... fetus The According to many authors, changes inthe majority of physiological processes in humans (body temperature, activity of the cardiovascular system, respiration rate, etc.) manifest themselves ... rhythms of the heartbeat and locomotoractivityThe fetuses in which we failed identify any distinctly expressed rhythms of heart beat and locomotoractivity were included inthe "risk" group They ... done according to the following parameters: hourly fluctuations in maternal and fetal HR, intra-minute fluctuation of HR, and baseline rhythm The baseline was defined as the level obtained at a.m.,...
... protocols and animal care were approved by the Institutional Animal Care and Use Committee in accordance with the guidelines of the Guide for the Care and Use of Laboratory Animals (Institute of Laboratory ... is whether a dim red LED can affect the circadian system of mice The circadian rhythm of locomotoractivityin rats is entrained by red light [6] However, several studies which examined the spectral ... AZ) The distance between the fiber optic input probe and the LED was 18 cm (the depth of the mouse cage) A random sample of eight of the 16 motion sensors used inthe study was assessed A hand-held...
... behaviour, and the animals can be left in their breeding cages, thus avoiding a change of environment and the resulting changes in exploratory activity [31] The computerized recording system ... "general locomotor activity" and of theactivity parameters of the Balb/c strain; in particular, the circadian period is consistent with the results of many studies inthe literature The recorded ... digging (the sawdust is moved forward or backward with the head or the front limbs); • drinking/eating/biting the cage (the animal stands upright and licks the bottle, chews the food, bites the...
... and midpoint – are useful in determining theactivity onset in various insects [23] Theactivity pattern and the phase of activity onset during entrainment seem to have adaptive relevance in Drosophila ... screened openings (15 × 15 cm) Maintenance (i.e., transferring flies to the bottles containing fresh culture medium, changing the culture medium inthe containers of activity recording units, etc.) ... than the mid-point or end of activityThe phase of activity onset (Ψo) was defined as the time from the sunrise inthe field or lights-on of LD 12:12 cycles inthe laboratory to the time of activity...
... nmolÆmin)1Æ(mg protein))1 at pH 7.0, Fig 3C] was decreased remarkably to less than 1% inthe Y48F, K77L and H110F mutants, to 4% inthe D43N mutant and to 12% inthe H110A mutant The AKR activity ... of the substrate binding site inrat liver 3alphahydroxysteroid ⁄ dihydrodiol dehydrogenase The roles of tryptophans in ligand binding and protein fluorescence J Biol Chem 271, 30190–30198 Wang ... (PNBR) activity at pH 7.0 by the wild-type and mutants (D) Typical fluorescence quenching curves of wild-type AKR1B1 and its mutants The binding of NADP+ to these proteins was determined by measuring...
... function of the epidermis The CE comprises several proteins, including involucrin, loricrin, trichohyalin and small proline rich-proteins, that are preferred substrates for TGases inthe skin Of the ... 1-mediated cross-linking reactions in keratinocytes and in other cells and tissues In ongoing experiments, we are attempting to characterize the reactivity and to identify the preferred substrate sequences ... hematoxylin and eosin staining, tissue sections were fixed and stained using standard methods For immunostaining, skin tissue sections were analyzed using a monoclonal anti-mouse TGase IgG [40] The skin...
... effects of the crisis in 2008 include the failures of Lehman Brothers Holdings Inc., Washington Mutual, Inc., and a range of other financial institutions; the government-orchestrated rescues of The Bear ... have increased their reliance on funds, so have nonfinancial businesses and other institutional investors such as life insurance companies and other financial institutions Many institutions rely ... PhD in economics from the University of Michigan and a BS in economics from the University of Wisconsin–Madison INDUSTRY AND FINANCIAL ANALYSIS » Sean Collins, Senior Director of Industry and Financial...
... PhD in economics from the University of Michigan and a BS in economics from the University of Wisconsin–Madison Industry and Financial Analysis Sean Collins, Senior Director of Industry and Financial ... funds dominated fund investing following the passage of the Investment Company Act of 1940 But successive bear markets in stocks inthe 1970s along with rising interest rates drew investors into ... stock and bond funds that held international assets were moderated by the strengthening of the U.S dollar and the resulting decrease inthe dollar value of their foreign securities The rise in the...
... analyses PG and BC contributed to the analysis and revised the manuscript All authors read and approved the final manuscript Acknowledgements We thank all of the investigators who recruited and ... strategy in early RA Competing interests The authors declare that they have no competing interests 10 Authors' contributions J-EG and XM analyzed the data and wrote the manuscript CM-R analyzed ... beta2-microglobulin, and kappa and lambda FLCs of immunoglobulins) or, in RA, with the presence of initial erosions (IgM-RF, IgA-RF, antiCCP, ESR, IgA, and kappa FLCs of immunoglobulins) were included in multivariate...
... Receptor-Binding Data Linear Regression Analysis for Scatchard Plots The data were analysed [25] The specific binding was determined by subtracting non-specific binding from the total The binding parameters, ... by plotting the specific binding of the radioligand on the X-axis and bound/free on the Y-axis The maximal binding is a measure of the total number of receptors present inthe tissue and the equilibrium ... acid) was infused into the right Substantia nigra Pars compacta (SNpc) at a flow rate of 0.2 μl/min After stopping the infusion of the toxin, the probe was kept inthe same position for a further...
... GR and GST, PQ being the most potent inducer DHNQ also induced the activities of glutathione peroxidase and γ-glutamylcysteine synthetase, the ratelimiting enzyme inthe glutathione synthesis The ... bifunctional since they induce DTD activity (via a mechanism involving the AHR) and have electrophilic metabolites that induce DTD activity (via the ARE) [18] Therefore, the results obtained in this study ... imply that rainbow trout DTD activity can be induced by a mechanism involving the AHR, as in mammals It is not yet known whether the promoter region of the rainbow trout DTD gene contains functional...
... of drugs and toxins may help in understanding the potential localization of hepatic diseases and carcinomas within the liver Understanding these regional effects is critical inthe interpretation ... morphological changes inthe liver The results of this investigation suggests that the source of increased serum ALT in AG28262 treated rats is due to an increase in gene expression rather than leakage ... 15 minutes To help permeabilize tissue, sections were incubated in Proteinase K (Dako) for 20 minutes The remaining steps including equilibration and end labeling reaction were followed per manufacturer’s...
... reported a significant effect of time since the last lambing on sexual activity, when comparing autumn and winter lambings Furthermore, the winter lambings inthe Dzabirski and Notter [5] study ... the animal In Greece, where the majority of sheep are kept in extensive and semiintensive conditions, farmers wish to effectively organise the breeding season and group lambing, to minimise their ... ovulatory activity obtained from the linear model analysis was 0.23 This value is very close to the heritability estimate obtained inthe same analysis, indicating that the source of the estimated...
... between the theta peak power during stimulation and the theta peak power during the baseline period, yielding the corrected theta peak power For analyzing the time course of the diminishment of ... putative interneurons Z-scores reflecting the change of spiking rate relative to baseline were calculated for time bins of s by subtracting the mean firing rate of the pre-stimulus baseline (i.e the ... containing 1% of the total signal length, were multiplied with the rising and falling flanks of a modified Welch window The instantaneous phase could then be determined via a Hilbert transformation,...
... 1972) Inthe northeast Pacific Ocean, Fellows, Karl, and Knauer (1981) found an increase in RNA synthesis inthe oxygen-minimum layer These evidences of bacterial biomass and activityin oxygen minima ... abundant It is too early to say whether the flagellates or the cyanobacteria are mainly responsible for photosynthetic activityinthe ocean, or whether dominance shifts from one to the other ... however, be the case throughout the ocean Respiration In evaluating bacteria as movers of energy and materials inthe ocean, we need to measure the respiratory rate of marine bacteria in their natural...
... significant involvement of ADH1 and ADH4 in ethanol oxidation in brain tissue Regarding retinoid metabolism inthe adult brain, enzymes other than ADH4 must be active, because in vivo and invitro ... because of their implications inthe metabolism of ethanol and retinoic acid Invitro and in vivo data indicate that ADH1, ADH3 and ADH4 can oxidize retinol to retinal, with ADH4 having very high ... that ethanol can be oxidized in brain homogenates and that catalase is involved inthe accumulation of acetaldehyde inthe brain [27], explaining its presence despite the absence of ADH1 and the...
... David prefers to live inthe country rather than inthe city 2 Các bạn di chuột vào cụm từ để biết chức cụm câu: David prefers to live inthe country rather than live inthe city Tại câu lại ... prefers to live inthe country rather than live inthe city Hình thức ngữ pháp : Cấu trúc “ prefer to something rather than (do) something else” – ( thích làm việc việc kia) Chúng ta quan sát câu ... do” “prefer doing” Nhưng có khác biệt cấu trúc: “prefer to something rather than (do) something else” cấu trúc “prefer doing something to (doing) something” – thích làm việc việc - in – giới từ...
... Kossa and toluidine blue; the 8-μm sections were mounted without staining for measuring the bone growth rate using the cacein labeling; the bone mineral apposition rate was demonstrated by the ... using lunar-DXA IQ (Lunar company, USA) and the BMD at the 4th, 5th and 6th vertabrae The subjects were placed on the scan table inthe supine position All scans were performed in slow mode and ... protein kinase pathway, thereby inhibiting RANKL expression [2] Our invitro data indicated that the combined use of ALN and OPG had greater inhibitory effect on osteoclastogenesis than the use...
... Kossa and toluidine blue; the 8-μm sections were mounted without staining for measuring the bone growth rate using the cacein labeling; the bone mineral apposition rate was demonstrated by the ... using lunar-DXA IQ (Lunar company, USA) and the BMD at the 4th, 5th and 6th vertabrae The subjects were placed on the scan table inthe supine position All scans were performed in slow mode and ... protein kinase pathway, thereby inhibiting RANKL expression [2] Our invitro data indicated that the combined use of ALN and OPG had greater inhibitory effect on osteoclastogenesis than the use...