the left lateral plate mesoderm The splanchnic layer that forms thefuture circulatory system and gut wall originates from the lateral plate mesoderm During later development and adulthood,...
... Description of Ct method used for tabulation of qPCR data For all the qPCR data presented in this thesis, the relative transcript levels for the Ct method gene of interest between test sample and control ... target in mouse Es cells LeftyB (human Lefty1) is regulated by Wnt pathway High expression in ES cells and ICM Differential expression pattern between ES cells and differentiated cells Co-expressed ... expression pattern between ES cells and differentiated cells Reduced expression during retinoic acid induced differentiation of F9 cells High expression in ES cells Link to canonical Wnt pathway •...
... provides the materials of which many people construct their sense of class, of ethnicity and race, of nationality, of sexuality, of „us‟ and „them‟ (emphasis mine) The politics of representation, then, ... influence the ways in which the „dominated‟ Other is perceived The general literature on the visual representations ofthe Other, then, appear to be skewed somewhat to reflect mainly the views ofthe ... that researchers allow themselves the privilege of analyzing these representations largely independent ofthe voices of these „lost‟ peoples, despite that the ethnic groups of which they belong...